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Volumn 965, Issue , 2013, Pages 143-156

Colorimetric detection of senescence-associated β galactosidase

Author keywords

Aging; Biomarker; Cellular senescence; EdU labeling; Immunostaining; SA gal

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; CELL MARKER; EDOXUDINE; 4',6 DIAMIDINO 2 PHENYLINDOLE; CARBANILAMIDE DERIVATIVE; ETHYLENE DIUREA; INDOLE DERIVATIVE;

EID: 84878852565     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-239-1_8     Document Type: Article
Times cited : (105)

References (48)
  • 1
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120:513-522
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 2
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier F, Campisi J (2011) Four faces of cellular senescence. J Cell Biol 192:547-556
    • (2011) J Cell Biol , vol.192 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 3
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25:585-621
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 4
    • 0035843952 scopus 로고    scopus 로고
    • Cell biology. Telomere capping-one strand fits all
    • de Lange T (2001) Cell biology. Telomere capping-one strand fits all. Science 292:1075-1076
    • (2001) Science , vol.292 , pp. 1075-1076
    • De Lange, T.1
  • 5
    • 1842789989 scopus 로고    scopus 로고
    • Mechanisms of cellular senescence in human and mouse cells
    • Itahana K, Campisi J, Dimri GP (2004) Mechanisms of cellular senescence in human and mouse cells. Biogerontology 5:1-10
    • (2004) Biogerontology , vol.5 , pp. 1-10
    • Itahana, K.1    Campisi, J.2    Dimri, G.P.3
  • 6
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88:593-602
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 7
    • 0032192153 scopus 로고    scopus 로고
    • Senescence of human fibroblasts induced by oncogenic Raf
    • Zhu J, Woods D, McMahon M, Bishop JM (1998) Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev 12:2997-3007
    • (1998) Genes Dev , vol.12 , pp. 2997-3007
    • Zhu, J.1    Woods, D.2    McMahon, M.3    Bishop, J.M.4
  • 8
    • 0033989829 scopus 로고    scopus 로고
    • Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor
    • Dimri GP, Itahana K, Acosta M, Campisi J (2000) Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor. Mol Cell Biol 20:273-285
    • (2000) Mol Cell Biol , vol.20 , pp. 273-285
    • Dimri, G.P.1    Itahana, K.2    Acosta, M.3    Campisi, J.4
  • 10
    • 0141866708 scopus 로고    scopus 로고
    • Superoxide dismutase 1 knock-down induces senescence in human fibroblasts
    • Blander G, de Oliveira RM, Conboy CM, Haigis M, Guarente L (2003) Superoxide dismutase 1 knock-down induces senescence in human fibroblasts. J Biol Chem 278:38966-38969
    • (2003) J Biol Chem , vol.278 , pp. 38966-38969
    • Blander, G.1    De Oliveira, R.M.2    Conboy, C.M.3    Haigis, M.4    Guarente, L.5
  • 11
    • 0032524563 scopus 로고    scopus 로고
    • Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: P53 and Rb control G1 arrest but not cell replication
    • Chen QM, Bartholomew JC, Campisi J, Acosta M, Reagan JD, Ames BN (1998) Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem J 332(Pt 1):43-50
    • (1998) Biochem J , vol.332 , Issue.PART 1 , pp. 43-50
    • Chen, Q.M.1    Bartholomew, J.C.2    Campisi, J.3    Acosta, M.4    Reagan, J.D.5    Ames, B.N.6
  • 12
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • Di Leonardo A, Linke SP, Clarkin K, Wahl GM (1994) DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev 8:2540-2551
    • (1994) Genes Dev , vol.8 , pp. 2540-2551
    • Di Leonardo, A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 13
    • 0032485213 scopus 로고    scopus 로고
    • Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
    • Robles SJ, Adami GR (1998) Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts. Oncogene 16:1113-1123
    • (1998) Oncogene , vol.16 , pp. 1113-1123
    • Robles, S.J.1    Adami, G.R.2
  • 14
    • 0032496373 scopus 로고    scopus 로고
    • Features of replicative senescence induced by direct addition of antennapediap16INK4A fusion protein to human diploid fibroblasts
    • Kato D, Miyazawa K, Ruas M, Starborg M, Wada I, Oka T, Sakai T, Peters G, Hara E (1998) Features of replicative senescence induced by direct addition of antennapediap16INK4A fusion protein to human diploid fibroblasts. FEBS Lett 427:203-208
    • (1998) FEBS Lett , vol.427 , pp. 203-208
    • Kato, D.1    Miyazawa, K.2    Ruas, M.3    Starborg, M.4    Wada, I.5    Oka, T.6    Sakai, T.7    Peters, G.8    Hara, E.9
  • 18
    • 20444370974 scopus 로고    scopus 로고
    • What has senescence got to do with cancer?
    • Dimri GP (2005) What has senescence got to do with cancer? Cancer Cell 7:505-512
    • (2005) Cancer Cell , vol.7 , pp. 505-512
    • Dimri, G.P.1
  • 20
    • 34247860915 scopus 로고    scopus 로고
    • Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
    • Cosme-Blanco W, Shen MF, Lazar AJ, Pathak S, Lozano G, Multani AS, Chang S (2007) Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence. EMBO Rep 8:497-503
    • (2007) EMBO Rep , vol.8 , pp. 497-503
    • Cosme-Blanco, W.1    Shen, M.F.2    Lazar, A.J.3    Pathak, S.4    Lozano, G.5    Multani, A.S.6    Chang, S.7
  • 21
    • 34247581288 scopus 로고    scopus 로고
    • Short telomeres limit tumor progression in vivo by inducing senescence
    • Feldser DM, Greider CW (2007) Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell 11:461-469
    • (2007) Cancer Cell , vol.11 , pp. 461-469
    • Feldser, D.M.1    Greider, C.W.2
  • 27
    • 79551683487 scopus 로고    scopus 로고
    • Cellular senescence: Putting the paradoxes in perspective
    • Campisi J (2011) Cellular senescence: putting the paradoxes in perspective. Curr Opin Genet Dev 21:107-112
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 107-112
    • Campisi, J.1
  • 29
    • 0037439071 scopus 로고    scopus 로고
    • Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform
    • Cao L, Li W, Kim S, Brodie SG, Deng CX (2003) Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform. Genes Dev 17:201-213
    • (2003) Genes Dev , vol.17 , pp. 201-213
    • Cao, L.1    Li, W.2    Kim, S.3    Brodie, S.G.4    Deng, C.X.5
  • 30
    • 0037382970 scopus 로고    scopus 로고
    • Cellular senescence in the pathogenesis of benign prostatic hyperplasia
    • Castro P, Giri D, Lamb D, Ittmann M (2003) Cellular senescence in the pathogenesis of benign prostatic hyperplasia. Prostate 55:30-38
    • (2003) Prostate , vol.55 , pp. 30-38
    • Castro, P.1    Giri, D.2    Lamb, D.3    Ittmann, M.4
  • 31
    • 0034051249 scopus 로고    scopus 로고
    • Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia
    • Choi J, Shendrik I, Peacocke M, Peehl D, Buttyan R, Ikeguchi EF, Katz AE, Benson MC (2000) Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia. Urology 56:160-166
    • (2000) Urology , vol.56 , pp. 160-166
    • Choi, J.1    Shendrik, I.2    Peacocke, M.3    Peehl, D.4    Buttyan, R.5    Ikeguchi, E.F.6    Katz, A.E.7    Benson, M.C.8
  • 34
    • 1642561702 scopus 로고    scopus 로고
    • Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney
    • Melk A, Schmidt BM, Takeuchi O, Sawitzki B, Rayner DC, Halloran PF (2004) Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney. Kidney Int 65:510-520
    • (2004) Kidney Int , vol.65 , pp. 510-520
    • Melk, A.1    Schmidt, B.M.2    Takeuchi, O.3    Sawitzki, B.4    Rayner, D.C.5    Halloran, P.F.6
  • 39
    • 38149103006 scopus 로고    scopus 로고
    • High NaCl promotes cellular senescence
    • Dmitrieva NI, Burg MB (2007) High NaCl promotes cellular senescence. Cell Cycle 6:3108-3113
    • (2007) Cell Cycle , vol.6 , pp. 3108-3113
    • Dmitrieva, N.I.1    Burg, M.B.2
  • 40
    • 0033730616 scopus 로고    scopus 로고
    • Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells
    • Kurz DJ, Decary S, Hong Y, Erusalimsky JD (2000) Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells. J Cell Sci 113(Pt 20):3613-3622
    • (2000) J Cell Sci , vol.113 , Issue.PART 20 , pp. 3613-3622
    • Kurz, D.J.1    Decary, S.2    Hong, Y.3    Erusalimsky, J.D.4
  • 42
    • 0014800006 scopus 로고
    • Morphologic changes accompanying senescence of cultured human diploid cells
    • Robbins E, Levine EM, Eagle H (1970) Morphologic changes accompanying senescence of cultured human diploid cells. J Exp Med 131:1211-1222
    • (1970) J Exp Med , vol.131 , pp. 1211-1222
    • Robbins, E.1    Levine, E.M.2    Eagle, H.3
  • 43
    • 0015611629 scopus 로고
    • Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence
    • Brunk U, Ericsson JL, Ponten J, Westermark B (1973) Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence. Exp Eye Res 79:1-14
    • (1973) Exp Eye Res , vol.79 , pp. 1-14
    • Brunk, U.1    Ericsson, J.L.2    Ponten, J.3    Westermark, B.4
  • 44
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • Narita M, Nunez S, Heard E, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW (2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113:703-716
    • (2003) Cell , vol.113 , pp. 703-716
    • Narita, M.1    Nunez, S.2    Heard, E.3    Lin, A.W.4    Hearn, S.A.5    Spector, D.L.6    Hannon, G.J.7    Lowe, S.W.8
  • 46
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: The dark side of tumor suppression
    • Coppe JP, Desprez PY, Krtolica A, Campisi J (2010) The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 5:99-118
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppe, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 47
    • 34548799705 scopus 로고    scopus 로고
    • Methods to detect biomarkers of cellular senescence: The senescence-associated beta-galactosidase assay
    • Itahana K, Campisi J, Dimri GP (2007) Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay. Methods Mol Biol 371:21-31
    • (2007) Methods Mol Biol , vol.371 , pp. 21-31
    • Itahana, K.1    Campisi, J.2    Dimri, G.P.3
  • 48
    • 40649111377 scopus 로고    scopus 로고
    • A chemical method for fast and sensitive detection of DNA synthesis in vivo
    • Salic A, Mitchison TJ (2008) A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A 105:2415-2420
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2415-2420
    • Salic, A.1    Mitchison, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.