Polymorphisms in oxidative stress genes, physical activity, and breast cancer risk

Cancer Causes and Control

Volumn 23, Issue 12, 2012, Pages 1949-1958

  McCullough, Lauren E ^a   Santella, Regina M ^b   Cleveland, Rebecca J ^c   Bradshaw, Patrick T ^a   Millikan, Robert C ^a   North, Kari E ^a   Olshan, Andrew F ^a   Eng, Sybil M ^b   Ambrosone, Christine B ^d   Ahn, Jiyoung ^e   Steck, Susan E ^f   Teitelbaum, Susan L ^g   Neugut, Alfred I ^b   Gammon, Marilie D ^a  

^a University of North Carolina at Chapel Hill   (United States)

^b Columbia University ^*  (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f UNIVERSITY OF SOUTH CAROLINA   (United States)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Catalase; Epidemiology; Oxidative stress; Physical activity

Indexed keywords

CATALASE; CATECHOL METHYLTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; MANGANESE SUPEROXIDE DISMUTASE; MYELOPEROXIDASE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER RISK; CATALASE GENE; CATECHOL METHYLTRANSFERASE GENE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; GENOTYPING TECHNIQUE; GLUTATHIONE PEROXIDASE GENE; GLUTATHIONE TRANSFERASE A1 GENE; GLUTATHIONE TRANSFERASE M1 GENE; GLUTATHIONE TRANSFERASE P1 GENE; GLUTATHIONE TRANSFERASE T1 GENE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MANGANESE SUPEROXIDE DISMUTASE GENE; MYELOPEROXIDASE GENE; ONCOGENE; OUTCOME ASSESSMENT; OXIDATIVE STRESS GENE; PHYSICAL ACTIVITY; POSTMENOPAUSE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MIDDLE AGED; MOTOR ACTIVITY; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; YOUNG ADULT;

EID: 84878850049     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-012-0072-1     Document Type: Article

References (57)

1. Ambrosone CB (2000) Oxidants and antioxidants in breast cancer. Antioxid Redox Signal 2:903-917
2. Kang DH (2002) Oxidative stress, DNA damage, and breast cancer. AACN Clin Issues 13:540-549
3. Behrend L, Henderson G, Zwacka RM (2003) Reactive oxygen species in oncogenic transformation. Biochem Soc Trans 31:1441-1444. doi: 10.1042/
4. Caporaso N (2003) The molecular epidemiology of oxidative damage to DNA and cancer. J Natl Cancer Inst 95:1263-1265
5. Halliwell B (2000) The antioxidant paradox. Lancet 355:1179-1180. doi: 10.1016/S0140-6736(00)02075-4
6. Martin KR, Barrett JC (2002) Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity. Hum Exp Toxicol 21:71-75
7. Cooke MS, Evans MD, Dizdaroglu M et al (2003) Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 17:1195-1214. doi: 10.1096/fj.02-0752rev
8. Klaunig JE, Kamendulis LM (2004) The role of oxidative stress in carcinogenesis. Annu Rev Pharmacol Toxicol 44:239-267. doi: 10.1146/annurev. pharmtox.44.101802.121851
9. Tas F, Hansel H, Belce A et al (2005) Oxidative stress in breast cancer. Med Oncol 22:11-15. doi: 10.1385/MO:22:1:011
10. Forsberg L, Lyrenas L, de Faire U et al (2001) A common functional C-T substitution polymorphism in the promoter region of the human catalase gene influences transcription factor binding, reporter gene transcription and is correlated to blood catalase levels. Free Radic Biol Med 30:500-505
11. Ahn J, Gammon MD, Santella RM et al (2005) Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use. Am J Epidemiol 162:943-952. doi: 10.1093/aje/kwi306
12. Nadif R, Mintz M, Jedlicka A et al (2005) Association of CAT polymorphisms with catalase activity and exposure to environmental oxidative stimuli. Free Radic Res 39:1345-1350. doi: 10.1080/10715760500306711
13. Ahn J, Nowell S, McCann SE et al (2006) Associations between catalase phenotype and genotype: modification by epidemiologic factors. Cancer Epidemiol Biomarkers Prev 15:1217-1222. doi: 10.1158/1055-9965.EPI-06-0104
14. Bastaki M, Huen K, Manzanillo P et al (2006) Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. Pharmacogenet Genomics 16:279-286. doi: 10.1097/01.fpc.0000199498. 08725.9c
15. Quick SK, Shields PG, Nie J et al (2008) Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev 17:1082-1087. doi: 10.1158/1055-9965.EPI-07-2755
16. Li Y, Ambrosone CB, McCullough MJ et al (2009) Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk. Carcinogenesis 30:777-784. doi: 10.1093/carcin/bgp053
17. Friedenreich CM, Cust AE (2008) Physical activity and breast cancer risk: impact of timing, type and dose of activity and population subgroup effects. Br J Sports Med 42:636-647. doi: 10.1136/bjsm.2006.029132
18. Rundle A (2005) Molecular epidemiology of physical activity and cancer. Cancer Epidemiol Biomarkers Prev 14:227-236
19. Neilson HK, Friedenreich CM, Brockton NT et al (2009) Physical activity and postmenopausal breast cancer: proposed biologic mechanisms and areas for future research. Cancer Epidemiol Biomarkers Prev 18:11-27. doi: 10.1158/1055-9965.EPI-08-0756
20. McTiernan A (2008) Mechanisms linking physical activity with cancer. Nat Rev Cancer 8:205-211. doi: 10.1038/nrc2325
21. Gammon MD, Neugut AI, Santella RM et al (2002) The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer. Breast Cancer Res Treat 74:235-254
22. Zongli X, Taylor J (2009) SNPinfo: Integrating GWAS and candidate gene information into Functional SNP Selection for Genetic Association Studies
23. International HapMap Consortium (2003) The International HapMap project. Nature 426:789-796. doi: 10.1038/nature02168
24. Terry MB, Gammon MD, Zhang FF et al (2004) Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 13:2053-2058
25. Gaudet MM, Bensen JT, Schroeder J et al (2006) Catechol-O- methyltransferase haplotypes and breast cancer among women on Long Island, New York. Breast Cancer Res Treat 99:235-240. doi: 10.1007/s10549-006-9205-0
26. Ahn J, Gammon MD, Santella RM et al (2005) No association between glutathione peroxidase Pro198Leu polymorphism and breast cancer risk. Cancer Epidemiol Biomarkers Prev 14:2459-2461. doi: 10.1158/1055-9965.EPI-05-0459
27. Ahn J, Gammon MD, Santella RM et al (2006) Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk. Carcinogenesis 27:1876-1882. doi: 10.1093/carcin/bgl038
28. Steck SE, Gaudet MM, Britton JA et al (2007) Interactions among GSTM1, GSTT1 and GSTP1 polymorphisms, cruciferous vegetable intake and breast cancer risk. Carcinogenesis 28:1954-1959. doi: 10.1093/carcin/bgm141
29. Gaudet MM, Gammon MD, Santella RM et al (2005) MnSOD Val-9Ala genotype, pro- and anti-oxidant environmental modifiers, and breast cancer among women on Long Island, New York. Cancer Causes Control 16:1225-1234. doi: 10.1007/s10552-005-0375-6
30. Ahn J, Gammon MD, Santella RM et al (2004) Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk. Cancer Res 64:7634-7639. doi: 10.1158/0008-5472.CAN-04-1843
31. Bernstein L, Henderson BE, Hanisch R et al (1994) Physical exercise and reduced risk of breast cancer in young women. J Natl Cancer Inst 86:1403-1408
32. McCullough LE, Eng SM, Bradshaw PT et al (2012) Fat or fit: the joint effects of physical activity, weight gain, and body size on breast cancer risk. Cancer. doi: 10.1002/cncr.27433
33. Ziegler A, Konig I (2006) A statistical approach to genetic epidemiology. Wiley, New York
34. Kleinbaum DG, Klein M (2002) Logistic Regression: A Self-Learning Text, 2nd edn. Springer, New York
35. Greenland S, Brumback B (2002) An overview of relations among causal modelling methods. Int J Epidemiol 31:1030-1037
36. Greenland S (1989) Modeling and variable selection in epidemiologic analysis. Am J Public Health 79:340-349
37. Breslow NE, Day NE (1980) Statistical methods in cancer research. volume i - the analysis of case-control studies. International Agency for Research on Cancer, Lyon
38. Yang XR, Chang-Claude J, Goode EL et al (2011) Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst 103:250-263. doi: 10.1093/jnci/djq526
39. Assmann SF, Hosmer DW, Lemeshow S et al (1996) Confidence intervals for measures of interaction. Epidemiology 7:286-290
40. Rothman K, Greenland S (1998) Modern Epidemiology, 2nd edn. Maple Press, Philadelphia
41. Kanter MM (1994) Free radicals, exercise, and antioxidant supplementation. Int J Sport Nutr 4:205-220
42. Ayres S, Baer J, Subbiah MT (1998) Exercised-induced increase in lipid peroxidation parameters in amenorrheic female athletes. Fertil Steril 69:73-77
43. Clarkson PM, Thompson HS (2000) Antioxidants: what role do they play in physical activity and health? Am J Clin Nutr 72:637S-646S
44. Singh VN (1992) A current perspective on nutrition and exercise. J Nutr 122:760-765
45. Guerra A, Rego C, Castro E et al (2000) LDL peroxidation in adolescent female gymnasts. Rev Port Cardiol 19:1129-1140
46. Guerra A, Rego C, Laires MJ et al (2001) Lipid profile and redox status in high performance rhythmic female teenagers gymnasts. J Sports Med Phys Fitness 41:505-512
47. Vani M, Reddy GP, Reddy GR et al (1990) Glutathione-S-transferase, superoxide dismutase, xanthine oxidase, catalase, glutathione peroxidase and lipid peroxidation in the liver of exercised rats. Biochem Int 21:17-26
48. Evelo CT, Palmen NG, Artur Y et al (1992) Changes in blood glutathione concentrations, and in erythrocyte glutathione reductase and glutathione S-transferase activity after running training and after participation in contests. Eur J Appl Physiol Occup Physiol 64:354-358
49. Miyazaki H, Oh-ishi S, Ookawara T et al (2001) Strenuous endurance training in humans reduces oxidative stress following exhausting exercise. Eur J Appl Physiol 84:1-6
50. Powers SK, Ji LL, Leeuwenburgh C (1999) Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief review. Med Sci Sports Exerc 31:987-997
51. Radak Z, Chung HY, Goto S (2008) Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 44:153-159. doi: 10.1016/j.freeradbiomed.2007.01.029
52. Hoffman-Goetz L, Pervaiz N, Guan J (2009) Voluntary exercise training in mice increases the expression of antioxidant enzymes and decreases the expression of TNF-alpha in intestinal lymphocytes. Brain Behav Immun 23:498-506. doi: 10.1016/j.bbi.2009.01.015
53. Siu PM, Pei XM, Teng BT et al (2011) Habitual exercise increases resistance of lymphocytes to oxidant-induced DNA damage by upregulating expression of antioxidant and DNA repairing enzymes. Exp Physiol 96:889-906. doi: 10.1113/expphysiol.2011.058396
54. Hu X, Ji X, Srivastava SK et al (1997) Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene. Arch Biochem Biophys 345:32-38. doi: 10.1006/abbi.1997.0269
55. Sundberg K, Johansson AS, Stenberg G et al (1998) Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. Carcinogenesis 19:433-436
56. Mao GE, Morris G, Lu QY et al (2004) Glutathione S-transferase P1 Ile105Val polymorphism, cigarette smoking and prostate cancer. Cancer Detect Prev 28:368-374. doi: 10.1016/j.cdp.2004.07.003
57. Schaid DJ, Jacobsen SJ (1999) Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions. Am J Epidemiol 149:706-711