Metabolic profiling reveals that time related physiological changes in mammalian cell perfusion cultures are bioreactor scale independent

Metabolic Engineering

Volumn 19, Issue , 2013, Pages 1-9

  Vernardis, Spyros I ^a,c   Goudar, Chetan T ^b   Klapa, Maria I ^a,d  

^a INSTITUTE OF CHEMICAL ENGINEERING SCIENCES   (Greece)

^b Global Biological Development   (United States)

^c UNIVERSITY OF PATRAS   (Greece)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

GC MS metabolomics; Industrial cell culture engineering; Metabolic network reconstruction; Multivariate statistical analysis; Perfusion cultures

Indexed keywords

INDUSTRIAL CELLS; METABOLIC NETWORK RECONSTRUCTION; METABOLOMICS; MULTIVARIATE STATISTICAL ANALYSIS; PERFUSION CULTURES;

BIOCONVERSION; BIOREACTORS; CELL CULTURE; MANUFACTURE; PHYSIOLOGY;

METABOLISM;

ANALYTIC METHOD; ARTICLE; BIOREACTOR; CELL CULTURE; CELL FUNCTION; CELL METABOLISM; INOCULATION; MAMMALIAN CELL PERFUSION CULTURE; METABOLIC PROFILING; METABOLITE; METABOLOMICS; PHYSIOLOGY; PRIORITY JOURNAL;

GC-MS METABOLOMICS; INDUSTRIAL CELL CULTURE ENGINEERING; METABOLIC NETWORK RECONSTRUCTION; MULTIVARIATE STATISTICAL ANALYSIS; PERFUSION CULTURES;

ANIMALS; BIOREACTORS; CELL LINE; CRICETINAE; METABOLOME; METABOLOMICS; PERFUSION;

MAMMALIA;

EID: 84878820603     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.04.005     Document Type: Article

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