메뉴 건너뛰기




Volumn 18, Issue 2, 2013, Pages 740-747

Role of homeobox genes in the hypothalamic development and energy balance

Author keywords

AgRP; Body weight; Bsx; Food intake; Homeobox gene; Hypothalamus; NPY; Otp; POMC; Review; TTF 1

Indexed keywords

AGOUTI RELATED PROTEIN; AGRP PROTEIN, MOUSE; BSX PROTEIN, MOUSE; DNA BINDING PROTEIN; GHRELIN; HOMEODOMAIN PROTEIN; LEPTIN; NERVE PROTEIN; NEUROPEPTIDE Y; NUCLEAR PROTEIN; OTP PROTEIN, MOUSE; PROOPIOMELANOCORTIN; THYROID NUCLEAR FACTOR 1; TRANSCRIPTION FACTOR; TTF1 PROTEIN, MOUSE;

EID: 84878803471     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/4136     Document Type: Article
Times cited : (16)

References (60)
  • 2
    • 0027977029 scopus 로고
    • Early CNS development: Distal-less related genes and forebrain development
    • DOI 10.1016/0959-4388(94)90028-0
    • E Boncinelli: Early CNS development: Distal-less related genes and forebrain development. Curr Opin Neurobiol 4, 29-36 (1994) (Pubitemid 24059352)
    • (1994) Current Opinion in Neurobiology , vol.4 , Issue.1 , pp. 29-36
    • Boncinelli, E.1
  • 3
    • 0032873404 scopus 로고    scopus 로고
    • Conserved usage of gap and homeotic genes in patterning the CNS
    • DOI 10.1016/S0959-4388(99)00002-1
    • H Reichert, A Simeone: Conserved usage of gap and homeotic genes in patterning the CNS. Curr Opin Neurobiol 9, 589-595 (1999) (Pubitemid 29484384)
    • (1999) Current Opinion in Neurobiology , vol.9 , Issue.5 , pp. 589-595
    • Reichert, H.1    Simeone, A.2
  • 4
    • 0036796883 scopus 로고    scopus 로고
    • Developmental functions of the Distal-less/Dlx homeobox genes
    • G Panganiban, JL Rubenstein: Developmental functions of the Distal-less/Dlx homeobox genes.Development 129, 4371-4386 (2002) (Pubitemid 35203722)
    • (2002) Development , vol.129 , Issue.19 , pp. 4371-4386
    • Panganiban, G.1    Rubenstein, J.L.R.2
  • 6
    • 0021255982 scopus 로고
    • A conserved DNA sequence in homoeotic genes of the Drosophila antennapedia and bithorax complexes
    • W McGinnis, MS Levine, E Hafen, A Kuroiwa, WJ Gehring: A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature 308, 428-433 (1984) (Pubitemid 14130914)
    • (1984) Nature , vol.308 , Issue.5958 , pp. 428-433
    • McGinnis, W.1    Levine, M.S.2    Hafen, E.3
  • 7
    • 0344902715 scopus 로고
    • Structural relationships among genes that control development: Sequence homology between the antennapedia, ultrabithorax, and fushi tarazu loci of Drosophila
    • MP Scott, AJ Weiner: Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila. Proc Natl Acad Sci USA 81, 4115-4119 (1984) (Pubitemid 14054531)
    • (1984) Proceedings of the National Academy of Sciences of the United States of America , vol.81 , Issue.13 , pp. 4115-4119
    • Scott, M.P.1    Weiner, A.J.2
  • 8
    • 0021010766 scopus 로고
    • Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila
    • RL Garber, A Kuroiwa, WJ Gehring: Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila. EMBO J 2, 2027-2036 (1983)
    • (1983) EMBO J , vol.2 , pp. 2027-2036
    • Garber, R.L.1    Kuroiwa, A.2    Gehring, W.J.3
  • 11
    • 0033855367 scopus 로고    scopus 로고
    • Distal-less function during Drosophila appendage and sense organ development
    • DOI 10.1002/1097-0177(200 008)218:4<554::AID-DVDY1 023>3.0.CO;2-#
    • G Panganiban: Distal-less function during Drosophila appendage and sense organ development. Dev Dyn 218, 554-562 (2000) (Pubitemid 30604909)
    • (2000) Developmental Dynamics , vol.218 , Issue.4 , pp. 554-562
    • Panganiban, G.1
  • 12
    • 0024506521 scopus 로고
    • Distal-less encodes a homoeodomain protein required for limb development in Drosophila
    • DOI 10.1038/338432a0
    • SM Cohen, G Brönner, F Küttner, G Jürgens, H Jäckle: Distal-less encodes a homeodomain protein required for limb development in Drosophila. Nature 338, 432-434 (1989) (Pubitemid 19089325)
    • (1989) Nature , vol.338 , Issue.6214 , pp. 432-434
    • Cohen, S.M.1    Bronner, G.2    Kuttner, F.3    Jurgens, G.4    Jackle, H.5
  • 13
    • 0024425434 scopus 로고
    • Proximal-distal pattern formation in Drosophila: Cell autonomous requirement for Distal-less gene activity in limb development
    • SM Cohen, G Jürgens: Proximal-distal pattern formation in Drosophila: cell autonomous requirement for Distal-less gene activity in limb development. EMBO J 8, 2045-2055 (1989) (Pubitemid 19273533)
    • (1989) EMBO Journal , vol.8 , Issue.7 , pp. 2045-2055
    • Cohen, S.M.1    Jurgens, G.2
  • 14
    • 0006289401 scopus 로고    scopus 로고
    • Coexpression of the homeobox genes Distal-less and homothorax determines Drosophila antennal identity
    • PDS Dong, J Chu, G Panganiban: Coexpression of the homeobox genes Distal-less and homothorax determines Drosophila antennal identity. Development 127, 209-216 (2000) (Pubitemid 30087958)
    • (2000) Development , vol.127 , Issue.2 , pp. 209-216
    • Si Dong, P.D.1    Chu, J.2    Panganiban, G.3
  • 15
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
    • DOI 10.1210/er.20.1.68
    • SP Kalra, MG Dube, S Pu, B Xu, TL Horvath, PS Kalra: Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocrine Reviews 20, 68-100 (1999) (Pubitemid 29092036)
    • (1999) Endocrine Reviews , vol.20 , Issue.1 , pp. 68-100
    • Kalra, S.P.1    Dube, M.G.2    Pu, S.3    Xu, B.4    Horvath, T.L.5    Kalra, P.S.6
  • 16
    • 0027991262 scopus 로고
    • Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and drosophila
    • DOI 10.1016/0896-6273(94)90461-8
    • A Simeone, MR D'Apice, V Nigro, J Casanova, F Graziani, D Acampora, V Avantaggiato: Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila. Neuron 13, 83-101 (1994) (Pubitemid 24238416)
    • (1994) Neuron , vol.13 , Issue.1 , pp. 83-101
    • Simeone, A.1    D'Apice, M.R.2    Nigro, V.3    Casanova, J.4    Graziani, F.5    Acampora, D.6    Avantaggiato, V.7
  • 17
    • 0032702290 scopus 로고    scopus 로고
    • Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene
    • D Acampora, MP Postiglione, V Avantaggiato, MD Bonito, FM Vaccarino, J Michaud, A Simeone: Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Gene Dev 13, 2787-2800 (1999)
    • (1999) Gene Dev , vol.13 , pp. 2787-2800
    • Acampora, D.1    Postiglione, M.P.2    Avantaggiato, V.3    Bonito, M.D.4    Vaccarino, F.M.5    Michaud, J.6    Simeone, A.7
  • 18
    • 0034669078 scopus 로고    scopus 로고
    • The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus
    • W Wang, T Lufkin: The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Dev Biol 227, 432-449 (2000)
    • (2000) Dev Biol , vol.227 , pp. 432-449
    • Wang, W.1    Lufkin, T.2
  • 20
    • 38349026620 scopus 로고    scopus 로고
    • Specification of hypothalamic neurons by dual regulation of the homeodomain homeodomain protein Orthopedia
    • J Blechman, N Borodovsky, M Eisenberg, H Nabel- Rosen, J Grimm, G Levkowitz. Specification of hypothalamic neurons by dual regulation of the homeodomain homeodomain protein Orthopedia. Development 134:4417-4426 (2007)
    • (2007) Development , vol.134 , pp. 4417-4426
    • Blechman, J.1    Borodovsky, N.2    Eisenberg, M.3    Nabel-Rosen, H.4    Grimm, J.5    Levkowitz, G.6
  • 22
    • 34247871403 scopus 로고    scopus 로고
    • Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development
    • DOI 10.1016/j.cub.2007.04.003, PII S0960982207012092
    • S Ryu, J Mahler, D Acampora, J Holzschuh, S Erhardt, D Omodei, A Simeone, W Driever. Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development. Curr Biol 17:873-880 (2007) (Pubitemid 46702667)
    • (2007) Current Biology , vol.17 , Issue.10 , pp. 873-880
    • Ryu, S.1    Mahler, J.2    Acampora, D.3    Holzschuh, J.4    Erhardt, S.5    Omodei, D.6    Simeone, A.7    Driever, W.8
  • 24
    • 0033957235 scopus 로고    scopus 로고
    • Vnd/nkx, ind/gsh, and msh/msx: Conserved regulators of dorsoventral neural patterning?
    • DOI 10.1016/S0959-4388(99)00049-5
    • RA Cornell, TV Ohlen: Vnd/nkx, ind/gsh, and msh/msx: conserved regulators of dorsoventral neural patterning? Curr Opin Neurobiol 10, 63-71 (2000) (Pubitemid 30102857)
    • (2000) Current Opinion in Neurobiology , vol.10 , Issue.1 , pp. 63-71
    • Cornell, R.A.1    Von Ohlen, T.2
  • 25
    • 0034665873 scopus 로고    scopus 로고
    • Neural patterning: The role of Nkx genes in the ventral spinal cord
    • AP McMahon: Neural patterning: The role of Nkx genes in the ventral spinal cord. Gene. Dev 14, 2261-2264 (2000)
    • (2000) Gene. Dev , vol.14 , pp. 2261-2264
    • McMahon, A.P.1
  • 26
    • 0029621784 scopus 로고
    • Longitudinal organization of the anterior neural plate and neural tube
    • K Shimamura, DJ Hartigan, S Martinez, L Puelles, JLR Rubenstein: Longitudinal organization of the anterior neural plate and neural tube. Development 121, 3923-3933 (1995) (Pubitemid 26007344)
    • (1995) Development , vol.121 , Issue.12 , pp. 3923-3933
    • Shimamura, K.1    Hartigan, D.J.2    Martinez, S.3    Puelles, L.4    Rubenstein, J.L.R.5
  • 27
    • 0345195959 scopus 로고    scopus 로고
    • Nkx2-9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS
    • DOI 10.1016/S0925-4773(98)00035-5, PII S0925477398000355
    • O Pabst, H Herbrand, HH Arnold: Nkx2-9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS. Mec Dev 73, 85-93 (1998) (Pubitemid 28218545)
    • (1998) Mechanisms of Development , vol.73 , Issue.1 , pp. 85-93
    • Pabst, O.1    Herbrand, H.2    Arnold, H.-H.3
  • 28
    • 0032033034 scopus 로고    scopus 로고
    • Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development
    • DOI 10.1016/S0925-4773(98)00018-5, PII S0925477398000185
    • M Qiu, K Shimamura, L Sussel, S Chen, JLR Rubenstein: Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mech Dev 72, 77-88 (1998) (Pubitemid 28186708)
    • (1998) Mechanisms of Development , vol.72 , Issue.1-2 , pp. 77-88
    • Qiu, M.1    Shimamura, K.2    Sussel, L.3    Chen, S.4    Rubenstein, J.L.R.5
  • 30
    • 0029075802 scopus 로고
    • Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain
    • KA Barth, SW Wilson: Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development 121, 1755-1768 (1995)
    • (1995) Development , vol.121 , pp. 1755-1768
    • Barth, K.A.1    Wilson, S.W.2
  • 31
    • 0030796030 scopus 로고    scopus 로고
    • Inductive interactions direct early regionalization of the mouse forebrain
    • K Shimamura, JLR Rubenstein: Inductive interactions direct early regionalization of the mouse forebrain. Development 124, 2709-2718 (1997) (Pubitemid 27354817)
    • (1997) Development , vol.124 , Issue.14 , pp. 2709-2718
    • Shimamura, K.1    Rubenstein, J.L.R.2
  • 32
    • 0030057596 scopus 로고    scopus 로고
    • The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
    • S Kimura, Y Hara, T Pineau, P Fernandez-Salguero, CH Fox, JM Ward, FJ Gonzalez: The T/ebp null mouse: thyroidspecific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Gene Dev 10, 60-69 (1996) (Pubitemid 26025299)
    • (1996) Genes and Development , vol.10 , Issue.1 , pp. 60-69
    • Kimura, S.1    Hara, Y.2    Pineau, T.3    Fernandez-Salguero, P.4    Fox, C.H.5    Ward, J.M.6    Gonzalez, F.J.7
  • 33
    • 0033560895 scopus 로고    scopus 로고
    • Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
    • DOI 10.1038/19315
    • J Briscoe, L Sussel, P Serup, D Hartigan-O'Connor, TM Jessell, JLR Rubenstein, J Ericson: Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signaling. Nature 398, 622-627 (1999) (Pubitemid 29183690)
    • (1999) Nature , vol.398 , Issue.6728 , pp. 622-627
    • Briscoe, J.1    Sussel, L.2    Serup, P.3    Hartigan-O'Connor, D.4    Jessell, T.M.5    Rubenstein, J.L.R.6    Ericson, J.7
  • 34
    • 0041827087 scopus 로고    scopus 로고
    • Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain
    • DOI 10.1242/dev.00641
    • A Pattyn, A Vallstedt, JM Dias, M Sander, J Ericson: Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Development 130, 4149-4159 (2003) (Pubitemid 37063431)
    • (2003) Development , vol.130 , Issue.17 , pp. 4149-4159
    • Pattyn, A.1    Vallstedt, A.2    Dias, J.M.3    Sander, M.4    Ericson, J.5
  • 35
    • 0024425390 scopus 로고
    • A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter
    • D Civitareale, R Lonigro, AJ Sinclair, RD Lauro: A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter. EMBO J 8, 2537- 2542 (1989) (Pubitemid 19273336)
    • (1989) EMBO Journal , vol.8 , Issue.9 , pp. 2537-2542
    • Civitareale, D.1    Lonigro, R.2    Sinclair, A.J.3    Di Lauro, R.4
  • 36
    • 0026340586 scopus 로고
    • The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain
    • D Lazzaro, M Price, M De Felice, R Di Lauro: The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 113, 1093-1104 (1991)
    • (1991) Development , vol.113 , pp. 1093-1104
    • Lazzaro, D.1    Price, M.2    De Felice, M.3    Di Lauro, R.4
  • 37
    • 0035944549 scopus 로고    scopus 로고
    • Immunohistochemical analyses of thyroid-specific enhancer-binding protein in the fetal and adult rat hypothalami and pituitary glands
    • DOI 10.1016/S0165-3806(01)00226-7, PII S0165380601002267
    • K Nakamura, S Kimura, M Yamazaki, A Kawaguchi, K Inoue, T Sakai: Immunohistochemical analyses of thyroidspecific enhancer-binding protein in the fetal and adult rat hypothalami and pituitary glands. Dev Brain Res 130, 159-166 (2001) (Pubitemid 33000080)
    • (2001) Developmental Brain Research , vol.130 , Issue.2 , pp. 159-166
    • Nakamura, K.1    Kimura, S.2    Yamazaki, M.3    Kawaguchi, A.4    Inoue, K.5    Sakai, T.6
  • 38
    • 0033042451 scopus 로고    scopus 로고
    • Sequence and developmental expression of amphioxus AmphiNk2-1: Insights into the evolutionary origin of the vertebrate thyroid gland and forebrain
    • DOI 10.1007/s004270050250
    • TV Venkatesh, ND Holland, LZ Holland, MT Su, R Bodmer: Sequence and developmental expression of amphioxus AmphiNk2-1: insights into the evolutionary origin of the vertebrate thyroid gland and forebrain. Dev Genes Evol 209, 254-259 (1999) (Pubitemid 29142244)
    • (1999) Development Genes and Evolution , vol.209 , Issue.4 , pp. 254-259
    • Venkatesh, T.V.1    Holland, N.D.2    Holland, L.Z.3    Su, M.-T.4    Bodmer, R.5
  • 39
    • 0034062021 scopus 로고    scopus 로고
    • Overlapping expression of amphioxus homologs of the thyroid transcription factor-1 gene and thyroid peroxidase gene in the endostyle: Insight into evolution of the thyroid gland
    • DOI 10.1007/s004270050309
    • M Ogasawara: Overlapping expression of amphioxus homologs of the thyroid transcription factor-1 gene and thyroid peroxidase gene in the endostyle: insight into evolution of the thyroid gland. Dev Genes Evol 210, 231-242 (2000) (Pubitemid 30234960)
    • (2000) Development Genes and Evolution , vol.210 , Issue.5 , pp. 231-242
    • Ogasawara, M.1
  • 40
    • 0034963388 scopus 로고    scopus 로고
    • Expression of Thyroid transcription factor-1 (TTF-1) gene in the ventral forebrain and endostyle of the agnathan vertebrate, Lampetra japonica
    • DOI 10.1002/gene.1032
    • MOgasawara, Y Shigetani, S Suzuki, S Kuratani, N Satoh: Expression of Thyroid transcription factor-1 (TTF-1) gene in the ventral forebrain and endostyle of the agnathan vertebrate, Lampetra japonica. Genesis 30, 51-58 (2001) (Pubitemid 32613650)
    • (2001) Genesis , vol.30 , Issue.2 , pp. 51-58
    • Ogasawara, M.1    Shigetani, Y.2    Suzuki, S.3    Kuratani, S.4    Satoh, S.K.N.5
  • 41
    • 20744436200 scopus 로고    scopus 로고
    • Comparative expression analysis of transcription factor genes in the endostyle of invertebrate chordates
    • DOI 10.1002/dvdy.20401
    • J Hiruta, F Mazet, K Yasui, P Zhang, M Ogasawara: Comparative expression analysis of transcription factor genes in the endostyle of invertebrate chordates. Dev Dyn 233, 1031-1037 (2005) (Pubitemid 40853480)
    • (2005) Developmental Dynamics , vol.233 , Issue.3 , pp. 1031-1037
    • Hiruta, J.1    Mazet, F.2    Yasui, K.3    Zhang, P.4    Ogasawara, M.5
  • 42
    • 38049088052 scopus 로고    scopus 로고
    • Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution
    • WMR van den Akker, A Brox, L Puelles, AJ Durston, L Medina: Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution. J Comp Neuro 506, 211-223 (2008)
    • (2008) J Comp Neuro , vol.506 , pp. 211-223
    • Van Den Akker, W.1    Brox, A.2    Puelles, L.3    Durston, A.J.4    Medina, L.5
  • 43
    • 0036340008 scopus 로고    scopus 로고
    • Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections
    • O Marín, J Baker, L Puelles, JLR Rubenstein: Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections. Development 129, 761-773 (2002) (Pubitemid 34863836)
    • (2002) Development , vol.129 , Issue.3 , pp. 761-773
    • Marin, O.1    Baker, J.2    Puelles, L.3    Rubenstein, J.L.R.4
  • 46
    • 0345096617 scopus 로고    scopus 로고
    • Bsx, an evolutionary conserved Brain Specific homeoboX gene expressed in the septum, epiphysis, mammillary bodies and arcuate nucleus
    • DOI 10.1016/S1567-133X(03)00151-0, PII S1567133X03001510
    • M Cremona, E Colombo, M Andreazzoli, G Cossu, V Broccoli: Bsx, an evolutionary conserved Brain Specific homeoboX gene expressed in the septum, epiphysis, mammillary bodies and arcuate nucleus. Gene Expr Patterns 4, 47-51 (2004) (Pubitemid 37498292)
    • (2004) Gene Expression Patterns , vol.4 , Issue.1 , pp. 47-51
    • Cremona, M.1    Colombo, E.2    Andreazzoli, M.3    Cossu, G.4    Broccoli, V.5
  • 47
    • 0027466643 scopus 로고
    • A new Drosophila homeobox gene, bsh, is expressed in a subset of brain cells during embryogenesis
    • B Jones,WMcGinnis: A new Drosophila homeobox gene, bsh, is expressed in a subset of brain cells during embryogenesis. Development 117, 793-806 (1993) (Pubitemid 23103185)
    • (1993) Development , vol.117 , Issue.2 , pp. 793-806
    • Jones, B.1    McGinnis, W.2
  • 48
    • 34249707945 scopus 로고    scopus 로고
    • A role for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior
    • DOI 10.1016/j.cmet.2007.05.007, PII S1550413107001349
    • MSakkou, PWiedmer, K Anlag, A Hamm, E Seuntjens, L Ettwiller, MH Tschöp, M Treier: A role for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior. Cell Metabo 5, 450-463 (2007) (Pubitemid 46825499)
    • (2007) Cell Metabolism , vol.5 , Issue.6 , pp. 450-463
    • Sakkou, M.1    Wiedmer, P.2    Anlag, K.3    Hamm, A.4    Seuntjens, E.5    Ettwiller, L.6    Tschop, MatthiasH.7    Treier, M.8
  • 50
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • DOI 10.1038/nn1455
    • RD Cone: Anatomy and regulation of the central melanocortin system. Nat Neurosci 8, 571-578 (2005) (Pubitemid 40594196)
    • (2005) Nature Neuroscience , vol.8 , Issue.5 , pp. 571-578
    • Cone, R.D.1
  • 51
    • 33748931457 scopus 로고    scopus 로고
    • Central nervous system control of food intake and body weight
    • DOI 10.1038/nature05026, PII NATURE05026
    • GJ Morton, DE Cummings, DG Baskin, GS Barsh, MW Schwartz: Central nervous system control of food intake and body weight. Nature 443, 289-295 (2006) (Pubitemid 44435142)
    • (2006) Nature , vol.443 , Issue.7109 , pp. 289-295
    • Morton, G.J.1    Cummings, D.E.2    Baskin, D.G.3    Barsh, G.S.4    Schwartz, M.W.5
  • 52
    • 34250612718 scopus 로고    scopus 로고
    • The leptin melanocortin pathway and the control of body weight: Lessons from human and murine genetics
    • DOI 10.1111/j.1467-789X.2007.00378.x
    • A Oswal, GSH Yeo: The leptin melanocortin pathway and the control of body weight: lessons from human and murine genetics. Obes Rev. 8, 293-306 (2007) (Pubitemid 46944499)
    • (2007) Obesity Reviews , vol.8 , Issue.4 , pp. 293-306
    • Oswal, A.1    Yeo, G.S.H.2
  • 53
    • 50249120768 scopus 로고    scopus 로고
    • Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
    • Q Tong, CP Ye, JE Jones, JK Elmquist, BB Lowell: Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat Neurosci 11, 998- 1000 (2008)
    • (2008) Nat Neurosci , vol.11 , pp. 998-1000
    • Tong, Q.1    Ye, C.P.2    Jones, J.E.3    Elmquist, J.K.4    Lowell, B.B.5
  • 54
    • 0029946644 scopus 로고    scopus 로고
    • Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide y
    • JC Erickson, KE Clegg, RD Palmiter: Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381, 415-421 (1996)
    • (1996) Nature , vol.381 , pp. 415-421
    • Erickson, J.C.1    Clegg, K.E.2    Palmiter, R.D.3
  • 56
    • 27344431720 scopus 로고    scopus 로고
    • NPY/AgRP neurons are essentials for feeding in adult mice but can be ablated in neonates
    • DOI 10.1126/science.1115524
    • S Luquet, FA Perez, TS Hnasko, RD Palmiter: NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 310, 683-685 (2005) (Pubitemid 41528162)
    • (2005) Science , vol.310 , Issue.5748 , pp. 683-685
    • Luquet, S.1    Perez, F.A.2    Hnasko, T.S.3    Palmiter, R.D.4
  • 58
    • 0032863468 scopus 로고    scopus 로고
    • Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
    • DOI 10.1038/12506
    • L Yaswen, N Diehl, MB Brennan, U Hochgeschwender : Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat Med 5, 1066-1070 (1998) (Pubitemid 29439581)
    • (1999) Nature Medicine , vol.5 , Issue.9 , pp. 1066-1070
    • Yaswen, L.1    Diehl, N.2    Brennan, M.B.3    Hochgeschwender, U.4
  • 59
    • 0031721271 scopus 로고    scopus 로고
    • Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT(2C) receptor gene
    • DOI 10.1038/2647
    • K Nonogaki, A Strack, MF Dallman, LH Tecott: Leptinindependent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat Med 4, 1152- 1156 (1998) (Pubitemid 28468828)
    • (1998) Nature Medicine , vol.4 , Issue.10 , pp. 1152-1156
    • Nonogaki, K.1    Strack, A.M.2    Dallman, M.F.3    Tecott, L.H.4
  • 60
    • 0033060430 scopus 로고    scopus 로고
    • Obesity: Autonomic circuits versus feeding
    • DOI 10.1038/10464
    • K Nonogaki: Obesity: Autonomic circuits versus feeding. Nat Med 5, 742-743 (1999) (Pubitemid 29318606)
    • (1999) Nature Medicine , vol.5 , Issue.7 , pp. 742-743
    • Nonogaki, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.