A peek inside the neurosecretory brain through Orthopedia lenses

Developmental Dynamics

Volumn 237, Issue 9, 2008, Pages 2295-2303

  Del Giacco, Luca ^a   Pistocchi, Anna ^a   Cotelli, Franco ^a   Fortunato, Antonio Emidio ^b,c   Sordino, Paolo ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c STAZIONE ZOOLOGICA ANTON DOHRN   (Italy)

Author keywords

Development; Dopamine, DA; Hypothalamic; Hypothalamus; Neurohormones; Nuclei; Orthopedia; Otp

Indexed keywords

HOMEODOMAIN PROTEIN; ORTHOPEDIA PROTEIN; PEPTIDE; UNCLASSIFIED DRUG;

CELL NUCLEUS INCLUSION BODY; DIENCEPHALON; DOPAMINERGIC NERVE CELL; EVOLUTION; FISH; HORMONE RELEASE; HYPOTHALAMUS; MAMMAL; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE GROWTH; NEUROENDOCRINE SYSTEM; NEUROPATHY; NEUROSECRETION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; VERTEBRATE;

ANIMALS; BRAIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NEUROSECRETORY SYSTEMS;

MAMMALIA; VERTEBRATA;

EID: 51549118471     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21668     Document Type: Review

References (79)

1. Acampora D, Postiglione MP, Avantaggiato V, Di Bonito M, Vaccarino FM, Michaud J, Simeone A. 1999. Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Genes Dev 13:2787-2800.
2. Acampora D, Postiglione MP, Avantaggiato V, Di Bonito M, Simeone A. 2000. The role of Otx and Otp genes in brain development [review]. Int J Dev Biol 44: 669-677.
3. Acher R, Chauvet J, Rouillé Y. 1997. Adaptive evolution of water homeostasis regulation in amphibians: vasotocin and hydrins [review]. Biol Cell 89:283-291.
4. Alvarez-Bolado G, Rosenfeld MG, Swanson LW. 1995. Model of forebrain regionalization based on spatiotemporal patterns of POU-III homeobox gene expression, birthdates, and morphological features. J Comp Neurol 355:237-295.
5. Amore G, Yavrouian RG, Peterson KJ Ransick A, McClay DR, Davidson EH. 2003. Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks. Dev Biol 261:55-81.
6. Amores A, Force A, Yan YL, Joly L, Amemiya C, Fritz A, Ho RK, Langeland J, Prince V, Wang YL, Westerfield M, Ekker M, Postlethwait JH. 1998. Zebrafish hox clusters and vertebrate genome evolution. Science 282:1711-1714.
7. Balment RJ, Lu W, Weybourne E, Warne JM. 2006. Arginine vasotocin a key hormone in fish physiology and behaviour: a review with insights from mammalian models. Gen Comp Endocrinol 147:9-16.
8. Bardet SM, Martinez-de-la-Torre M, Northcutt RG, Rubenstein JL, Puelles L. 2008. Conserved pattern of OTP-positive cells in the paraventricular nucleus and other hypothalamic sites of tetrapods. Brain Res Bull 75:231-235.
9. Blechman J, Borodovsky N, Eisenberg M, Nabel-Rosen H, Grimm J, Levkowitz G. 2007. Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia. Development 134:4417-4426.
10. Cavalieri V, Spinelli G, Di Bernardo M. 2003. Impairing Otp homeodomain function in oral ectoderm cells affects skeletogenesis in sea urchin embryos. Dev Biol 262:107-118.
11. Cavalieri V, Di Bernardo M, Spinelli G. 2007. Regulatory sequences driving expression of the sea urchin Otp homeobox gene in oral ectoderm cells. Gene Expr Patterns 7:124-130.
12. Choksi SP, Southall TD, Bossing T, Edoff K, de Wit E, Fischer BE, van Steensel B, Micklem G, Brand AH. 2006. Prospero acts as a binary switch between self-renewal and differentiation in drosophila neural stem cells. Dev Cell 11:775-789.
13. Clemens S, Rye D, Hochman S. 2006. Restless legs syndrome: revisiting the dopamine hypothesis the spinal cord perspective. Neurology 67:125-130.
14. Del Giacco L, Sordino P, Pistocchi A, Andreakis N, Tarallo R, Di Benedetto B, Cotelli F. 2006. Differential regulation of the zebrafish orthopedia 1 gene during fate determination of diencephalic neurons. BMC Dev Biol 30:6-50.
15. Di Bernardo M, Castagnetti S, Bellomonte D, Oliveri P, Melfi R, Palla F, Spinelli G. 1999. Spatially restricted expression of PlOtp, a Paracentrotus lividus Orthopedia-related homeobox gene, is correlated with oral ectodermal patterning and skeletal morphogenesis in late-cleavage sea urchin embryos. Development 126: 2171-2179.
16. Dyer MA. 2003. Regulation of proliferation, cell fate specification and differentiation by the homeodomain proteins Prox1, Six3, and Chx10 in the developing retina. Cell Cycle 2:350-357.
17. Eaton JL, Glasgow E. 2007. Zebrafish orthopedia (otp) is required for isotocin cell development. Dev Genes Evol 217:149-158.
18. Eaton JL, Holmqvist B, Glasgow E. 2008. Ontogeny of vasotocin-expressing cells in zebrafish: selective requirement for the transcriptional regulators orthopedia and single-minded 1 in the preoptic area. Dev Dyn 237:995-1005.
19. Ferguson JN, Young LJ, Insel TR. 2002. The neuroendocrine basis of social recognition [review]. Front Neuroendocrinol 23:200-224.
20. Force A, Lynch M, Pickett FB, Amores A, Yan YL, Postlethwait JH. 1999. Preservation of duplicate genes by complementary, degenerative mutations. Genetics 151:1531-1545.
21. Gainer H, Wray S. 1992. Oxytocin and vasopressin. From genes to peptides [review]. Ann N Y Acad Sci 652:14-28.
22. Goodson JL, Bass A. 2001. Social behaviour functions and related anatomical characteristics of vasotocin/vasopressin systems in vertebrates. Brain Res Rev 35:246-265.
23. Guillemin R. 2004. Neuroendocrine basis of human disease. Ann N Y Acad Sci 1038:131-137.
24. Guo S, Wilson SW, Cooke S, Chitnis AB, Driever W, Rosenthal A. 1999. Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons. Dev Biol 208:473-487.
25. Hatta K, Kimmel CB, Ho RK, Walker C. 1991. The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature 350:339-341.
26. Hatta K, Puschel A, Kimmel CB. 1994. Midline signaling in the primordium of the zebrafish anterior central nervous system. Proc Natl Acad Sci U S A 91: 2061-2065.
27. Hollander E, Novotny S, Hanratty M, Yaffe R, DeCaria CM, Aronowitz BR, Mosovich S. 2003. Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger's disorders. Neuropsychopharmacology 28:193-198.
28. Holzschuh J, Ryu S, Aberger F, Driever W. 2001. Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. Mech Dev 101:237-243.
29. Insel TR, Young L, Wang Z. 1997. Central oxytocin and reproductive behaviours [review]. Rev Reprod 2:28-37.
30. Insel TR, O'Brien DJ, Leckman JF. 1999. Oxytocin, vasopressin, and autism: is there a connection [review]? Biol Psychiatry 45:145-157.
31. Krauss S, Concordet JP, Ingham PW. 1993. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75: 1431-1444.
32. Kuang C, Xiao Y, Yang L, Chen Q, Wang Z, Conway SJ, Chen Y. 2006. Intragenic deletion of Tgif causes defects in brain development. Hum Mol Genet 15:3508-3519.
33. Joly JS, Osório J, Alunni A, Auger H, Kano S, Rétaux S. 2007. Windows of the brain: towards a developmental biology of circumventricular and other neurohemal organs. Semin Cell Dev Biol 18:512-524.
34. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM. Riddle MA, McSwiggan-Hardin M, McDougle CJ, et al. 1994. Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. Arch Gen Psychiatry 51:782-792.
35. Levkowitz G, Zeller J, Sirotkin HI, French D, Schilbach S, Hashimoto H, Hibi M, Talbot WS, Rosenthal A. 2003. Zinc finger protein too few controls the development of monoaminergic neurons. Nat Neurosci 6:28-33.
36. Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M. 2003. Anteroposterior patterning in Hemichordates and the origins of the chordate nervous system. Cell 113:853-865.
37. Ma PM. 1994a. Catecholaminergic systems in the zebrafish. I. Number, morphology, and histochemical characteristics of neurons in the locus coeruleus. J Comp Neurol 344:242-255.
38. Ma PM. 1994b. Catecholaminergic systems in the zebrafish. II. Projection pathways and pattern of termination of the locus coeruleus. J Comp Neurol 344:256-269.
39. Ma PM. 1997. Catecholaminergic systems in the zebrafish. III. Organization and projection pattern of medullary dopaminergic and noradrenergic neurons. J Comp Neurol 381:411-427.
40. Ma PM. 2003. Catecholaminergic Systems in the Zebrafish. IV. Organization and projection pattern of dopaminergic neurons in the diencephalon. J Comp Neurol 460:13-37.
41. Ma PM, Lopez M. 2003. Consistency in the number of dopaminergic paraventricular organ-accompanying neurons in the posterior tuberculum of the zebrafish brain. Brain Res 967:267-272.
42. Manni L, Agnoletto A, Zaniolo G, Burighel P. 2005. Stomodeal and neurohypophysial placodes in Ciona intestinalis: insights into the origin of the pituitary gland. J Exp Zool B Mol Dev Evol 304: 324-339.
43. Mason ST. 1984. Catecholamines and behavior. Cambridge: Cambridge University Press.
44. Michaud JL. 2001. The developmental program of the hypothalamus and its disorders [review]. Clin Genet 60:255-263.
45. Michaud JL, Rosenquist T, May NR, Fan CM. 1998. Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. Genes Dev 12: 3264-3275.
46. Michaud JL, DeRossi C, May NR, Holdener BC, Fan CM. 2000. ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus. Mech Dev 90:253-261.
47. Nederbragt AJ, te Welscher P, van den Driesche S, van Loon AE, Dictus WJ. 2002. Novel and conserved roles for orthodenticle/otx and orthopedia/otp orthologs in the gastropod mollusc Patella vulgata. Dev Genes Evol 212:330-337.
48. Philibert RA, Madan A. 2007. Role of MED12 in transcription and human behavior [review]. Pharmacogenomics 8:909-916.
49. Pistocchi A, Gaudenzi G, Carra S, Bresciani E, Del Giacco L, Cotelli F. 2008. Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development. BMC Dev Biol 10:8-27.
50. Postlethwait JH, Woods IG, Ngo-Hazelett P, Yan YL, Kelly PD, Chu F, Huang H, Hill-Force A, Talbot WS. 2000. Zebrafish comparative genomics and the origins of vertebrate chromosomes. Genome Res 10:1890-1902.
51. Puelles L, Rubenstein JL. 1993. Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization [review]. Trends Neurosci 16:472-479.
52. Puelles L, Rubenstein JL. 2003. Forebrain gene expression domains and the evolving prosomeric model. Trends Neurosci 26:469-476.
53. Purba JS, Hoogendijk WJ, Hofman MA, Swaab DF. 1996. Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression. Arch Gen Psychiatry 53:137-143.
54. Rebagliati MR, Toyama R, Haffter P, Dawid IB. 1998. cyclops encodes a nodal-related factor involved in midline signaling. Proc Natl Acad Sci U S A 95:9932-9937.
55. Reifers F, Bohli H, Walsh EC, Crossley PH, Stainier DY, Brand M. 1998. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125:2381-2395.
56. Rink E, Wullimann MF. 2001. The teleostean (zebrafish) dopaminergic system ascending to the subpallium (striatum) is located in the basal diencephalon (posterior tuberculum). Brain Res 889: 316-330.
57. Rink E, Wullimann MF. 2002. Development of the catecholaminergic system in the early zebrafish brain: an immunohistochemical study. Brain Res Dev Brain Res 137:89-100.
58. Rubenstein JLR, Martinez S, Shimamura K, Puelles L. 1994. The embryonic vertebrate forebrain: the prosomeric model. Science 266:578-580.
59. Ryu S, Mahler J, Acampora D, Holzschuh J, Erhardt S, Omodei D, Simeone A, Driever W. 2007. Orthopedia homeodo-main protein is essential for diencephalic dopaminergic neuron development. Curr Biol 17:873-880.
60. Sampath K, Rubenstein AL, Cheng AM, Liang JO, Fekany K, Sonica-Krezel L, Korzh V, Halpern ME, Wright CV. 1998. Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signaling. Nature 395:185-189.
61. Sandyk R, Iacono RP, Bamford CR. 1987. The hypothalamus in Tourette's syndrome. Int J Neurosci 35:99-103.
62. Sarnat HB, Flores-Sarnat L. 2001. Neuropathology research strategies in holoprosencephaly [review]. J Child Neurol 16:918-931.
63. Schauerte HE, van Eeden FJ, Fricke C, Odenthal J, Strahle U, Haffter P. 1998. Sonic hedgehog is not required for the induction of medial floorplate cells in the zebrafish. Development 125:2983-2993.
64. Sekimizu K, Nishioka N, Sasaki H, Takeda H, Karlstrom RO, Kawakami A. 2004. The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling. Development 131:2521-2532.
65. Shimoda M, Yoshimoto T, Kono T, Ikai I, Kubo H. 2006. A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma. Clin Cancer Res 12:6005-6011.
66. Simeone A, D'Apice MR, Nigro V, Casanova J, Graziani F, Acampora D, Avantaggiato V. 1994. Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila. Neuron 13:83-101.
67. Swaab DF. 1995. Development of the human hypothalamus. Neurochem Res 20: 509-519.
68. Swanson LW, Sawchenko PE. 1983. Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Annu Rev Neurosci 6:269-324.
69. Tessmar-Raible K, Raible F, Christodoulou F, Guy K, Rembold M, Hausen H, Arendt D. 2007. Conserved sensory-neurosecretory cell types in annelid and fish forebrain: insights into hypothalamus evolution. Cell 129:1389-1400.
70. Umesono Y, Watanabe K, Agata K. 1997. A planarian orthopedia homolog is specifically expressed in the branch region of both the mature and regenerating brain. Dev Growth Differ 39:723-727.
71. Umesono Y, Watanabe K, Agata K. 1999. Distinct structural domains in the planarian brain defined by the expression of evolutionarily conserved homeobox genes. Dev Genes Evol 209:31-39.
72. Venkatesh B, Brenner S. 1995. Structure and organization of the isotocin and vasotocin genes from teleosts. Adv Exp Med Biol 395:629-638.
73. Wang W, Lufkin T. 2000. The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Dev Biol 227:432-449.
74. Wang X, Yang N, Uno E, Roeder RG, Guo S. 2006. A subunit of the mediator complex regulates vertebrate neuronal development. Proc Natl Acad Sci U S A 103:17284-17289.
75. Wittbrodt J, Meyer A, Schartl M. 1998. More genes in fish? Bioessays 20:511-515.
76. Wolff C, Roy S, Lewis KE, Schauerte H, Joerg-Rauch G, Kirn A, Weiler C, Geisler R, Haffter P, Ingham PW. 2004. iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo. Genes Dev 18:1565-1576.
77. Wotton D, Lo RS, Swaby LA, Massague J. 1999. Multiple modes of repression by the Smad transcriptional corepressor TGIF. J Biol Chem 274:37105-37110.
78. Young WS III, Iacangelo A, Luo XZ, King C, Duncan K, Ginns EI. 1999. Transgenic expression of green fluorescent protein in mouse oxytocin neurones. J Neuroendocrinol 11:935-939.
79. Zhou N, Wilson KA, Andrews ME, Kauffman JS, Raff RA. 2003. Evolution of OTP-independent larval skeleton patterning in the direct developing sea urchin, Heliocidaris erythrogramma. J Exp Zoolog B Mol Dev Evol 300:58-71.