Frailty in Old Age Is Associated with Decreased Interleukin-12/23 Production in Response to Toll-Like Receptor Ligation

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Compté, Nathalie ^a   Zouaoui Boudjeltia, Karim ^a   Vanhaeverbeek, Michel ^a   De Breucker, Sandra ^b   Tassignon, Joel ^c   Trelcat, Anne ^c   Pepersack, Thierry ^b   Goriely, Stanislas ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b ERASME HOSPITAL   (Belgium)

^c ImmuneHealth   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12P70; INTERLEUKIN 23; TOLL LIKE RECEPTOR; IMIDAZOLE DERIVATIVE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; LIGAND; LIPOPOLYSACCHARIDE; RESIQUIMOD;

AGE; AGED; ARTICLE; BLOOD SAMPLING; CELL SUBPOPULATION; COMORBIDITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISABILITY; FEMALE; FRAILTY; HUMAN; HUMAN CELL; INFECTION SENSITIVITY; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; NUTRITIONAL STATUS; TELOMERE HOMEOSTASIS; ADULT; AGONISTS; BIOSYNTHESIS; CELL CULTURE; FRAIL ELDERLY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; SIGNAL TRANSDUCTION; VERY ELDERLY; YOUNG ADULT;

BACTERIA (MICROORGANISMS); CYTOMEGALOVIRUS;

ADULT; AGED; AGED, 80 AND OVER; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; FRAIL ELDERLY; HUMANS; IMIDAZOLES; IMMUNITY, INNATE; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-12; INTERLEUKIN-23; LIGANDS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; NUTRITIONAL STATUS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; YOUNG ADULT;

EID: 84878758157     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065325     Document Type: Article

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