-
1
-
-
77949335521
-
The worldwide societal costs of dementia: Estimates for 2009
-
Wimo A, Winblad B, Jonsson L (2010) The worldwide societal costs of dementia: Estimates for 2009. Alzheimers Dement 6, 98-103.
-
(2010)
Alzheimers Dement
, vol.6
, pp. 98-103
-
-
Wimo, A.1
Winblad, B.2
Jonsson, L.3
-
2
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297, 353-356. (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
3
-
-
80052501210
-
Resolving controversies on the path to Alzheimer's therapeutics
-
Selkoe DJ (2011) Resolving controversies on the path to Alzheimer's therapeutics. Nat Med 17, 1060-1065.
-
(2011)
Nat Med
, vol.17
, pp. 1060-1065
-
-
Selkoe, D.J.1
-
4
-
-
78149488153
-
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis
-
Pimplikar SW, Nixon RA, Robakis NK, Shen J, Tsai LH (2010) Amyloid-independent mechanisms in Alzheimer's disease pathogenesis. J Neurosci 30, 14946-14954.
-
(2010)
J Neurosci
, vol.30
, pp. 14946-14954
-
-
Pimplikar, S.W.1
Nixon, R.A.2
Robakis, N.K.3
Shen, J.4
Tsai, L.H.5
-
5
-
-
35848931249
-
Erratum: Increased autophagic degradation of mitochondria in Alzheimer disease (Autophagy)
-
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G (2007) Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy 3, 614-615. (Pubitemid 350060061)
-
(2007)
Autophagy
, vol.3
, Issue.6
, pp. 614-615
-
-
Moreira, P.I.1
Siedlak, S.L.2
Wang, X.3
Santos, M.S.4
Oliveira, C.R.5
Tabaton, M.6
Nunomura, A.7
Szweda, L.I.8
Aliev, G.9
Smith, M.A.10
Zhu, X.11
Perry, G.12
-
6
-
-
34547889114
-
Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin
-
DOI 10.1073/pnas.0701267104
-
Fiala M, Liu PT, Espinosa-Jeffrey A, Rosenthal MJ, Bernard G, Ringman JM, Sayre J, Zhang L, Zaghi J, Dejbakhsh S, Chiang B, Hui J, Mahanian M, Baghaee A, Hong P, Cashman J (2007) Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Proc Natl Acad Sci U S A 104, 12849-12854. (Pubitemid 47255243)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.31
, pp. 12849-12854
-
-
Fiala, M.1
Liu, P.T.2
Espinosa-Jeffrey, A.3
Rosenthal, M.J.4
Bernard, G.5
Ringman, J.M.6
Sayre, J.7
Zhang, L.8
Zaghi, J.9
Dejbakhsh, S.10
Chiang, B.11
Hui, J.12
Mahanian, M.13
Baghaee, A.14
Hong, P.15
Cashman, J.16
-
7
-
-
79959652671
-
MGAT3 mRNA: Abiomarker for prognosis and therapy of Alzheimer's disease by vitamin D and curcuminoids
-
Fiala M, Mahanian M, Rosenthal M, Mizwicki MT, Tse E, Cho T, Sayre J, Weitzman R, Porter V (2011) MGAT3 mRNA: Abiomarker for prognosis and therapy of Alzheimer's disease by vitamin D and curcuminoids. J Alzheimers Dis 25, 135-144.
-
(2011)
J Alzheimers Dis
, vol.25
, pp. 135-144
-
-
Fiala, M.1
Mahanian, M.2
Rosenthal, M.3
Mizwicki, M.T.4
Tse, E.5
Cho, T.6
Sayre, J.7
Weitzman, R.8
Porter, V.9
-
8
-
-
67349091252
-
Immune blood biomarkers of Alzheimer disease patients
-
Avagyan H, Goldenson B, Tse E, Masoumi A, Porter V, Wiedau-Pazos M, Sayre J, Ong R, Mahanian M, Koo P, Bae S, Micic M, Liu PT, Rosenthal MJ, Fiala M (2009) Immune blood biomarkers of Alzheimer disease patients. J Neuroimmunol 210, 67-72.
-
(2009)
J Neuroimmunol
, vol.210
, pp. 67-72
-
-
Avagyan, H.1
Goldenson, B.2
Tse, E.3
Masoumi, A.4
Porter, V.5
Wiedau-Pazos, M.6
Sayre, J.7
Ong, R.8
Mahanian, M.9
Koo, P.10
Bae, S.11
Micic, M.12
Liu, P.T.13
Rosenthal, M.J.14
Fiala, M.15
-
9
-
-
77957369891
-
The biochemical aftermath of anti-amyloid immunotherapy
-
Maarouf CL, Daugs ID, Kokjohn TA, Kalback WM, Patton RL, Luehrs DC, Masliah E, Nicoll JA, Sabbagh MN, Beach TG, Castano EM, Roher AE (2010) The biochemical aftermath of anti-amyloid immunotherapy. Mol Neurodegene 5, 39.
-
(2010)
Mol Neurodegene
, vol.5
, pp. 39
-
-
Maarouf, C.L.1
Daugs, I.D.2
Kokjohn, T.A.3
Kalback, W.M.4
Patton, R.L.5
Luehrs, D.C.6
Masliah, E.7
Nicoll, J.A.8
Sabbagh, M.N.9
Beach, T.G.10
Castano, E.M.11
Roher, A.E.12
-
10
-
-
47149112621
-
42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
-
DOI 10.1016/S0140-6736(08)61075-2, PII S0140673608610752
-
Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JW, Zotova E, Nicoll JA (2008) Long-term effects of Abeta42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial. Lancet 372, 216-223. (Pubitemid 351978111)
-
(2008)
The Lancet
, vol.372
, Issue.9634
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
Bayer, A.6
Jones, R.W.7
Bullock, R.8
Love, S.9
Neal, J.W.10
Zotova, E.11
Nicoll, J.A.12
-
11
-
-
59249103997
-
Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy
-
Zaghi J, Goldenson B, Inayathullah M, Lossinsky AS, Masoumi A, Avagyan H, Mahanian M, Bernas M, Weinand M, Rosenthal MJ, Espinosa-Jeffrey A, de VJ, Teplow DB, Fiala M (2009) Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy. Acta Neuropathol 117, 111-124.
-
(2009)
Acta Neuropathol
, vol.117
, pp. 111-124
-
-
Zaghi, J.1
Goldenson, B.2
Inayathullah, M.3
Lossinsky, A.S.4
Masoumi, A.5
Avagyan, H.6
Mahanian, M.7
Bernas, M.8
Weinand, M.9
Rosenthal, M.J.10
Espinosa-Jeffrey, A.11
De, V.J.12
Teplow, D.B.13
Fiala, M.14
-
12
-
-
33845904135
-
Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid
-
DOI 10.1016/j.neuroscience.2006.10.020, PII S0306452206013650
-
Wilcock DM, Jantzen PT, Li Q, Morgan D, Gordon MN (2007) Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid. Neuroscience 144, 950-960. (Pubitemid 46019842)
-
(2007)
Neuroscience
, vol.144
, Issue.3
, pp. 950-960
-
-
Wilcock, D.M.1
Jantzen, P.T.2
Li, Q.3
Morgan, D.4
Gordon, M.N.5
-
13
-
-
67849110353
-
1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients
-
Masoumi A, Goldenson B, Ghirmai S, Avagyan H, Zaghi J, Abel K, Zheng X, Espinosa-Jeffrey A, Mahanian M, Liu PT, Hewison M, Mizwicki M, Cashman J, Fiala M (2009) 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. J Alzheimers Dis 17, 703-717.
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 703-717
-
-
Masoumi, A.1
Goldenson, B.2
Ghirmai, S.3
Avagyan, H.4
Zaghi, J.5
Abel, K.6
Zheng, X.7
Espinosa-Jeffrey, A.8
Mahanian, M.9
Liu, P.T.10
Hewison, M.11
Mizwicki, M.12
Cashman, J.13
Fiala, M.14
-
14
-
-
77954600272
-
Vitamin D and risk of cognitive decline in elderly persons
-
Llewellyn DJ, Lang IA, Langa KM, Muniz-Terrera G, Phillips CL, Cherubini A, Ferrucci L, Melzer D (2010) Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med 170, 1135-1141.
-
(2010)
Arch Intern Med
, vol.170
, pp. 1135-1141
-
-
Llewellyn, D.J.1
Lang, I.A.2
Langa, K.M.3
Muniz-Terrera, G.4
Phillips, C.L.5
Cherubini, A.6
Ferrucci, L.7
Melzer, D.8
-
15
-
-
79951563916
-
A novel perspective for Alzheimer's disease: Vitamin D receptor suppression by Amyloid-beta and preventing the Amyloid-beta induced alterations by vitamin D in cortical neurons
-
Dursun E, Gezen-Ak D, Yilmazer S (2011) A novel perspective for Alzheimer's disease: Vitamin D receptor suppression by Amyloid-beta and preventing the Amyloid-beta induced alterations by vitamin D in cortical neurons. J Alzheimers Dis 23, 207-201.
-
(2011)
J Alzheimers Dis
, vol.23
, pp. 207-1201
-
-
Dursun, E.1
Gezen-Ak, D.2
Yilmazer, S.3
-
16
-
-
0345874610
-
Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model
-
Norman AW, Mizwicki MT, Norman DPG (2004) Steroid hormone rapid actions, membrane receptors and a conformational ensemble model. Nat Rev Drug Discov 3, 27-41. (Pubitemid 38088696)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.1
, pp. 27-41
-
-
Norman, A.W.1
Mizwicki, M.T.2
Norman, D.P.G.3
-
17
-
-
63649121508
-
Meeting review: Extra-nuclear steroid receptors-Integration with multiple signaling pathways
-
Carbajal L, Deng J, Dressing GE, Hagan CR, Lange CA, Hammes SR (2009) Meeting review: Extra-nuclear steroid receptors-Integration with multiple signaling pathways. Steroids 74, 551-554.
-
(2009)
Steroids
, vol.74
, pp. 551-554
-
-
Carbajal, L.1
Deng, J.2
Dressing, G.E.3
Hagan, C.R.4
Lange, C.A.5
Hammes, S.R.6
-
18
-
-
68849103260
-
The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling
-
Mizwicki MT, Norman AW (2009) The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling. Sci Signal 2, re4.
-
(2009)
Sci Signal
, vol.2
-
-
Mizwicki, M.T.1
Norman, A.W.2
-
19
-
-
34548202165
-
Vitamin D signalling pathways in cancer: Potential for anticancer therapeutics
-
DOI 10.1038/nrc2196, PII NRC2196
-
Deeb KK, Trump DL, Johnson CS (2007) Vitamin D signalling pathways in cancer: Potential for anticancer therapeutics. Nat Rev Cancer 7, 684-700. (Pubitemid 47327412)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.9
, pp. 684-700
-
-
Deeb, K.K.1
Trump, D.L.2
Johnson, C.S.3
-
20
-
-
0030611087
-
3of whole cell chloride currents in osteoblastic ROS 17/2.8 cells: A structure-function study
-
3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells: A structure-function study. J Biol Chem 272, 22617-22622.
-
(1997)
J Biol Chem
, vol.272
, pp. 22617-22622
-
-
Zanello, L.P.1
Norman, A.W.2
-
21
-
-
77954761672
-
A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): Structure-function implications
-
Mizwicki MT, Menegaz D, Yaghmaei S, Henry HL, Norman AW (2010) A molecular description of ligand binding to the two overlapping binding pockets of the nuclear vitamin D receptor (VDR): Structure-function implications. J Steroid Biochem Mol Biol 121, 98-105.
-
(2010)
J Steroid Biochem Mol Biol
, vol.121
, pp. 98-105
-
-
Mizwicki, M.T.1
Menegaz, D.2
Yaghmaei, S.3
Henry, H.L.4
Norman, A.W.5
-
22
-
-
79960978543
-
Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP)
-
Menegaz D, Mizwicki MT, Barrientos-Duran A, Chen N, Henry HL, Norman AW (2011) Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP). Mol Endocrinol 25, 1289-1300.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1289-1300
-
-
Menegaz, D.1
Mizwicki, M.T.2
Barrientos-Duran, A.3
Chen, N.4
Henry, H.L.5
Norman, A.W.6
-
23
-
-
68949147935
-
1alpha,25(OH)(2) Vitamin D(3) Induction of ATP Secretion in Osteoblasts
-
Biswas P, Zanello LP (2009) 1alpha,25(OH)(2) Vitamin D(3) Induction of ATP Secretion in Osteoblasts. J Bone Miner Res 24, 1450-1460.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 1450-1460
-
-
Biswas, P.1
Zanello, L.P.2
-
24
-
-
34548852606
-
CLC chloride channels and transporters: A biophysical and physiological perspective
-
Zifarelli G, Pusch M (2007) CLC chloride channels and transporters: A biophysical and physiological perspective. Rev Physiol Biochem Pharmacol 158, 23-76.
-
(2007)
Rev Physiol Biochem Pharmacol
, vol.158
, pp. 23-76
-
-
Zifarelli, G.1
Pusch, M.2
-
25
-
-
77951782126
-
Chloride channels: Often enigmatic, rarely predictable
-
Duran C, Thompson CH, Xiao Q, Hartzell HC (2010) Chloride channels: Often enigmatic, rarely predictable. Annu Rev Physiol 72, 95-121.
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 95-121
-
-
Duran, C.1
Thompson, C.H.2
Xiao, Q.3
Hartzell, H.C.4
-
26
-
-
12544249991
-
ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation
-
Hara-Chikuma M, Yang B, Sonawane ND, Sasaki S, Uchida S, Verkman AS (2005) ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation. J Biol Chem 280, 1241-1247.
-
(2005)
J Biol Chem
, vol.280
, pp. 1241-1247
-
-
Hara-Chikuma, M.1
Yang, B.2
Sonawane, N.D.3
Sasaki, S.4
Uchida, S.5
Verkman, A.S.6
-
27
-
-
33744963881
-
Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration
-
DOI 10.1074/jbc.M511030200
-
Moreland JG, Davis AP, Bailey G, Nauseef WM, Lamb FS (2006) Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration. J Biol Chem 281, 12277-12288. (Pubitemid 43855312)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.18
, pp. 12277-12288
-
-
Moreland, J.G.1
Davis, A.P.2
Bailey, G.3
Nauseef, W.M.4
Lamb, F.S.5
-
28
-
-
0023597394
-
Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophages
-
DOI 10.1083/jcb.105.6.2685
-
Kruskal BA, Maxfield FR (1987) Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophages. J Cell Biol 105, 2685-2693. (Pubitemid 18017699)
-
(1987)
Journal of Cell Biology
, vol.105
, Issue.6 I
, pp. 2685-2693
-
-
Kruskal, B.A.1
Maxfield, F.R.2
-
29
-
-
35348944726
-
The ClC-3 chloride transport protein traffics through the plasma membrane via interaction of an N-terminal dileucine cluster with clathrin
-
DOI 10.1074/jbc.M703506200
-
Zhao Z, Li X, Hao J, Winston JH, Weinman SA (2007) The ClC-3 chloride transport protein traffics through the plasma membrane via interaction of an N-terminal dileucine cluster with clathrin. J Biol Chem 282, 29022-29031. (Pubitemid 47606048)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.39
, pp. 29022-29031
-
-
Zhao, Z.1
Li, X.2
Hao, J.3
Winston, J.H.4
Weinman, S.A.5
-
30
-
-
54349128338
-
An expanded biological repertoire for Ins(3,4,5,6)P4 through its modulation of ClC-3 function
-
Mitchell J, Wang X, Zhang G, Gentzsch M, Nelson DJ, Shears SB (2008) An expanded biological repertoire for Ins(3,4,5,6)P4 through its modulation of ClC-3 function. Curr Biol 18, 1600-1605.
-
(2008)
Curr Biol
, vol.18
, pp. 1600-1605
-
-
Mitchell, J.1
Wang, X.2
Zhang, G.3
Gentzsch, M.4
Nelson, D.J.5
Shears, S.B.6
-
31
-
-
56349137676
-
Anion channels: Regulation of ClC-3 by an orphan second messenger
-
Alekov AK, Fahlke C (2008) Anion channels: Regulation of ClC-3 by an orphan second messenger. Curr Biol 18, R1061-R1064.
-
(2008)
Curr Biol
, vol.18
-
-
Alekov, A.K.1
Fahlke, C.2
-
32
-
-
0035827526
-
Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase
-
Huang P, Liu J, Di A, Robinson NC, Musch MW, Kaetzel MA, Nelson DJ (2001) Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase. J Biol Chem 276, 20093-20100.
-
(2001)
J Biol Chem
, vol.276
, pp. 20093-20100
-
-
Huang, P.1
Liu, J.2
Di, A.3
Robinson, N.C.4
Musch, M.W.5
Kaetzel, M.A.6
Nelson, D.J.7
-
33
-
-
77950297294
-
1alpha,25(OH)(2)-Vitamin D(3) stimulation of secretion via chloride channel activation in Sertoli cells
-
Menegaz D, Barrientos-Duran A, Kline A, Silva FR, Norman AW, Mizwicki MT, Zanello LP (2010) 1alpha,25(OH)(2)-Vitamin D(3) stimulation of secretion via chloride channel activation in Sertoli cells. J Steroid Biochem Mol Biol 119, 127-134.
-
(2010)
J Steroid Biochem Mol Biol
, vol.119
, pp. 127-134
-
-
Menegaz, D.1
Barrientos-Duran, A.2
Kline, A.3
Silva, F.R.4
Norman, A.W.5
Mizwicki, M.T.6
Zanello, L.P.7
-
34
-
-
33144462544
-
Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry
-
DOI 10.1021/ac051294f
-
Chalmers MJ, Busby SA, Pascal BD, He Y, Hendrickson CL, Marshall AG, Griffin PR (2006) Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry. Anal Chem 78, 1005-1014. (Pubitemid 43271829)
-
(2006)
Analytical Chemistry
, vol.78
, Issue.4
, pp. 1005-1014
-
-
Chalmers, M.J.1
Busby, S.A.2
Pascal, B.D.3
He, Y.4
Hendrickson, C.L.5
Marshall, A.G.6
Griffin, P.R.7
-
35
-
-
62149090281
-
HD desktop: An integrated platform for the analysis and visualization of H/D exchange data
-
Pascal BD, Chalmers MJ, Busby SA, Griffin PR (2009) HD desktop: An integrated platform for the analysis and visualization of H/D exchange data. J Am Soc Mass Spectrom 20, 601-610.
-
(2009)
J Am Soc Mass Spectrom
, vol.20
, pp. 601-610
-
-
Pascal, B.D.1
Chalmers, M.J.2
Busby, S.A.3
Griffin, P.R.4
-
36
-
-
0034282395
-
Myo-inositol 3,4,5,6-tetrakisphosphate inhibits an apical calcium-activated chloride conductance in polarized monolayers of a cystic fibrosis cell line
-
Carew MA, Yang X, Schultz C, Shears SB (2000) myo-inositol 3,4,5,6-tetrakisphosphate inhibits an apical calcium-activated chloride conductance in polarized monolayers of a cystic fibrosis cell line. J Biol Chem 275, 26906-26913.
-
(2000)
J Biol Chem
, vol.275
, pp. 26906-26913
-
-
Carew, M.A.1
Yang, X.2
Schultz, C.3
Shears, S.B.4
-
37
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
DOI 10.1074/jbc.273.29.18623
-
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273, 18623-18632. (Pubitemid 28334795)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.29
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
38
-
-
18944372230
-
Rho kinase, a promising drug target for neurological disorders
-
DOI 10.1038/nrd1719
-
Mueller BK, Mack H, Teusch N (2005) Rho kinase, a promising drug target for neurological disorders. Nat Rev Drug Discov 4, 387-398. (Pubitemid 40704122)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.5
, pp. 387-398
-
-
Mueller, B.K.1
Mack, H.2
Teusch, N.3
-
39
-
-
77957770064
-
Hydrogen/Deuterium Exchange Reveals Distinct Agonist/Partial Agonist Receptor Dynamics within Vitamin D Receptor/Retinoid X Receptor Heterodimer
-
Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Garcia-Ordonez RD, Pascal BD, Burris TP, Dodge JA, Griffin PR (2010) Hydrogen/Deuterium Exchange Reveals Distinct Agonist/Partial Agonist Receptor Dynamics within Vitamin D Receptor/Retinoid X Receptor Heterodimer. Structure 18, 1332-1341.
-
(2010)
Structure
, vol.18
, pp. 1332-1341
-
-
Zhang, J.1
Chalmers, M.J.2
Stayrook, K.R.3
Burris, L.L.4
Garcia-Ordonez, R.D.5
Pascal, B.D.6
Burris, T.P.7
Dodge, J.A.8
Griffin, P.R.9
-
40
-
-
73649094774
-
On the mechanism underlying (23S)-25-dehydro-1alpha(OH)-vitamin D3-26,23-lactone antagonism of hVDRwt gene activation and its switch to a superagonist
-
Mizwicki MT, Bula CM, Mahinthichaichan P, Henry HL, Ishizuka S, Norman AW (2009) On the mechanism underlying (23S)-25-dehydro-1alpha(OH)-vitamin D3-26,23-lactone antagonism of hVDRwt gene activation and its switch to a superagonist. J Biol Chem 284, 36292-36301.
-
(2009)
J Biol Chem
, vol.284
, pp. 36292-36301
-
-
Mizwicki, M.T.1
Bula, C.M.2
Mahinthichaichan, P.3
Henry, H.L.4
Ishizuka, S.5
Norman, A.W.6
-
41
-
-
0142028937
-
Kinases, Homology Models, and High Throughput Docking
-
DOI 10.1021/jm020503a
-
Diller DJ, Li R (2003) Kinases, homology models, and high throughput docking. J Med Chem 46, 4638-4647. (Pubitemid 37271613)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.22
, pp. 4638-4647
-
-
Diller, D.J.1
Li, R.2
-
43
-
-
77958561665
-
Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-kappaB activation
-
Song WB, Wang YY, Meng FS, Zhang QH, Zeng JY, Xiao LP, Yu XP, Peng DD, Su L, Xiao B, Zhang ZS (2010) Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-kappaB activation. PLoS ONE 5, e12969.
-
(2010)
PLoS ONE
, vol.5
-
-
Song, W.B.1
Wang, Y.Y.2
Meng, F.S.3
Zhang, Q.H.4
Zeng, J.Y.5
Xiao, L.P.6
Yu, X.P.7
Peng, D.D.8
Su, L.9
Xiao, B.10
Zhang, Z.S.11
-
44
-
-
33750727091
-
P38 MAP-kinase pathway is involved in the production of CLC-3 in nasal epithelial cells with allergic rhinitis induced by interleukin-4
-
DOI 10.1097/01.mlg.0000236078.81313.c8, PII 0000553720061100000007
-
Han D, Zhou B, Cheng L, Oh Y, Li H (2006) P38 MAP-kinase pathway is involved in the production of CLC-3 in nasal epithelial cells with allergic rhinitis induced by interleukin-4. Laryngoscope 116, 1973-1977. (Pubitemid 44704376)
-
(2006)
Laryngoscope
, vol.116
, Issue.11
, pp. 1973-1977
-
-
Han, D.1
Zhou, B.2
Cheng, L.3
Oh, Y.4
Li, H.5
-
45
-
-
8744264023
-
The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific
-
DOI 10.1074/jbc.M404101200
-
Narayanan R, Sepulveda VA, Falzon M, Weigel NL (2004) The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific. J Biol Chem 279, 47298-47310. (Pubitemid 39518387)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.45
, pp. 47298-47310
-
-
Narayanan, R.1
Tovar, S.V.A.2
Falzon, M.3
Weigel, N.L.4
-
46
-
-
33947108954
-
3 and its receptor
-
DOI 10.1016/j.jsbmb.2006.12.050, PII S0960076006004274
-
Pike JW, Meyer MB, Watanuki M, Kim S, Zella LA, Fretz JA, Yamazaki M, Shevde NK (2007) Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor. J Steroid Biochem Mol Biol 103, 389-395. (Pubitemid 46401339)
-
(2007)
Journal of Steroid Biochemistry and Molecular Biology
, vol.103
, Issue.3-5
, pp. 389-395
-
-
Pike, J.W.1
Meyer, M.B.2
Watanuki, M.3
Kim, S.4
Zella, L.A.5
Fretz, J.A.6
Yamazaki, M.7
Shevde, N.K.8
-
47
-
-
0032893076
-
AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: Requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation
-
DOI 10.1210/en.140.1.63
-
Aslam F, McCabe L, Frenkel B, Van Wijnen AJ, Stein GS, Lian JB, Stein JL (1999) AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: Requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation. Endocrinology 140, 63-70. (Pubitemid 29011142)
-
(1999)
Endocrinology
, vol.140
, Issue.1
, pp. 63-70
-
-
Aslam, F.1
McCabe, L.2
Frenkel, B.3
Van Wijnen, A.J.4
Stein, G.S.5
Lian, J.B.6
Stein, J.L.7
-
48
-
-
77949873898
-
Vitamin D controls T cell antigen receptor signaling and activation of human T cells
-
von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C (2010) Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat Immunol 11, 344-349.
-
(2010)
Nat Immunol
, vol.11
, pp. 344-349
-
-
Von Essen, M.R.1
Kongsbak, M.2
Schjerling, P.3
Olgaard, K.4
Odum, N.5
Geisler, C.6
-
49
-
-
0035871888
-
3, that modulates cell growth, differentiation, apoptosis, cell cycle, and induction of PTEN in leukemic cells
-
DOI 10.1182/blood.V97.8.2427
-
Hisatake J, O'Kelly J, Uskokovic MR, Tomoyasu S, Koeffler HP (2001) Novel vitamin D(3) analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D(3), that modulates cell growth, differentiation, apoptosis, cell cycle, and induction of PTEN in leukemic cells. Blood 97, 2427-2433. (Pubitemid 32291490)
-
(2001)
Blood
, vol.97
, Issue.8
, pp. 2427-2433
-
-
Hisatake, J.-I.1
O'Kelly, J.2
Uskokovic, M.R.3
Tomoyasu, S.4
Koeffler, H.P.5
-
50
-
-
79952303913
-
The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons
-
Gezen-Ak D, Dursun E, Yilmazer S (2011) The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons. PLoS ONE 6, e17553.
-
(2011)
PLoS ONE
, vol.6
-
-
Gezen-Ak, D.1
Dursun, E.2
Yilmazer, S.3
|