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Volumn 72, Issue 6, 2013, Pages 489-504

Mediation of protection and recovery from experimental autoimmune encephalomyelitis by macrophages expressing the human voltage-gated sodium channel NaV1.5

Author keywords

Alternative activation; Experimental autoimmune encephalomyelitis; Macrophage; Multiple sclerosis; Sodium channel

Indexed keywords

ARGINASE 1; SODIUM CHANNEL NAV1.5; UVOMORULIN;

EID: 84878660383     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e318293eb08     Document Type: Article
Times cited : (15)

References (42)
  • 2
    • 84861689883 scopus 로고    scopus 로고
    • Current immunotherapy of multiple sclerosis and future challenges: Relevance of immune-mediated repair
    • Carrithers MD. Current immunotherapy of multiple sclerosis and future challenges: Relevance of immune-mediated repair. Curr Pharm Biotechnol 2012;13:1409-17
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 1409-1417
    • Carrithers, M.D.1
  • 3
    • 69049084375 scopus 로고    scopus 로고
    • Toll-like receptor 2 and poly (ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
    • Farez MF, Quintana FJ, Gandhi R, et al. Toll-like receptor 2 and poly (ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat Immunol 2009;10:958-64
    • (2009) Nat Immunol , vol.10 , pp. 958-964
    • Farez, M.F.1    Quintana, F.J.2    Gandhi, R.3
  • 4
    • 66549130329 scopus 로고    scopus 로고
    • The relation between inflammation and neurodegeneration in multiple sclerosis brains
    • Frischer JM, Bramow S, Dal-Bianco A, et al. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 2009;132:1175-89
    • (2009) Brain , vol.132 , pp. 1175-1189
    • Frischer, J.M.1    Bramow, S.2    Dal-Bianco, A.3
  • 5
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux F, Greter M, Leboeuf M, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 2010; 330:841-45
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3
  • 6
    • 0242551508 scopus 로고    scopus 로고
    • Metchnikoff and the phagocytosis theory
    • Tauber AI. Metchnikoff and the phagocytosis theory. Nat Rev Mol Cell Biol 2003;4:897-901
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 897-901
    • Tauber, A.I.1
  • 7
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol 2011;11:723-37
    • (2011) Nat Rev Immunol , vol.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 8
    • 34250211729 scopus 로고    scopus 로고
    • Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification
    • Carrithers M, Dib-Hajj S, Carrithers L, et al. Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification. J Immunol 2007;178:7822-32
    • (2007) J Immunol , vol.178 , pp. 7822-7832
    • Carrithers, M.1    Dib-Hajj, S.2    Carrithers, L.3
  • 9
    • 65549133825 scopus 로고    scopus 로고
    • Regulation of podosome formation in macrophages by a splice variant of the sodium channel SCN8A
    • Carrithers MD, Chatterjee G, Carrithers LM, et al. Regulation of podosome formation in macrophages by a splice variant of the sodium channel SCN8A. J Biol Chem 2009;284:8114-26
    • (2009) J Biol Chem , vol.284 , pp. 8114-8126
    • Carrithers, M.D.1    Chatterjee, G.2    Carrithers, L.M.3
  • 10
    • 80755126973 scopus 로고    scopus 로고
    • The human macrophage sodium channel NaV1.5 regulates mycobacteria processing through organelle polarization and localized calcium oscillations
    • Carrithers LM, Hulseberg P, Sandor M, et al. The human macrophage sodium channel NaV1.5 regulates mycobacteria processing through organelle polarization and localized calcium oscillations. FEMS Immunol Med Microbiol 2011;63:319-27
    • (2011) FEMS Immunol Med Microbiol , vol.63 , pp. 319-327
    • Carrithers, L.M.1    Hulseberg, P.2    Sandor, M.3
  • 11
    • 13244258365 scopus 로고    scopus 로고
    • Sodium channels contribute to microglia/macrophage activation and function in EAE and MS
    • Craner M, Damarjian T, Liu S, et al. Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia 2005;49:220-29
    • (2005) Glia , vol.49 , pp. 220-229
    • Craner, M.1    Damarjian, T.2    Liu, S.3
  • 12
    • 84876043770 scopus 로고    scopus 로고
    • Nav1.5 sodium channels in macrophages in multiple sclerosis lesions
    • Black JA, Newcombe J, Waxman SG. Nav1.5 sodium channels in macrophages in multiple sclerosis lesions. Mult Scler 2013;19:532-42
    • (2013) Mult Scler , vol.19 , pp. 532-542
    • Black, J.A.1    Newcombe, J.2    Waxman, S.G.3
  • 13
    • 0037062989 scopus 로고    scopus 로고
    • Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment
    • Brown S, Heinisch I, Ross E, et al. Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment. Nature 2002;418:200-3
    • (2002) Nature , vol.418 , pp. 200-203
    • Brown, S.1    Heinisch, I.2    Ross, E.3
  • 14
    • 0037307026 scopus 로고    scopus 로고
    • A macrophage colonystimulating factor receptorYgreen fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse
    • Sasmono RT, Oceandy D, Pollard JW, et al. A macrophage colonystimulating factor receptorYgreen fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood 2003;101:1155-63
    • (2003) Blood , vol.101 , pp. 1155-1163
    • Sasmono, R.T.1    Oceandy, D.2    Pollard, J.W.3
  • 15
    • 34347226291 scopus 로고    scopus 로고
    • Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice
    • Carrither SMD, Carrithers LM, Czyzyk J, et al. Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice. J Neuroimmunol 2007;187:31-43
    • (2007) J Neuroimmunol , vol.187 , pp. 31-43
    • Carrither, S.M.D.1    Carrithers, L.M.2    Czyzyk, J.3
  • 16
    • 46849092175 scopus 로고    scopus 로고
    • Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Anderson JM, Hampton DW, Patani R, et al. Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain 2008;131:1736-48
    • (2008) Brain , vol.131 , pp. 1736-1748
    • Anderson, J.M.1    Hampton, D.W.2    Patani, R.3
  • 17
    • 0034123924 scopus 로고    scopus 로고
    • Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment
    • Carrithers MD, Visintin I, Kang SJ, et al. Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment. Brain 2000;123:1092-101
    • (2000) Brain , vol.123 , pp. 1092-1101
    • Carrithers, M.D.1    Visintin, I.2    Kang, S.J.3
  • 18
    • 79955142455 scopus 로고    scopus 로고
    • Characterization of epithelial V-like antigen in human choroid plexus epithelial cells: Potential role in CNS immune surveillance
    • Wojcik E, Carrithers LM, Carrithers MD. Characterization of epithelial V-like antigen in human choroid plexus epithelial cells: Potential role in CNS immune surveillance. Neurosci Lett 2011;495:115-20
    • (2011) Neurosci Lett , vol.495 , pp. 115-120
    • Wojcik, E.1    Carrithers, L.M.2    Carrithers, M.D.3
  • 19
    • 0033802454 scopus 로고    scopus 로고
    • In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity
    • Brabb T, von Dassow P, Ordonez N, et al. In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity. J Exp Med 2000;192:871-80
    • (2000) J Exp Med , vol.192 , pp. 871-880
    • Brabb, T.1    Von Dassow, P.2    Ordonez, N.3
  • 20
    • 79953729333 scopus 로고    scopus 로고
    • Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity
    • Hume DA. Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity. J Leukoc Biol 2011;89:525-38
    • (2011) J Leukoc Biol , vol.89 , pp. 525-538
    • Hume, D.A.1
  • 21
    • 66349084135 scopus 로고    scopus 로고
    • Arginase-1- expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis
    • Pesce JT, Ramalingam TR, Mentink-Kane MM, et al. Arginase-1- expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis. PLoS Pathog 2009;5
    • (2009) PLoS Pathog , vol.5
    • Pesce, J.T.1    Ramalingam, T.R.2    Mentink-Kane, M.M.3
  • 22
    • 37249085025 scopus 로고    scopus 로고
    • IL-4 promotes the formation of multinucleated giant cells from macrophage precursors by a STAT6-dependent, homotypic mechanism: Contribution of E-cadherin
    • Moreno JL, Mikhailenko I, Tondravi MM, et al. IL-4 promotes the formation of multinucleated giant cells from macrophage precursors by a STAT6-dependent, homotypic mechanism: Contribution of E-cadherin. J Leukoc Biol 2007;82:1542-53
    • (2007) J Leukoc Biol , vol.82 , pp. 1542-1553
    • Moreno, J.L.1    Mikhailenko, I.2    Tondravi, M.M.3
  • 23
    • 0017075792 scopus 로고
    • The granulomatous inflammatory response. A review
    • Adams DO. The granulomatous inflammatory response. A review. Am J Pathol 1976;84:164-92
    • (1976) Am J Pathol , vol.84 , pp. 164-192
    • Adams, D.O.1
  • 24
    • 0025227919 scopus 로고
    • Mechanisms of injury to the central nervous system following experimental cytomegalovirus infection
    • Booss J, Dann PR, Winkler SR, et al. Mechanisms of injury to the central nervous system following experimental cytomegalovirus infection. Am J Otolaryngol 1990;11:313-17
    • (1990) Am J Otolaryngol , vol.11 , pp. 313-317
    • Booss, J.1    Dann, P.R.2    Winkler, S.R.3
  • 25
    • 0030049858 scopus 로고    scopus 로고
    • Microglial nodule encephalitis: Limited CNS infection despite disseminated systemic cryptococcosis
    • Edelman M, Birkenhauer MC, Steinberg JJ, et al. Microglial nodule encephalitis: Limited CNS infection despite disseminated systemic cryptococcosis. Clin Neuropathol 1996;15:30-33
    • (1996) Clin Neuropathol , vol.15 , pp. 30-33
    • Edelman, M.1    Birkenhauer, M.C.2    Steinberg, J.J.3
  • 26
    • 0037104645 scopus 로고    scopus 로고
    • Arginase i and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro
    • Cai D, Deng K, Mellado W, et al. Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro. Neuron 2002;35:711-19
    • (2002) Neuron , vol.35 , pp. 711-719
    • Cai, D.1    Deng, K.2    Mellado, W.3
  • 27
    • 68049147011 scopus 로고    scopus 로고
    • Increased synthesis of spermidine as a result of upregulation of arginase i promotes axonal regeneration in culture and in vivo
    • Deng K, He H, Qiu J, et al. Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo. J Neurosci 2009;29:9545-52
    • (2009) J Neurosci , vol.29 , pp. 9545-9552
    • Deng, K.1    He, H.2    Qiu, J.3
  • 28
    • 84859801125 scopus 로고    scopus 로고
    • Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis
    • Ahn M, Yang W, Kim H, et al. Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis. Brain Res 2012;1453:77-86
    • (2012) Brain Res , vol.1453 , pp. 77-86
    • Ahn, M.1    Yang, W.2    Kim, H.3
  • 29
    • 33846194125 scopus 로고    scopus 로고
    • Innate immunityYcross-talk with adaptive immunity through pattern recognition receptors and cytokines
    • Kabelitz D, Medzhitov R. Innate immunityYcross-talk with adaptive immunity through pattern recognition receptors and cytokines. Curr Opin Immunol 2007;19:1-3
    • (2007) Curr Opin Immunol , vol.19 , pp. 1-3
    • Kabelitz, D.1    Medzhitov, R.2
  • 30
    • 84862908705 scopus 로고    scopus 로고
    • Rejuvenation of regeneration in the aging central nervous system
    • Ruckh JM, Zhao JW, Shadrach JL, et al. Rejuvenation of regeneration in the aging central nervous system. Cell Stem Cell 2012;10:96-103
    • (2012) Cell Stem Cell , vol.10 , pp. 96-103
    • Ruckh, J.M.1    Zhao, J.W.2    Shadrach, J.L.3
  • 31
    • 34147115541 scopus 로고    scopus 로고
    • Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
    • ElKhoury J, ToftM, Hickman SE, et al. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med 2007;13:432-38
    • (2007) Nat Med , vol.13 , pp. 432-438
    • Elkhoury, J.1    Toftm Hickman, S.E.2
  • 32
    • 80052561392 scopus 로고    scopus 로고
    • Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke
    • Faustino JV, Wang X, Johnson CE, et al. Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke. J Neurosci 2011;31:12992-3001
    • (2011) J Neurosci , vol.31 , pp. 12992-13001
    • Faustino, J.V.1    Wang, X.2    Johnson, C.E.3
  • 33
    • 84872088087 scopus 로고    scopus 로고
    • Variant of trem2 associated with the risk of alzheimer's disease
    • Jonsson T, Stefansson H, Steinberg S, et al. Variant of TREM2 Associated with the Risk of Alzheimer's Disease. N Engl J Med 2013; 368:107-16
    • (2013) N Engl J Med , vol.368 , pp. 107-116
    • Jonsson, T.1    Stefansson, H.2    Steinberg, S.3
  • 34
    • 77953476309 scopus 로고    scopus 로고
    • Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: A randomised, double-blind, placebo-controlled, parallel-group trial
    • Kapoor R, Furby J, Hayton T, et al. Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: A randomised, double-blind, placebo-controlled, parallel-group trial. Lancet Neurol 2010;9:681-88
    • (2010) Lancet Neurol , vol.9 , pp. 681-688
    • Kapoor, R.1    Furby, J.2    Hayton, T.3
  • 35
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3:23-35
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 36
    • 0020502358 scopus 로고
    • Identification of interferongamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity
    • Nathan CF, Murray HW, Wiebe ME, et al. Identification of interferongamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med 1983;158:670-89
    • (1983) J Exp Med , vol.158 , pp. 670-689
    • Nathan, C.F.1    Murray, H.W.2    Wiebe, M.E.3
  • 37
    • 34547699396 scopus 로고    scopus 로고
    • Type II monocytes modulate T cellYmediated central nervous system autoimmune disease
    • Weber MS, Prod'homme T, Youssef S, et al. Type II monocytes modulate T cellYmediated central nervous system autoimmune disease. Nat Med 2007;13:935-43
    • (2007) Nat Med , vol.13 , pp. 935-943
    • Weber, M.S.1    Prod'Homme, T.2    Youssef, S.3
  • 38
    • 77954961992 scopus 로고    scopus 로고
    • Macrophages: Master regulators of inflammation and fibrosis
    • Wynn TA, Barron L. Macrophages: Master regulators of inflammation and fibrosis. Semin Liver Dis 2010;30:245-57
    • (2010) Semin Liver Dis , vol.30 , pp. 245-257
    • Wynn, T.A.1    Barron, L.2
  • 39
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: In vivo veritas. J Clin Invest 2012;122:787-95
    • (2012) J Clin Invest , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 40
    • 81255142093 scopus 로고    scopus 로고
    • From inflammation to wound healing: Using a simple model to understand the functional versatility of murine macrophages
    • Childs LM, Paskow M, Morris SM Jr, et al. From inflammation to wound healing: Using a simple model to understand the functional versatility of murine macrophages. Bull Math Biol 2011;73:2575-604
    • (2011) Bull Math Biol , vol.73 , pp. 2575-2604
    • Childs, L.M.1    Paskow, M.2    Morris Jr., S.M.3
  • 41
    • 65549115862 scopus 로고    scopus 로고
    • Plasticity of CD4+ T cell lineage differentiation
    • Zhou L, Chong MM, Littman DR. Plasticity of CD4+ T cell lineage differentiation. Immunity 2009;30:646-55
    • (2009) Immunity , vol.30 , pp. 646-655
    • Zhou, L.1    Chong, M.M.2    Littman, D.R.3
  • 42
    • 0035511981 scopus 로고    scopus 로고
    • Macrophage activation syndrome: A potentially fatal complication of rheumatic disorders
    • Sawhney S, Woo P, Murray KJ. Macrophage activation syndrome: A potentially fatal complication of rheumatic disorders. Arch Dis Child 2001;85:421-26
    • (2001) Arch Dis Child , vol.85 , pp. 421-426
    • Sawhney, S.1    Woo, P.2    Murray, K.J.3


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