-
1
-
-
0034618094
-
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
-
Babbe H., Roers A., Waisman A., Lassmann H., Goebels N., Hohlfeld R., Friese M., Schroder R., Deckert M., Schmidt S., Ravid R., and Rajewsky K. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J. Exp. Med. 192 (2000) 393-404
-
(2000)
J. Exp. Med.
, vol.192
, pp. 393-404
-
-
Babbe, H.1
Roers, A.2
Waisman, A.3
Lassmann, H.4
Goebels, N.5
Hohlfeld, R.6
Friese, M.7
Schroder, R.8
Deckert, M.9
Schmidt, S.10
Ravid, R.11
Rajewsky, K.12
-
2
-
-
0027529932
-
Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma
-
Baron J.L., Madri J.A., Ruddle N.H., Hashim G., and Janeway Jr. C.A. Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 177 (1993) 57-68
-
(1993)
J. Exp. Med.
, vol.177
, pp. 57-68
-
-
Baron, J.L.1
Madri, J.A.2
Ruddle, N.H.3
Hashim, G.4
Janeway Jr., C.A.5
-
3
-
-
22844438117
-
Progressive multifocal leukoencephalopathy and natalizumab-unforeseen consequences
-
Berger J.R., and Koralnik I.J. Progressive multifocal leukoencephalopathy and natalizumab-unforeseen consequences. N. Engl. J. Med. 353 (2005) 414-416
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 414-416
-
-
Berger, J.R.1
Koralnik, I.J.2
-
4
-
-
0021079164
-
Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis
-
Booss J., Esiri M., Tourtellotte W., and Mason D. Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis. J. Neurol. Sci. 62 (1983) 219-232
-
(1983)
J. Neurol. Sci.
, vol.62
, pp. 219-232
-
-
Booss, J.1
Esiri, M.2
Tourtellotte, W.3
Mason, D.4
-
5
-
-
0033802454
-
In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity
-
Brabb T., Von Dassow P., Ordonez N., Schnabel B., Duke B., and Goverman J. In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity. J. Exp. Med. 192 (2000) 871-880
-
(2000)
J. Exp. Med.
, vol.192
, pp. 871-880
-
-
Brabb, T.1
Von Dassow, P.2
Ordonez, N.3
Schnabel, B.4
Duke, B.5
Goverman, J.6
-
6
-
-
0036341221
-
Dependence of cellular phenotype and genetic background on immune surveillance of the brain by T lymphocytes
-
Carrithers M.D., Visintin I., and Janeway Jr. C.A. Dependence of cellular phenotype and genetic background on immune surveillance of the brain by T lymphocytes. J. Neuroimmunol. 129 (2002) 51-57
-
(2002)
J. Neuroimmunol.
, vol.129
, pp. 51-57
-
-
Carrithers, M.D.1
Visintin, I.2
Janeway Jr., C.A.3
-
7
-
-
0034123924
-
Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment
-
Carrithers M.D., Visintin I., Kang S.J., and Janeway Jr. C.A. Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment. Brain 123 (2000) 1092-1101
-
(2000)
Brain
, vol.123
, pp. 1092-1101
-
-
Carrithers, M.D.1
Visintin, I.2
Kang, S.J.3
Janeway Jr., C.A.4
-
8
-
-
0035164119
-
Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis
-
Cepok S., Jacobsen M., Schock S., Omer B., Jaekel S., Boddeker I., Oertel W.H., Sommer N., and Hemmer B. Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. Brain 124 (2001) 2169-2176
-
(2001)
Brain
, vol.124
, pp. 2169-2176
-
-
Cepok, S.1
Jacobsen, M.2
Schock, S.3
Omer, B.4
Jaekel, S.5
Boddeker, I.6
Oertel, W.H.7
Sommer, N.8
Hemmer, B.9
-
9
-
-
0034601012
-
Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis (EAE)
-
Chu C.Q., Wittmer S., and Dalton D.K. Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis (EAE). J. Exp. Med. 192 (2000) 123-128
-
(2000)
J. Exp. Med.
, vol.192
, pp. 123-128
-
-
Chu, C.Q.1
Wittmer, S.2
Dalton, D.K.3
-
10
-
-
23744475685
-
The ins and outs of T lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms
-
Engelhardt B., and Ransohoff R.M. The ins and outs of T lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol. 26 (2005) 485-495
-
(2005)
Trends Immunol.
, vol.26
, pp. 485-495
-
-
Engelhardt, B.1
Ransohoff, R.M.2
-
11
-
-
0029671318
-
Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis
-
Ferber I.A., Brocke S., Taylor-Edwards C., Ridgeway W., Dinisco C., Steinman L., Dalton D., and Fathman C.G. Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis. J. Immunol. 156 (1996) 5-7
-
(1996)
J. Immunol.
, vol.156
, pp. 5-7
-
-
Ferber, I.A.1
Brocke, S.2
Taylor-Edwards, C.3
Ridgeway, W.4
Dinisco, C.5
Steinman, L.6
Dalton, D.7
Fathman, C.G.8
-
12
-
-
23444434940
-
Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?
-
Friese M.A., and Fugger L. Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?. Brain 128 (2005) 1747-1763
-
(2005)
Brain
, vol.128
, pp. 1747-1763
-
-
Friese, M.A.1
Fugger, L.2
-
13
-
-
0035423415
-
Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes
-
Furlan R., Brambilla E., Ruffini F., Poliani P.L., Bergami A., Marconi P.C., Franciotta D.M., Penna G., Comi G., Adorini L., and Martino G. Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes. J. Immunol. 167 (2001) 1821-1829
-
(2001)
J. Immunol.
, vol.167
, pp. 1821-1829
-
-
Furlan, R.1
Brambilla, E.2
Ruffini, F.3
Poliani, P.L.4
Bergami, A.5
Marconi, P.C.6
Franciotta, D.M.7
Penna, G.8
Comi, G.9
Adorini, L.10
Martino, G.11
-
14
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold R., Linington C., and Lassmann H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129 (2006) 1953-1971
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
15
-
-
0025981021
-
T-lymphocyte entry into the central nervous system
-
Hickey W.F., Hsu B.L., and Kimura H. T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 128 (1991) 254-260
-
(1991)
J. Neurosci. Res.
, vol.128
, pp. 254-260
-
-
Hickey, W.F.1
Hsu, B.L.2
Kimura, H.3
-
16
-
-
0035801332
-
A pathogenic role for myelin specific CD8(+) T cells in a model for multiple sclerosis
-
Huseby E.S., Liggitt D., Brabb T., Schnabel B., Ohlen C., and Goverman J. A pathogenic role for myelin specific CD8(+) T cells in a model for multiple sclerosis. J. Exp. Med. 194 (2001) 669-676
-
(2001)
J. Exp. Med.
, vol.194
, pp. 669-676
-
-
Huseby, E.S.1
Liggitt, D.2
Brabb, T.3
Schnabel, B.4
Ohlen, C.5
Goverman, J.6
-
17
-
-
0036191549
-
Oligoclonal expansion of memory CD8(+) T cells in cerebrospinal fluid from multiple sclerosis patients
-
Jacobsen M., Cepok S., Quak E., Happel M., Gaber R., Ziegler A., Schock S., Oertel W.H., Sommer N., and Hemmer B. Oligoclonal expansion of memory CD8(+) T cells in cerebrospinal fluid from multiple sclerosis patients. Brain 125 (2002) 538-550
-
(2002)
Brain
, vol.125
, pp. 538-550
-
-
Jacobsen, M.1
Cepok, S.2
Quak, E.3
Happel, M.4
Gaber, R.5
Ziegler, A.6
Schock, S.7
Oertel, W.H.8
Sommer, N.9
Hemmer, B.10
-
18
-
-
0035932949
-
CD8(+) T cells control the TH phenotype of MBP-reactive CD4(+) T cells in EAE mice
-
Jiang H., Braunstein N.S., Yu B., Winchester R., and Chess L. CD8(+) T cells control the TH phenotype of MBP-reactive CD4(+) T cells in EAE mice. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 6301-6306
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 6301-6306
-
-
Jiang, H.1
Braunstein, N.S.2
Yu, B.3
Winchester, R.4
Chess, L.5
-
19
-
-
0026647293
-
Role of CD8(+) T cells in murine experimental allergic encephalomyelitis
-
Jiang H., Zhang S., and Pernis B. Role of CD8(+) T cells in murine experimental allergic encephalomyelitis. Science 5060 (1992) 1213-1215
-
(1992)
Science
, vol.5060
, pp. 1213-1215
-
-
Jiang, H.1
Zhang, S.2
Pernis, B.3
-
20
-
-
2442567795
-
Nonvasculitic autoimmune inflammatory meningoencephalitis
-
Josephs K.A., Rubino F.A., and Dickson D.W. Nonvasculitic autoimmune inflammatory meningoencephalitis. Neuropathology 24 (2004) 149-152
-
(2004)
Neuropathology
, vol.24
, pp. 149-152
-
-
Josephs, K.A.1
Rubino, F.A.2
Dickson, D.W.3
-
21
-
-
11844252670
-
Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN αβ and IFN γ
-
Kamath A.T., Sheasby C.E., and Tough D.F. Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN αβ and IFN γ. J. Immunol. 174 (2005) 767-776
-
(2005)
J. Immunol.
, vol.174
, pp. 767-776
-
-
Kamath, A.T.1
Sheasby, C.E.2
Tough, D.F.3
-
23
-
-
22844439662
-
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis
-
Kleinschmidt-DeMasters B.K., and Tyler K.L. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N. Engl. J. Med. 353 (2005) 369-374
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 369-374
-
-
Kleinschmidt-DeMasters, B.K.1
Tyler, K.L.2
-
24
-
-
0026694021
-
Less mortality but more relapses in experimental allergic encephalomyelitis in CD8 -/-mice
-
Koh D.R., Fung-Leung W.P., Ho A., Gray D., Acha-Orbea H., and Mak T.W. Less mortality but more relapses in experimental allergic encephalomyelitis in CD8 -/-mice. Science 5060 (1992) 1210-1213
-
(1992)
Science
, vol.5060
, pp. 1210-1213
-
-
Koh, D.R.1
Fung-Leung, W.P.2
Ho, A.3
Gray, D.4
Acha-Orbea, H.5
Mak, T.W.6
-
25
-
-
0036788406
-
Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
-
Kuhlmann T., Lingfeld G., Bitsch A., Schuchardt J., and Bruck W. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 125 (2002) 2202-2212
-
(2002)
Brain
, vol.125
, pp. 2202-2212
-
-
Kuhlmann, T.1
Lingfeld, G.2
Bitsch, A.3
Schuchardt, J.4
Bruck, W.5
-
26
-
-
0028102655
-
High incidence of spontaneous autoimmune encephalomyelitis in immune deficient anti-myelin basic protein T cell receptor transgenic mice
-
Lafaille J.J., Nagashima K., Katsuki M., and Tonegawa S. High incidence of spontaneous autoimmune encephalomyelitis in immune deficient anti-myelin basic protein T cell receptor transgenic mice. Cell 78 (1994) 399-408
-
(1994)
Cell
, vol.78
, pp. 399-408
-
-
Lafaille, J.J.1
Nagashima, K.2
Katsuki, M.3
Tonegawa, S.4
-
27
-
-
22844445230
-
Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
-
Langer-Gould A., Atlas S.W., Green A.J., Bollen A.W., and Pelletier D. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N. Engl. J. Med. 353 (2005) 375-381
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 375-381
-
-
Langer-Gould, A.1
Atlas, S.W.2
Green, A.J.3
Bollen, A.W.4
Pelletier, D.5
-
28
-
-
0342906187
-
Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination
-
Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M., and Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann. Neurol. 47 (2000) 707-717
-
(2000)
Ann. Neurol.
, vol.47
, pp. 707-717
-
-
Lucchinetti, C.1
Bruck, W.2
Parisi, J.3
Scheithauer, B.4
Rodriguez, M.5
Lassmann, H.6
-
29
-
-
0023628580
-
T cell subsets in multiple sclerosis. Gradients at plaque borders and differences in nonplaque regions
-
McCallum K., Esiri M., Tourtellotte W., and Booss J. T cell subsets in multiple sclerosis. Gradients at plaque borders and differences in nonplaque regions. Brain 110 (1987) 1297-1308
-
(1987)
Brain
, vol.110
, pp. 1297-1308
-
-
McCallum, K.1
Esiri, M.2
Tourtellotte, W.3
Booss, J.4
-
30
-
-
0037413467
-
A controlled trial of natalizumab for relapsing multiple sclerosis
-
the International Natalizumab Multiple Sclerosis Trial Group
-
Miller D.H., Khan O.A., Sheremata W.A., Blumhardt L.D., Rice G.P., Libonati M., Wilmer A.J., Hulme C.M., Dalton K.A., Mizkiel P.W., O'Connor, and the International Natalizumab Multiple Sclerosis Trial Group. A controlled trial of natalizumab for relapsing multiple sclerosis. New Engl. J. Med. 348 (2003) 15-23
-
(2003)
New Engl. J. Med.
, vol.348
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
Blumhardt, L.D.4
Rice, G.P.5
Libonati, M.6
Wilmer, A.J.7
Hulme, C.M.8
Dalton, K.A.9
Mizkiel, P.W.10
O'Connor11
-
31
-
-
0023126661
-
Exacerbations of multiple sclerosis patients treated with gamma interferon
-
Panitch H.S., Hirsch R.L., Haley A.S., and Johnson K.P. Exacerbations of multiple sclerosis patients treated with gamma interferon. Lancet 18 (1987) 893-895
-
(1987)
Lancet
, vol.18
, pp. 893-895
-
-
Panitch, H.S.1
Hirsch, R.L.2
Haley, A.S.3
Johnson, K.P.4
-
32
-
-
0037352976
-
Turnover of memory-phenotype CD8 T cells
-
Sprent J. Turnover of memory-phenotype CD8 T cells. Microbes Infect. 5 (2003) 227-231
-
(2003)
Microbes Infect.
, vol.5
, pp. 227-231
-
-
Sprent, J.1
-
33
-
-
0035877190
-
Myelin antigen-specific CD8(+) T cells are encephalitogenic and produce severe disease in C57BL/6 mice
-
Sun D., Whitaker J.N., Huang Z., Liu D., Coleclough C., Wekerle H., and Raine C.S. Myelin antigen-specific CD8(+) T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J. Immunol. 166 (2001) 7579-7587
-
(2001)
J. Immunol.
, vol.166
, pp. 7579-7587
-
-
Sun, D.1
Whitaker, J.N.2
Huang, Z.3
Liu, D.4
Coleclough, C.5
Wekerle, H.6
Raine, C.S.7
-
34
-
-
0030911461
-
Primary progressive multiple sclerosis
-
Thompson A.J., Polman C.H., Miller D.H., McDonald W.I., Brochet B., Filippi M., Montalban X., and De Sa J. Primary progressive multiple sclerosis. Brain 120 (1997) 1085-1096
-
(1997)
Brain
, vol.120
, pp. 1085-1096
-
-
Thompson, A.J.1
Polman, C.H.2
Miller, D.H.3
McDonald, W.I.4
Brochet, B.5
Filippi, M.6
Montalban, X.7
De Sa, J.8
-
35
-
-
0030918819
-
T cell stimulation in vivo by lipopolysaccharide
-
Tough D.F., Sun S., and Sprent J. T cell stimulation in vivo by lipopolysaccharide. J. Exp. Med. 185 (1997) 2089-2094
-
(1997)
J. Exp. Med.
, vol.185
, pp. 2089-2094
-
-
Tough, D.F.1
Sun, S.2
Sprent, J.3
-
36
-
-
0034162486
-
IFN-γ shapes immune invasion of the central nervous system via regulation of chemokines
-
Tran E.H., Prince E.N., and Owens T. IFN-γ shapes immune invasion of the central nervous system via regulation of chemokines. J. Immunol. 164 (2000) 2759-2768
-
(2000)
J. Immunol.
, vol.164
, pp. 2759-2768
-
-
Tran, E.H.1
Prince, E.N.2
Owens, T.3
-
37
-
-
22844445587
-
Progressive multifocal leukoencephalopathy after natalizumab treatment for Crohn's disease
-
Van Assche G., Van Ranst M., Sciot R., et al. Progressive multifocal leukoencephalopathy after natalizumab treatment for Crohn's disease. N. Engl. J. Med. 353 (2005) 362-368
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 362-368
-
-
Van Assche, G.1
Van Ranst, M.2
Sciot, R.3
-
38
-
-
0030880011
-
Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial
-
Van Oosten B.W., Lai M., Hodkinson S., Barkhof F., Miller D.H., Moseley I.F., Thompson A.J., Rudge P., McDougall A., McLeod J.G., Adler H.J., and Polman C.H. Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial. Neurology 49 (1997) 351-357
-
(1997)
Neurology
, vol.49
, pp. 351-357
-
-
Van Oosten, B.W.1
Lai, M.2
Hodkinson, S.3
Barkhof, F.4
Miller, D.H.5
Moseley, I.F.6
Thompson, A.J.7
Rudge, P.8
McDougall, A.9
McLeod, J.G.10
Adler, H.J.11
Polman, C.H.12
-
39
-
-
0028928973
-
The natural history of multiple sclerosis
-
Weinshenker B.G. The natural history of multiple sclerosis. Neurol. Clin. 13 (1995) 119-146
-
(1995)
Neurol. Clin.
, vol.13
, pp. 119-146
-
-
Weinshenker, B.G.1
-
40
-
-
0024796845
-
The natural history of multiple sclerosis: a geographically based study. 2. Predicitve value of the early clinical course
-
Weinshenker B.G., Bass B., Rice G.P., Noseworthy J., Carriere W., Baskerville J., and Ebers G.C. The natural history of multiple sclerosis: a geographically based study. 2. Predicitve value of the early clinical course. Brain 112 (1989) 1419-1428
-
(1989)
Brain
, vol.112
, pp. 1419-1428
-
-
Weinshenker, B.G.1
Bass, B.2
Rice, G.P.3
Noseworthy, J.4
Carriere, W.5
Baskerville, J.6
Ebers, G.C.7
-
41
-
-
12444329705
-
IFN-γ determines distinct clinical outcomes in autoimmune encephalomyelitis
-
Wensky A.K., Furtado G.C., Garibaldi-Marconedes M.C., Chen S., Manfra D., Lifra S.A., Zagzag D., and Lafaille J.J. IFN-γ determines distinct clinical outcomes in autoimmune encephalomyelitis. J. Immunol. 174 (2005) 1416-1423
-
(2005)
J. Immunol.
, vol.174
, pp. 1416-1423
-
-
Wensky, A.K.1
Furtado, G.C.2
Garibaldi-Marconedes, M.C.3
Chen, S.4
Manfra, D.5
Lifra, S.A.6
Zagzag, D.7
Lafaille, J.J.8
-
42
-
-
0030587910
-
IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
Willenborg D.O., Fordham S., Bernard C.C., Cowden W.B., and Ramshaw I.A. IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157 (1996) 3223-3227
-
(1996)
J. Immunol.
, vol.157
, pp. 3223-3227
-
-
Willenborg, D.O.1
Fordham, S.2
Bernard, C.C.3
Cowden, W.B.4
Ramshaw, I.A.5
-
43
-
-
0025246367
-
The T lymphocyte in experimental allergic encephalomyelitis
-
Zamvil S., and Steinman L. The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8 (1990) 579-621
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 579-621
-
-
Zamvil, S.1
Steinman, L.2
|