An Ethanolic Extract of Lindera obtusiloba Stems, YJP-14, Improves Endothelial Dysfunction, Metabolic Parameters and Physical Performance in Diabetic db/db Mice

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Lee, Jung Ok ^a,b   Auger, Cyril ^a   Park, Dong Hyun ^c   Kang, Moonkyu ^b   Oak, Min Ho ^d   Kim, Kyoung Rak ^b   Schini Kerth, Valérie B ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Hanwha Corporation   (South Korea)

^c Research Center   (South Korea)

^d Mokpo National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ALBUMIN; ALCOHOL; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CREATININE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; LINDERA OBTUSILOBA EXTRACT; PEROXYNITRITE; PIOGLITAZONE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; NOS3 PROTEIN, MOUSE; PROSTAGLANDIN SYNTHASE;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; ENZYME INHIBITION; EXERCISE TOLERANCE; EXPERIMENTAL MODEL; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; LINDERA; LINDERA OBTUSILOBA; MALE; METABOLIC PARAMETERS; MICROALBUMINURIA; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PHYSICAL PERFORMANCE; PROTEIN EXPRESSION; TREATMENT DURATION; TREATMENT OUTCOME; VASCULAR RING; VASOCONSTRICTION; VASODILATATION; WEIGHT REDUCTION; ANIMAL; AORTA; BODY WEIGHT; CHEMISTRY; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; PATHOPHYSIOLOGY; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM;

LINDERA OBTUSILOBA; MUS;

ALBUMINURIA; ANGIOTENSIN II; ANIMALS; AORTA; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; ETHANOL; EXERCISE TOLERANCE; GENE EXPRESSION; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; LINDERA; MALE; MICE; MICE, TRANSGENIC; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE III; PLANT EXTRACTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTOR, ANGIOTENSIN, TYPE 1; THIAZOLIDINEDIONES;

EID: 84878659842     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065227     Document Type: Article

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