Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression

Chemico-Biological Interactions

Volumn 192, Issue 3, 2011, Pages 233-242

  Alhaider, Abdulqader A ^a   Korashy, Hesham M ^a   Sayed Ahmed, Mohamed M ^a   Mobark, Mohammed ^b   Kfoury, Hala ^b   Mansour, Mahmoud A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

ATP AMP ratio; Diabetic nephropathy; Metformin; Oxidative stress genes; Pro inflammatory genes; Streptozotocin

Indexed keywords

ACETYL COENZYME A; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CATALASE; GLUCOSE; GLUTATHIONE TRANSFERASE ALPHA; INTERLEUKIN 6; MESSENGER RNA; METFORMIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUTATHIONE; HYPOGLYCEMIC AGENTS; KIDNEY; METFORMIN; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 79957660441     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.03.014     Document Type: Article

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