Tumor Necrosis Factor-α Promotes Cholestasis-Induced Liver Fibrosis in the Mouse through Tissue Inhibitor of Metalloproteinase-1 Production in Hepatic Stellate Cells

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Osawa, Yosuke ^a   Hoshi, Masato ^b   Yasuda, Ichiro ^a   Saibara, Toshiji ^c   Moriwaki, Hisataka ^a   Kozawa, Osamu ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; COLLAGEN TYPE I, ALPHA 1 CHAIN; TIMP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CELL INFILTRATION; CELL ISOLATION; CHOLESTASIS; CONTROLLED STUDY; CYSTIC DUCT; ENZYME SYNTHESIS; GENE EXPRESSION; INFLAMMATORY CELL; LIVER FIBROSIS; LIVER INJURY; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RAT; STELLATE CELL; TRANSCRIPTION REGULATION; TUMOR NECROSIS FACTOR ALPHA BLOOD LEVEL; ANIMAL; C57BL MOUSE; COMMON BILE DUCT; COMPLICATION; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY; WISTAR RAT;

MUS; RATTUS;

ACTINS; ANIMALS; CHOLESTASIS; COLLAGEN TYPE I; COMMON BILE DUCT; CYSTIC DUCT; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RATS; RATS, WISTAR; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878641742     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065251     Document Type: Article

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