-
2
-
-
0037160968
-
Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (life): A randomised trial against atenolol
-
Dahlof B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (life): A randomised trial against atenolol. Lancet 2002; 359: 995-1003.
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlof, B.1
Devereux, R.B.2
Kjeldsen, S.E.3
-
3
-
-
10744221128
-
The impact of serum uric acid on cardiovascular outcomes in the life study
-
Hoieggen A, Alderman MH, Kjeldsen SE, et al. The impact of serum uric acid on cardiovascular outcomes in the life study. Kidney Int 2004; 65: 1041-9.
-
(2004)
Kidney Int
, vol.65
, pp. 1041-1049
-
-
Hoieggen, A.1
Alderman, M.H.2
Kjeldsen, S.E.3
-
4
-
-
0028926576
-
Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms
-
Noda K, Saad Y, Kinoshita A, et al. Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms. J Biol Chem 1995; 270: 2284-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 2284-2289
-
-
Noda, K.1
Saad, Y.2
Kinoshita, A.3
-
5
-
-
0028977998
-
The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism
-
Feng YH, Noda K, Saad Y, Liu XP, Husain A, Karnik SS. The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism. J Biol Chem 1995; 270: 12846-50.
-
(1995)
J Biol Chem
, vol.270
, pp. 12846-12850
-
-
Feng, Y.H.1
Noda, K.2
Saad, Y.3
Liu, X.P.4
Husain, A.5
Karnik, S.S.6
-
6
-
-
0028973086
-
Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation
-
Noda K, Saad Y, Karnik SS. Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation. J Biol Chem 1995; 270: 28511-4.
-
(1995)
J Biol Chem
, vol.270
, pp. 28511-28514
-
-
Noda, K.1
Saad, Y.2
Karnik, S.S.3
-
7
-
-
0032506041
-
Mechanism of constitutive activation of the AT1 receptor: Influence of the size of the agonist switch binding residue Asn(111)
-
Feng YH, Miura S, Husain A, Karnik SS. Mechanism of constitutive activation of the AT1 receptor: Influence of the size of the agonist switch binding residue Asn(111). Biochemistry 1998; 37: 15791-8.
-
(1998)
Biochemistry
, vol.37
, pp. 15791-15798
-
-
Feng, Y.H.1
Miura, S.2
Husain, A.3
Karnik, S.S.4
-
8
-
-
0033548623
-
Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor
-
Miura S, Feng YH, Husain A, Karnik SS. Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor. J Biol Chem 1999; 274: 7103-10.
-
(1999)
J Biol Chem
, vol.274
, pp. 7103-7110
-
-
Miura, S.1
Feng, Y.H.2
Husain, A.3
Karnik, S.S.4
-
9
-
-
0027208070
-
Angiotensin II receptors and angiotensin II receptor antagonists
-
Timmermans PB, Wong PC, Chiu AT, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993; 45: 205-51.
-
(1993)
Pharmacol Rev
, vol.45
, pp. 205-251
-
-
Timmermans, P.B.1
Wong, P.C.2
Chiu, A.T.3
-
10
-
-
84878627772
-
Unique binding behavior of the recently approved angiotensin II receptor blocker azilsartan compared to that of candesartan
-
(in press)
-
Miura S, Okabe A, Matsuo Y, Karnik SS, Saku K. Unique binding behavior of the recently approved angiotensin II receptor blocker azilsartan compared to that of candesartan. Hypertens Res 2012. (in press)
-
(2012)
Hypertens Res
-
-
Miura, S.1
Okabe, A.2
Matsuo, Y.3
Karnik, S.S.4
Saku, K.5
-
11
-
-
0027972636
-
A noncompetitive type of angiotensin-receptor antagonism by losartan in renal artery preparations
-
Zhang J, Pfaffendorf M, Zhang JS, Van Zwieten PA. A noncompetitive type of angiotensin-receptor antagonism by losartan in renal artery preparations. Eur J Pharmacol 1994; 252: 337-40.
-
(1994)
Eur J Pharmacol
, vol.252
, pp. 337-340
-
-
Zhang, J.1
Pfaffendorf, M.2
Zhang, J.S.3
van Zwieten, P.A.4
-
12
-
-
82855179445
-
Azilsartan medoxomil: A new angiotensin receptor blocker
-
Zaiken K, Cheng JW. Azilsartan medoxomil: A new angiotensin receptor blocker. Clin Ther 2011; 33: 1577-89.
-
(2011)
Clin Ther
, vol.33
, pp. 1577-1589
-
-
Zaiken, K.1
Cheng, J.W.2
-
13
-
-
78751695253
-
Use of angiotensin receptor blockers in cardiovascular protection: Current evidence and future directions
-
Munger MA. Use of angiotensin receptor blockers in cardiovascular protection: Current evidence and future directions. P T 2011; 36: 22-40.
-
(2011)
P T
, vol.36
, pp. 22-40
-
-
Munger, M.A.1
-
14
-
-
84857867886
-
Efficacy and safety of angiotensin II type 1 receptor blocker/calcium channel blocker combination therapy: Focus on a single-pill fixed-dose combination of valsartan/amlodipine
-
Miura S, Saku K. Efficacy and safety of angiotensin II type 1 receptor blocker/calcium channel blocker combination therapy: focus on a single-pill fixed-dose combination of valsartan/amlodipine. J Int Med Res 2012; 40: 1-9.
-
(2012)
J Int Med Res
, vol.40
, pp. 1-9
-
-
Miura, S.1
Saku, K.2
-
15
-
-
3843140495
-
Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade
-
Awad AS, Webb RL, Carey RM, Siragy HM. Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade. J Hypertens 2004; 22: 1571-7.
-
(2004)
J Hypertens
, vol.22
, pp. 1571-1577
-
-
Awad, A.S.1
Webb, R.L.2
Carey, R.M.3
Siragy, H.M.4
-
16
-
-
79952564650
-
Angiotensin II type 1 receptor blockers: Class effects vs. Molecular effects
-
Miura S, Karnik SS, Saku K. Angiotensin II type 1 receptor blockers: Class effects vs. Molecular effects. J Renin Angiotensin Aldosterone Syst 2011; 12: 1-7.
-
(2011)
J Renin Angiotensin Aldosterone Syst
, vol.12
, pp. 1-7
-
-
Miura, S.1
Karnik, S.S.2
Saku, K.3
-
17
-
-
33745844039
-
Proposal of a new binding orientation for non-peptide AT1 antagonists: Homology modeling, docking and three-dimensional quantitative structure-activity relationship analysis
-
Tuccinardi T, Calderone V, Rapposelli S, Martinelli A. Proposal of a new binding orientation for non-peptide AT1 antagonists: Homology modeling, docking and three-dimensional quantitative structure-activity relationship analysis. J Med Chem 2006; 49: 4305-16.
-
(2006)
J Med Chem
, vol.49
, pp. 4305-4316
-
-
Tuccinardi, T.1
Calderone, V.2
Rapposelli, S.3
Martinelli, A.4
-
18
-
-
77957699101
-
1receptordependent and-independent beneficial effects
-
1receptordependent and-independent beneficial effects. Hypertens Res 2010; 33: 1044-52.
-
(2010)
Hypertens Res
, vol.33
, pp. 1044-1052
-
-
Fujino, M.1
Miura, S.2
Kiya, Y.3
-
19
-
-
38049049272
-
Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state
-
Miura S, Kiya Y, Kanazawa T, et al. Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state. Mol Endocrinol 2008; 22: 139-46.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 139-146
-
-
Miura, S.1
Kiya, Y.2
Kanazawa, T.3
-
20
-
-
0036033424
-
Constitutive activity of G-proteincoupled receptors: Cause of disease and common property of wildtype receptors
-
Seifert R, Wenzel-Seifert K. Constitutive activity of G-proteincoupled receptors: Cause of disease and common property of wildtype receptors. Naunyn Schmiedebergs Arch Pharmacol 2002; 366: 381-416.
-
(2002)
Naunyn Schmiedebergs Arch Pharmacol
, vol.366
, pp. 381-416
-
-
Seifert, R.1
Wenzel-Seifert, K.2
-
21
-
-
0029963793
-
Defects in G protein-coupled signal transduction in human disease
-
Spiegel AM. Defects in G protein-coupled signal transduction in human disease. Annu Rev Physiol 1996; 58: 143-70.
-
(1996)
Annu Rev Physiol
, vol.58
, pp. 143-170
-
-
Spiegel, A.M.1
-
22
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma J, Duprez L, Van Sande J, et al. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 1993; 365: 649-51.
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
van Sande, J.3
-
23
-
-
84857635779
-
Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice
-
Yasuda N, Akazawa H, Ito K, et al. Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice. Hypertension 2012; 59: 627-33.
-
(2012)
Hypertension
, vol.59
, pp. 627-633
-
-
Yasuda, N.1
Akazawa, H.2
Ito, K.3
-
24
-
-
10144227762
-
Mechanical stretch induces enhanced expression of angiotensin II receptor subtypes in neonatal rat cardiac myocytes
-
Kijima K, Matsubara H, Murasawa S, et al. Mechanical stretch induces enhanced expression of angiotensin II receptor subtypes in neonatal rat cardiac myocytes. Circ Res 1996; 79: 887-97.
-
(1996)
Circ Res
, vol.79
, pp. 887-897
-
-
Kijima, K.1
Matsubara, H.2
Murasawa, S.3
-
25
-
-
17644375558
-
Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: Reversal by angiotensin II type 1 receptor blockade
-
Xu ZG, Lanting L, Vaziri ND, et al. Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade. Circulation 2005; 111: 1962-9.
-
(2005)
Circulation
, vol.111
, pp. 1962-1969
-
-
Xu, Z.G.1
Lanting, L.2
Vaziri, N.D.3
-
26
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K, Kumasaka T, Hori T, et al. Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000; 289: 739-45.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
-
27
-
-
52949102889
-
Crystal structure of opsin in its G-protein-interacting conformation
-
Scheerer P, Park JH, Hildebrand PW, et al. Crystal structure of opsin in its G-protein-interacting conformation. Nature 2008; 455: 497-502.
-
(2008)
Nature
, vol.455
, pp. 497-502
-
-
Scheerer, P.1
Park, J.H.2
Hildebrand, P.W.3
-
28
-
-
47049130668
-
Crystal structure of the ligand-free G-protein-coupled receptor opsin
-
Park JH, Scheerer P, Hofmann KP, Choe HW, Ernst OP. Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 2008; 454: 183-7.
-
(2008)
Nature
, vol.454
, pp. 183-187
-
-
Park, J.H.1
Scheerer, P.2
Hofmann, K.P.3
Choe, H.W.4
Ernst, O.P.5
-
29
-
-
36448995359
-
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor
-
Cherezov V, Rosenbaum DM, Hanson MA, et al. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 2007; 318: 1258-65.
-
(2007)
Science
, vol.318
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
-
30
-
-
36448978229
-
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
-
Rosenbaum DM, Cherezov V, Hanson MA, et al. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science 2007; 318: 1266-73.
-
(2007)
Science
, vol.318
, pp. 1266-1273
-
-
Rosenbaum, D.M.1
Cherezov, V.2
Hanson, M.A.3
-
31
-
-
78651399683
-
Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
-
Rosenbaum DM, Zhang C, Lyons JA, et al. Structure and function of an irreversible agonist-beta(2) adrenoceptor complex. Nature 2011; 469: 236-40.
-
(2011)
Nature
, vol.469
, pp. 236-240
-
-
Rosenbaum, D.M.1
Zhang, C.2
Lyons, J.A.3
-
32
-
-
78651411166
-
Structure of a nanobodystabilized active state of the beta(2) adrenoceptor
-
Rasmussen SG, Choi HJ, Fung JJ, et al. Structure of a nanobodystabilized active state of the beta(2) adrenoceptor. Nature 2011; 469: 175-80.
-
(2011)
Nature
, vol.469
, pp. 175-180
-
-
Rasmussen, S.G.1
Choi, H.J.2
Fung, J.J.3
-
33
-
-
78651405537
-
The structural basis for agonist and partial agonist action on a beta(1)-adrenergic receptor
-
Warne T, Moukhametzianov R, Baker JG, et al. The structural basis for agonist and partial agonist action on a beta(1)-adrenergic receptor. Nature 2011; 469: 241-4.
-
(2011)
Nature
, vol.469
, pp. 241-244
-
-
Warne, T.1
Moukhametzianov, R.2
Baker, J.G.3
-
34
-
-
10944268709
-
Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis
-
Martin SS, Boucard AA, Clement M, Escher E, Leduc R, Guillemette G. Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis. J Biol Chem 2004; 279: 51415-23.
-
(2004)
J Biol Chem
, vol.279
, pp. 51415-51423
-
-
Martin, S.S.1
Boucard, A.A.2
Clement, M.3
Escher, E.4
Leduc, R.5
Guillemette, G.6
-
35
-
-
84862249834
-
Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor
-
Miura S, Kiya Y, Hanzawa H, et al. Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor. PLoS One 2012; 7: e37974.
-
(2012)
PLoS One
, vol.7
-
-
Miura, S.1
Kiya, Y.2
Hanzawa, H.3
-
36
-
-
2942751868
-
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
-
Zou Y, Akazawa H, Qin Y, et al. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 2004; 6: 499-506.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 499-506
-
-
Zou, Y.1
Akazawa, H.2
Qin, Y.3
-
37
-
-
62949206286
-
Mechanisms and functions of agonist-independent activation in the angiotensin II type 1 receptor
-
Akazawa H, Yasuda N, Komuro I. Mechanisms and functions of agonist-independent activation in the angiotensin II type 1 receptor. Mol Cell Endocrinol 2009; 302: 140-7.
-
(2009)
Mol Cell Endocrinol
, vol.302
, pp. 140-147
-
-
Akazawa, H.1
Yasuda, N.2
Komuro, I.3
-
38
-
-
0027460744
-
Control of cardiac gene expression by mechanical stress
-
Komuro I, Yazaki Y. Control of cardiac gene expression by mechanical stress. Annu Rev Physiol 1993; 55: 55-75.
-
(1993)
Annu Rev Physiol
, vol.55
, pp. 55-75
-
-
Komuro, I.1
Yazaki, Y.2
-
39
-
-
0032983409
-
Interaction of angiotensin II and mechanical stretch on vascular endothelial growth factor production by human mesangial cells
-
Gruden G, Thomas S, Burt D, et al. Interaction of angiotensin II and mechanical stretch on vascular endothelial growth factor production by human mesangial cells. J Am Soc Nephrol 1999; 10: 730-7.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 730-737
-
-
Gruden, G.1
Thomas, S.2
Burt, D.3
-
40
-
-
33645837015
-
Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy
-
Ogawa S, Mori T, Nako K, Kato T, Takeuchi K, Ito S. Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy. Hypertension 2006; 47: 699-705.
-
(2006)
Hypertension
, vol.47
, pp. 699-705
-
-
Ogawa, S.1
Mori, T.2
Nako, K.3
Kato, T.4
Takeuchi, K.5
Ito, S.6
-
41
-
-
40949119482
-
Anti-inflammatory and anti-oxidant properties of telmisartan in cultured human umbilical vein endothelial cells
-
Cianchetti S, Del Fiorentino A, Colognato R, Di Stefano R, Franzoni F, Pedrinelli R. Anti-inflammatory and anti-oxidant properties of telmisartan in cultured human umbilical vein endothelial cells. Atherosclerosis 2008; 198: 22-8.
-
(2008)
Atherosclerosis
, vol.198
, pp. 22-28
-
-
Cianchetti, S.1
Del Fiorentino, A.2
Colognato, R.3
Di Stefano, R.4
Franzoni, F.5
Pedrinelli, R.6
-
42
-
-
25844490022
-
Significance of angiotensinII receptor blocker lipophilicities and their protective effect against vascular remodeling
-
Takai S, Kirimura K, Jin D, et al. Significance of angiotensinII receptor blocker lipophilicities and their protective effect against vascular remodeling. Hypertens Res 2005; 28: 593-600.
-
(2005)
Hypertens Res
, vol.28
, pp. 593-600
-
-
Takai, S.1
Kirimura, K.2
Jin, D.3
-
43
-
-
0038476580
-
Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1
-
Proudfoot JM, Croft KD, Puddey IB, Beilin LJ. Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1. J Pharmacol Exp Ther 2003; 305: 846-53.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 846-853
-
-
Proudfoot, J.M.1
Croft, K.D.2
Puddey, I.B.3
Beilin, L.J.4
-
44
-
-
33646267669
-
Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b
-
Marshall TG, Lee RE, Marshall FE. Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b. Theor Biol Med Model 2006; 3: 1.
-
(2006)
Theor Biol Med Model
, vol.3
, pp. 1
-
-
Marshall, T.G.1
Lee, R.E.2
Marshall, F.E.3
-
45
-
-
0036535361
-
Uric acid and cardiovascular risk
-
Alderman MH. Uric acid and cardiovascular risk. Curr Opin Pharmacol 2002; 2: 126-30.
-
(2002)
Curr Opin Pharmacol
, vol.2
, pp. 126-130
-
-
Alderman, M.H.1
-
47
-
-
33845887252
-
Concentrationdependent mode of interaction of angiotensin II receptor blockers with uric acid transporter
-
Iwanaga T, Sato M, Maeda T, Ogihara T, Tamai I. Concentrationdependent mode of interaction of angiotensin II receptor blockers with uric acid transporter. J Pharmacol Exp Ther 2007; 320: 211-7.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 211-217
-
-
Iwanaga, T.1
Sato, M.2
Maeda, T.3
Ogihara, T.4
Tamai, I.5
-
48
-
-
84864864825
-
PPAR-γ as a therapeutic target in cardiovascular disease: Evidence and uncertainty: Thematic Review Series: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases
-
Huang JV, Greyson CR, Schwartz GG. PPAR-γ as a therapeutic target in cardiovascular disease: evidence and uncertainty: Thematic Review Series: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases. J Lipid Res 2012; 53: 1738-54.
-
(2012)
J Lipid Res
, vol.53
, pp. 1738-1754
-
-
Huang, J.V.1
Greyson, C.R.2
Schwartz, G.G.3
-
49
-
-
2442451618
-
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity
-
Schupp M, Janke J, Clasen R, Unger T, Kintscher U. Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation 2004; 109: 2054-7.
-
(2004)
Circulation
, vol.109
, pp. 2054-2057
-
-
Schupp, M.1
Janke, J.2
Clasen, R.3
Unger, T.4
Kintscher, U.5
-
50
-
-
21744452983
-
PPARgammaactivating angiotensin type-1 receptor blockers induce adiponectin
-
Clasen R, Schupp M, Foryst-Ludwig A, et al. PPARgammaactivating angiotensin type-1 receptor blockers induce adiponectin. Hypertension 2005; 46: 137-43.
-
(2005)
Hypertension
, vol.46
, pp. 137-143
-
-
Clasen, R.1
Schupp, M.2
Foryst-Ludwig, A.3
-
51
-
-
1542547460
-
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity
-
Benson SC, Pershadsingh HA, Ho CI, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension 2004; 43: 993-1002.
-
(2004)
Hypertension
, vol.43
, pp. 993-1002
-
-
Benson, S.C.1
Pershadsingh, H.A.2
Ho, C.I.3
-
52
-
-
0038818552
-
Blockade of the reninangiotensin system increases adiponectin concentrations in patients with essential hypertension
-
Furuhashi M, Ura N, Higashiura K, et al. Blockade of the reninangiotensin system increases adiponectin concentrations in patients with essential hypertension. Hypertension 2003; 42: 76-81.
-
(2003)
Hypertension
, vol.42
, pp. 76-81
-
-
Furuhashi, M.1
Ura, N.2
Higashiura, K.3
-
53
-
-
20844456215
-
Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients
-
Koh KK, Quon MJ, Han SH, et al. Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients. Circulation 2004; 110: 3687-92.
-
(2004)
Circulation
, vol.110
, pp. 3687-3692
-
-
Koh, K.K.1
Quon, M.J.2
Han, S.H.3
-
54
-
-
79952373965
-
Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
-
Haller H, Ito S, Izzo JL Jr, et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364: 907-17.
-
(2011)
N Engl J Med
, vol.364
, pp. 907-917
-
-
Haller, H.1
Ito, S.2
Izzo Jr., J.L.3
-
55
-
-
0042167336
-
Comparative effects of irbesartan on ambulatory and office blood pressure: A substudy of ambulatory blood pressure from the irbesartan in patients with type 2 diabetes and microalbuminuria study
-
Rossing K, Christensen PK, Andersen S, Hovind P, Hansen HP, Parving HH. Comparative effects of irbesartan on ambulatory and office blood pressure: A substudy of ambulatory blood pressure from the irbesartan in patients with type 2 diabetes and microalbuminuria study. Diabetes Care 2003; 26: 569-74.
-
(2003)
Diabetes Care
, vol.26
, pp. 569-574
-
-
Rossing, K.1
Christensen, P.K.2
Andersen, S.3
Hovind, P.4
Hansen, H.P.5
Parving, H.H.6
-
56
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-9.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
-
57
-
-
67649659279
-
Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: Three randomized trials
-
W3-4
-
Bilous R, Chaturvedi N, Sjolie AK, et al. Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: Three randomized trials. Ann Intern Med 2009;151:11-20, W3-4.
-
(2009)
Ann Intern Med
, vol.151
, pp. 11-20
-
-
Bilous, R.1
Chaturvedi, N.2
Sjolie, A.K.3
-
58
-
-
0034526968
-
Antiplatelet action of losartan involves TXA2 receptor antagonism but not TXA2 synthase inhibition
-
Chopicki S, Koda M, Chabielska E, Buczko W, Gryglewski RJ. Antiplatelet action of losartan involves TXA2 receptor antagonism but not TXA2 synthase inhibition. J Physiol Pharmacol 2000; 51(4 Pt 1): 715-22.
-
(2000)
J Physiol Pharmacol
, vol.51
, Issue.4 PART 1
, pp. 715-722
-
-
Chopicki, S.1
Koda, M.2
Chabielska, E.3
Buczko, W.4
Gryglewski, R.J.5
-
59
-
-
0035082059
-
Inhibition of platelet activation in stroke-prone spontaneously hypertensive rats: Comparison of losartan, candesartan, and valsartan
-
Jiménez AM, Montón M, García R, et al. Inhibition of platelet activation in stroke-prone spontaneously hypertensive rats: comparison of losartan, candesartan, and valsartan. J Cardiovasc Pharmacol 2001; 37: 406-12.
-
(2001)
J Cardiovasc Pharmacol
, vol.37
, pp. 406-412
-
-
Jiménez, A.M.1
Montón, M.2
García, R.3
-
60
-
-
0034760610
-
Comparative efficacy of olmesartan, losartan, valsartan, and irbesartan in the control of essential hypertension
-
Oparil S, Williams D, Chrysant SG, Marbury TC, Neutel J. Comparative efficacy of olmesartan, losartan, valsartan, and irbesartan in the control of essential hypertension. J Clin Hypertens (Greenwich) 2001; 3: 283-91.
-
(2001)
J Clin Hypertens (Greenwich)
, vol.3
, pp. 283-291
-
-
Oparil, S.1
Williams, D.2
Chrysant, S.G.3
Marbury, T.C.4
Neutel, J.5
-
61
-
-
0036157640
-
Efficacy of losartan, valsartan, and telmisartan in patients with mild to moderate hyper tension: A double-blind, placebo-controlled, crossover study using ambulatory blood pressure monitoring
-
Fogari R, Mugellini A, Zoppi A, Derosa G. Efficacy of losartan, valsartan, and telmisartan in patients with mild to moderate hyper tension: A double-blind, placebo-controlled, crossover study using ambulatory blood pressure monitoring. Curr Ther Res 2002; 63: 1-14.
-
(2002)
Curr Ther Res
, vol.63
, pp. 1-14
-
-
Fogari, R.1
Mugellini, A.2
Zoppi, A.3
Derosa, G.4
-
62
-
-
84860777105
-
Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: A randomized, double-blind clinical study
-
Rakugi H, Enya K, Sugiura K, Ikeda Y. Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: a randomized, double-blind clinical study. Hypertens Res 2012; 35: 552-8.
-
(2012)
Hypertens Res
, vol.35
, pp. 552-558
-
-
Rakugi, H.1
Enya, K.2
Sugiura, K.3
Ikeda, Y.4
-
63
-
-
0037079309
-
Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies
-
Prospective Studies Collaboration
-
Lewington S, Clarke R, Qizilbash N, Peto R, Collins R; Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903-13.
-
(2002)
Lancet
, vol.360
, pp. 1903-1913
-
-
Lewington, S.1
Clarke, R.2
Qizilbash, N.3
Peto, R.4
Collins, R.5
-
64
-
-
2542479913
-
Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension
-
A1410
-
Koh KK, Han SH, Chung WJ, et al. Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension. Am J Cardiol 2004; 93: 1432-5, A1410.
-
(2004)
Am J Cardiol
, vol.93
, pp. 1432-1435
-
-
Koh, K.K.1
Han, S.H.2
Chung, W.J.3
-
65
-
-
33846016634
-
Do valsartan and losartan have the same effects in the treatment of coronary artery disease?
-
Iwata A, Miura S, Imaizumi S, et al. Do valsartan and losartan have the same effects in the treatment of coronary artery disease? Circ J 2007; 71: 32-8.
-
(2007)
Circ J
, vol.71
, pp. 32-38
-
-
Iwata, A.1
Miura, S.2
Imaizumi, S.3
-
66
-
-
3343008717
-
Effects of losartan and valsartan on left ventricular hypertrophy and function in essential hypertension
-
Picca M, Agozzino F, Pelosi G. Effects of losartan and valsartan on left ventricular hypertrophy and function in essential hypertension. Adv Ther 2004; 21: 76-86.
-
(2004)
Adv Ther
, vol.21
, pp. 76-86
-
-
Picca, M.1
Agozzino, F.2
Pelosi, G.3
-
67
-
-
67650553425
-
Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation
-
Sugihara M, Miura S, Takamiya Y, et al. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertens Res 2009; 32: 625-30.
-
(2009)
Hypertens Res
, vol.32
, pp. 625-630
-
-
Sugihara, M.1
Miura, S.2
Takamiya, Y.3
-
68
-
-
76349121279
-
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension
-
Tsutamoto T, Nishiyama K, Yamaji M, et al. Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension. Hypertens Res 2010; 33: 118-22.
-
(2010)
Hypertens Res
, vol.33
, pp. 118-122
-
-
Tsutamoto, T.1
Nishiyama, K.2
Yamaji, M.3
-
69
-
-
0036895198
-
Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries
-
Pantev E, Stenman E, Wackenfors A, Edvinsson L, Malmsjo M. Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries. Eur J Heart Fail 2002; 4: 699-705.
-
(2002)
Eur J Heart Fail
, vol.4
, pp. 699-705
-
-
Pantev, E.1
Stenman, E.2
Wackenfors, A.3
Edvinsson, L.4
Malmsjo, M.5
-
70
-
-
0034878670
-
Losartan versus valsartan in the treatment of patients with mild to moderate essential hypertension: Data from a multicenter, randomized, double-blind, 12-week trial
-
Elliott WJ, Calhoun DA, DeLucca PT, Gazdick LP, Kerns DE, Zeldin RK. Losartan versus valsartan in the treatment of patients with mild to moderate essential hypertension: Data from a multicenter, randomized, double-blind, 12-week trial. Clin Ther 2001; 23: 1166-79.
-
(2001)
Clin Ther
, vol.23
, pp. 1166-1179
-
-
Elliott, W.J.1
Calhoun, D.A.2
DeLucca, P.T.3
Gazdick, L.P.4
Kerns, D.E.5
Zeldin, R.K.6
-
71
-
-
0034817415
-
Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout
-
Wurzner G, Gerster JC, Chiolero A, et al. Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout. J Hypertens 2001; 19: 1855-60.
-
(2001)
J Hypertens
, vol.19
, pp. 1855-1860
-
-
Wurzner, G.1
Gerster, J.C.2
Chiolero, A.3
-
72
-
-
44649097498
-
Telmisartan but not candesartan affects adiponectin expression in vivo and in vitro
-
Yamada S, Ano N, Toda K, et al. Telmisartan but not candesartan affects adiponectin expression in vivo and in vitro. Hypertens Res 2008; 31: 601-6.
-
(2008)
Hypertens Res
, vol.31
, pp. 601-606
-
-
Yamada, S.1
Ano, N.2
Toda, K.3
-
73
-
-
84863922737
-
Comparison of the efficacy and safety of irbesartan and olmesartan in patients with hypertension (Earth study)
-
Morii J, Miura S, Shiga Y, et al. Comparison of the efficacy and safety of irbesartan and olmesartan in patients with hypertension (Earth study). Clin Exp Hypertens 2012; 34: 342-9.
-
(2012)
Clin Exp Hypertens
, vol.34
, pp. 342-349
-
-
Morii, J.1
Miura, S.2
Shiga, Y.3
-
74
-
-
0034211530
-
Losartan inhibits in vitro platelet activation: Comparison with candesartan and valsartan
-
Núñez A, Gómez J, Zalba LR, et al. Losartan inhibits in vitro platelet activation: comparison with candesartan and valsartan. J Renin Angiotensin Aldosterone Syst 2000; 1: 175-9.
-
(2000)
J Renin Angiotensin Aldosterone Syst
, vol.1
, pp. 175-179
-
-
Núñez, A.1
Gómez, J.2
Zalba, L.R.3
-
75
-
-
34249859312
-
Platelet aggregability in patients with hypertension treated with angiotensin II type 1 receptor blockers
-
Sato Y, Fujii S, Imagawa S, et al. Platelet aggregability in patients with hypertension treated with angiotensin II type 1 receptor blockers. J Atheroscler Thromb 2007; 14: 31-5.
-
(2007)
J Atheroscler Thromb
, vol.14
, pp. 31-35
-
-
Sato, Y.1
Fujii, S.2
Imagawa, S.3
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