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Volumn 12, Issue 1, 2011, Pages 1-7

Angiotensin II type 1 receptor blockers: Class effects versus molecular effects

Author keywords

angiotensin II receptor blockers; angiotensin II type 1 receptor; class effects; common molecular structures; molecular effects

Indexed keywords

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; ADIPONECTIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; C REACTIVE PROTEIN; CANDESARTAN; CARBOXYL GROUP; CHEMOKINE RECEPTOR CCR2; ENALAPRIL; EPROSARTAN; G PROTEIN COUPLED RECEPTOR; GLUCOSE; IMIDAZOLE DERIVATIVE; INTERLEUKIN 6; INTERLEUKIN 8; IRBESARTAN; LOSARTAN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; OLMESARTAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TELMISARTAN; TUMOR NECROSIS FACTOR ALPHA; VALSARTAN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANTIINFLAMMATORY AGENT; URIC ACID;

EID: 79952564650     PISSN: 14703203     EISSN: None     Source Type: Journal    
DOI: 10.1177/1470320310370852     Document Type: Review
Times cited : (125)

References (48)
  • 1
    • 0033824138 scopus 로고    scopus 로고
    • XXIII. The angiotensin II receptors
    • International Union of Pharmacology.
    • de Gasparo M, Catt KJ, Inagami T, et al. International Union of Pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 2000; 52: 415-472.
    • (2000) Pharmacol Rev , vol.52 , pp. 415-472
    • De Gasparo, M.1    Catt, K.J.2    Inagami, T.3
  • 2
    • 33745850517 scopus 로고    scopus 로고
    • Angiotensin II receptor blocker as an inverse agonist: A current perspective
    • Miura S, Fujino M, and Saku K. Angiotensin II receptor blocker as an inverse agonist: a current perspective. Curr Hypertens Rev 2005; 1: 115-121.
    • (2005) Curr Hypertens Rev , vol.1 , pp. 115-121
    • Miura, S.1    Fujino, M.2    Saku, K.3
  • 3
    • 0028926576 scopus 로고
    • Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms
    • Noda K, Saad Y, Kinoshita A, et al. Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms. J Biol Chem 1995;270: 2284-2289.
    • (1995) J Biol Chem , vol.270 , pp. 2284-2289
    • Noda, K.1    Saad, Y.2    Kinoshita, A.3
  • 4
    • 0028977998 scopus 로고
    • The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism
    • Feng YH, Noda K, Saad Y, et al. The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism. J Biol Chem 1995; 270: 12846-12850.
    • (1995) J Biol Chem , vol.270 , pp. 12846-12850
    • Feng, Y.H.1    Noda, K.2    Saad, Y.3
  • 5
    • 0028973086 scopus 로고
    • Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation
    • DOI 10.1074/jbc.270.48.28511
    • Noda K, Saad Y, Karnik SS, et al. Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation. J Biol Chem 1995; 270: 28511-28514. (Pubitemid 3016801)
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.48 , pp. 28511-28514
    • Noda, K.1    Saad, Y.2    Karnik, S.S.3
  • 6
    • 0032506041 scopus 로고    scopus 로고
    • 111
    • DOI 10.1021/bi980863t
    • Feng, YH, Miura S, Husain A, et al. Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111). Biochemistry 1998; 37: 15791-15798. (Pubitemid 28524750)
    • (1998) Biochemistry , vol.37 , Issue.45 , pp. 15791-15798
    • Feng, Y.-H.1    Miura, S.-I.2    Husain, A.3    Karnik, S.S.4
  • 7
    • 0033548623 scopus 로고    scopus 로고
    • Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor
    • Miura S, Feng YH, Husain A, et al. Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor. J Biol Chem 1999; 274: 7103-7110.
    • (1999) J Biol Chem , vol.274 , pp. 7103-7110
    • Miura, S.1    Feng, Y.H.2    Husain, A.3
  • 9
    • 33745844039 scopus 로고    scopus 로고
    • Proposal of a new binding orientation for non-peptide AT1 antagonists: Homology modeling, docking and three-dimensional quantitative structure - Activity relationship analysis
    • DOI 10.1021/jm060338p
    • Tuccinardi T, Calderone V, Rapposelli S, and Martinelli A. Proposal of a new binding orientation for non-peptide AT1 antagonists: homology modeling, docking and three-dimensional quantitative structure-activity relationship analysis. J Med Chem 2006; 49: 4305-4316. (Pubitemid 44036674)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.14 , pp. 4305-4316
    • Tuccinardi, T.1    Calderone, V.2    Rapposelli, S.3    Martinelli, A.4
  • 10
    • 34250370923 scopus 로고    scopus 로고
    • Antihypertensive activity of angiotensin II AT1 receptor antagonists: A systematic review of studies with 24 h ambulatory blood pressure monitoring
    • DOI 10.1097/HJH.0b013e3280825625, PII 0000487220070700000003
    • Fabia MJ, Abdilla N, Oltra R, Fernandez C, and Redon J. Antihypertensive activity of angiotensin II AT1 receptor antagonists: a systematic review of studies with 24 h ambulatory blood pressure monitoring. J Hypertens 2007; 25:1327-1336. (Pubitemid 46924066)
    • (2007) Journal of Hypertension , vol.25 , Issue.7 , pp. 1327-1336
    • Fabia, M.J.1    Abdilla, N.2    Oltra, R.3    Fernandez, C.4    Redon, J.5
  • 11
    • 0034760610 scopus 로고    scopus 로고
    • Comparative efficacy of olmesartan, losartan, valsartan, and irbesartan in the control of essential hypertension
    • Oparil S, Williams D, Chrysant SG, Marbury TC, and Neutel J. Comparative efficacy of olmesartan, losartan, valsartan, and irbesartan in the control of essential hypertension. J Clin Hypertens 2001; 3: 283-291, 318.
    • (2001) J Clin Hypertens , vol.3
    • Oparil, S.1    Williams, D.2    Chrysant, S.G.3    Marbury, T.C.4    Neutel, J.5
  • 13
    • 0027972636 scopus 로고
    • A non-competitive type of angiotensin-receptor antagonism by losartan in renal artery preparations
    • Zhang J, Pfaffendorf M, Zhang JS, and Van Zwieten PA. A non-competitive type of angiotensin-receptor antagonism by losartan in renal artery preparations. Eur J Pharmaco. 1994; 252: 337-340. (Pubitemid 24053705)
    • (1994) European Journal of Pharmacology , vol.252 , Issue.3 , pp. 337-340
    • Zhang, J.1    Pfaffendorf, M.2    Zhang, J.S.3    Van Zwieten, P.A.4
  • 14
    • 0027431141 scopus 로고
    • Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- Yl]methyl]-1H-benzimidazole- 7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2′-(1Htetrazol- 5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116)
    • Shibouta Y, Inada Y, Ojima M, et al. Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H- tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole- 7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2′-(1Htetrazol- 5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole- 7-carboxylate (TCV-116). J Pharmacol Exp Ther 1993; 266: 114-120.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 114-120
    • Shibouta, Y.1    Inada, Y.2    Ojima, M.3
  • 15
    • 34547566332 scopus 로고    scopus 로고
    • 1 receptor
    • DOI 10.1038/sj.bjp.0707323, PII 0707323
    • Le MT, Pugsley MK, Vauquelin G, and Van Liefde I. Molecular characterization of the interactions between olmesartan medoxomil and telmisartan and the human angiotensin II AT1 receptor. Br J Pharmacol 2007; 151: 952-962. (Pubitemid 47195538)
    • (2007) British Journal of Pharmacology , vol.151 , Issue.7 , pp. 952-962
    • Le, M.T.1    Pugsley, M.K.2    Vauquelin, G.3    Van Liefde, I.4
  • 16
    • 0036033424 scopus 로고    scopus 로고
    • Constitutive activity of G-proteins-coupled receptors: Cause of disease and common property of wild-type receptors
    • DOI 10.1007/s00210-002-0588-0
    • Seifert R, Wenzel-Seifert K. Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors. Naunyn Schmiedebergs Arch Pharmacol 2002; 366: 381-416. (Pubitemid 35251788)
    • (2002) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.366 , Issue.5 , pp. 381-416
    • Seifert, R.1    Wenzel-Seifert, K.2
  • 17
    • 38049049272 scopus 로고    scopus 로고
    • Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state
    • Miura S, Kiya Y, Kanazawa T, et al. Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state. Mol Endocrinol 2008; 22:139-146.
    • (2008) Mol Endocrinol , vol.22 , pp. 139-146
    • Miura, S.1    Kiya, Y.2    Kanazawa, T.3
  • 23
    • 0029793195 scopus 로고    scopus 로고
    • The role of hypertension in the pathogenesis of heart failure. A clinical mechanistic overview
    • Vasan RS, Levy D. The role of hypertension in the pathogenesis of heart failure. A clinical mechanistic overview. Arch Intern Med 1996; 156: 1789-1796.
    • (1996) Arch Intern Med , vol.156 , pp. 1789-1796
    • Vasan, R.S.1    Levy, D.2
  • 24
    • 33845983222 scopus 로고    scopus 로고
    • Randomised trial of losartan versus captopril on mortality in patients with symptomatic heart failure: The losartan heart failure survival study - ELITE II
    • Pitt B, Poole-Wilson PA, Segal R, et al. Randomised trial of losartan versus captopril on mortality in patients with symptomatic heart failure: the losartan heart failure survival study - ELITE II. Lancet 2000; 355: 15822-15827.
    • (2000) Lancet , vol.355 , pp. 15822-15827
    • Pitt, B.1    Poole-Wilson, P.A.2    Segal, R.3
  • 26
    • 0030950540 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-kB activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis
    • Hernandez-Presa M, Bustos C, Ortego M, et al. Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-kB activation, monocyte chemoattractant protein-1 expression and macrophage infiltration in a rabbit model of early accelerated atherosclerosis. Circulation 1997; 95: 1532-1541. (Pubitemid 27142812)
    • (1997) Circulation , vol.95 , Issue.6 , pp. 1532-1541
    • Hernandez-Presa, M.1    Bustos, C.2    Ortego, M.3    Tunon, J.4    Renedo, G.5    Ruiz-Ortega, M.6    Egido, J.7
  • 27
    • 0038476580 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1
    • DOI 10.1124/jpet.102.047795
    • Proudfoot JM, Croft KD, Puddey IB, and Beilin LJ. Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor- stimulated human monocyte chemoattractant protein-1. J Pharmacol Exp Ther 2003; 305: 846-853. (Pubitemid 36617960)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.305 , Issue.3 , pp. 846-853
    • Proudfoot, J.M.1    Croft, K.D.2    Puddey, I.B.3    Beilin, L.J.4
  • 29
    • 33646267669 scopus 로고    scopus 로고
    • Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b
    • Marshall TG, Lee RE, and Marshall FE. Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b. Theor Biol Med Model 2006; 3: 1.
    • (2006) Theor Biol Med Model , vol.3 , pp. 1
    • Marshall, T.G.1    Lee, R.E.2    Marshall, F.E.3
  • 30
    • 3142781955 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus through inhibition of the renin-angiotensin system
    • DOI 10.2165/00003495-200464220-00004
    • Scheen AJ. Prevention of type 2 diabetes mellitus through inhibition of the Renin-Angiotensin system. Drugs 2004; 64: 2537-2565. (Pubitemid 39591650)
    • (2004) Drugs , vol.64 , Issue.22 , pp. 2537-2565
    • Scheen, A.J.1
  • 31
    • 0038818552 scopus 로고    scopus 로고
    • Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension
    • DOI 10.1161/01.HYP.0000078490.59735.6E
    • Furuhashi M, Ura N, Higashiura K, et al. Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension. Hypertension 2003; 42: 76-81. (Pubitemid 36842239)
    • (2003) Hypertension , vol.42 , Issue.1 , pp. 76-81
    • Furuhashi, M.1    Ura, N.2    Higashiura, K.3    Murakami, H.4    Tanaka, M.5    Moniwa, N.6    Yoshida, D.7    Shimamoto, K.8
  • 32
    • 20844456215 scopus 로고    scopus 로고
    • Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients
    • DOI 10.1161/01.CIR.0000143085.86697.13
    • Koh KK, Quon MJ, Han SH, et al. Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients. Circulation 2004; 110: 3687-3692. (Pubitemid 39665258)
    • (2004) Circulation , vol.110 , Issue.24 , pp. 3687-3692
    • Kwang, K.K.1    Quon, M.J.2    Seung, H.H.3    Chung, W.-J.4    Jeong, Y.A.5    Seo, Y.-H.6    Moon, H.K.7    Tae, H.A.8    In, S.C.9    Eak, K.S.10
  • 33
    • 2442451618 scopus 로고    scopus 로고
    • Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator-Activated Receptor-gamma Activity
    • DOI 10.1161/01.CIR.0000127955.36250.65
    • Schupp M, Janke J, Clasen R, Unger T, and Kintscher U. Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation 2004; 109: 2054-2057. (Pubitemid 38620211)
    • (2004) Circulation , vol.109 , Issue.17 , pp. 2054-2057
    • Schupp, M.1    Janke, J.2    Clasen, R.3    Unger, T.4    Kintscher, U.5
  • 35
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 36
    • 0035922444 scopus 로고    scopus 로고
    • The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parving HH, Lehnert H, Bröchner-Mortensen J, et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345: 870-878.
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Bröchner-Mortensen, J.3
  • 37
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 38
    • 33845887252 scopus 로고    scopus 로고
    • Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter
    • DOI 10.1124/jpet.106.112755
    • Iwanaga T, Sato M, Maeda T, Ogihara T, and Tamai I. Concentration- dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter. J Pharmacol Exp Ther 2007; 320: 211-217. (Pubitemid 46025736)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.320 , Issue.1 , pp. 211-217
    • Iwanaga, T.1    Sato, M.2    Maeda, T.3    Ogihara, T.4    Tamai, I.5
  • 39
    • 3343008717 scopus 로고    scopus 로고
    • Effects of losartan and valsartan on left ventricular hypertrophy and function in essential hypertension
    • Picca M, Agozzino F, and Pelosi G. Effects of losartan and valsartan on left ventricular hypertrophy and function in essential hypertension. Adv Ther 2004; 21: 76-86. (Pubitemid 38988471)
    • (2004) Advances in Therapy , vol.21 , Issue.2 , pp. 76-86
    • Picca, M.1    Agozzino, F.2    Pelosi, G.3
  • 42
    • 0036895198 scopus 로고    scopus 로고
    • Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries
    • DOI 10.1016/S1388-9842(02)00166-6, PII S1388984202001666
    • Pantev E, Stenman E, Wackenfors A, Edvinsson L, and Malmsjo M. Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries. Eur J Heart Fail 2002; 4: 699-705. (Pubitemid 35403077)
    • (2002) European Journal of Heart Failure , vol.4 , Issue.6 , pp. 699-705
    • Pantev, E.1    Stenman, E.2    Wackenfors, A.3    Edvinsson, L.4    Malmsjo, M.5
  • 44
    • 67650553425 scopus 로고    scopus 로고
    • Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation
    • Sugihara M, Miura S, Takamiya Y, et al. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertens Res 2009; 32: 625-630.
    • (2009) Hypertens Res , vol.32 , pp. 625-630
    • Sugihara, M.1    Miura, S.2    Takamiya, Y.3
  • 46
    • 0034211530 scopus 로고    scopus 로고
    • Losartan inhibits in vitro platelet activation: Comparison with candesartan and valsartan
    • Nunez A, Gomez J, Zalba LR, et al. Losartan inhibits in vitro platelet activation: comparison with candesartan and valsartan. J Renin Angiotensin Aldosterone Syst 2000; 1: 175-179.
    • (2000) J Renin Angiotensin Aldosterone Syst , vol.1 , pp. 175-179
    • Nunez, A.1    Gomez, J.2    Zalba, L.R.3
  • 47
    • 40149095418 scopus 로고    scopus 로고
    • Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-state type-2 diabetics with hypertension
    • DOI 10.1291/hypres.31.7
    • Nakayama S, Watada H, Mita T, et al. Comparison of effects of olmesartan and telmisartan on blood pressure and metabolic parameters in Japanese early-stage type-2 diabetics with hypertension. Hypertens Res 2008; 31: 7-13. (Pubitemid 351325609)
    • (2008) Hypertension Research , vol.31 , Issue.1 , pp. 7-13
    • Nakayama, S.1    Watada, H.2    Mita, T.3    Ikeda, F.4    Shimizu, T.5    Uchino, H.6    Fujitani, Y.7    Hirose, T.8    Kawamori, R.9
  • 48
    • 46049088895 scopus 로고    scopus 로고
    • Comparison of the effects of telmisartan and olmesartan on home blood pressure, glucose, and lipid profiles in patients with hypertension, chronic heart failure, and metabolic syndrome
    • DOI 10.1291/hypres.31.921
    • Sasaki T, Noda Y, Yasuoka Y, et al. Comparison of the effects of telmisartan and olmesartan on home blood pressure, glucose, and lipid profiles in patients with hypertension, chronic heart failure, and metabolic syndrome. Hypertens Res 2008; 31: 921-929. (Pubitemid 351895037)
    • (2008) Hypertension Research , vol.31 , Issue.5 , pp. 921-929
    • Sasaki, T.1    Noda, Y.2    Yasuoka, Y.3    Irino, H.4    Abe, H.5    Adachi, H.6    Hattori, S.7    Kitada, H.8    Morisawa, D.9    Miyatake, K.10


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