Elevated Incidence of Polyp Formation in APCMin/+Msh2-/- Mice Is Independent of Nitric Oxide-Induced DNA Mutations

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Belcheva, Antoaneta ^a   Green, Blerta ^a   Weiss, Ashley ^a   Streutker, Catherine ^b   Martin, Alberto ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; APC PROTEIN; CYTOSINE; DNA; GUANINE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROTEIN MSH2; THYMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER SUSCEPTIBILITY; CELL FUNCTION; CELL REGENERATION; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; COLON POLYP; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GENE; GENE DELETION; GENE INSERTION; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INCIDENCE; LACI GENE; MACROPHAGE; MALE; MISMATCH REPAIR; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; TUMOR PROMOTION;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; COLONIC POLYPS; DISEASE MODELS, ANIMAL; DNA MISMATCH REPAIR; FEMALE; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; MUTATION; MUTS HOMOLOG 2 PROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II;

BACTERIA (MICROORGANISMS); MUS;

EID: 84878620185     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065204     Document Type: Article

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