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Volumn 34, Issue 6, 2013, Pages 303-312

Targeting inflammation and wound healing by opioids

Author keywords

analgesia; leukocytes; pain; sensory neurons; skin

Indexed keywords

ASIMADOLINE; BETA ENDORPHIN; CALCITONIN GENE RELATED PEPTIDE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; ENDOMORPHIN 1; FENTANYL; HYDROMORPHONE; KAPPA OPIATE RECEPTOR; LOPERAMIDE; MORPHINE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NARCOTIC ANALGESIC AGENT; NEUROPEPTIDE; PROOPIOMELANOCORTIN; SUBSTANCE P; TYROSYL DEXTRO ARGINYLPHENYLALANYLLYSINAMIDE; VANILLOID RECEPTOR 1;

EID: 84878583479     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2013.03.006     Document Type: Review
Times cited : (110)

References (107)
  • 1
    • 84872130535 scopus 로고    scopus 로고
    • Anti-inflammatory therapy in chronic disease: Challenges and opportunities
    • I. Tabas, and C.K. Glass Anti-inflammatory therapy in chronic disease: challenges and opportunities Science 339 2013 166 172
    • (2013) Science , vol.339 , pp. 166-172
    • Tabas, I.1    Glass, C.K.2
  • 2
    • 78751695197 scopus 로고    scopus 로고
    • Cardiovascular safety of non-steroidal anti-inflammatory drugs: Network meta-analysis
    • S. Trelle Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis BMJ 342 2011 c7086
    • (2011) BMJ , vol.342 , pp. 7086
    • Trelle, S.1
  • 3
    • 29244466111 scopus 로고    scopus 로고
    • Adverse effects of topical glucocorticosteroids
    • U.R. Hengge Adverse effects of topical glucocorticosteroids J. Am. Acad. Dermatol. 54 2006 1 18
    • (2006) J. Am. Acad. Dermatol. , vol.54 , pp. 1-18
    • Hengge, U.R.1
  • 4
    • 44849119611 scopus 로고    scopus 로고
    • Anesthetics impact the resolution of inflammation
    • N. Chiang Anesthetics impact the resolution of inflammation PLoS ONE 3 2008 e1879
    • (2008) PLoS ONE , vol.3 , pp. 1879
    • Chiang, N.1
  • 5
    • 78049459474 scopus 로고    scopus 로고
    • Local anesthetics
    • R.D. Miller, 7th edn Churchill Livingstone Elsevier
    • C.B. Berde, and G.R. Strichartz Local anesthetics R.D. Miller, Miller's Anesthesia 7th edn 2010 Churchill Livingstone Elsevier 913 939
    • (2010) Miller's Anesthesia , pp. 913-939
    • Berde, C.B.1    Strichartz, G.R.2
  • 6
    • 84864662570 scopus 로고    scopus 로고
    • Kinase inhibition - A new approach to the treatment of rheumatoid arthritis
    • D.A. Fox Kinase inhibition - a new approach to the treatment of rheumatoid arthritis N. Engl. J. Med. 367 2012 565 567
    • (2012) N. Engl. J. Med. , vol.367 , pp. 565-567
    • Fox, D.A.1
  • 7
    • 84859862757 scopus 로고    scopus 로고
    • Updated recommendations for the treatment of rheumatoid arthritis: Another step on a long road
    • D.I. Daikh, and E.W. St Clair Updated recommendations for the treatment of rheumatoid arthritis: another step on a long road Arthritis Care Res. (Hoboken) 64 2012 648 651
    • (2012) Arthritis Care Res. (Hoboken) , vol.64 , pp. 648-651
    • Daikh, D.I.1    St Clair, E.W.2
  • 8
    • 0027512061 scopus 로고
    • Peripheral mechanisms of opioid analgesia
    • C. Stein Peripheral mechanisms of opioid analgesia Anesth. Analg. 76 1993 182 191
    • (1993) Anesth. Analg. , vol.76 , pp. 182-191
    • Stein, C.1
  • 9
    • 80053606300 scopus 로고    scopus 로고
    • Modulation of peripheral sensory neurons by the immune system: Implications for pain therapy
    • C. Stein, and H. Machelska Modulation of peripheral sensory neurons by the immune system: implications for pain therapy Pharmacol. Rev. 63 2011 860 881
    • (2011) Pharmacol. Rev. , vol.63 , pp. 860-881
    • Stein, C.1    Machelska, H.2
  • 10
    • 58049184641 scopus 로고    scopus 로고
    • Opioid receptors: From binding sites to visible molecules in vivo
    • B.L. Kieffer, and C.J. Evans Opioid receptors: from binding sites to visible molecules in vivo Neuropharmacology 56 Suppl. 1 2009 205 212
    • (2009) Neuropharmacology , vol.56 , Issue.SUPPL. 1 , pp. 205-212
    • Kieffer, B.L.1    Evans, C.J.2
  • 12
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • C.A. Moore Regulation of receptor trafficking by GRKs and arrestins Annu. Rev. Physiol. 69 2007 451 482
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 451-482
    • Moore, C.A.1
  • 13
    • 0025362849 scopus 로고
    • Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation
    • C. Stein Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation Proc. Natl. Acad. Sci. U.S.A. 87 1990 5935 5939
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 5935-5939
    • Stein, C.1
  • 14
    • 34248382512 scopus 로고    scopus 로고
    • Beta-arrestin2 and c-Src regulate the constitutive activity and recycling of mu opioid receptors in dorsal root ganglion neurons
    • W. Walwyn Beta-arrestin2 and c-Src regulate the constitutive activity and recycling of mu opioid receptors in dorsal root ganglion neurons J. Neurosci. 27 2007 5092 5104
    • (2007) J. Neurosci. , vol.27 , pp. 5092-5104
    • Walwyn, W.1
  • 15
    • 84869167187 scopus 로고    scopus 로고
    • Fentanyl decreases discharges of C and A nociceptors to suprathreshold mechanical stimulation in chronic inflammation
    • R. Moshourab, and C. Stein Fentanyl decreases discharges of C and A nociceptors to suprathreshold mechanical stimulation in chronic inflammation J. Neurophysiol. 108 2012 2827 2836
    • (2012) J. Neurophysiol. , vol.108 , pp. 2827-2836
    • Moshourab, R.1    Stein, C.2
  • 16
    • 84875412200 scopus 로고    scopus 로고
    • Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner
    • V. Spahn Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner Pain 154 2013 598 608
    • (2013) Pain , vol.154 , pp. 598-608
    • Spahn, V.1
  • 17
    • 29144445369 scopus 로고    scopus 로고
    • Multiple opioid receptors on immune cells modulate intracellular signaling
    • B.M. Sharp Multiple opioid receptors on immune cells modulate intracellular signaling Brain Behav. Immun. 20 2006 9 14
    • (2006) Brain Behav. Immun. , vol.20 , pp. 9-14
    • Sharp, B.M.1
  • 18
    • 0031904565 scopus 로고    scopus 로고
    • Expression of mu-opiate receptor in human epidermis and keratinocytes
    • P.L. Bigliardi Expression of mu-opiate receptor in human epidermis and keratinocytes J. Invest. Dermatol. 111 1998 297 301
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 297-301
    • Bigliardi, P.L.1
  • 19
    • 27744588030 scopus 로고    scopus 로고
    • Detection of kappa and delta opioid receptors in skin - Outside the nervous system
    • S. Salemi Detection of kappa and delta opioid receptors in skin - Outside the nervous system Biochem. Biophys. Res. Commun. 338 2005 1012 1017
    • (2005) Biochem. Biophys. Res. Commun. , vol.338 , pp. 1012-1017
    • Salemi, S.1
  • 20
    • 40949111413 scopus 로고    scopus 로고
    • Coexistence and upregulation of three types of opioid receptors, mu, delta and kappa, in human hypertrophic scars
    • B. Cheng Coexistence and upregulation of three types of opioid receptors, mu, delta and kappa, in human hypertrophic scars Br. J. Dermatol. 158 2008 713 720
    • (2008) Br. J. Dermatol. , vol.158 , pp. 713-720
    • Cheng, B.1
  • 21
    • 84864979830 scopus 로고    scopus 로고
    • Morphine stimulates cell migration of oral epithelial cells by delta-opioid receptor activation
    • N. Charbaji Morphine stimulates cell migration of oral epithelial cells by delta-opioid receptor activation PLoS ONE 7 2012 e42616
    • (2012) PLoS ONE , vol.7 , pp. 42616
    • Charbaji, N.1
  • 22
    • 65249154034 scopus 로고    scopus 로고
    • Opioids and the skin - Where do we stand?
    • P.L. Bigliardi Opioids and the skin - where do we stand? Exp. Dermatol. 18 2009 424 430
    • (2009) Exp. Dermatol. , vol.18 , pp. 424-430
    • Bigliardi, P.L.1
  • 23
    • 34248591810 scopus 로고    scopus 로고
    • Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior
    • M. Bigliardi-Qi Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior J. Invest. Dermatol. 127 2007 1479 1488
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 1479-1488
    • Bigliardi-Qi, M.1
  • 24
    • 77953619984 scopus 로고    scopus 로고
    • Opioid receptors and opioid peptide-producing leukocytes in inflammatory pain - Basic and therapeutic aspects
    • M. Busch-Dienstfertig, and C. Stein Opioid receptors and opioid peptide-producing leukocytes in inflammatory pain - basic and therapeutic aspects Brain Behav. Immun. 24 2010 683 694
    • (2010) Brain Behav. Immun. , vol.24 , pp. 683-694
    • Busch-Dienstfertig, M.1    Stein, C.2
  • 25
    • 84867233009 scopus 로고    scopus 로고
    • Non-analgesic effects of opioids: Peripheral opioid effects on inflammation and wound healing
    • C. Stein, and S. Küchler Non-analgesic effects of opioids: Peripheral opioid effects on inflammation and wound healing Curr. Pharm. Des. 18 2012 6053 6069
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 6053-6069
    • Stein, C.1    Küchler, S.2
  • 26
    • 84868667133 scopus 로고    scopus 로고
    • JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats
    • M. Busch-Dienstfertig JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats Mol. Pain 8 2012 83
    • (2012) Mol. Pain , vol.8 , pp. 83
    • Busch-Dienstfertig, M.1
  • 27
    • 84870341507 scopus 로고    scopus 로고
    • Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue
    • A. Schreiter Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue FASEB J. 26 2012 5161 5171
    • (2012) FASEB J. , vol.26 , pp. 5161-5171
    • Schreiter, A.1
  • 28
    • 84859324853 scopus 로고    scopus 로고
    • Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain
    • B.P. Roques Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain Nat. Rev. Drug Discov. 11 2012 292 310
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 292-310
    • Roques, B.P.1
  • 29
    • 39749119900 scopus 로고    scopus 로고
    • Morphine-6-glucuronide (M6G) for postoperative pain relief
    • A. Dahan Morphine-6-glucuronide (M6G) for postoperative pain relief Eur. J. Pain 12 2008 403 411
    • (2008) Eur. J. Pain , vol.12 , pp. 403-411
    • Dahan, A.1
  • 30
    • 60749087739 scopus 로고    scopus 로고
    • Assays to predict drug permeation across the blood-brain barrier, and distribution to brain
    • N.J. Abbott Assays to predict drug permeation across the blood-brain barrier, and distribution to brain Curr. Drug Metab. 9 2008 901 910
    • (2008) Curr. Drug Metab. , vol.9 , pp. 901-910
    • Abbott, N.J.1
  • 31
    • 0030449599 scopus 로고    scopus 로고
    • The relevance of opioids and opioid receptors on immunocompetence and immune homeostasis
    • D.J. Carr The relevance of opioids and opioid receptors on immunocompetence and immune homeostasis Proc. Soc. Exp. Biol. Med. 213 1996 248 257
    • (1996) Proc. Soc. Exp. Biol. Med. , vol.213 , pp. 248-257
    • Carr, D.J.1
  • 32
    • 0037734279 scopus 로고    scopus 로고
    • Experimental evidence for immunomodulatory effects of opioids
    • P. Sacerdote Experimental evidence for immunomodulatory effects of opioids Adv. Exp. Med. Biol. 521 2003 106 116
    • (2003) Adv. Exp. Med. Biol. , vol.521 , pp. 106-116
    • Sacerdote, P.1
  • 33
    • 81355138774 scopus 로고    scopus 로고
    • Immunosuppressive effects of opioids - Clinical relevance
    • A. Brack Immunosuppressive effects of opioids - clinical relevance J. Neuroimmune Pharmacol. 6 2011 490 502
    • (2011) J. Neuroimmune Pharmacol. , vol.6 , pp. 490-502
    • Brack, A.1
  • 34
    • 79953292900 scopus 로고    scopus 로고
    • Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism
    • H.M. Vesterinen Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism J. Cereb. Blood Flow Metab. 31 2011 1064 1072
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , pp. 1064-1072
    • Vesterinen, H.M.1
  • 35
    • 79151481510 scopus 로고    scopus 로고
    • Peripheral analgesia: Hitting pain where it hurts
    • J.J. McDougall Peripheral analgesia: Hitting pain where it hurts Biochim. Biophys. Acta 1812 2011 459 467
    • (2011) Biochim. Biophys. Acta , vol.1812 , pp. 459-467
    • McDougall, J.J.1
  • 36
    • 0028854866 scopus 로고
    • Pharmacological evidence for the involvement of the endogenous opioid system in the response to local inflammation in the rat paw
    • M.E. Planas Pharmacological evidence for the involvement of the endogenous opioid system in the response to local inflammation in the rat paw Pain 60 1995 67 71
    • (1995) Pain , vol.60 , pp. 67-71
    • Planas, M.E.1
  • 37
    • 0030570487 scopus 로고    scopus 로고
    • Involvement of beta-endorphin in the modulation of paw inflammatory edema in the rat
    • P. Sacerdote Involvement of beta-endorphin in the modulation of paw inflammatory edema in the rat Regul. Pept. 63 1996 79 83
    • (1996) Regul. Pept. , vol.63 , pp. 79-83
    • Sacerdote, P.1
  • 38
    • 15844414166 scopus 로고    scopus 로고
    • Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw
    • A. Romero Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw Eur. J. Pharmacol. 511 2005 207 217
    • (2005) Eur. J. Pharmacol. , vol.511 , pp. 207-217
    • Romero, A.1
  • 39
    • 1642363342 scopus 로고    scopus 로고
    • Attenuation of knee joint inflammation by peripherally administered endomorphin-1
    • J.J. McDougall Attenuation of knee joint inflammation by peripherally administered endomorphin-1 J. Mol. Neurosci. 22 2004 125 137
    • (2004) J. Mol. Neurosci. , vol.22 , pp. 125-137
    • McDougall, J.J.1
  • 40
    • 0032835880 scopus 로고    scopus 로고
    • Effects of intraplantar morphine on paw edema and pain-related behaviour in a rat model of repeated acute inflammation
    • S. Perrot Effects of intraplantar morphine on paw edema and pain-related behaviour in a rat model of repeated acute inflammation Pain 83 1999 249 257
    • (1999) Pain , vol.83 , pp. 249-257
    • Perrot, S.1
  • 41
    • 0024153212 scopus 로고
    • Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: Alterations in behavior and nociceptive thresholds
    • C. Stein Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds Pharmacol. Biochem. Behav. 31 1988 445 451
    • (1988) Pharmacol. Biochem. Behav. , vol.31 , pp. 445-451
    • Stein, C.1
  • 42
    • 0036066045 scopus 로고    scopus 로고
    • No pain, no gain: Clinical excellence and scientific rigour - Lessons learned from IA morphine
    • E. Kalso No pain, no gain: clinical excellence and scientific rigour - lessons learned from IA morphine Pain 98 2002 269 275
    • (2002) Pain , vol.98 , pp. 269-275
    • Kalso, E.1
  • 43
    • 79958071922 scopus 로고    scopus 로고
    • Imaging studies in Freund's complete adjuvant model of regional polyarthritis, a model suitable for the study of pain mechanisms, in the rat
    • L. Almarestani Imaging studies in Freund's complete adjuvant model of regional polyarthritis, a model suitable for the study of pain mechanisms, in the rat Arthritis Rheum. 63 2011 1573 1581
    • (2011) Arthritis Rheum. , vol.63 , pp. 1573-1581
    • Almarestani, L.1
  • 44
    • 0034985520 scopus 로고    scopus 로고
    • Analgesic and antiinflammatory effects of two novel kappa-opioid peptides
    • W. Binder Analgesic and antiinflammatory effects of two novel kappa-opioid peptides Anesthesiology 94 2001 1034 1044
    • (2001) Anesthesiology , vol.94 , pp. 1034-1044
    • Binder, W.1
  • 45
    • 77953538005 scopus 로고    scopus 로고
    • Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: Substance P role in peripheral inflammation in mice
    • V. Fernandez-Duenas Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice Eur. J. Pharmacol. 638 2010 72 77
    • (2010) Eur. J. Pharmacol. , vol.638 , pp. 72-77
    • Fernandez-Duenas, V.1
  • 46
    • 0344731442 scopus 로고    scopus 로고
    • Peripheral effects of the kappa-opioid agonist EMD 61753 on pain and inflammation in rats and humans
    • H. Machelska Peripheral effects of the kappa-opioid agonist EMD 61753 on pain and inflammation in rats and humans J. Pharmacol. Exp. Ther. 290 1999 354 361
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 354-361
    • Machelska, H.1
  • 47
    • 1642367521 scopus 로고    scopus 로고
    • Loss of vasomotor responsiveness to the mu-opioid receptor ligand endomorphin-1 in adjuvant monoarthritic rat knee joints
    • J.J. McDougall Loss of vasomotor responsiveness to the mu-opioid receptor ligand endomorphin-1 in adjuvant monoarthritic rat knee joints Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 2004 R634 R641
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.286
    • McDougall, J.J.1
  • 48
    • 64149109635 scopus 로고    scopus 로고
    • Effects of intraarticular ropivacaine and morphine on lipopolysaccharide-induced synovitis in horses
    • L.C. Santos Effects of intraarticular ropivacaine and morphine on lipopolysaccharide-induced synovitis in horses Vet. Anaesth. Analg. 36 2009 280 286
    • (2009) Vet. Anaesth. Analg. , vol.36 , pp. 280-286
    • Santos, L.C.1
  • 49
    • 75749135674 scopus 로고    scopus 로고
    • Anti-inflammatory effects of intra-articular administration of morphine in horses with experimentally induced synovitis
    • C. Lindegaard Anti-inflammatory effects of intra-articular administration of morphine in horses with experimentally induced synovitis Am. J. Vet. Res. 71 2010 69 75
    • (2010) Am. J. Vet. Res. , vol.71 , pp. 69-75
    • Lindegaard, C.1
  • 50
    • 77953864365 scopus 로고    scopus 로고
    • Intra-articular opioid analgesia is effective in reducing pain and inflammation in an equine LPS induced synovitis model
    • J.P. van Loon Intra-articular opioid analgesia is effective in reducing pain and inflammation in an equine LPS induced synovitis model Equine Vet. J. 42 2010 412 419
    • (2010) Equine Vet. J. , vol.42 , pp. 412-419
    • Van Loon, J.P.1
  • 51
    • 8544278193 scopus 로고    scopus 로고
    • Intra-articular morphine and saline injections induce release of large molecular weight proteoglycans into equine synovial fluid
    • R.M. Tulamo Intra-articular morphine and saline injections induce release of large molecular weight proteoglycans into equine synovial fluid Zentralbl. Veterinarmed. A 43 1996 147 153
    • (1996) Zentralbl. Veterinarmed. A , vol.43 , pp. 147-153
    • Tulamo, R.M.1
  • 52
    • 0036635246 scopus 로고    scopus 로고
    • The effects of morphine on human articular cartilage of the knee: An in vitro study
    • J.W. Jaureguito The effects of morphine on human articular cartilage of the knee: an in vitro study Arthroscopy 18 2002 631 636
    • (2002) Arthroscopy , vol.18 , pp. 631-636
    • Jaureguito, J.W.1
  • 53
    • 0028631463 scopus 로고
    • Proinflammatory effects of morphine in the rat adjuvant arthritis model
    • J.R. Earl Proinflammatory effects of morphine in the rat adjuvant arthritis model Int. J. Tissue React. 16 1994 163 170
    • (1994) Int. J. Tissue React. , vol.16 , pp. 163-170
    • Earl, J.R.1
  • 54
    • 0031861374 scopus 로고    scopus 로고
    • Effect of the peripherally selective kappa-opioid agonist, asimadoline, on adjuvant arthritis
    • W. Binder, and J.S. Walker Effect of the peripherally selective kappa-opioid agonist, asimadoline, on adjuvant arthritis Br. J. Pharmacol. 124 1998 647 654
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 647-654
    • Binder, W.1    Walker, J.S.2
  • 55
    • 0035887602 scopus 로고    scopus 로고
    • Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons
    • J. Braz Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons J. Neurosci. 21 2001 7881 7888
    • (2001) J. Neurosci. , vol.21 , pp. 7881-7888
    • Braz, J.1
  • 56
    • 34447526546 scopus 로고    scopus 로고
    • Amelioration of pain and histopathologic joint abnormalities in the Col1-IL-1beta(XAT) mouse model of arthritis by intraarticular induction of mu-opioid receptor into the temporomandibular joint
    • S. Kyrkanides Amelioration of pain and histopathologic joint abnormalities in the Col1-IL-1beta(XAT) mouse model of arthritis by intraarticular induction of mu-opioid receptor into the temporomandibular joint Arthritis Rheum. 56 2007 2038 2048
    • (2007) Arthritis Rheum. , vol.56 , pp. 2038-2048
    • Kyrkanides, S.1
  • 57
    • 2142768143 scopus 로고    scopus 로고
    • Expression of opioid receptors during peripheral inflammation
    • O. Pol, and M.M. Puig Expression of opioid receptors during peripheral inflammation Curr. Top. Med. Chem. 4 2004 51 61
    • (2004) Curr. Top. Med. Chem. , vol.4 , pp. 51-61
    • Pol, O.1    Puig, M.M.2
  • 58
    • 0037651166 scopus 로고    scopus 로고
    • Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation
    • D. Philippe Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation J. Clin. Invest. 111 2003 1329 1338
    • (2003) J. Clin. Invest. , vol.111 , pp. 1329-1338
    • Philippe, D.1
  • 59
    • 34347223682 scopus 로고    scopus 로고
    • Mu-Opioid receptor activation prevents acute hepatic inflammation and cell death
    • D. Chakass mu-Opioid receptor activation prevents acute hepatic inflammation and cell death Gut 56 2007 974 981
    • (2007) Gut , vol.56 , pp. 974-981
    • Chakass, D.1
  • 60
    • 34247177640 scopus 로고    scopus 로고
    • A molecular basis of analgesic tolerance to cannabinoids
    • A. Tappe-Theodor A molecular basis of analgesic tolerance to cannabinoids J. Neurosci. 27 2007 4165 4177
    • (2007) J. Neurosci. , vol.27 , pp. 4165-4177
    • Tappe-Theodor, A.1
  • 61
    • 11144346133 scopus 로고    scopus 로고
    • Management of perioperative pain in patients chronically consuming opioids
    • I.R. Carroll Management of perioperative pain in patients chronically consuming opioids Reg. Anesth. Pain Med. 29 2004 576 591
    • (2004) Reg. Anesth. Pain Med. , vol.29 , pp. 576-591
    • Carroll, I.R.1
  • 62
    • 84892575256 scopus 로고    scopus 로고
    • Opioids, sensory systems and chronic pain
    • (in press) doi:10.1016/j.ejphar.2013.01.076
    • Stein, C. (2013) Opioids, sensory systems and chronic pain. Eur. J. Pharmacol. http://dx.doi.org/10.1016/j.ejphar.2013.01.076, (in press)
    • (2013) Eur. J. Pharmacol.
    • Stein, C.1
  • 63
    • 40549105390 scopus 로고    scopus 로고
    • Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain
    • C. Zöllner Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain J. Clin. Invest. 118 2008 1065 1073
    • (2008) J. Clin. Invest. , vol.118 , pp. 1065-1073
    • Zöllner, C.1
  • 64
    • 11244344642 scopus 로고    scopus 로고
    • Receptor endocytosis counteracts the development of opioid tolerance
    • T. Koch Receptor endocytosis counteracts the development of opioid tolerance Mol. Pharmacol. 67 2005 280 287
    • (2005) Mol. Pharmacol. , vol.67 , pp. 280-287
    • Koch, T.1
  • 65
    • 0032571282 scopus 로고    scopus 로고
    • Lack of tolerance in peripheral opioid analgesia in mice
    • S. Tokuyama Lack of tolerance in peripheral opioid analgesia in mice Life Sci. 62 1998 1677 1681
    • (1998) Life Sci. , vol.62 , pp. 1677-1681
    • Tokuyama, S.1
  • 66
    • 45549083888 scopus 로고    scopus 로고
    • Clinical trial: Asimadoline in the treatment of patients with irritable bowel syndrome
    • A.W. Mangel Clinical trial: asimadoline in the treatment of patients with irritable bowel syndrome Aliment. Pharmacol. Ther. 28 2008 239 249
    • (2008) Aliment. Pharmacol. Ther. , vol.28 , pp. 239-249
    • Mangel, A.W.1
  • 67
    • 39749126240 scopus 로고    scopus 로고
    • Inhibitory action of endomorphin-1 on sensory neuropeptide release and neurogenic inflammation in rats and mice
    • R. Borzsei Inhibitory action of endomorphin-1 on sensory neuropeptide release and neurogenic inflammation in rats and mice Neuroscience 152 2008 82 88
    • (2008) Neuroscience , vol.152 , pp. 82-88
    • Borzsei, R.1
  • 68
    • 34250737357 scopus 로고    scopus 로고
    • Tolerance to the antinociceptive and antiexudative effects of morphine in a murine model of peripheral inflammation
    • V. Fernandez-Duenas Tolerance to the antinociceptive and antiexudative effects of morphine in a murine model of peripheral inflammation J. Pharmacol. Exp. Ther. 322 2007 360 368
    • (2007) J. Pharmacol. Exp. Ther. , vol.322 , pp. 360-368
    • Fernandez-Duenas, V.1
  • 69
    • 26844499513 scopus 로고    scopus 로고
    • Chronic arthritis down-regulates peripheral mu-opioid receptor expression with concomitant loss of endomorphin 1 antinociception
    • Z. Li Chronic arthritis down-regulates peripheral mu-opioid receptor expression with concomitant loss of endomorphin 1 antinociception Arthritis Rheum. 52 2005 3210 3219
    • (2005) Arthritis Rheum. , vol.52 , pp. 3210-3219
    • Li, Z.1
  • 70
    • 66749154689 scopus 로고    scopus 로고
    • Dissociation of the opioid receptor mechanisms that control mechanical and heat pain
    • G. Scherrer Dissociation of the opioid receptor mechanisms that control mechanical and heat pain Cell 137 2009 1148 1159
    • (2009) Cell , vol.137 , pp. 1148-1159
    • Scherrer, G.1
  • 71
    • 77955606622 scopus 로고    scopus 로고
    • Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons
    • H.B. Wang Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons Proc. Natl. Acad. Sci. U.S.A. 107 2010 13117 13122
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 13117-13122
    • Wang, H.B.1
  • 72
    • 43749088730 scopus 로고    scopus 로고
    • Wound repair and regeneration
    • G.C. Gurtner Wound repair and regeneration Nature 453 2008 314 321
    • (2008) Nature , vol.453 , pp. 314-321
    • Gurtner, G.C.1
  • 73
    • 0025953982 scopus 로고
    • Analgesic effect of intraarticular morphine after arthroscopic knee surgery
    • C. Stein Analgesic effect of intraarticular morphine after arthroscopic knee surgery N. Engl. J. Med. 325 1991 1123 1126
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1123-1126
    • Stein, C.1
  • 74
    • 79956206894 scopus 로고    scopus 로고
    • Should topical opioid analgesics be regarded as effective and safe when applied to chronic cutaneous lesions?
    • P. Farley Should topical opioid analgesics be regarded as effective and safe when applied to chronic cutaneous lesions? J. Pharm. Pharmacol. 63 2011 747 756
    • (2011) J. Pharm. Pharmacol. , vol.63 , pp. 747-756
    • Farley, P.1
  • 75
    • 59649122150 scopus 로고    scopus 로고
    • Nanoparticles for skin penetration enhancement - A comparison of a dendritic core-multishell-nanotransporter and solid lipid nanoparticles
    • S. Küchler Nanoparticles for skin penetration enhancement - a comparison of a dendritic core-multishell-nanotransporter and solid lipid nanoparticles Eur. J. Pharm. Biopharm. 71 2009 243 250
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 243-250
    • Küchler, S.1
  • 76
    • 0036975891 scopus 로고    scopus 로고
    • Specific stimulation of migration of human keratinocytes by mu-opiate receptor agonists
    • P.L. Bigliardi Specific stimulation of migration of human keratinocytes by mu-opiate receptor agonists J. Recept. Signal Transduct. Res. 22 2002 191 199
    • (2002) J. Recept. Signal Transduct. Res. , vol.22 , pp. 191-199
    • Bigliardi, P.L.1
  • 77
    • 68349141699 scopus 로고    scopus 로고
    • Influences of opioids and nanoparticles on in vitro wound healing models
    • N.B. Wolf Influences of opioids and nanoparticles on in vitro wound healing models Eur. J. Pharm. Biopharm. 73 2009 34 42
    • (2009) Eur. J. Pharm. Biopharm. , vol.73 , pp. 34-42
    • Wolf, N.B.1
  • 78
    • 77953914789 scopus 로고    scopus 로고
    • 3D-wound healing model: Influence of morphine and solid lipid nanoparticles
    • S. Küchler 3D-wound healing model: influence of morphine and solid lipid nanoparticles J. Biotechnol. 148 2010 24 30
    • (2010) J. Biotechnol. , vol.148 , pp. 24-30
    • Küchler, S.1
  • 79
    • 33646084156 scopus 로고    scopus 로고
    • Deletion of delta-opioid receptor in mice alters skin differentiation and delays wound healing
    • M. Bigliardi-Qi Deletion of delta-opioid receptor in mice alters skin differentiation and delays wound healing Differentiation 74 2006 174 185
    • (2006) Differentiation , vol.74 , pp. 174-185
    • Bigliardi-Qi, M.1
  • 80
    • 49949094428 scopus 로고    scopus 로고
    • Prolonged use of high-dose morphine impairs angiogenesis and mobilization of endothelial progenitor cells in mice
    • C.F. Lam Prolonged use of high-dose morphine impairs angiogenesis and mobilization of endothelial progenitor cells in mice Anesth. Analg. 107 2008 686 692
    • (2008) Anesth. Analg. , vol.107 , pp. 686-692
    • Lam, C.F.1
  • 81
    • 67349206203 scopus 로고    scopus 로고
    • Effectiveness of topical administration of opioids in palliative care: A systematic review
    • B. LeBon Effectiveness of topical administration of opioids in palliative care: a systematic review J. Pain Symptom Manage. 37 2009 913 917
    • (2009) J. Pain Symptom Manage. , vol.37 , pp. 913-917
    • Lebon, B.1
  • 82
    • 40549102816 scopus 로고    scopus 로고
    • Topical ketamine and morphine for post-tonsillectomy pain
    • O. Canbay Topical ketamine and morphine for post-tonsillectomy pain Eur. J. Anaesthesiol. 25 2008 287 292
    • (2008) Eur. J. Anaesthesiol. , vol.25 , pp. 287-292
    • Canbay, O.1
  • 83
    • 84873701844 scopus 로고    scopus 로고
    • A thermosensitive morphine-containing hydrogel for the treatment of large-scale skin wounds
    • S. Heilmann A thermosensitive morphine-containing hydrogel for the treatment of large-scale skin wounds Int. J. Pharm. 444 2013 96 102
    • (2013) Int. J. Pharm. , vol.444 , pp. 96-102
    • Heilmann, S.1
  • 84
    • 84871797365 scopus 로고    scopus 로고
    • Moving from static to dynamic complexity in hydrogel design
    • J.A. Burdick, and W.L. Murphy Moving from static to dynamic complexity in hydrogel design Nat. Commun. 3 2012 1269
    • (2012) Nat. Commun. , vol.3 , pp. 1269
    • Burdick, J.A.1    Murphy, W.L.2
  • 85
    • 0038037320 scopus 로고    scopus 로고
    • Opioid growth factor modulation of corneal epithelium: Uppers and downers
    • J.W. Sassani Opioid growth factor modulation of corneal epithelium: uppers and downers Curr. Eye Res. 26 2003 249 262
    • (2003) Curr. Eye Res. , vol.26 , pp. 249-262
    • Sassani, J.W.1
  • 86
    • 48949118958 scopus 로고    scopus 로고
    • Temporal effects of topical morphine application on cutaneous wound healing
    • J.M. Rook Temporal effects of topical morphine application on cutaneous wound healing Anesthesiology 109 2008 130 136
    • (2008) Anesthesiology , vol.109 , pp. 130-136
    • Rook, J.M.1
  • 87
    • 70449707540 scopus 로고    scopus 로고
    • Role of macrophages in normal wound healing: An overview
    • R. Adamson Role of macrophages in normal wound healing: an overview J. Wound Care 18 2009 349 351
    • (2009) J. Wound Care , vol.18 , pp. 349-351
    • Adamson, R.1
  • 88
    • 77949905452 scopus 로고    scopus 로고
    • Molecular dissection of abnormal wound healing processes resulting in keloid disease
    • B. Shih Molecular dissection of abnormal wound healing processes resulting in keloid disease Wound Repair Regen. 18 2010 139 153
    • (2010) Wound Repair Regen. , vol.18 , pp. 139-153
    • Shih, B.1
  • 89
    • 16444369890 scopus 로고    scopus 로고
    • Exogenous administration of Substance P enhances wound healing in a novel skin-injury model
    • A.V. Delgado Exogenous administration of Substance P enhances wound healing in a novel skin-injury model Exp. Biol. Med. (Maywood) 230 2005 271 280
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , pp. 271-280
    • Delgado, A.V.1
  • 90
    • 77956664657 scopus 로고    scopus 로고
    • Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing
    • L. da Silva Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing Expert Opin. Biol. Ther. 10 2010 1427 1439
    • (2010) Expert Opin. Biol. Ther. , vol.10 , pp. 1427-1439
    • Da Silva, L.1
  • 91
    • 0029811783 scopus 로고    scopus 로고
    • Sensory peptides as neuromodulators of wound healing in aged rats
    • Z. Khalil, and R. Helme Sensory peptides as neuromodulators of wound healing in aged rats J. Gerontol. A. Biol. Sci. Med. Sci. 51 1996 B354 B361
    • (1996) J. Gerontol. A. Biol. Sci. Med. Sci. , vol.51
    • Khalil, Z.1    Helme, R.2
  • 92
    • 64249140130 scopus 로고    scopus 로고
    • Morphine-induced early delays in wound closure: Involvement of sensory neuropeptides and modification of neurokinin receptor expression
    • J.M. Rook Morphine-induced early delays in wound closure: Involvement of sensory neuropeptides and modification of neurokinin receptor expression Biochem. Pharmacol. 77 2009 1747 1755
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 1747-1755
    • Rook, J.M.1
  • 93
    • 34447629192 scopus 로고    scopus 로고
    • Delay of cutaneous wound closure by morphine via local blockade of peripheral tachykinin release
    • J.M. Rook, and K.E. McCarson Delay of cutaneous wound closure by morphine via local blockade of peripheral tachykinin release Biochem. Pharmacol. 74 2007 752 757
    • (2007) Biochem. Pharmacol. , vol.74 , pp. 752-757
    • Rook, J.M.1    McCarson, K.E.2
  • 94
    • 0342437530 scopus 로고    scopus 로고
    • Intraarticular morphine analgesia in chronic pain patients with osteoarthritis
    • R. Likar Intraarticular morphine analgesia in chronic pain patients with osteoarthritis Anesth. Analg. 84 1997 1313 1317
    • (1997) Anesth. Analg. , vol.84 , pp. 1313-1317
    • Likar, R.1
  • 95
    • 0032752320 scopus 로고    scopus 로고
    • Intraarticular morphine versus dexamethasone in chronic arthritis
    • A. Stein Intraarticular morphine versus dexamethasone in chronic arthritis Pain 83 1999 525 532
    • (1999) Pain , vol.83 , pp. 525-532
    • Stein, A.1
  • 96
    • 0033738840 scopus 로고    scopus 로고
    • Neurotransmitter modulation of interleukin 6 (IL-6) and IL-8 secretion of synovial fibroblasts in patients with rheumatoid arthritis compared to osteoarthritis
    • T. Raap Neurotransmitter modulation of interleukin 6 (IL-6) and IL-8 secretion of synovial fibroblasts in patients with rheumatoid arthritis compared to osteoarthritis J. Rheumatol. 27 2000 2558 2565
    • (2000) J. Rheumatol. , vol.27 , pp. 2558-2565
    • Raap, T.1
  • 97
    • 0034785197 scopus 로고    scopus 로고
    • Endorphin and enkephalin ameliorate excessive synovial cell functions in patients with rheumatoid arthritis
    • Y. Takeba Endorphin and enkephalin ameliorate excessive synovial cell functions in patients with rheumatoid arthritis J. Rheumatol. 28 2001 2176 2183
    • (2001) J. Rheumatol. , vol.28 , pp. 2176-2183
    • Takeba, Y.1
  • 98
    • 39749155759 scopus 로고    scopus 로고
    • Antiinflammatory role of endomorphins in osteoarthritis, rheumatoid arthritis, and adjuvant-induced polyarthritis
    • R.H. Straub Antiinflammatory role of endomorphins in osteoarthritis, rheumatoid arthritis, and adjuvant-induced polyarthritis Arthritis Rheum. 58 2008 456 466
    • (2008) Arthritis Rheum. , vol.58 , pp. 456-466
    • Straub, R.H.1
  • 99
    • 74549185157 scopus 로고    scopus 로고
    • Ketorolac but not morphine exerts inflammatory and metabolic effects in synovial membrane after knee arthroscopy: A double-blind randomized prospective study using the microdialysis technique
    • A. Stalman Ketorolac but not morphine exerts inflammatory and metabolic effects in synovial membrane after knee arthroscopy: a double-blind randomized prospective study using the microdialysis technique Reg. Anesth. Pain Med. 34 2009 557 564
    • (2009) Reg. Anesth. Pain Med. , vol.34 , pp. 557-564
    • Stalman, A.1
  • 100
    • 2542492932 scopus 로고    scopus 로고
    • Practice guidelines for acute pain management in the perioperative setting: An updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management
    • American Society of Anesthesiologists Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management Anesthesiology 100 2004 1573 1581
    • (2004) Anesthesiology , vol.100 , pp. 1573-1581
    • Society Of Anesthesiologists, A.1
  • 101
    • 33745251654 scopus 로고    scopus 로고
    • Pain management in horses and farm animals
    • A. Valverde, and C.I. Gunkel Pain management in horses and farm animals J. Vet. Emerg. Crit. Care 15 2005 295 307
    • (2005) J. Vet. Emerg. Crit. Care , vol.15 , pp. 295-307
    • Valverde, A.1    Gunkel, C.I.2
  • 102
    • 76149131711 scopus 로고    scopus 로고
    • Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site
    • J.L. Martin Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site Am. J. Pathol. 176 2010 786 799
    • (2010) Am. J. Pathol. , vol.176 , pp. 786-799
    • Martin, J.L.1
  • 103
    • 0035692685 scopus 로고    scopus 로고
    • Morphine sulfate inhibits hypoxia-induced vascular endothelial growth factor expression in endothelial cells and cardiac myocytes
    • S. Balasubramanian Morphine sulfate inhibits hypoxia-induced vascular endothelial growth factor expression in endothelial cells and cardiac myocytes J. Mol. Cell. Cardiol. 33 2001 2179 2187
    • (2001) J. Mol. Cell. Cardiol. , vol.33 , pp. 2179-2187
    • Balasubramanian, S.1
  • 104
    • 37849050550 scopus 로고    scopus 로고
    • Loperamide: A pharmacological review
    • D.E. Baker Loperamide: a pharmacological review Rev. Gastroenterol. Disord. 7 Suppl. 3 2007 11 18
    • (2007) Rev. Gastroenterol. Disord. , vol.7 , Issue.SUPPL. 3 , pp. 11-18
    • Baker, D.E.1
  • 105
    • 0022375397 scopus 로고
    • Effects of peptide hormones in urate crystal inflammation
    • C.W. Denko, and P. Gabriel Effects of peptide hormones in urate crystal inflammation J. Rheumatol. 12 1985 971 975
    • (1985) J. Rheumatol. , vol.12 , pp. 971-975
    • Denko, C.W.1    Gabriel, P.2
  • 106
    • 16844379124 scopus 로고    scopus 로고
    • Opioids heal ischemic wounds in the rat
    • T. Poonawala Opioids heal ischemic wounds in the rat Wound Repair Regen. 13 2005 165 174
    • (2005) Wound Repair Regen. , vol.13 , pp. 165-174
    • Poonawala, T.1
  • 107
    • 0033008936 scopus 로고    scopus 로고
    • Involvement of substance P in the anti-inflammatory effects of the peripherally selective kappa-opioid asimadoline and the NK1 antagonist GR205171
    • W. Binder Involvement of substance P in the anti-inflammatory effects of the peripherally selective kappa-opioid asimadoline and the NK1 antagonist GR205171 Eur. J. Neurosci. 11 1999 2065 2072
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2065-2072
    • Binder, W.1


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