Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons

Journal of Neuroscience

Volumn 21, Issue 20, 2001, Pages 7881-7888

  Braz, Joao ^a   Beaufour, Caroline ^a   Coutaux, Anne ^a   Epstein, Alberto L ^b   Cesselin, François ^a   Hamon, Michel ^a   Pohl, Michel ^a,c  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

^c INSERM   (France)

Author keywords

Dorsal root sensory ganglia neurons; Improved polyarthritis related disability; Limited joint destruction; Polyarthritic rats; Proenkephalin A overproduction; Reduced hyperalgesia

Indexed keywords

ENKEPHALIN; PROENKEPHALIN; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DESTRUCTION; CONTROLLED STUDY; DRUG EFFICACY; GENE OVEREXPRESSION; GENE THERAPY; HERPES SIMPLEX VIRUS; HYPERALGESIA; LOCOMOTION; NERVE CELL PLASTICITY; NONHUMAN; POLYARTHRITIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SENSORY NERVE;

EID: 0035887602     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-20-07881.2001     Document Type: Article

References (47)

1. Herpes simplex virus1-mediated transfer of preproenkephalin A in rat dorsal root ganglia
2. Met-enkephalin is preferentially transported to the peripheral processes of primary afferent fibres in both normal and proenkephalin A overexpressing rats
3. Effect of the peripherally selective kappaopioid agonist, asimadoline, on adjuvant arthritis
4. Substance P- and CGRP-immunoreactive nerves in bone
5. Pain-related disability and effects of chronic morphine in the adjuvant-induced arthritis model of chronic pain
6. Parallel clinical and behavioural studies of adjuvant-induced arthritis in the rat: Possible relationship with "chronic pain"
7. Immunohistochemical localization of enkephalin in peripheral sensory axons in the rat
8. 125I-beta-endorphin binding sites in the articular cartilage of the rat
9. Metenkephalin levels and opiate receptors in the spinal cord of chronic suffering rats
10. Spinal mechanisms of opioid analgesia
11. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
12. Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate
13. Evidence that adjuvant arthritis in the rat is associated with chronic pain
14. Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors
15. Adjuvant-induced arthritis in rats: A possible animal model of chronic pain
16. Methionine-enkephalin in bone and joint tissues
17. A paracrine paradigm for in vivo gene therapy in the central nervous system: Treatment of chronic pain
18. A system to measure thermal nociception
19. A defective HSV-1 vector expresses Escherichia coli β-galactosidase in cultured peripheral neurons
20. Herpes simplex virus type 1 vector-mediated expression of nerve growth factor protects dorsal root ganglion neurons from peroxide toxicity
21. Use of Freund's adjuvant arthritis test in anti-inflammatory drug screening in the rat: Value of animal selection and preparation at the breeding center
22. Rheumatoid arthritis. Pathophysiology and implications for therapy
23. Distribution of CGRP-, VIP-, D beta H-, SP-, and NPY-immunoreactive nerves in the periosteum of the rat
24. Peripheral morphine administration blocks the development of hyperalgesia and allodynia after bone damage in the rat
25. Distribution of nerve endings and sensory neuropeptides in rat synovium, meniscus and bone
26. Gene therapy for arthritis 1996-1999
27. Increased calcitonin gene-related peptide (CGRP), substance P, and enkephalin immunoreactivities in dorsal spinal cord and loss of CGRP-immunoreactive motoneurons in arthritic rats depend on intact peripheral nerve supply
28. Reduction in locomotor activity of arthritic rats as parameter for chronic pain: Effect of morphine, acetylsalicylic acid and citalopram
29. Contribution of sensory afferent and sympathetic efferents to joint injury in experimental arthritis
30. Chronic morphine reduces pain-related disability in a rodent model of chronic, inflammatory pain
31. Long-term promoter activity during herpes simplex virus latency
32. Opposite effects of μ and δ opioid receptor agonists on the in vitro release of substance P-like material from the rat spinal cord
33. Development of arthritis, periarthritis and periostitis in rats given adjuvant
34. Opioid control of the in vitro release of calcitonin gene-related peptide from primary afferent fibres projecting in the rat cervical cord
35. 5-enkephalin-, and dynorphin A(1-8)-like materials in the spinal cord and dorsal root ganglia of adult rats: Effects of dorsal rhizotomy and neonatal capsaicin
36. Expression of preproenkephalin A gene and presence of met-enkephalin in dorsal root ganglia of the adult rat
37. Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat: In vivo release and cDNA hybridization studies
38. Interleukin 1β and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue
39. Increase in substance P and CGRP, but not somatostatin content of innervating dorsal root ganglia in adjuvant monoarthritis in the rat
40. Long-term expression in sensory neurons in tissue culture from herpes simplex virus type 1 (HSV-1) promoters in an HSV-1-derived vector
41. Opioid and opiate immunoregulatory processes
42. Peripheral morphine analgesia
43. Herpes simplex virus latent infection in the nervous system
44. Physical characterization of the herpes simplex virus latency-associated transcript in neurons
45. Effect of mu-opioids morphine and buprenorphine on the development of adjuvant arthritis in rats
46. Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus
47. Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system