Chronic arthritis down-regulates peripheral μ-opioid receptor expression with concomitant loss of endomorphin 1 antinociception

Arthritis and Rheumatism

Volumn 52, Issue 10, 2005, Pages 3210-3219

  Li, Zongming ^a   Proud, David ^a   Zhang, Chunfen ^a   Wiehler, Shahina ^a   McDougall, Jason J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENDOMORPHIN 1; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GALLAMINE TRIETHIODIDE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; MU OPIATE RECEPTOR ANTAGONIST;

ACUTE ARTHRITIS; ACUTE DISEASE; ANALGESIA; ANIMAL CELL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CHRONIC ARTHRITIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE MODEL; DOSE TIME EFFECT RELATION; DRUG EFFICACY; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INHIBITION KINETICS; KNEE PAIN; MALE; MECHANICAL STIMULATION; MUSCLE SPINDLE AFFERENT NERVE; NERVE CELL; NOCICEPTIVE STIMULATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; SENSORY NERVE CELL; SPINAL GANGLION; STATISTICAL SIGNIFICANCE;

ANALGESICS, OPIOID; ANIMALS; ARTHRITIS, EXPERIMENTAL; CHRONIC DISEASE; DOWN-REGULATION; EDEMA; GANGLIA, SPINAL; JOINTS; NEURONS, AFFERENT; NOCICEPTORS; OLIGOPEPTIDES; PAIN; RATS; RATS, WISTAR; RECEPTORS, OPIOID, MU; RNA, MESSENGER;

EID: 26844499513     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21359     Document Type: Article

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