Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model

Journal of Clinical Investigation

Volumn 123, Issue 6, 2013, Pages 2719-2729

  Heng, Mary Y ^a   Lin, Shu Ting ^a   Verret, Laure ^a,b   Huang, Yong ^a   Kamiya, Sherry ^a,c   Padiath, Quasar S ^a,d   Tong, Ying ^a,e   Palop, Jorge J ^a,b   Huang, Eric J ^a,c   Ptáček, Louis J ^a   Fu, Ying Hui ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN B; LAMIN B1; MYELIN; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATIVE MEMORY; ASTROCYTE; AUTOSOMAL DOMINANT LEUKODYSTROPHY; COGNITIVE DEFECT; CONTROLLED STUDY; DEMYELINATION; EPILEPSY; FEMALE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; LEUKODYSTROPHY; MEMORY DISORDER; MOTOR DYSFUNCTION; MOUSE; MYELIN SHEATH; MYELINATION; NERVE FIBER DEGENERATION; NEUROPATHOLOGY; NONHUMAN; OLIGODENDROGLIA; PELIZAEUS MERZBACHER DISEASE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEOMICS; SEIZURE; SPATIAL MEMORY; STATE DEPENDENT LEARNING;

ANIMALS; AXONS; DISEASE MODELS, ANIMAL; GAIT ATAXIA; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LAMIN TYPE B; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MYELIN PROTEOLIPID PROTEIN; MYELIN SHEATH; OLIGODENDROGLIA; PELIZAEUS-MERZBACHER DISEASE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; ROTAROD PERFORMANCE TEST; SEIZURES; YY1 TRANSCRIPTION FACTOR;

EID: 84878576304     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66737     Document Type: Article

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