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Volumn 21, Issue 4, 2013, Pages 767-774

SR-A and SREC-I are Kupffer and Endothelial cell receptors for helper-dependent adenoviral vectors

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CELL RECEPTOR; SCAVENGER RECEPTOR; SCAVENGER RECEPTOR A; SCAVENGER RECEPTOR EXPRESSED ON ENDOTHELIAL CELLS 1; UNCLASSIFIED DRUG;

EID: 84878568088     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.287     Document Type: Article
Times cited : (50)

References (50)
  • 1
    • 79956014843 scopus 로고    scopus 로고
    • Helper-dependent adenoviral vectors for liver-directed gene therapy
    • Brunetti-Pierri, N and Ng, P (2011). Helper-dependent adenoviral vectors for liver-directed gene therapy. Hum Mol Genet 20(R1): R7-13.
    • (2011) Hum Mol Genet , vol.20 , Issue.R1
    • Brunetti-Pierri, N.1    Ng, P.2
  • 3
    • 0033756313 scopus 로고    scopus 로고
    • Blood clearance rates of adenovirus type 5 in mice
    • Alemany, R, Suzuki, K and Curiel, DT (2000). Blood clearance rates of adenovirus type 5 in mice. J Gen Virol 81(Pt 11): 2605-2609.
    • (2000) J Gen Virol , vol.81 , Issue.PART 11 , pp. 2605-2609
    • Alemany, R.1    Suzuki, K.2    Curiel, D.T.3
  • 4
    • 0034980914 scopus 로고    scopus 로고
    • Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver
    • Tao, N, Gao, G P, Parr, M, Johnston, J, Baradet, T, Wilson, JM et al. (2001). Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. Mol Ther 3: 28-35.
    • (2001) Mol Ther , vol.3 , pp. 28-35
    • Tao, N.1    Gao, G.P.2    Parr, M.3    Johnston, J.4    Baradet, T.5    Wilson, J.M.6
  • 5
    • 0034986416 scopus 로고    scopus 로고
    • Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages
    • Zhang, Y, Chirmule, N, Gao, GP, Qian, R, Croyle, M, Joshi, B et al. (2001). Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. Mol Ther 3(5 Pt 1): 697-707.
    • (2001) Mol Ther , vol.3 , Issue.5 PART 1 , pp. 697-707
    • Zhang, Y.1    Chirmule, N.2    Gao, G.P.3    Qian, R.4    Croyle, M.5    Joshi, B.6
  • 6
    • 1542359538 scopus 로고    scopus 로고
    • Unexpected pulmonary uptake of adenovirus vectors in animals with chronic liver disease
    • Smith, JS, Tian, J, Muller, J and Byrnes, AP (2004). Unexpected pulmonary uptake of adenovirus vectors in animals with chronic liver disease. Gene Ther 11: 431-438.
    • (2004) Gene Ther , vol.11 , pp. 431-438
    • Smith, J.S.1    Tian, J.2    Muller, J.3    Byrnes, A.P.4
  • 7
    • 0030756389 scopus 로고    scopus 로고
    • The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors
    • Lieber, A, He, CY, Meuse, L, Schowalter, D, Kirillova, I, Winther, B et al. (1997). The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors. J Virol 71: 8798-8807.
    • (1997) J Virol , vol.71 , pp. 8798-8807
    • Lieber, A.1    He, C.Y.2    Meuse, L.3    Schowalter, D.4    Kirillova, I.5    Winther, B.6
  • 8
    • 0742307422 scopus 로고    scopus 로고
    • Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates
    • Brunetti-Pierri, N, Palmer, DJ, Beaudet, AL, Carey, KD, Finegold, M and Ng, P (2004). Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates. Hum Gene Ther 15: 35-46.
    • (2004) Hum Gene Ther , vol.15 , pp. 35-46
    • Brunetti-Pierri, N.1    Palmer, D.J.2    Beaudet, A.L.3    Carey, K.D.4    Finegold, M.5    Ng, P.6
  • 9
    • 0036145244 scopus 로고    scopus 로고
    • Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons
    • Morral, N, O'Neal, WK, Rice, K, Leland, MM, Piedra, PA, Aguilar-Córdova, E et al. (2002). Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons. Hum Gene Ther 13: 143-154.
    • (2002) Hum Gene Ther , vol.13 , pp. 143-154
    • Morral, N.1    O'Neal, W.K.2    Rice, K.3    Leland, M.M.4    Piedra, P.A.5    Aguilar-Córdova, E.6
  • 10
    • 7044235842 scopus 로고    scopus 로고
    • AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: A randomised, controlled study
    • Immonen, A, Vapalahti, M, Tyynelä, K, Hurskainen, H, Sandmair, A, Vanninen, R et al. (2004). AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol Ther 10: 967-972.
    • (2004) Mol Ther , vol.10 , pp. 967-972
    • Immonen, A.1    Vapalahti, M.2    Tyynelä, K.3    Hurskainen, H.4    Sandmair, A.5    Vanninen, R.6
  • 11
    • 0035134629 scopus 로고    scopus 로고
    • Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?
    • Kirn, D (2001). Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned? Gene Ther 8: 89-98.
    • (2001) Gene Ther , vol.8 , pp. 89-98
    • Kirn, D.1
  • 12
    • 24944454988 scopus 로고    scopus 로고
    • Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
    • Peng, Z (2005). Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum Gene Ther 16: 1016-1027.
    • (2005) Hum Gene Ther , vol.16 , pp. 1016-1027
    • Peng, Z.1
  • 13
    • 0034990761 scopus 로고    scopus 로고
    • Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: Safety, feasibility and biological activity
    • Nemunaitis, J, Cunningham, C, Buchanan, A, Blackburn, A, Edelman, G, Maples, P et al. (2001). Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity. Gene Ther 8: 746-759.
    • (2001) Gene Ther , vol.8 , pp. 746-759
    • Nemunaitis, J.1    Cunningham, C.2    Buchanan, A.3    Blackburn, A.4    Edelman, G.5    Maples, P.6
  • 14
    • 35048816872 scopus 로고    scopus 로고
    • A phase i trial of intravenous infusion of ONYX-015 and enbrel in solid tumor patients
    • Nemunaitis, J, Senzer, N, Sarmiento, S, Zhang, YA, Arzaga, R, Sands, B et al. (2007). A phase I trial of intravenous infusion of ONYX-015 and enbrel in solid tumor patients. Cancer Gene Ther 14: 885-893.
    • (2007) Cancer Gene Ther , vol.14 , pp. 885-893
    • Nemunaitis, J.1    Senzer, N.2    Sarmiento, S.3    Zhang, Y.A.4    Arzaga, R.5    Sands, B.6
  • 15
    • 72949092147 scopus 로고    scopus 로고
    • Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells
    • Koski, A, Rajecki, M, Guse, K, Kanerva, A, Ristimäki, A, Pesonen, S et al. (2009). Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells. J Gene Med 11: 966-977.
    • (2009) J Gene Med , vol.11 , pp. 966-977
    • Koski, A.1    Rajecki, M.2    Guse, K.3    Kanerva, A.4    Ristimäki, A.5    Pesonen, S.6
  • 16
    • 77955172821 scopus 로고    scopus 로고
    • Recognition of virus infection and innate host responses to viral gene therapy vectors
    • Shayakhmetov, DM, Di Paolo, NC and Mossman, KL (2010). Recognition of virus infection and innate host responses to viral gene therapy vectors. Mol Ther 18: 1422-1429.
    • (2010) Mol Ther , vol.18 , pp. 1422-1429
    • Shayakhmetov, D.M.1    Di Paolo, N.C.2    Mossman, K.L.3
  • 17
    • 63949088129 scopus 로고    scopus 로고
    • Redundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver
    • Di Paolo, NC, van Rooijen, N and Shayakhmetov, DM (2009). Redundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver. Mol Ther 17: 675-684.
    • (2009) Mol Ther , vol.17 , pp. 675-684
    • Di Paolo, N.C.1    Van Rooijen, N.2    Shayakhmetov, D.M.3
  • 18
    • 44649137607 scopus 로고    scopus 로고
    • Polyinosinic acid enhances delivery of adenovirus vectors in vivo by preventing sequestration in liver macrophages
    • Haisma, HJ, Kamps, JA, Kamps, GK, Plantinga, JA, Rots, MG and Bellu, AR (2008). Polyinosinic acid enhances delivery of adenovirus vectors in vivo by preventing sequestration in liver macrophages. J Gen Virol 89(Pt 5): 1097-1105.
    • (2008) J Gen Virol , vol.89 , Issue.PART 5 , pp. 1097-1105
    • Haisma, H.J.1    Kamps, J.A.2    Kamps, G.K.3    Plantinga, J.A.4    Rots, M.G.5    Bellu, A.R.6
  • 20
    • 79960016902 scopus 로고    scopus 로고
    • Advances and future challenges in adenoviral vector pharmacology and targeting
    • Khare, R, Chen, CY, Weaver, EA and Barry, MA (2011). Advances and future challenges in adenoviral vector pharmacology and targeting. Curr Gene Ther 11: 241-258.
    • (2011) Curr Gene Ther , vol.11 , pp. 241-258
    • Khare, R.1    Chen, C.Y.2    Weaver, E.A.3    Barry, M.A.4
  • 21
    • 18944396179 scopus 로고    scopus 로고
    • Adenovirus binding to blood factors results in liver cell infection and hepatotoxicity
    • Shayakhmetov, DM, Gaggar, A, Ni, S, Li, ZY and Lieber, A (2005). Adenovirus binding to blood factors results in liver cell infection and hepatotoxicity. J Virol 79: 7478-7491.
    • (2005) J Virol , vol.79 , pp. 7478-7491
    • Shayakhmetov, D.M.1    Gaggar, A.2    Ni, S.3    Li, Z.Y.4    Lieber, A.5
  • 23
    • 44349168239 scopus 로고    scopus 로고
    • Interaction of systemically delivered adenovirus vectors with Kupffer cells in mouse liver
    • Smith, JS, Xu, Z, Tian, J, Stevenson, SC and Byrnes, AP (2008). Interaction of systemically delivered adenovirus vectors with Kupffer cells in mouse liver. Hum Gene Ther 19: 547-554.
    • (2008) Hum Gene Ther , vol.19 , pp. 547-554
    • Smith, J.S.1    Xu, Z.2    Tian, J.3    Stevenson, S.C.4    Byrnes, A.P.5
  • 24
    • 0029858179 scopus 로고    scopus 로고
    • Comparison of adenovirus gene transfer to vascular endothelial cells in cell culture, organ culture, and in vivo
    • Merrick, AF, Shewring, LD, Sawyer, GJ, Gustafsson, KT and Fabre, JW (1996). Comparison of adenovirus gene transfer to vascular endothelial cells in cell culture, organ culture, and in vivo. Transplantation 62: 1085-1089.
    • (1996) Transplantation , vol.62 , pp. 1085-1089
    • Merrick, A.F.1    Shewring, L.D.2    Sawyer, G.J.3    Gustafsson, K.T.4    Fabre, J.W.5
  • 26
    • 56449103203 scopus 로고    scopus 로고
    • Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement
    • Xu, Z, Tian, J, Smith, JS and Byrnes, AP (2008). Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement. J Virol 82: 11705-11713.
    • (2008) J Virol , vol.82 , pp. 11705-11713
    • Xu, Z.1    Tian, J.2    Smith, J.S.3    Byrnes, A.P.4
  • 27
    • 84857079734 scopus 로고    scopus 로고
    • Identifcation of adenovirus serotype 5 hexon regions that interact with scavenger receptors
    • Khare, R, Reddy, VS, Nemerow, GR and Barry, MA (2012). Identifcation of adenovirus serotype 5 hexon regions that interact with scavenger receptors. J Virol 86: 2293-2301.
    • (2012) J Virol , vol.86 , pp. 2293-2301
    • Khare, R.1    Reddy, V.S.2    Nemerow, G.R.3    Barry, M.A.4
  • 28
    • 37049038626 scopus 로고    scopus 로고
    • A quantitative assay for measuring clearance of adenovirus vectors by Kupffer cells
    • Smith, JS, Xu, Z and Byrnes, AP (2008). A quantitative assay for measuring clearance of adenovirus vectors by Kupffer cells. J Virol Methods 147: 54-60.
    • (2008) J Virol Methods , vol.147 , pp. 54-60
    • Smith, J.S.1    Xu, Z.2    Byrnes, A.P.3
  • 29
    • 33645912596 scopus 로고    scopus 로고
    • Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates
    • Brunetti-Pierri, N, Ng, T, Iannitti, DA, Palmer, DJ, Beaudet, AL, Finegold, MJ et al. (2006). Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates. Hum Gene Ther 17: 391-404.
    • (2006) Hum Gene Ther , vol.17 , pp. 391-404
    • Brunetti-Pierri, N.1    Ng, T.2    Iannitti, D.A.3    Palmer, D.J.4    Beaudet, A.L.5    Finegold, M.J.6
  • 30
    • 33947244363 scopus 로고    scopus 로고
    • Pseudo-hydrodynamic delivery of helper-dependent adenoviral vectors into non-human primates for liver-directed gene therapy
    • Brunetti-Pierri, N, Stapleton, GE, Palmer, DJ, Zuo, Y, Mane, VP, Finegold, MJ et al. (2007). Pseudo-hydrodynamic delivery of helper-dependent adenoviral vectors into non-human primates for liver-directed gene therapy. Mol Ther 15: 732-740.
    • (2007) Mol Ther , vol.15 , pp. 732-740
    • Brunetti-Pierri, N.1    Stapleton, G.E.2    Palmer, D.J.3    Zuo, Y.4    Mane, V.P.5    Finegold, M.J.6
  • 31
    • 28844464465 scopus 로고    scopus 로고
    • Rapid Kupffer cell death after intravenous injection of adenovirus vectors
    • Manickan, E, Smith, JS, Tian, J, Eggerman, TL, Lozier, JN, Muller, J et al. (2006). Rapid Kupffer cell death after intravenous injection of adenovirus vectors. Mol Ther 13: 108-117.
    • (2006) Mol Ther , vol.13 , pp. 108-117
    • Manickan, E.1    Smith, J.S.2    Tian, J.3    Eggerman, T.L.4    Lozier, J.N.5    Muller, J.6
  • 32
    • 0032977440 scopus 로고    scopus 로고
    • Scavenger receptor defciency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
    • de Winther, MP, Gijbels, MJ, van Dijk, KW, van Gorp, PJ, suzuki, H, Kodama, T et al. (1999). Scavenger receptor defciency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice. Atherosclerosis 144: 315-321.
    • (1999) Atherosclerosis , vol.144 , pp. 315-321
    • De Winther, M.P.1    Gijbels, M.J.2    Van Dijk, K.W.3    Van Gorp, P.J.4    Suzuki, H.5    Kodama, T.6
  • 33
    • 77951641349 scopus 로고    scopus 로고
    • The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells
    • Beauvillain, C, Meloni, F, Sirard, JC, Blanchard, S, Jarry, U, Scotet, M et al. (2010). The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells. J Hepatol 52: 644-651.
    • (2010) J Hepatol , vol.52 , pp. 644-651
    • Beauvillain, C.1    Meloni, F.2    Sirard, J.C.3    Blanchard, S.4    Jarry, U.5    Scotet, M.6
  • 34
    • 79751525404 scopus 로고    scopus 로고
    • The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells i (SREC-I)
    • Hölzl, MA, Hofer, J, Kovarik, JJ, Roggenbuck, D, Reinhold, D, Goihl, A et al. (2011). The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I). Cell Immunol 267: 88-93.
    • (2011) Cell Immunol , vol.267 , pp. 88-93
    • Hölzl, M.A.1    Hofer, J.2    Kovarik, J.J.3    Roggenbuck, D.4    Reinhold, D.5    Goihl, A.6
  • 35
    • 3843116691 scopus 로고    scopus 로고
    • Scavenger receptor expressed by endothelial cells i (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide
    • Tamura, Y, Osuga, J, Adachi, H, Tozawa, R, Takanezawa, Y, Ohashi, K et al. (2004). Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide. J Biol Chem 279: 30938-30944.
    • (2004) J Biol Chem , vol.279 , pp. 30938-30944
    • Tamura, Y.1    Osuga, J.2    Adachi, H.3    Tozawa, R.4    Takanezawa, Y.5    Ohashi, K.6
  • 36
    • 74949114755 scopus 로고    scopus 로고
    • Large-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories
    • Suzuki, M, Cela, R, Clarke, C, Bertin, TK, Mouriño, S and Lee, B (2010). Large-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories. Hum Gene Ther 21: 120-126.
    • (2010) Hum Gene Ther , vol.21 , pp. 120-126
    • Suzuki, M.1    Cela, R.2    Clarke, C.3    Bertin, T.K.4    Mouriño, S.5    Lee, B.6
  • 37
    • 0033778881 scopus 로고    scopus 로고
    • Polymorphism of class A scavenger receptors in C57BL/6 mice
    • Daugherty, A, Whitman, SC, Block, AE and Rateri, DL (2000). Polymorphism of class A scavenger receptors in C57BL/6 mice. J Lipid Res 41: 1568-1577.
    • (2000) J Lipid Res , vol.41 , pp. 1568-1577
    • Daugherty, A.1    Whitman, S.C.2    Block, A.E.3    Rateri, D.L.4
  • 38
    • 28844493201 scopus 로고    scopus 로고
    • Lipid emulsions potently increase transgene expression in hepatocytes after adenoviral transfer
    • Snoeys, J, Mertens, G, Lievens, J, van Berkel, T, Collen, D, Biessen, EA et al. (2006). Lipid emulsions potently increase transgene expression in hepatocytes after adenoviral transfer. Mol Ther 13: 98-107.
    • (2006) Mol Ther , vol.13 , pp. 98-107
    • Snoeys, J.1    Mertens, G.2    Lievens, J.3    Van Berkel, T.4    Collen, D.5    Biessen, E.A.6
  • 39
    • 0029049810 scopus 로고
    • The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake
    • Kawabata, K, Takakura, Y and Hashida, M (1995). The fate of plasmid DNA after intravenous injection in mice: involvement of scavenger receptors in its hepatic uptake. Pharm Res 12: 825-830.
    • (1995) Pharm Res , vol.12 , pp. 825-830
    • Kawabata, K.1    Takakura, Y.2    Hashida, M.3
  • 40
    • 0034800455 scopus 로고    scopus 로고
    • Is the class A macrophage scavenger receptor (SR-A) multifunctional?-The mouse's tale
    • Platt, N and Gordon, S (2001). Is the class A macrophage scavenger receptor (SR-A) multifunctional?-The mouse's tale. J Clin Invest 108: 649-654.
    • (2001) J Clin Invest , vol.108 , pp. 649-654
    • Platt, N.1    Gordon, S.2
  • 43
    • 67650102353 scopus 로고    scopus 로고
    • Scavenger receptors: Role in innate immunity and microbial pathogenesis
    • Areschoug, T and Gordon, S (2009). Scavenger receptors: role in innate immunity and microbial pathogenesis. Cell Microbiol 11: 1160-1169.
    • (2009) Cell Microbiol , vol.11 , pp. 1160-1169
    • Areschoug, T.1    Gordon, S.2
  • 44
    • 34547882750 scopus 로고    scopus 로고
    • Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I
    • Facciponte, JG, Wang, XY and Subjeck, JR (2007). Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I. Eur J Immunol 37: 2268-2279.
    • (2007) Eur J Immunol , vol.37 , pp. 2268-2279
    • Facciponte, J.G.1    Wang, X.Y.2    Subjeck, J.R.3
  • 45
    • 85027921140 scopus 로고    scopus 로고
    • Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer
    • Khare, R, May, SM, Vetrini, F, Weaver, EA, Palmer, D, Rosewell, A et al. (2011). Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer. Mol Ther 19: 1254-1262.
    • (2011) Mol Ther , vol.19 , pp. 1254-1262
    • Khare, R.1    May, S.M.2    Vetrini, F.3    Weaver, E.A.4    Palmer, D.5    Rosewell, A.6
  • 46
    • 10944247251 scopus 로고    scopus 로고
    • Evaluation of polyethylene glycol modifcation of frst-generation and helper-dependent adenoviral vectors to reduce innate immune responses
    • Mok, H, Palmer, DJ, Ng, P and Barry, MA (2005). Evaluation of polyethylene glycol modifcation of frst-generation and helper-dependent adenoviral vectors to reduce innate immune responses. Mol Ther 11: 66-79.
    • (2005) Mol Ther , vol.11 , pp. 66-79
    • Mok, H.1    Palmer, D.J.2    Ng, P.3    Barry, M.A.4
  • 47
    • 4444374585 scopus 로고    scopus 로고
    • Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus
    • Green, NK, Herbert, CW, Hale, SJ, Hale, AB, Mautner, V, Harkins, R et al. (2004). Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus. Gene Ther 11: 1256-1263.
    • (2004) Gene Ther , vol.11 , pp. 1256-1263
    • Green, N.K.1    Herbert, C.W.2    Hale, S.J.3    Hale, A.B.4    Mautner, V.5    Harkins, R.6
  • 48
    • 0346872991 scopus 로고    scopus 로고
    • Improved system for helper-dependent adenoviral vector production
    • Palmer, D and Ng, P (2003). Improved system for helper-dependent adenoviral vector production. Mol Ther 8: 846-852.
    • (2003) Mol Ther , vol.8 , pp. 846-852
    • Palmer, D.1    Ng, P.2
  • 49
    • 33746658599 scopus 로고    scopus 로고
    • Infection with replication-defcient adenovirus induces changes in the dynamic instability of host cell microtubules
    • Warren, JC, Rutkowski, A and Cassimeris, L (2006). Infection with replication-defcient adenovirus induces changes in the dynamic instability of host cell microtubules. Mol Biol Cell 17: 3557-3568.
    • (2006) Mol Biol Cell , vol.17 , pp. 3557-3568
    • Warren, J.C.1    Rutkowski, A.2    Cassimeris, L.3
  • 50
    • 20844460836 scopus 로고    scopus 로고
    • Increased hepatic transduction with reduced systemic dissemination and proinfammatory cytokines following hydrodynamic injection of helper-dependent adenoviral vectors
    • Brunetti-Pierri, N, Palmer, DJ, Mane, V, Finegold, M, Beaudet, AL and Ng, P (2005). Increased hepatic transduction with reduced systemic dissemination and proinfammatory cytokines following hydrodynamic injection of helper-dependent adenoviral vectors. Mol Ther 12: 99-106.
    • (2005) Mol Ther , vol.12 , pp. 99-106
    • Brunetti-Pierri, N.1    Palmer, D.J.2    Mane, V.3    Finegold, M.4    Beaudet, A.L.5    Ng, P.6


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