The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells

Journal of Hepatology

Volumn 52, Issue 5, 2010, Pages 644-651

  Beauvillain, Céline ^a,b,c   Meloni, Francesca ^d   Sirard, Jean Claude ^e   Blanchard, Simon ^a,b,c   Jarry, Ulrich ^a,b   Scotet, Mari ^a,b   Magistrelli, Giovanni ^f   Delneste, Yves ^a,b,c   Barnaba, Vincenzo ^d   Jeannin, Pascale ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ D'ANGERS   (France)

^c ANGERS UNIVERSITY HOSPITAL   (France)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e INSTITUT PASTEUR DE LILLE   (France)

^f NOVIMMUNE SA   (Switzerland)

Author keywords

Cooperation between innate receptors; Cross presentation; HCV NS3; Scavenger receptors; TLR2; Vaccine vector

Indexed keywords

CYTOKINE; NONSTRUCTURAL PROTEIN 3; PROTEIN SRA 1; PROTEIN SREC 1; SCAVENGER RECEPTOR; SCAVENGER RECEPTOR 1; SCAVENGER RECEPTOR EXPRESSED BY ENDOTHELIUM CELLS; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CLONE; CELL DIFFERENTIATION; CELL STIMULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD14; BONE MARROW CELLS; CELL DIFFERENTIATION; CHO CELLS; CRICETINAE; CRICETULUS; DENDRITIC CELLS; ENDOCYTOSIS; HEPACIVIRUS; HUMANS; MICE; MONOCYTES; MYELOID CELLS; RECEPTORS, SCAVENGER; RECOMBINANT PROTEINS; SCAVENGER RECEPTORS, CLASS F; TOLL-LIKE RECEPTOR 2; TRANSFECTION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 77951641349     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2009.11.031     Document Type: Article

References (38)

1. Palm N.W., and Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol Rev 227 (2009) 221-233
2. Takamizawa A., Mori C., Fuke I., Manabe S., Murakami S., Fujita J., et al. Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol 65 (1991) 1105-1113
3. Hoofnagle J.H. Course and outcome of hepatitis C. Hepatology 36 (2002) S21-S29
4. Manns M.P., Wedemeyer H., and Cornberg M. Treating viral hepatitis C: efficacy, side effects, and complications. Gut 55 (2006) 1350-1359
5. Pileri P., Uematsu Y., Campagnoli S., Galli G., Falugi F., Petracca R., et al. Binding of hepatitis C virus to CD81. Science 282 (1998) 938-941
6. Meertens L., Bertaux C., Cukierman L., Cormier E., Lavillette D., Cosset F.L., et al. The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus. J Virol 82 (2008) 3555-3560
7. Germi R., Crance J.M., Garin D., Guimet J., Lortat-Jacob H., Ruigrok R.W., et al. Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption. J Med Virol 68 (2002) 206-215
8. Saito T., and Gale Jr. M. Regulation of innate immunity against hepatitis C virus infection. Hepatol Res 38 (2008) 115-122
9. Scarselli E., Ansuini H., Cerino R., Roccasecca R.M., Acali S., Filocamo G., et al. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J 21 (2002) 5017-5025
10. Bartosch B., Vitelli A., Granier C., Goujon C., Dubuisson J., Pascale S., et al. Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor. J Biol Chem 278 (2003) 41624-41630
11. Saito T., Owen D.M., Jiang F., Marcotrigiano J., and Gale Jr. M. Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA. Nature 454 (2008) 523-527
12. Foy E., Li K., Sumpter Jr. R., Loo Y.M., Johnson C.L., Wang C., et al. Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci USA 102 (2005) 2986-2991
13. Li K., Foy E., Ferreon J.C., Nakamura M., Ferreon A.C., Ikeda M., et al. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci USA 102 (2005) 2992-2997
14. Lamonaca V., Missale G., Urbani S., Pilli M., Boni C., Mori C., et al. Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: implications for vaccine development. Hepatology 30 (1999) 1088-1098
15. Fytili P., Dalekos G.N., Schlaphoff V., Suneetha P.V., Sarrazin C., Zauner W., et al. Cross-genotype-reactivity of the immunodominant HCV CD8 T-cell epitope NS3-1073. Vaccine 26 (2008) 3818-3826
16. Dolganiuc A., Oak S., Kodys K., Golenbock D.T., Finberg R.W., Kurt-Jones E., et al. Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation. Gastroenterology 127 (2004) 1513-1524
17. Chang S., Dolganiuc A., and Szabo G. Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins. J Leukoc Biol 82 (2007) 479-487
18. Accapezzato D., Visco V., Francavilla V., Molette C., Donato T., Paroli M., et al. Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo. J Exp Med 202 (2005) 817-828
19. Jin B., Wang R.Y., Qiu Q., Sugauchi F., Grandinetti T., Alter H.J., et al. Induction of potent cellular immune response in mice by hepatitis C virus NS3 protein with double-stranded RNA. Immunology 122 (2007) 15-27
20. Castellino F., Boucher P.E., Eichelberg K., Mayhew M., Rothman J.E., Houghton A.N., et al. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways. J Exp Med 191 (2000) 1957-1964
21. Steiner T.S., Nataro J.P., Poteet-Smith C.E., Smith J.A., and Guerrant R.L. Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells. J Clin Invest 105 (2000) 1769-1777
22. Abraham R., Singh N., Mukhopadhyay A., Basu S.K., Bal V., and Rath S. Modulation of immunogenicity and antigenicity of proteins by maleylation to target scavenger receptors on macrophages. J Immunol 154 (1995) 1-8
23. Jeannin P., Magistrelli G., Herbault N., Goetsch L., Godefroy S., Charbonnier P., et al. Outer membrane protein A renders dendritic cells and macrophages responsive to CCL21 and triggers dendritic cell migration to secondary lymphoid organs. Eur J Immunol 33 (2003) 326-333
24. Jeannin P., Renno T., Goetsch L., Miconnet I., Aubry J.P., Delneste Y., et al. OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway. Nat Immunol 1 (2000) 502-509
25. Delneste Y., Magistrelli G., Gauchat J., Haeuw J., Aubry J., Nakamura K., et al. Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity 17 (2002) 353-362
26. Areschoug T., and Gordon S. Scavenger receptors: role in innate immunity and microbial pathogenesis. Cell Microbiol 11 (2009) 1160-1169
27. Cambi A., and Figdor C.G. Levels of complexity in pathogen recognition by C-type lectins. Curr Opin Immunol 17 (2005) 345-351
28. Guermonprez P., Khelef N., Blouin E., Rieu P., Ricciardi-Castagnoli P., Guiso N., et al. The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18). J Exp Med 193 (2001) 1035-1044
29. Jeannin P., Jaillon S., and Delneste Y. Pattern recognition receptors in the immune response against dying cells. Curr Opin Immunol 20 (2008) 530-537
30. Berwin B., Delneste Y., Lovingood R.V., Post S.R., and Pizzo S.V. SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin. J Biol Chem 279 (2004) 51250-51257
31. Berwin B., Hart J.P., Rice S., Gass C., Pizzo S.V., Post S.R., et al. Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells. EMBO J 22 (2003) 6127-6136
32. Jeannin P., Bottazzi B., Sironi M., Doni A., Rusnati M., Presta M., et al. Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity 22 (2005) 551-560
33. Rock K.L. Exiting the outside world for cross-presentation. Immunity 25 (2006) 523-525
34. Green D.R., Ferguson T., Zitvogel L., and Kroemer G. Immunogenic and tolerogenic cell death. Nat Rev 9 (2009) 353-363
35. Yamasaki Y., Ikenaga T., Otsuki T., Nishikawa M., and Takakura Y. Induction of antigen-specific cytotoxic T lymphocytes by immunization with negatively charged soluble antigen through scavenger receptor-mediated delivery. Vaccine 25 (2007) 85-91
36. Theriault J.R., Adachi H., and Calderwood S.K. Role of scavenger receptors in the binding and internalization of heat shock protein 70. J Immunol 177 (2006) 8604-8611
37. Barth H., Schnober E.K., Neumann-Haefelin C., Thumann C., Zeisel M.B., Diepolder H.M., et al. Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells. J Virol 82 (2008) 3466-3479
38. Xie L., Wu X.D., Huang D.Z., Chen H.L., He L.X., Wang J., et al. Clinical application and analysis of hepatitis C virus NS3 antigen detection by ELISA in human serum. Chin Med J (Engl) 120 (2007) 294-299