-
1
-
-
80053532392
-
Hypoxia- inducible factor-1α expression and gemcitabine chemotherapy for pancreatic cancer
-
KASUYA K, TSUCHIDA A, NAGAKAWA Y, SUZUKI M, ABE Y, ITOI T, SERIZAWA H, NAGAO T, SHIMAZU M, AOKI T. Hypoxia- inducible factor-1α expression and gemcitabine chemotherapy for pancreatic cancer. Oncol Rep 2011; 26: 1399-1406.
-
(2011)
Oncol Rep
, vol.26
, pp. 1399-1406
-
-
Kasuya, K.1
Tsuchida, A.2
Nagakawa, Y.3
Suzuki, M.4
Abe, Y.5
Itoi, T.6
Serizawa, H.7
Nagao, T.8
Shimazu, M.9
Aoki, T.10
-
3
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
SEMENZA GL. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 2010; 29: 625-634.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
4
-
-
79960702572
-
Hypoxia induces tumor aggressiveness and the expansion of CD133-posi tive cells in a hypoxia-inducible factor-1α- dependent manner in pancreatic cancer cells
-
HASHIMOTO O, SHIMIZU K, SEMBA S, CHIBA S, KU Y, YOKOZAKI H, HORI Y. Hypoxia induces tumor aggressiveness and the expansion of CD133-posi tive cells in a hypoxia-inducible factor-1α- dependent manner in pancreatic cancer cells. Pathobiology 2011; 78: 181-192.
-
(2011)
Pathobiology
, vol.78
, pp. 181-192
-
-
Hashimoto, O.1
Shimizu, K.2
Semba, S.3
Chiba, S.4
Ku, Y.5
Yokozaki, H.6
Hori, Y.7
-
5
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
SEMENZA GL. Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007; 407: 8.
-
(2007)
Sci STKE
, vol.407
, pp. 8
-
-
Semenza, G.L.1
-
6
-
-
52749085519
-
Imaging of the hypoxia-inducible factor pathway: Insights into oxygen sensing
-
BERCHNER-PFANNSCHMIDT U, FREDE S, WOTZLAW C, FANDREY J. Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing. Eur Respir J 2008; 32: 210-217.
-
(2008)
Eur Respir J
, vol.32
, pp. 210-217
-
-
Berchner-Pfannschmidt, U.1
Frede, S.2
Wotzlaw, C.3
Fandrey, J.4
-
7
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
SEMENZA GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3: 3721-3732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 3721-3732
-
-
Semenza, G.L.1
-
8
-
-
79958091512
-
Hypoxia inducible factor 1, a new possible important factor in neoplasia
-
REKWIROWICZ H, MARSZALEK A. Hypoxia inducible factor 1, a new possible important factor in neoplasia. Pol J Pathol 2009; 60: 61-66.
-
(2009)
Pol J Pathol
, vol.60
, pp. 61-66
-
-
Rekwirowicz, H.1
Marszalek, A.2
-
9
-
-
60949102817
-
Hypoxia inducible factor-2á: A critical mediator of aggressive tumor phenotypes
-
QING G, SIMON MC. Hypoxia inducible factor-2á: A critical mediator of aggressive tumor phenotypes. Curr Opin Genet Dev 2009; 19: 60-66.
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 60-66
-
-
Qing, G.1
Simon, M.C.2
-
10
-
-
56149089262
-
Hypoxia inducible factor 1 and cancer pathogenesis
-
SEMENZA GL. Hypoxia inducible factor 1 and cancer pathogenesis. IUBMB Life 2008; 60: 591-597.
-
(2008)
IUBMB Life
, vol.60
, pp. 591-597
-
-
Semenza, G.L.1
-
11
-
-
1642387020
-
Hypoxia inducible factor (HIF1) [alpha]: Its protein stability and biological functions
-
LEE JW, BAE SH, JEONG JW, KIM SH, KIM KW. Hypoxia inducible factor (HIF1) [alpha]: its protein stability and biological functions. Exp Mol Med 2004; 36: 1-12.
-
(2004)
Exp Mol Med
, vol.36
, pp. 1-12
-
-
Lee, J.W.1
Bae, S.H.2
Jeong, J.W.3
Kim, S.H.4
Kim, K.W.5
-
12
-
-
77951755278
-
Pancreatic cancer
-
HIDALGO M. Pancreatic cancer. N Engl J Med 2010; 362: 1605-1617.
-
(2010)
N Engl J Med
, vol.362
, pp. 1605-1617
-
-
Hidalgo, M.1
-
13
-
-
75149136717
-
Tumor metabolism to blood flow ratio in pancreatic cancer: Helpful in patient stratification?
-
MICHALSKI CW, ERKAN M, FRIESS H, KLEEFF J. Tumor metabolism to blood flow ratio in pancreatic cancer: helpful in patient stratification? Future Oncol 2010; 6: 13-15.
-
(2010)
Future Oncol
, vol.6
, pp. 13-15
-
-
Michalski, C.W.1
Erkan, M.2
Friess, H.3
Kleeff, J.4
-
14
-
-
33748742635
-
Cross-talk between epidermal growth factor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by upregulating survivin gene expression
-
PENG XH, KARNA P, CAO Z, JIANG BH, ZHOU M, YANG L. Cross-talk between epidermal growth factor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by upregulating survivin gene expression. J Biol Chem 2006, 281: 25903-25914.
-
(2006)
J Biol Chem
, vol.281
, pp. 25903-25914
-
-
Peng, X.H.1
Karna, P.2
Cao, Z.3
Jiang, B.H.4
Zhou, M.5
Yang, L.6
-
15
-
-
84856905433
-
Role of the apoptotic and mitotic regulator survivin in melanoma
-
MCKENZIE JA, GROSSMAN D. Role of the apoptotic and mitotic regulator survivin in melanoma. Anticancer Res 2012; 32: 397-404.
-
(2012)
Anticancer Res
, vol.32
, pp. 397-404
-
-
McKenzie, J.A.1
Grossman, D.2
-
16
-
-
30944442431
-
Small interfering RNA expression vector targeting hypoxia-inducible factor-1 alpha inhibits tumor growth in hepatobiliary and pancreatic cancers
-
MIZUNO T, NAGAO M, YAMADA Y, NARIKIYO M, UENO M, MIYAQISHI M, TAIRA K, NAKAJIMA Y. Small interfering RNA expression vector targeting hypoxia-inducible factor-1 alpha inhibits tumor growth in hepatobiliary and pancreatic cancers. Cancer Gene Ther 2006; 13: 131-140.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 131-140
-
-
Mizuno, T.1
Nagao, M.2
Yamada, Y.3
Narikiyo, M.4
Ueno, M.5
Miyaqishi, M.6
Taira, K.7
Nakajima, Y.8
-
17
-
-
77951698149
-
Hypoxia-inducible factor-1- dependent mechanisms of vascularization and vascular remodeling
-
REY S, SEMENZA GL. Hypoxia-inducible factor-1- dependent mechanisms of vascularization and vascular remodeling. Cardiovascular Res 2010; 86: 236-242.
-
(2010)
Cardiovascular Res
, vol.86
, pp. 236-242
-
-
Rey, S.1
Semenza, G.L.2
-
18
-
-
82555165050
-
Coexpression of angiopoietin- 1 with VEGF increases the structural integrity of the blood-brain barrier and reduces atrophy volume
-
SHEN F, WALKER EJ, JIANG L, DEGOS V, LI J, SUN B, HERIYANTO F, YOUNG WL, SU H. Coexpression of angiopoietin- 1 with VEGF increases the structural integrity of the blood-brain barrier and reduces atrophy volume. J Cereb Blood Flow Metab. 2011, 31:2343-51.
-
(2011)
J Cereb Blood Flow Metab.
, vol.31
, pp. 2343-2351
-
-
Shen, F.1
Walker, E.J.2
Jiang, L.3
Degos, V.4
Li, J.5
Sun, B.6
Heriyanto, F.7
Young, W.L.8
Su, H.9
-
19
-
-
79957952535
-
Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
-
SEMENZA GL. Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning. Biochim Biophys Acta 2011; 1813: 1263-1268.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1263-1268
-
-
Semenza, G.L.1
-
20
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
DEBERARDINIS RJ, LUM JJ, HATZIVASSILIOU G, THOMPSON CB. The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation. Cell Metab 2008; 7: 11-20.
-
(2008)
Cell Metab
, vol.7
, pp. 11-20
-
-
Deberardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
21
-
-
35448982216
-
Hypoxia, glucose metabolism and the Warburg's effect
-
BARTRONS R, CARO J. Hypoxia, glucose metabolism and the Warburg's effect. J Bioenerg Biomembr 2007; 39: 223-229.
-
(2007)
J Bioenerg Biomembr
, vol.39
, pp. 223-229
-
-
Bartrons, R.1
Caro, J.2
-
22
-
-
60549083256
-
Regulation of cancer cell metabolism by hypoxia-inducible factor-1
-
SEMENZA GL. Regulation of cancer cell metabolism by hypoxia-inducible factor-1. Semin Cancer Biol 2009; 19: 12-16.
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 12-16
-
-
Semenza, G.L.1
-
23
-
-
34147172349
-
HIF-1-regulated glucose metabolism: A key to apoptosis resistance?
-
FULDA S, DEBATIN KM. HIF-1-regulated glucose metabolism: a key to apoptosis resistance? Cell Cycle 2007; 6: 790-792.
-
(2007)
Cell Cycle
, vol.6
, pp. 790-792
-
-
Fulda, S.1
Debatin, K.M.2
-
24
-
-
4644226319
-
Aunique pathway of cardiac myocyte death caused by hypoxia-acidosis
-
GRAHAM RM, FRAZIER DP, THOMPSON JW, HALIKO S, LI H, WASSERLAUF BJ, SPIGA MG, BISHOPRIC NH, WEBSTER KA. Aunique pathway of cardiac myocyte death caused by hypoxia-acidosis. J Exp Biol 2004; 207: 3189-3200.
-
(2004)
J Exp Biol
, vol.207
, pp. 3189-3200
-
-
Graham, R.M.1
Frazier, D.P.2
Thompson, J.W.3
Haliko, S.4
Li, H.5
Wasserlauf, B.J.6
Spiga, M.G.7
Bishopric, N.H.8
Webster, K.A.9
-
25
-
-
33846476727
-
Toxic effects of cobalt in primary culture of mouse astrocytes. Similarities with hypoxia and role of HIF-1alpha
-
KAROVIC O, TONAZZINI I, REBOLA N, EDSTROM E, LOVDAHL C, FREDHOLM BB, DARE E. Toxic effects of cobalt in primary culture of mouse astrocytes. Similarities with hypoxia and role of HIF-1alpha. Biochem Pharmacol 2007; 73: 694-708.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 694-708
-
-
Karovic, O.1
Tonazzini, I.2
Rebola, N.3
Edstrom, E.4
Lovdahl, C.5
Fredholm, B.B.6
Dare, E.7
-
26
-
-
37549036729
-
Survivin, cancer networks and pathway- directed drug discovery
-
ALTIERI DC. Survivin, cancer networks and pathway- directed drug discovery. Nat Rev Cancer 2008; 8: 61-70.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 61-70
-
-
Altieri, D.C.1
-
27
-
-
34047105144
-
Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance
-
KILIC M, KASPERCZYK H, FULDA S, DEBATIN KM. Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance. Oncogene 2007; 26: 2027-2038.
-
(2007)
Oncogene
, vol.26
, pp. 2027-2038
-
-
Kilic, M.1
Kasperczyk, H.2
Fulda, S.3
Debatin, K.M.4
-
28
-
-
77954482113
-
The antioxidant quercetin inhibits cellular proliferation via HIF-1-dependent induction of p21WAF
-
BACH A, BENDER-SIGEL J, SCHRENK D, FLUGEL D, KIETZMANN T. The antioxidant quercetin inhibits cellular proliferation via HIF-1-dependent induction of p21WAF. Antioxid Redox Signal 2010; 13: 437-448.
-
(2010)
Antioxid Redox Signal
, vol.13
, pp. 437-448
-
-
Bach, A.1
Bender-Sigel, J.2
Schrenk, D.3
Flugel, D.4
Kietzmann, T.5
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