New PLGA-P188-PLGA matrix enhances TGF-β3 release from pharmacologically active microcarriers and promotes chondrogenesis of mesenchymal stem cells

Journal of Controlled Release

Volumn 170, Issue 1, 2013, Pages 99-110

  Morille, Marie ^a,b   Van Thanh, Tran ^a   Garric, Xavier ^c   Cayon, Jérôme ^d   Coudane, Jean ^c   Noël, Danièle ^b   Venier Julienne, Marie Claire ^a   Montero Menei, Claudia N ^a  

^a UNIVERSITÉ D'ANGERS   (France)

^b INSERM   (France)

^c CNRS   (France)

^d Service Commun de Cytométrie et d'Analyse Nucléotidiques SCCAN   (France)

Author keywords

Chondrogenic differentiation; Mesenchymal stem cells; Pharmacologically active microcarriers; Protein encapsulation; Transforming growth factor

Indexed keywords

BIOACTIVITY; CARTILAGE; CELL CULTURE; CELLS; CYTOLOGY; ORGANIC POLYMERS; POLYMERS; PROTEINS; REPAIR; STEM CELLS; TISSUE; TISSUE REGENERATION;

CHONDROGENIC DIFFERENTIATION; MESENCHYMAL STEM CELL; MICROCARRIERS; PROTEIN ENCAPSULATION; TRANSFORMING GROWTH FACTORS;

SCAFFOLDS (BIOLOGY);

AGGRECAN; DRUG CARRIER; FIBRONECTIN; MICROSPHERE; MOLECULAR SCAFFOLD; PHARMACOLOGICALLY ACTIVE MICROCARRIER; POLOXAMER; POLYGLACTIN; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CHONDROGENESIS; COMPLEX FORMATION; CONTROLLED STUDY; DEGRADATION; DENATURATION; DRUG RELEASE; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN SECRETION; SURFACE PROPERTY; SUSTAINED DRUG RELEASE;

EID: 84878510629     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.04.017     Document Type: Article

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