Lentivirus IL-10 gene therapy down-regulates IL-17 and attenuates mouse orthotopic lung allograft rejection

American Journal of Transplantation

Volumn 13, Issue 6, 2013, Pages 1586-1593

  Hirayama, S ^a,b   Sato, M ^a,c   Loisel Meyer, S ^d   Matsuda, Y ^a   Oishi, H ^a   Guan, Z ^a   Saito, T ^a   Yeung, J ^a   Cypel, M ^a   Hwang, D M ^a   Medin, J A ^b   Liu, M ^a   Keshavjee, S ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b OKAYAMA ROSAI HOSPITAL   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bronchiolitis obliterans; chronic lung allograft dysfunction; lung transplantation; rejection

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; LENTIVIRUS VECTOR; LUCIFERASE; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENE THERAPY; GENE TRANSFER; HISTOPATHOLOGY; IMMUNE RESPONSE; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; GENETIC THERAPY; GRAFT REJECTION; GRAFT SURVIVAL; INTERLEUKIN-10; INTERLEUKIN-17; LENTIVIRUS; LUNG TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; RNA; TRANSPLANTATION, HOMOLOGOUS;

EID: 84878503027     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12230     Document Type: Article

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