NAAG peptidase inhibitor improves motor function and reduces cognitive dysfunction in a model of TBI with secondary hypoxia

Brain Research

Volumn 1515, Issue , 2013, Pages 98-107

  Gurkoff, Gene G ^a   Feng, Jun Feng ^a,b   Van, Ken C ^a   Izadi, Ali ^a   Ghiasvand, Rahil ^a   Shahlaie, Kiarash ^a   Song, Minsoo ^c   Lowe, David A ^c   Zhou, Jia ^d   Lyeth, Bruce G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c PSYCHOGENICS INC   (United States)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Behavior; Excitotoxicity N acetylaspartylglutamate (NAAG); Hypoxia; Pre clinical; Traumatic brain injury (TBI)

Indexed keywords

GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; PGI 02776; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN HYPOXIA; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; LATENT PERIOD; MALE; MAZE TEST; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN INJURIES; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GLUTAMATE CARBOXYPEPTIDASE II; HYPOXIA, BRAIN; MALE; MOTOR SKILLS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; UREA;

ANIMALIA; RATTUS;

EID: 84878499000     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.03.043     Document Type: Article

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