NAAG peptidase inhibitor reduces cellular damage in a model of TBI with secondary hypoxia

Brain Research

Volumn 1469, Issue , 2012, Pages 144-152

  Feng, Jun Feng ^a,b   Gurkoff, Gene G ^a   Van, Ken C ^a   Song, Minsoo ^c   Lowe, David A ^c   Zhou, Jia ^d   Lyeth, Bruce G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c PSYCHOGENICS INC   (United States)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Astrocyte; Glutamate; Hippocampus; Hypoxia; N acetylaspartylglutamate (NAAG); Neuronal degeneration; Traumatic brain injury (TBI)

Indexed keywords

GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; PGI 02776; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN HYPOXIA; BRAIN REGION; CELL DAMAGE; CONTROLLED STUDY; DENTATE GYRUS; ENZYME INHIBITION; HIPPOCAMPUS; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; ASTROCYTES; BRAIN INJURIES; CELL DEATH; CELL SHAPE; ENZYME INHIBITORS; GLUTAMATE CARBOXYPEPTIDASE II; HIPPOCAMPUS; HYPOXIA, BRAIN; MALE; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; UREA;

EID: 84864740583     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.06.021     Document Type: Article

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