High-resolution MS in regulated bioanalysis: Where are we now and where do we go from here?

Bioanalysis

Volumn 5, Issue 10, 2013, Pages 1277-1284

  Fung, Eliza N ^a   Jemal, Mohammed ^b   Aubry, Anne Françoise ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; BIOASSAY; COMPUTER PROGRAM; DATA ANALYSIS; DATA MINING; HUMAN; INSTRUMENT VALIDATION; INTERMETHOD COMPARISON; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; REVIEW; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY;

EID: 84878486782     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.81     Document Type: Review

References (34)

1. Zhang J, Maloney J, Drexler D et al. Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays. Bioanalysis 4(5), 581-593 (2012).
2. Vrbanac JJ, Hilgers A, Dubnicka T, Shilliday BF, Humphries D, Hayes RN. High-resolution isotope-dilution mass spectrometry using metabolism of isotope-labeled compounds: application to drug metabolites. Rapid Commun. Mass Spectrom. 26(22), 2569-2576 (2012).
3. Polgár L, García-Reyes JF, Fodor P et al. Retrospective screening of relevant pesticide metabolites in food using liquid chromatography high resolution mass spectrometry and accurate-mass databases of parent molecules and diagnostic fragment ions. J. Chromatogr. A 1249, 83-91 (2012).
4. Rochat B. Quantitative/qualitative analysis using LC-HRMS: the fundamental step forward for clinical laboratories and clinical practice. Bioanalysis 4 (14), 1709-1711 (2012).
5. Pinhancos R, Maass S, Ramanathan DM. High-resolution mass spectrometry method for the detection, characterization and quantitation of pharmaceuticals in water. J. Mass Spectrom. 46 (11), 1175-1181 (2011).
6. Ramanathan R, Jemal M, Ramagiri S et al. It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS. J. Mass Spectrom. 46(6), 595-601 (2011).
7. Kellmann M, Muenster H, Zomer P, Mol H. Full scan MS in comprehensive qualitative and quantitative residue analysis in food and feed matrices: how much resolving power is required? J. Am. Soc. Mass Spectrom. 20(8), 1464-1476 (2009).
8. Bateman K P, Kellmann M, Muenster H, Papp R, Taylor L. Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer. J. Am. Soc. Mass Spectrom. 20 (8), 1441-1450 (2009).
9. van der Heeft E, Bolck YJ, Beumer B et al. Full scan accurate mass selectivity of ultra-performance liquid chromatography combined with time-of-fight and Orbitrap mass spectrometry in hormone and veterinary drug residue analysis. J. Am. Soc. Mass Spectrom. 20(3), 451-463 (2008).
10. Kantharaj E, Tuytelaars A, Proost PE, Ongel Z, van Assouw HP, Gilissen RAHJ. Simultaneous measurement of drug metabolic stability and identifcation of metabolites using ion-trap mass spectrometry. Rapid Commun. Mass Spectrom. 17(23), 2661-2668 (2003).
11. Hopfgartner G, Tonoli D, Varesio E. High-resolution mass spectrometry for integrated qualitative and quantitative analysis of pharmaceuticals in biological matrices. Anal. Bioanal. Chem. 402(8), 2587-2596 (2012).
12. Meyer MR, Maurer HH. Current applications of high-resolution mass spectrometry in drug metabolism studies. Anal. Bioanal. Chem. 403(5), 1221-1231 (2012).
13. Tonoli D, Varesio E, Hopfgartner G. Quantifcation of acetaminophen and two of its metabolites in human plasma by ultra-high performance liquid chromatography-low and high resolution tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 904, 42-50 (2012).
14. Zhang NR, Yu S, Tiller P, Yeh S, Mahan E, Emary WB. Quantitation of small molecules using high-resolution accurate mass spectrometers-a different approach for analysis of biological samples. Rapid Commun. Mass Spectrom. 23, 1085-1094 (2009).
15. Lawson G, Patel P, Mulla H, Tanna S. Dried blood spot sampling with LC-MS analysis for routine therapeutic caffeine monitoring in neonates. ISRN Chromatography Article ID: 828719 (2012).
16. Fung EN, Xia YQ, Aubry AF, Zeng, J, Olah T, Jemal M. Full scan high resolution accurate mass spectrometry (HRMS) in regulated bioanalysis: LC-HRMS for the quantitation of prednisone and prednisolone in human plasma. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879(27), 2919-2927 (2011).
17. Bruce SJ, Rochat B, Béguin A, Pesse B, Guessous I, Boulet O, Henry H. Analysis and quantifcation of vitamin D metabolites in serum by ultra-performance liquid chromatography coupled to tandem mass spectrometry and high-resolution mass spectrometry-a method comparison and validation. Rapid Commun. Mass Spectrom. 27(1), 200-206 (2013).
18. Lawson G, Cock E, Tanna S. Quantitative determination of atenolol in dried blood spot samples by LC-HRMS: a potential method for assessing medication adherence. J. Chromatogr. B 897, 72-79 (2012).
19. Zurlo J, Rudacille D, Goldberg AM. The three Rs: the way forward. Environ. Health Perspect. 104(8) 878-880 (1996).
20. Fung EN, Jemal M, Lau JH, Walker RA, Olah T, Xia YQ. Comparison of full scan high resolution MS and triple quadrupole SRM in quantitative bioanalysis. Presented at: Proceedings of the 58th ASMS Conference on Mass Spectrometry and Allied Topics. Salt Lake City, U T, USA 23-27 May, 2010.
21. Xia Y, Lau J, Olah T, Jemal M. Targeted quantitative bioanalysis in plasma using liquid chromatography/high-resolution accurate mass spectrometry: an evaluation of global selectivity as a function of mass resolving power and extraction window, with comparison of centroid and profle modes. Rapid Commun. Mass Spectrom. 25, 2863-2878 (2011).
22. Rochat B, Kottelat E, McMullen J. The future key role of LC-high-resolution-MS analyses in clinical laboratories: a focus on quantifcation. Bioanalysis 4(24), 2939-2958 (2012).
23. Kaufmann A, Walker S. Evaluation of the interrelationship between mass resolving power and mass error tolerances for targeted bioanalysis using liquid chromatography coupled to high-resolution mass spectrometry. Rapid Commun. Mass Spectrom. 27(2), 347-356 (2013).
24. Kaufmann A, Butcher P, Maden K, Walker S, Widmer M. Comprehensive comparison of liquid chromatography selectivity as provided by two types of liquid chromatography detectors (high resolution mass spectrometry and tandem mass spectrometry): 'where is the crossover point?' Anal. Chim. Acta 673, 60-72 (2010).
25. Penner N, Xu L, Prakash C. Radiolabeled absorption, distribution, metabolism, and excretion studies in drug development: why, when, and how? Chem. Res. Toxicol. 25(3), 513-531 (2012).
26. Isin EM, Elmore CS, Nilsson GN, Thompson RA, Weidolf L. Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies. Chem. Res. Toxicol. 25(3), 532-542 (2012).
27. Chang MS, Ji Q, Zhang J, El-Shourbagy TA. Historical review of sample preparation for chromatographic bioanalysis: pros and cons. Drug Develop. Res. 68, 107-133 (2007).
28. Jemal M, Ouyang Z, Xia YQ. Systematic LC-MS/MS bioanalytical method development that incorporates plasma phospholipids risk avoidance, usage of incurred sample and well thought-out chromatography. Biomed. Chromatogr. 24(1) 2-19 (2010).
29. Furlong MT, Ouyang Z, Wu S, Tamura J, Olah T, Tymiak A, Jemal M. A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies. Biomed Chromatogr. 26(8), 1024-1032 (2012).
30. Ramagiri S, Garofolo F. Large molecule bioanalysis using Q-TOF without predigestion and its data processing challenges. Bioanalysis 4(5), 529-540 (2012).
31. Dillen L, Cools W, Vereyken L et al. Comparison of triple quadrupole and high-resolution TOF-MS for quantifcation of peptides. Bioanalysis 4(5), 565-579 (2012).
32. Cuyckens F, Dillen L, Cools W et al. Identifying metabolite ions of peptide drugs in the presence of an in vivo matrix background. Bioanalysis 4(5), 595-604 (2012).
33. Plumb RS, Fujimoto G, Mather J, Beguin A, Pesse B, Guessous OB, Henry H. Comparison of the quantifcation of a therapeutic protein using nominal and accurate mass MS/MS. Bioanalysis 4(5), 605-615 (2012).
34. Croley TR, White KD, Callahan JH, Musser SM, The chromatographic role in high resolution mass spectrometry for non-targeted analysis. J. Am. Soc. Mass Spectrom. 23(9), 1569-1578 (2012).