Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays

Bioanalysis

Volumn 4, Issue 5, 2012, Pages 581-593

  Zhang, Jun ^a   Maloney, Jennifer ^a   Drexler, Dieter M ^a   Cai, Xianmei ^a   Stewart, Jeremy ^a   Mayer, Chris ^a   Herbst, John ^a   Weller, Harold ^a   Shou, Wilson Z ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEBUTOLOL; BUSPIRONE; CARBAMAZEPINE; CHLORPHENIRAMINE; CHLORPROMAZINE; CLOMIPRAMINE; CLONIDINE; CLOZAPINE; DESIPRAMINE; DILTIAZEM; FLUPHENAZINE; HALOPERIDOL; IMIPRAMINE; INDOMETACIN; KETOPROFEN; METOPROLOL; MINAPRINE; NADOLOL; NEFAZODONE; NORFLOXACIN; PHENTOLAMINE; PROMETHAZINE; PROPRANOLOL; RITONAVIR; SULFADIAZINE; TIABENDAZOLE; TICLOPIDINE; TIMOLOL; UNINDEXED DRUG; VERAPAMIL;

ACCURACY; ARTICLE; ARTIFICIAL MEMBRANE; BINDING ASSAY; BIOASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG PROTEIN BINDING; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; INTERMETHOD COMPARISON; MASS SPECTROMETRY; MEMBRANE PERMEABILITY; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PROTEIN BINDING; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS;

BIOLOGICAL ASSAY; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS;

EID: 84863337845     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.2     Document Type: Article

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