Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells

Chemico-Biological Interactions

Volumn 204, Issue 2, 2013, Pages 105-115

  Hsieh, Chi Ying ^a   Tsai, Pei Chien ^a   Chu, Chiao Lun ^a   Chang, Fang Rong ^a   Chang, Long Sen ^b   Wu, Yang Chang ^c,d   Lin, Shinne Ren ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Brazilein; Migration; MMP 2; P38 MAPK; PI3K Akt

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTINEOPLASTIC AGENT; BRAZILEIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE; CELL INVASION; CELL MIGRATION; CELL STRAIN MDA MB 231; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

EID: 84878446899     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.05.005     Document Type: Article

References (37)

1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, M.J. Thun, Cancer statistics, CA Cancer J. Clin. 59 (2009) (2009) 225-249.
2. H. Nagase, J.F. Woessner Jr., Matrix metalloproteinases, J. Biol. Chem. 274 (1999) 21491-21494.
3. E.I. Deryugina, J.P. Quigley, Matrix metalloproteinases and tumor metastasis, Cancer Metastasis Rev. 25 (2006) 9-34. (Pubitemid 43723979)
4. S. Chakraborti, M. Mandal, S. Das, A. Mandal, T. Chakraborti, Regulation of matrix metalloproteinases: an overview, Mol. Cell Biochem. 253 (2003) 269-285.
5. G.S. Delassus, H. Cho, J. Park, G.L. Eliceiri, New pathway links from cancerprogression determinants to gene expression of matrix metalloproteinases in breast cancer cells, J. Cell Physiol. 217 (2008) 739-744.
6. G.L. Johnson, R. Lapadat, Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases, Science 298 (2002) 1911-1912. (Pubitemid 35425238)
7. K.B. Reddy, S.M. Nabha, N. Atanaskova, Role of MAP kinase in tumor progression and invasion, Cancer Metastasis Rev. 22 (2003) 395-403. (Pubitemid 36791895)
8. M. Qiao, S. Sheng, A.B. Pardee, Metastasis and AKT activation, Cell Cycle 7 (2008) 2991-2996.
9. M. Ye, D. Hu, L. Tu, X. Zhou, F. Lu, B. Wen, W. Wu, Y. Lin, Z. Zhou, J. Qu, Involvement of PI3K/Akt signaling pathway in hepatocyte growth factorinduced migration of uveal melanoma cells, Invest. Ophthalmol. Vis. Sci. 49 (2008) 497-504.
10. P.N. Chen, Y.S. Hsieh, H.L. Chiou, S.C. Chu, Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways, Chem. Biol. Interact. 156 (2005) 141-150.
11. I.M. Lockhart, 3-Chromanols and 4-chromanols, in: G.P. Ellis (Ed.), Chemistry of Heterocyclic Compounds Chromenes Chromanones and Chromones, John Wiley & Sons, New York, 1977, pp. 141-192.
12. C.T. Yen, K. Nakagawa-Goto, T.L. Hwang, P.C. Wu, S.L. Morris-Natschke, W.C. Lai, K.F. Bastow, F.R. Chang, Y.C. Wu, K.H. Lee, Antitumor agents 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents, Bioorg. Med. Chem. Lett. 20 (2010) 1037-1039.
13. X. Zhong, B. Wu, Y.J. Pan, S. Zheng, Brazilein inhibits survivin protein and mRNA expression and induces apoptosis in hepatocellular carcinoma HepG2 cells, Neoplasma 56 (2009) 387-392.
14. V. Betapudi, L.S. Licate, T.T. Egelhoff, Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration, Cancer Res. 66 (2006) 4725-4733.
15. D. Kim, S. Kim, H. Koh, S.O. Yoon, A.S. Chung, K.S. Cho, J. Chung, Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production, FASEB J. 15 (2001) 1953-1962. (Pubitemid 32848799)
16. K.L. Lin, J.C. Su, C.M. Chien, C.H. Tseng, Y.L. Chen, L.S. Chang, S.R. Lin, Naphtho [1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation, Toxicol. Vitro 24 (2010) 61-70.
17. B. Zhang, J. Zhang, H.Z. Huang, W.L. Chen, Q. Tao, D.L. Zeng, L.T. Zhang, J.H. Xu, Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity, J. Oral Pathol. Med. 38 (2009) 731-736.
18. J. Westermarck, V.M. Kahari, Regulation of matrix metalloproteinase expression in tumor invasion, FASEB J. 13 (1999) 781-792. (Pubitemid 29220691)
19. B. Kumar, S. Koul, J. Petersen, L. Khandrika, J.S. Hwa, R.B. Meacham, S. Wilson, H.K. Koul, P38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity, Cancer Res. 70 (2010) 832-841.
20. K.H. Shen, S.H. Hung, L.T. Yin, C.S. Huang, C.H. Chao, C.L. Liu, Y.W. Shih, Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway, Mol. Cell. Biochem. 333 (2010) 279-291.
21. Y.W. Shih, P.S. Chen, C.H. Wu, Y.F. Jeng, C.J. Wang, Alpha-chaconine- reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NFkappaB in human lung adenocarcinoma A549 cells, J. Agric. Food Chem. 55 (2007) 11035-11043.
22. K.D. Shin, M.Y. Lee, D.S. Shin, S. Lee, K.H. Son, S. Koh, Y.K. Paik, B.M. Kwon, D.C. Han, Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation, J. Biol. Chem. 280 (2005) 41439-41448. (Pubitemid 41832203)
23. D. Hanahan, R.A. Weinberg, The hallmarks of cancer, Cell 100 (2000) 57-70. (Pubitemid 30046295)
24. P.S. Steeg, Tumor metastasis: mechanistic insights and clinical challenges, Nat. Med. 12 (2006) 895-904. (Pubitemid 44175140)
25. M.J. Duffy, T.M. Maguire, A. Hill, E. McDermott, N. O'Higgins, Metalloproteinases: role in breast carcinogenesis, invasion and metastasis, Breast Cancer Res. 2 (2000) 252-257. (Pubitemid 32223594)
26. D. Sliva, Signaling pathways responsible for cancer cell invasion as targets for cancer therapy, Curr. Cancer Drug Targets 4 (2004) 327-336. (Pubitemid 38797244)
27. S. Ghosh, D. Baltimore, Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B, Nature 344 (1990) 678-682.
28. S. Ghosh, M.S. Hayden, New regulators of NF-kappa B in inflammation, Nat. Rev. Immunol. 8 (2008) 837-848.
29. Y.T. Yang, C.J. Weng, C.T. Ho, G.C. Yen, Resveratrol analog-3,5,4'- trimethoxytrans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression, Mol. Nutr. Food Res. 53 (2009) 407-416.
30. H.H. Lin, J.H. Chen, F.P. Chou, C.J. Wang, Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-kappaB pathway and MMP-2 production by targeting RhoB activation, Br. J. Pharmacol. 162 (2011) 237-254.
31. A.B. Carter, K.L. Knudtson, M.M. Monick, G.W. Hunninghake, The p38 mitogenactivated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP), J. Biol. Chem. 274 (1999) 30858-30863.
32. E.S. Kim, M.S. Kim, A. Moon, TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells, Int. J. Oncol. 25 (2004) 1375-1382.
33. M.L. Lin, Y.C. Lu, J.G. Chung, S.G. Wang, H.T. Lin, S.E. Kang, C.H. Tang, J.L. Ko, S.S. Chen, Down-regulation of MMP-2 through the p38 MAPK-NF-kappaBdependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion, Mol. Carcinog. 49 (2010) 783-797.
34. M.H. Pan, Y.S. Chiou, W.J. Chen, J.M. Wang, V. Badmaev, C.T. Ho, Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells, Carcinogenesis 30 (2009) 1234-1242.
35. Y.C. Lee, H.H. Lin, C.H. Hsu, C.J. Wang, T.A. Chiang, J.H. Chen, Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway, Eur. J. Pharmacol. 632 (2010) 23-32.
36. Y. Nakamura, C. Yoshida, A. Murakami, H. Ohigashi, T. Osawa, K. Uchida, Zerumbone, atropical ginger sesquiterpene, activates phase II drug metabolizing enzymes, FEBS Lett. 572 (2004) 245-250. (Pubitemid 39092543)
37. K. Umemura, T. Itoh, N. Hamada, Y. Fujita, Y. Akao, Y. Nozawa, N. Matsuura, M. Iinuma, M. Ito, Preconditioning by sesquiterpene lactone enhances H2O2-induced Nrf2/ARE activation, Biochem. Biophys. Res. Commun. 368 (2008) 948-954.