메뉴 건너뛰기




Volumn 345, Issue 6, 2013, Pages 470-477

The expression of intermediate filament protein nestin and its association with cyclin-dependent kinase 5 in the glomeruli of rats with diabetic nephropathy

Author keywords

Cyclin dependent kinase 5; Diabetic nephropathy; Nestin; Roscovitine; Vimentin

Indexed keywords

CYCLIN DEPENDENT KINASE 5; MESSENGER RNA; NESTIN; ROSCOVITINE; STREPTOZOCIN; VIMENTIN;

EID: 84878431008     PISSN: 00029629     EISSN: 15382990     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e3182648459     Document Type: Conference Paper
Times cited : (19)

References (42)
  • 1
    • 35848931880 scopus 로고    scopus 로고
    • Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: Role in the development of diabetic glomerular disease
    • Menini S, Iacobini C, Oddi G, et al. Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: role in the development of diabetic glomerular disease. Diabetologia 2007;50:2591-9.
    • (2007) Diabetologia , vol.50 , pp. 2591-2599
    • Menini, S.1    Iacobini, C.2    Oddi, G.3
  • 2
    • 70349251778 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and podocyte loss in diabetic kidney disease
    • Reidy K, Susztak K. Epithelial-mesenchymal transition and podocyte loss in diabetic kidney disease. Am J Kidney Dis 2009;54:590-3.
    • (2009) Am J Kidney Dis , vol.54 , pp. 590-593
    • Reidy, K.1    Susztak, K.2
  • 3
    • 70349263307 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy
    • Yamaguchi Y, Lwano M, Suzuki D, et al. Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy. Am J Kidney Dis 2009;54:653-64.
    • (2009) Am J Kidney Dis , vol.54 , pp. 653-664
    • Yamaguchi, Y.1    Lwano, M.2    Suzuki, D.3
  • 4
    • 70349487338 scopus 로고    scopus 로고
    • Hypertrophy and loss of podocytes in diabetic nephropathy
    • Miyauchi M, Toyoda M, Kobayashi K, et al. Hypertrophy and loss of podocytes in diabetic nephropathy. Intern Med 2009;48:1615-20.
    • (2009) Intern Med , vol.48 , pp. 1615-1620
    • Miyauchi, M.1    Toyoda, M.2    Kobayashi, K.3
  • 5
    • 80052516404 scopus 로고    scopus 로고
    • Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury
    • Fuchshofer R, Ullmann S, Zeilbeck LF, et al. Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury. Histochem Cell Biol 2011;136:301-19.
    • (2011) Histochem Cell Biol , vol.136 , pp. 301-319
    • Fuchshofer, R.1    Ullmann, S.2    Zeilbeck, L.F.3
  • 6
    • 73949138025 scopus 로고    scopus 로고
    • Newly identified cytoskeletal components are associated with dynamic changes of podocyte foot processes
    • Miao J, Fan Q, Cui Q, et al. Newly identified cytoskeletal components are associated with dynamic changes of podocyte foot processes. Nephrol Dial Transplant 2009;24:3297-305.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 3297-3305
    • Miao, J.1    Fan, Q.2    Cui, Q.3
  • 7
    • 56949105292 scopus 로고    scopus 로고
    • Mechanisms of angiotensin II signaling on cytoskeleton of podocytes
    • Hsu HH, Hoffmann S, Endlich N, et al. Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. J MolMed (Berl) 2008;86:1379-94.
    • (2008) J MolMed (Berl) , vol.86 , pp. 1379-1394
    • Hsu, H.H.1    Hoffmann, S.2    Endlich, N.3
  • 8
    • 0025190642 scopus 로고
    • CNS stem cells express a new class of intermediate filament protein
    • Lendahl U, Zimmerman LB, McKay RD. CNS stem cells express a new class of intermediate filament protein. Cell 1990;60:585-95.
    • (1990) Cell , vol.60 , pp. 585-595
    • Lendahl, U.1    Zimmerman, L.B.2    McKay, R.D.3
  • 9
    • 0034728764 scopus 로고    scopus 로고
    • Nestin-expressing cells in the pancreatic islets of Langerhans
    • Hunziker E, Stein M. Nestin-expressing cells in the pancreatic islets of Langerhans. Biochem Biophys Res Commun 2000;271:116-9.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 116-119
    • Hunziker, E.1    Stein, M.2
  • 10
    • 0027990629 scopus 로고
    • Myogenesis and the intermediate filament protein, nestin
    • Kachinsky AM, Dominov JA, Miller JB. Myogenesis and the intermediate filament protein, nestin. Dev Biol 1994;165:216-28.
    • (1994) Dev Biol , vol.165 , pp. 216-228
    • Kachinsky, A.M.1    Dominov, J.A.2    Miller, J.B.3
  • 11
    • 0029148229 scopus 로고
    • Intermediate filaments in cardiac myogenesis: Nestin in the developing mouse heart
    • Kachinsky AM, Dominov JA, Miller JB. Intermediate filaments in cardiac myogenesis: nestin in the developing mouse heart. J Histochem Cytochem 1995;43:843-7.
    • (1995) J Histochem Cytochem , vol.43 , pp. 843-847
    • Kachinsky, A.M.1    Dominov, J.A.2    Miller, J.B.3
  • 12
    • 0043193868 scopus 로고    scopus 로고
    • Nestin expression in hair follicle sheath progenitor cells
    • Li L, Mignone J, Yang M, et al. Nestin expression in hair follicle sheath progenitor cells. Proc Natl Acad Sci U S A 2003;100:9958-61.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9958-9961
    • Li, L.1    Mignone, J.2    Yang, M.3
  • 13
    • 33646376214 scopus 로고    scopus 로고
    • Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes
    • Chen J, Boyle S, Zhao M, et al. Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes. J Am Soc Nephrol 2006;17:1283-91.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1283-1291
    • Chen, J.1    Boyle, S.2    Zhao, M.3
  • 14
    • 33947585554 scopus 로고    scopus 로고
    • Nestin expression in adult and developing human kidney
    • Bertelli E, Regoli M, Fonzi L, et al. Nestin expression in adult and developing human kidney. J Histochem Cytochem 2007;55:411-21.
    • (2007) J Histochem Cytochem , vol.55 , pp. 411-421
    • Bertelli, E.1    Regoli, M.2    Fonzi, L.3
  • 15
    • 34248229649 scopus 로고    scopus 로고
    • Expression of nestin in the podocytes of normal and diseased human kidneys
    • Su W, Chen J, Yang H, et al. Expression of nestin in the podocytes of normal and diseased human kidneys. Am J Physiol Regul Integr Comp Physiol 2007;292:R1761-7.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Su, W.1    Chen, J.2    Yang, H.3
  • 17
    • 0038450245 scopus 로고    scopus 로고
    • Cdk5 regulates the organization of Nestin and its association with p35
    • Sahlgren CM, Mikhailov A, Vaittinen S, et al. Cdk5 regulates the organization of Nestin and its association with p35. Mol Cell Biol 2003; 23:5090-106.
    • (2003) Mol Cell Biol , vol.23 , pp. 5090-5106
    • Sahlgren, C.M.1    Mikhailov, A.2    Vaittinen, S.3
  • 18
    • 33750223900 scopus 로고    scopus 로고
    • A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death
    • Sahlgren CM, Pallari HM, He T, et al. A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death. EMBO J 2006;25: 4808-19.
    • (2006) EMBO J , vol.25 , pp. 4808-4819
    • Sahlgren, C.M.1    Pallari, H.M.2    He, T.3
  • 19
    • 0030781307 scopus 로고    scopus 로고
    • Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist
    • Pippin JW, Qu Q, Meijer L, et al. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist. J Clin Invest 1997;100:2512-20.
    • (1997) J Clin Invest , vol.100 , pp. 2512-2520
    • Pippin, J.W.1    Qu, Q.2    Meijer, L.3
  • 20
    • 0024506896 scopus 로고
    • Formation of extracellular matrix by cultured rat mesangial cells
    • Ishimura E, Sterzel RB, Budde K, et al. Formation of extracellular matrix by cultured rat mesangial cells. Am J Pathol 1989;134:843-55.
    • (1989) Am J Pathol , vol.134 , pp. 843-855
    • Ishimura, E.1    Sterzel, R.B.2    Budde, K.3
  • 21
    • 54049131227 scopus 로고    scopus 로고
    • Establishment of conditionally immortalized mouse glomerular parietal epithelial cells in culture
    • Ohse T, Pippin JW, Vaughan MR, et al. Establishment of conditionally immortalized mouse glomerular parietal epithelial cells in culture. J Am Soc Nephrol 2008;19:1879-90.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1879-1890
    • Ohse, T.1    Pippin, J.W.2    Vaughan, M.R.3
  • 22
    • 2442680120 scopus 로고    scopus 로고
    • Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL
    • de Zeeuw D, Remuzzi G, Parving HH, et al. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int 2004;65:2309-20.
    • (2004) Kidney Int , vol.65 , pp. 2309-2320
    • De Zeeuw, D.1    Remuzzi, G.2    Parving, H.H.3
  • 23
    • 0035008793 scopus 로고    scopus 로고
    • Glomerular cell number in normal subjects and in type 1 diabetic patients
    • Steffes MW, Schmidt D, McCrery R, et al. Glomerular cell number in normal subjects and in type 1 diabetic patients. Kidney Int 2001;59:2104-13.
    • (2001) Kidney Int , vol.59 , pp. 2104-2113
    • Steffes, M.W.1    Schmidt, D.2    McCrery, R.3
  • 24
    • 0031029379 scopus 로고    scopus 로고
    • Podocyte loss and progressive glomerular injury in type II diabetes
    • Pagtalunan ME, Miller PL, Jumping-Eagle S, et al. Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest 1997;99:342-48.
    • (1997) J Clin Invest , vol.99 , pp. 342-348
    • Pagtalunan, M.E.1    Miller, P.L.2    Jumping-Eagle, S.3
  • 25
    • 0032710966 scopus 로고    scopus 로고
    • Podocyte number predicts longterm urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria
    • Meyer TW, Bennett PH, Nelson RG. Podocyte number predicts longterm urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria. Diabetologia 1999;42:1341-4.
    • (1999) Diabetologia , vol.42 , pp. 1341-1344
    • Meyer, T.W.1    Bennett, P.H.2    Nelson, R.G.3
  • 26
    • 0037381607 scopus 로고    scopus 로고
    • Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes
    • Dalla Vestra M, Masiero A, Roiter AM, et al. Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes. Diabetes 2003;52:1031-5.
    • (2003) Diabetes , vol.52 , pp. 1031-1035
    • Dalla Vestra, M.1    Masiero, A.2    Roiter, A.M.3
  • 27
    • 33646918846 scopus 로고    scopus 로고
    • IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes
    • Peters I, Tossidou I, Achenbach J, et al. IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes. J Am Soc Nephrol 2006;17:1644-56.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1644-1656
    • Peters, I.1    Tossidou, I.2    Achenbach, J.3
  • 28
    • 27944453588 scopus 로고    scopus 로고
    • Actin cytoskeleton regulates extracellular matrix-dependent survival signals in glomerular epithelial cells
    • Bijian K, Takano T, Papillon J, et al. Actin cytoskeleton regulates extracellular matrix-dependent survival signals in glomerular epithelial cells. Am J Physiol Renal Physiol 2005;289:F1313-23.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Bijian, K.1    Takano, T.2    Papillon, J.3
  • 29
    • 0032559341 scopus 로고    scopus 로고
    • A structural scaffolding of intermediate filaments in health and disease
    • Fuchs E, Cleveland DW. A structural scaffolding of intermediate filaments in health and disease. Science 1998;279:514-9.
    • (1998) Science , vol.279 , pp. 514-519
    • Fuchs, E.1    Cleveland, D.W.2
  • 30
    • 62149122940 scopus 로고    scopus 로고
    • Impaired tubular uptake explains albuminuria in early diabetic nephropathy
    • Russo LM, Sandoval RM, Campos SB, et al. Impaired tubular uptake explains albuminuria in early diabetic nephropathy. J Am Soc Nephrol 2009;20:489-94.
    • (2009) J Am Soc Nephrol , pp. 489-494
    • Russo, L.M.1    Sandoval, R.M.2    Campos, S.B.3
  • 31
    • 33847011714 scopus 로고    scopus 로고
    • Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: Amelioration by soluble TGF-beta type II receptor
    • Russo LM, del Re E, Brown D, et al. Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes 2007;56:380-8.
    • (2007) Diabetes , vol.56 , pp. 380-388
    • Russo, L.M.1    Del Re, E.2    Brown, D.3
  • 32
    • 33645577952 scopus 로고    scopus 로고
    • Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury
    • Zou J, Yaoita E, Watanabe Y, et al. Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch 2006; 448:485-92.
    • (2006) Virchows Arch , vol.448 , pp. 485-492
    • Zou, J.1    Yaoita, E.2    Watanabe, Y.3
  • 33
    • 20844461871 scopus 로고    scopus 로고
    • Angiotensin II receptor blocker inhibits p27Kip1 expression in glucose-stimulated podocytes and in diabetic glomeruli
    • Xu ZG, Yoo TH, Ryu DR, et al. Angiotensin II receptor blocker inhibits p27Kip1 expression in glucose-stimulated podocytes and in diabetic glomeruli. Kidney Int 2005;67:944-52.
    • (2005) Kidney Int , vol.67 , pp. 944-952
    • Xu, Z.G.1    Yoo, T.H.2    Ryu, D.R.3
  • 34
    • 10944270563 scopus 로고    scopus 로고
    • Mechanical stretch induces podocyte hypertrophy in vitro
    • Petermann AT, Pippin J, Durvasula R, et al. Mechanical stretch induces podocyte hypertrophy in vitro. Kidney Int 2005;67:157-66.
    • (2005) Kidney Int , vol.67 , pp. 157-166
    • Petermann, A.T.1    Pippin, J.2    Durvasula, R.3
  • 35
    • 33748459960 scopus 로고    scopus 로고
    • Intermediate filament protein nestin is expressed in developing kidney and heart and might be regulated by the Wilms' tumor suppressor Wt1
    • Wagner N, Wagner KD, Scholz H, et al. Intermediate filament protein nestin is expressed in developing kidney and heart and might be regulated by the Wilms' tumor suppressor Wt1. Am J Physiol Regul Integr Comp Physiol 2006;291:779-87.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291 , pp. 779-787
    • Wagner, N.1    Wagner, K.D.2    Scholz, H.3
  • 36
    • 0026452774 scopus 로고
    • Neuronal cdc2-like kinase: A cdc2-related protein kinase with predominantly neuronal expression
    • Hellmich MR, Pant HC, Wada E, et al. Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression. Proc Natl Acad Sci U S A 1992;89:10867-71.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10867-10871
    • Hellmich, M.R.1    Pant, H.C.2    Wada, E.3
  • 37
    • 79955485558 scopus 로고    scopus 로고
    • Nestin as a regulator of Cdk5 in differentiating myoblasts
    • Pallari HM, Lindqvist J, Torvaldson E, et al. Nestin as a regulator of Cdk5 in differentiating myoblasts. Mol Biol Cell 2011;22:1539-49.
    • (2011) Mol Biol Cell , vol.22 , pp. 1539-1549
    • Pallari, H.M.1    Lindqvist, J.2    Torvaldson, E.3
  • 38
    • 4644273096 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology
    • Griffin SV, Hiromura K, Pippin J, et al. Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology. Am J Pathol 2004;165:1175-85.
    • (2004) Am J Pathol , vol.165 , pp. 1175-1185
    • Griffin, S.V.1    Hiromura, K.2    Pippin, J.3
  • 39
    • 3142660506 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca (2+)-dependent exocytosis
    • Lilja L, Johansson JU, Gromada J, et al. Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis. J Biol Chem 2004;279:29534-41.
    • (2004) J Biol Chem , vol.279 , pp. 29534-29541
    • Lilja, L.1    Johansson, J.U.2    Gromada, J.3
  • 40
    • 27144441483 scopus 로고    scopus 로고
    • Cdk5-dependent regulation of glucose-stimulated insulin secretion
    • Wei FY, Nagashima K, Ohshima T, et al. Cdk5-dependent regulation of glucose-stimulated insulin secretion. Nat Med 2005;11:1104-8.
    • (2005) Nat Med , vol.11 , pp. 1104-1108
    • Wei, F.Y.1    Nagashima, K.2    Ohshima, T.3
  • 41
    • 58149089468 scopus 로고    scopus 로고
    • CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation
    • Okada S, Yamada E, Saito T, et al. CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation. J Biol Chem 2008;283:35455-63.
    • (2008) J Biol Chem , vol.283 , pp. 35455-35463
    • Okada, S.1    Yamada, E.2    Saito, T.3
  • 42
    • 63149115282 scopus 로고    scopus 로고
    • The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes
    • Lalioti V, Muruais G, Dinarina A, et al. The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A 2009;106:4249-53.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4249-4253
    • Lalioti, V.1    Muruais, G.2    Dinarina, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.