Nestin as a regulator of Cdk5 in differentiating myoblasts

Molecular Biology of the Cell

Volumn 22, Issue 9, 2011, Pages 1539-1549

  Pallari, Hanna Mari ^a,b   Lindqvist, Julia ^a,b   Torvaldson, Elin ^a,b   Ferraris, Saima E ^a,b   He, Tao ^c   Sahlgren, Cecilia ^a,b   Eriksson, John E ^a,b  

^a UNIVERSITY OF TURKU   (Finland)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MYOGENIN; MYOSIN HEAVY CHAIN; NESTIN; PROTEIN P25; PROTEIN P35;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOUSE; MUSCLE DEVELOPMENT; MUSCLE TISSUE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; HUMANS; INTERMEDIATE FILAMENT PROTEINS; MICE; MUSCLE DEVELOPMENT; MYOBLASTS; NERVE TISSUE PROTEINS; PHOSPHOTRANSFERASES; POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 79955485558     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-07-0568     Document Type: Article

References (44)

1. Bieberich E, MacKinnon S, Silva J, Noggle S, Condie BG (2003). Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide. J Cell Biol 162, 469-479. (Pubitemid 36988555)
2. Buckingham M, Bajard L, Chang T, Daubas P, Hadchouel J, Meilhac S, Montarras D, Rocancourt D, Relaix F (2003). The formation of skeletal muscle: from somite to limb. J Anat 202, 59-68. (Pubitemid 36503969)
3. Colucci-Guyon E, Portier MM, Dunia I, Paulin D, Pournin S, Babinet C (1994). Mice lacking vimentin develop and reproduce without an obvious phenotype. Cell 79, 679-694. (Pubitemid 24363811)
4. Eliasson C, Sahlgren C, Berthold CH, Stakeberg J, Celis JE, Betsholtz C, Eriksson JE, Pekny M (1999). Intermediate filament protein partnership in astrocytes. J Biol Chem 274, 23996-24006.
5. Eriksson JE, Dechat T, Grin B, Helfand B, Mendez M, Pallari HM, Goldman RD (2009). Introducing intermediate filaments: from discovery to disease. J Clin Invest 119, 1763-1771.
6. Fischer A, Sananbenesi F, Pang PT, Lu B, Tsai LH (2005). Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron 48, 825-838.
7. Fu AK, Fu WY, Cheung J, Tsim KW, Ip FC, Wang JH, Ip NY (2001). Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction. Nat Neurosci 4, 374-381. (Pubitemid 32260113)
8. Fu AK, Ip FC, Fu WY, Cheung J, Wang JH, Yung WH, Ip NY (2005). Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice. Proc Natl Acad Sci USA 102, 15224-15229. (Pubitemid 41513363)
9. Huang C, Rajfur Z, Yousefi N, Chen Z, Jacobson K, Ginsberg MH (2009). Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration. Nat Cell Biol 11, 624-630.
10. Hyder CL, Pallari HM, Kochin V, Eriksson JE (2008). Providing cellular signposts - post-translational modifications of intermediate filaments. FEBS Lett 582, 2140-2148.
11. Ikiz B, Przedborski S (2008). A sequel to the tale of p25/Cdk5 in neurodegeneration. Neuron 60, 731-732.
12. Inagaki M, Nishi Y, Nishizawa K, Matsuyama M, Sato C (1987). Site-specific phosphorylation induces disassembly of vimentin filaments in vitro. Nature 328, 649-652. (Pubitemid 17103974)
13. Jing R, Wilhelmsson U, Goodwill W, Li L, Pan Y, Pekny M, Skalli O (2007). Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks. J Cell Sci 120, 1267-1277. (Pubitemid 46711845)
14. Kamei H, Saito T, Ozawa M, Fujita Y, Asada A, Bibb JA, Saido TC, Sorimachi H, Hisanaga S (2007). Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation. J Biol Chem 282, 1687-1694. (Pubitemid 47076684)
15. Kawamoto M, Ishiwata T, Cho K, Uchida E, Korc M, Naito Z, Tajiri T (2009). Nestin expression correlates with nerve and retroperitoneal tissue invasion in pancreatic cancer. Hum Pathol 40, 189-198.
16. Kim D et al. (2008). Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron 60, 803-817.
17. Kinouchi R, Takeda M, Yang L, Wilhelmsson U, Lundkvist A, Pekny M, Chen DF (2003). Robust neural integration from retinal transplants in mice deficient in GFAP and vimentin. Nat Neurosci 6, 863-868. (Pubitemid 36929708)
18. Kitzmann M, Fernandez A (2001). Crosstalk between cell cycle regulators and the myogenic factor MyoD in skeletal myoblasts. Cell Mol Life Sci 58, 571-579. (Pubitemid 32382258)
19. Kleeberger W, Bova GS, Nielsen ME, Herawi M, Chuang AY, Epstein JI, Berman DM (2007). Roles for the stem cell associated intermediate filament Nestin in prostate cancer migration and metastasis. Cancer Res 67, 9199-9206. (Pubitemid 47535906)
20. Lazaro JB, Kitzmann M, Poul MA, Vandromme M, Lamb NJ, Fernandez A (1997). Cyclin dependent kinase 5, cdk5, is a positive regulator of myogenesis in mouse C2 cells. J Cell Sci 110, 1251-1260. (Pubitemid 27254399)
21. Lee JH, Kim HS, Lee SJ, Kim KT (2007). Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death. J Cell Sci 120, 2259-2271.
22. Lendahl U, Zimmerman LB, McKay RD (1990). CNS stem cells express a new class of intermediate filament protein. Cell 60, 585-595.
23. Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF (2005). Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron 46, 569-579. (Pubitemid 40797382)
24. Liu C, Chen B, Zhu J, Zhang R, Yao F, Jin F, Xu H, Lu P (2010). Clinical implications for nestin protein expression in breast cancer. Cancer Sci 101, 815-819.
25. Odemis V, Boosmann K, Dieterlen MT, Engele J (2007). The chemokine SDF1 controls multiple steps of myogenesis through atypical PKCzeta. J Cell Sci 120, 4050-4059. (Pubitemid 350269410)
26. -/- neurons in the developing cerebellum is cell autonomous. J Neurosci 19, 6017-6026.
27. Ohshima T, Ward JM, Huh CG, Longenecker G, Veeranna Pant HC, Brady RO, Martin LJ, Kulkarni AB (1996). Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc Natl Acad Sci USA 93, 11173-11178. (Pubitemid 26333137)
28. Pallari HM, Eriksson JE (2006). Intermediate filaments as signaling platforms. Sci STKE 366, pe53.
29. Pekny M, Lane EB (2007). Intermediate filaments and stress. Exp Cell Res 313, 2244-2254. (Pubitemid 46850731)
30. Philpott A, Porro EB, Kirschner MW, Tsai LH (1997). The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning. Genes Dev 11, 1409-1421. (Pubitemid 27259852)
31. Potokar M, Stenovec M, Gabrijel M, Li L, Kreft M, Grilc S, Pekny M, Zorec R (2010). Intermediate filaments attenuate stimulation-dependent mobility of endosomes/lysosomes in astrocytes. Glia 58, 1208-1219.
32. Reimer R, Helmbold H, Szalay B, Hagel C, Hohenberg H, Deppert W, Bohn W (2009). Nestin modulates glucocorticoid receptor function by cytoplasmic anchoring. PLoS One 4, e6084.
33. Rochlin K, Yu S, Roy S, Baylies MK (2010). Myoblast fusion: when it takes more to make one. Dev Biol 341, 66-83.
34. Sahlgren CM, Mikhailov A, Vaittine S, Pallari HM, Kalimo H, Pant HC, Eriksson JE (2003). Cdk5 regulates the organization of Nestin and its association with p35. Mol Cell Biol 23, 5090-5106. (Pubitemid 36793352)
35. Sahlgren CM, Pallari HM, He T, Chou YH, Goldman RD, Eriksson JE (2006). A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death. EMBO J 25, 4808-4819. (Pubitemid 44607026)
36. Schabort EJ, Van Der Merwe M, Loos B, Moore FP, Niesler CU (2009). TGF-beta's delay skeletal muscle progenitor cell differentiation in an isoform-independent manner. Exp Cell Res 315, 373-384.
37. Sejersen T, Lendahl U (1993). Transient expression of the intermediate filament nestin during skeletal muscle development. J Cell Sci 106, 1291-1300. (Pubitemid 24018414)
38. Shi X, Garry DJ (2006). Muscle stem cells in development, regeneration, and disease. Genes Dev 20, 1692-1708. (Pubitemid 43992877)
39. Steinert PM, Chou YH, Prahlad V, Parry DA, Marekov LN, Wu KC, Jang SI, Goldman RD (1999). A high molecular weight intermediate filament-associated protein in BHK-21 cells is nestin, a type VI intermediate filament protein. Limited co-assembly in vitro to form heteropolymers with type III vimentin and type IV alpha-internexin. J Biol Chem 274, 1657-1666.
40. Sun L, Ma K, Wang H, Xiao F, Gao Y, Zhang W, Wang K, Gao X, Ip N, Wu Z (2007). JAK1-STAT1-STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts. J Cell Biol 179, 129-138. (Pubitemid 47606689)
41. de Thonel A, Ferraris SE, Pallari HM, Imanishi SY, Hosokawa T, Hisanga S, Sahlgren C, Eriksson JE (2010). Protein kinase Czeta regulates Cdk5/p25 signaling during myogenesis. Mol Biol Cell 21, 1423-1434.
42. Vaittinen S, Lukka R, Sahlgren C, Rantanen J, Hurme T, Lendahl U, Eriksson JE, Kalimo H (1999). Specific and innervation-regulated expression of the intermediate filament protein nestin at neuromuscular and myotendinous junctions in skeletal muscle. Am J Pathol 154, 591-600. (Pubitemid 29094108)
43. Wakamatsu Y, Nakamura N, Lee JA, Cole GJ, Osumi N (2007). Transitin, a nestin-like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells. Development 134, 2425-2433. (Pubitemid 47074137)
44. Yang XH, Wu QL, Yu XB, Xu CX, Ma BF, Zhang XM, Li SN, Lahn BT, Xiang AP (2008). Nestin expression in different tumours and its relevance to malignant grade. J Clin Pathol 61, 467-473. (Pubitemid 351518229)