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Volumn 36, Issue 2, 2013, Pages 347-357

Cardioprotective effect of cannabidiol in rats exposed to doxorubicin toxicity

Author keywords

Cannabidiol; Doxorubicin cardiotoxicity; Inflammation; Oxidative stress; Rats

Indexed keywords

CALCIUM ION; CANNABIDIOL; CASPASE 3; CREATINE KINASE MB; DOXORUBICIN; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; NITRIC OXIDE; SELENIUM; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA; ZINC ION;

EID: 84878402214     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2013.04.018     Document Type: Article
Times cited : (82)

References (39)
  • 1
    • 33746964412 scopus 로고    scopus 로고
    • Myocardial expression of survivin, an apoptosis inhibitor, in aging and heart failure: an experimental study in the spontaneously hypertensive rat
    • Abbate A., Scarpa S., Santini D., Palleiro J., Vasaturo F., Miller J., Morales C., Vetrovec G.W., Baldi A. Myocardial expression of survivin, an apoptosis inhibitor, in aging and heart failure: an experimental study in the spontaneously hypertensive rat. Int. J. Cardiol. 2006, 113:371-376.
    • (2006) Int. J. Cardiol. , vol.113 , pp. 371-376
    • Abbate, A.1    Scarpa, S.2    Santini, D.3    Palleiro, J.4    Vasaturo, F.5    Miller, J.6    Morales, C.7    Vetrovec, G.W.8    Baldi, A.9
  • 2
    • 33750611276 scopus 로고    scopus 로고
    • The case for survivin as a regulator of microtubule dynamics and cell-death decisions
    • Altieri D.C. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. Curr. Opin. Cell Biol. 2006, 18:609-615.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 609-615
    • Altieri, D.C.1
  • 8
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
    • Blake D.R., Robson P., Ho M., Jubb R.W., McCabe C.S. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford) 2006, 45:50-52.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 50-52
    • Blake, D.R.1    Robson, P.2    Ho, M.3    Jubb, R.W.4    McCabe, C.S.5
  • 9
    • 33646734889 scopus 로고    scopus 로고
    • Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression
    • Carrier E.J., Auchampach J.A., Hillard C.J. Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:7895-7900.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 7895-7900
    • Carrier, E.J.1    Auchampach, J.A.2    Hillard, C.J.3
  • 10
    • 33645771759 scopus 로고    scopus 로고
    • Interrelations between oxidative stress and calcineurin in the attenuation of cardiac apoptosis by eugenol
    • Choudhary R., Mishra K.P., Subramanyam C. Interrelations between oxidative stress and calcineurin in the attenuation of cardiac apoptosis by eugenol. Mol. Cell. Biochem. 2006, 283:115-122.
    • (2006) Mol. Cell. Biochem. , vol.283 , pp. 115-122
    • Choudhary, R.1    Mishra, K.P.2    Subramanyam, C.3
  • 12
    • 1642268380 scopus 로고    scopus 로고
    • Oral anti-inflammatory activity of cannabidiol, a nonpsychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw
    • Costa B., Colleoni M., Conti S., Parolaro D., Franke C., Trovato A.E., Giagnoni G. Oral anti-inflammatory activity of cannabidiol, a nonpsychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw. Naunyn-Schmiedeberg's Arch. Pharmacol. 2004, 369:294-299.
    • (2004) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.369 , pp. 294-299
    • Costa, B.1    Colleoni, M.2    Conti, S.3    Parolaro, D.4    Franke, C.5    Trovato, A.E.6    Giagnoni, G.7
  • 13
    • 77249107540 scopus 로고    scopus 로고
    • 2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels
    • 2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. J. Neuroimmune. Pharmacol. 2010, 5:103-121.
    • (2010) J. Neuroimmune. Pharmacol. , vol.5 , pp. 103-121
    • De Petrocellis, L.1    Di Marzo, V.2
  • 15
    • 80054719125 scopus 로고    scopus 로고
    • Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats
    • Fouad A.A., Jresat I. Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. Eur. J. Pharmacol. 2011, 670:216-223.
    • (2011) Eur. J. Pharmacol. , vol.670 , pp. 216-223
    • Fouad, A.A.1    Jresat, I.2
  • 16
    • 69549103071 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition and angiotensin AT(1)-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity
    • Ibrahim M.A., Ashour O.M., Ibrahim Y.F., El-Bitar H.I., Gomaa W., Abdel-Rahim S.R. Angiotensin-converting enzyme inhibition and angiotensin AT(1)-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity. Pharmacol. Res. 2009, 60:373-381.
    • (2009) Pharmacol. Res. , vol.60 , pp. 373-381
    • Ibrahim, M.A.1    Ashour, O.M.2    Ibrahim, Y.F.3    El-Bitar, H.I.4    Gomaa, W.5    Abdel-Rahim, S.R.6
  • 18
    • 40849123983 scopus 로고    scopus 로고
    • Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress
    • Jiang B., Zhang L., Li M., Wu W., Yang M., Wang J., Guo D. Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress. Food Chem. Toxicol. 2008, 46:1510-1515.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 1510-1515
    • Jiang, B.1    Zhang, L.2    Li, M.3    Wu, W.4    Yang, M.5    Wang, J.6    Guo, D.7
  • 19
    • 22544466964 scopus 로고    scopus 로고
    • Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium
    • Kalivendi S.V., Konorev E.A., Cunningham S., Vanamala S.K., Kaji E.H., Joseph J., Kalyanaraman B. Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. Biochem. J. 2005, 389:527-539.
    • (2005) Biochem. J. , vol.389 , pp. 527-539
    • Kalivendi, S.V.1    Konorev, E.A.2    Cunningham, S.3    Vanamala, S.K.4    Kaji, E.H.5    Joseph, J.6    Kalyanaraman, B.7
  • 23
    • 57449115374 scopus 로고    scopus 로고
    • Adriamycin induces myocardium apoptosis through activation of nuclear factor kappaB in rat
    • Li S.E., Yu M.B. Adriamycin induces myocardium apoptosis through activation of nuclear factor kappaB in rat. Mol. Biol. Rep. 2008, 35:489-494.
    • (2008) Mol. Biol. Rep. , vol.35 , pp. 489-494
    • Li, S.E.1    Yu, M.B.2
  • 25
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G., Menna P., Salvatorelli E., Cairo G., Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev. 2004, 56:185-229.
    • (2004) Pharmacol. Rev. , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 26
    • 0027947675 scopus 로고
    • New insights into the regulation of inducible nitric oxide synthesis
    • Morris S.M., Billiar T.R. New insights into the regulation of inducible nitric oxide synthesis. Am. J. Physiol. 1994, 266:E829-E839.
    • (1994) Am. J. Physiol. , vol.266
    • Morris, S.M.1    Billiar, T.R.2
  • 27
  • 28
    • 62449330864 scopus 로고    scopus 로고
    • Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death
    • Pan H., Mukhopadhyay P., Rajesh M., Patel V., Mukhopadhyay B., Gao B., Hasko G., Pacher P. Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death. J. Pharmacol. Exp. Ther. 2009, 328:708-714.
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , pp. 708-714
    • Pan, H.1    Mukhopadhyay, P.2    Rajesh, M.3    Patel, V.4    Mukhopadhyay, B.5    Gao, B.6    Hasko, G.7    Pacher, P.8
  • 30
    • 34247327455 scopus 로고    scopus 로고
    • The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury
    • Rooney J.P. The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury. Toxicology 2007, 234:145-156.
    • (2007) Toxicology , vol.234 , pp. 145-156
    • Rooney, J.P.1
  • 31
    • 78651456305 scopus 로고    scopus 로고
    • Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study
    • Ruiz-Valdepeñas L., Martínez-Orgado J.A., Benito C., Millán A., Tolón R.M., Romero J. Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study. J. Neuroinflammation 2011, 8:5.
    • (2011) J. Neuroinflammation , vol.8 , pp. 5
    • Ruiz-Valdepeñas, L.1    Martínez-Orgado, J.A.2    Benito, C.3    Millán, A.4    Tolón, R.M.5    Romero, J.6
  • 33
    • 0034578520 scopus 로고    scopus 로고
    • Renal toxicity caused by cisplatinum in glutathione-depleted metallothionein-null mice
    • Satoh M., Shimada A., Zhang B., Tohyama C. Renal toxicity caused by cisplatinum in glutathione-depleted metallothionein-null mice. Biochem. Pharmacol. 2000, 60:1729-1734.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1729-1734
    • Satoh, M.1    Shimada, A.2    Zhang, B.3    Tohyama, C.4
  • 34
    • 0034815485 scopus 로고    scopus 로고
    • Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy
    • Sayed-Ahmed M.M., Khattab M.M., Gad M.Z., Osman A.M. Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy. Pharmacol. Toxicol. 2001, 89:140-144.
    • (2001) Pharmacol. Toxicol. , vol.89 , pp. 140-144
    • Sayed-Ahmed, M.M.1    Khattab, M.M.2    Gad, M.Z.3    Osman, A.M.4
  • 35
    • 0032563825 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy
    • Singal P.K., Iliskovic N. Doxorubicin-induced cardiomyopathy. N. Engl. J. Med. 1998, 339:900-905.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 900-905
    • Singal, P.K.1    Iliskovic, N.2
  • 36
    • 77953198702 scopus 로고    scopus 로고
    • Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion
    • Walsh S.K., Hepburn C.Y., Kane K.A., Wainwright C.L. Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. Br. J. Pharmacol. 2010, 160:1234-1242.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 1234-1242
    • Walsh, S.K.1    Hepburn, C.Y.2    Kane, K.A.3    Wainwright, C.L.4
  • 37
    • 80053470121 scopus 로고    scopus 로고
    • Electrocardiographic and biochemical evidence for the cardioprotective effect of antioxidants in acute doxorubicin-induced cardiotoxicity in the beagle dogs
    • Xin Y., Zhang S., Gu L., Liu S., Gao H., You Z., Zhou G., Wen L., Yu J., Xuan Y. Electrocardiographic and biochemical evidence for the cardioprotective effect of antioxidants in acute doxorubicin-induced cardiotoxicity in the beagle dogs. Biol. Pharm. Bull. 2011, 34:1523-1526.
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 1523-1526
    • Xin, Y.1    Zhang, S.2    Gu, L.3    Liu, S.4    Gao, H.5    You, Z.6    Zhou, G.7    Wen, L.8    Yu, J.9    Xuan, Y.10
  • 38
    • 79151471705 scopus 로고    scopus 로고
    • Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles
    • Yang Y., Gao Y., Chen L., Huang Y., Li Y. Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles. Int. J. Pharm. 2011, 405:188-195.
    • (2011) Int. J. Pharm. , vol.405 , pp. 188-195
    • Yang, Y.1    Gao, Y.2    Chen, L.3    Huang, Y.4    Li, Y.5
  • 39
    • 77953527629 scopus 로고    scopus 로고
    • Sensitization of osteosarcoma cell line SaOS-2 to chemotherapy by downregulating survivin
    • Zou J., Gan M., Mao N., Zhu X., Shi Q., Yang H. Sensitization of osteosarcoma cell line SaOS-2 to chemotherapy by downregulating survivin. Arch. Med. Res. 2010, 41:162-169.
    • (2010) Arch. Med. Res. , vol.41 , pp. 162-169
    • Zou, J.1    Gan, M.2    Mao, N.3    Zhu, X.4    Shi, Q.5    Yang, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.