Adriamycin induces myocardium apoptosis through activation of nuclear factor κB in rat

Molecular Biology Reports

Volumn 35, Issue 4, 2008, Pages 489-494

  Li, Shufeng ^a   E, Mingyan ^a   Yu, Bo ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Adriamycin; Apoptosis; Myocardium; Nuclear factor B

Indexed keywords

DOXORUBICIN; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; GEL MOBILITY SHIFT ASSAY; HEART MUSCLE; HEART MUSCLE INJURY; IMMUNOHISTOCHEMISTRY; MALE; NICK END LABELING; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; WESTERN BLOTTING;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; DOXORUBICIN; IMMUNOHISTOCHEMISTRY; MALE; MYOCARDIUM; NF-KAPPA B; PHOSPHORYLATION; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 57449115374     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-007-9112-4     Document Type: Article

References (27)

1. A Morabito D Gattuso SC Stani 2004 Safety and activity of the combination of pegylated liposomal Doxorubicin and weekly docetaxel in advanced breast cancer Breast Cancer Res Treat 86 249 257
2. N Novitzky V Thomas L Abrahams C Toit M Donald 2004 Increasing dose intensity of anthracycline antibiotics improves outcome in patients with acute myelogenous leukemia Am J Hematol 76 319 329
3. O Hequet QH Le I Moullet 2004 Subclinical late cardiomyopathy after doxorubicin therapy for lymphoma in adults J Clin Oncol 22 1864 1871
4. SE Lipshultz N Rifai VM Dalton 2004 The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia N Engl J Med 351 145 153
5. JA Olli S Antti P Kari K Markku P Martti V-P Liisa-Maria 2000 Acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosis Cancer Res 60 1789 1792
6. T Nakamura Y Ueda Y Juan S Katsuda H Takahashi E Koh 2000 Fas-mediated apoptosis in adriamycin-induced cardiomyopathy in rats: in vivo study Circulation 102 572 578
7. H Lou I Danelisen PK Singal 2005 Involvement of mitogen-activated protein kinases in adriamycin-induced cardiomyopathy Am J Physiol Heart Circ Physiol 288 H1925 H1930
8. DN Muller R Dechend E Mervaala 2000 NF-κB inhibition ameliorates angiotensin II-induced inflammatory damage in rats Hypertension 35 193 201
9. RA Beswick H Zhang D Marable JD Catravas WD Hill RC Webb 2001 Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response Hypertension 37 781 786
10. SB Kim JS Kim JH Lee WJ Yoon DS Lee MS Ko BS Kwon DH Choi HR Cho BJ Lee DK Chung HW Lee JW Park 2006 NF-κB activation is required for cisplatin-induced apoptosis in head and neck squamous carcinoma cells FEBS Lett 580 311 318
11. ZZ Chong F Li K Maiese 2005 Erythropoietin requires NF-κB and its nuclear translocation to prevent early and late apoptotic neuronal injury during beta-amyloid toxicity Curr Neurovasc Res 2 387 399
12. S Zhou CM Palmeira KB Wallace 2001 Doxorubicin-induced persistent oxidative stress to cardiac myocytes Toxicol Lett 121 151 157
13. G Koutinos GP Stathopoulos I Dontas 2002 The effect of doxorubicin and its analogue mitoxantrone on cardiac muscle and on serum lipids: an experimental study Anticancer Res 22 815 820
14. S Mukherjee SK Banerjee M Maulik AK Dinda KK Talwar SK Maulik 2003 Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-α expression BMC Pharmacol 3 16
15. HE Mohamed ME Asker SI Ali TM Fattah 2004 Protection against doxorubicin cardiomyopathy in rats: role of phosphodiesterase inhibitors type 4 Pharm Pharmacol 56 757 768
16. TV Dudnakova VL Lakomkin VG Tsyplenkova BV Shekhonin VP Shirinsky VI Kapelko 2003 Alterations in myocardial cytoskeletal and regulatory protein expression following a single Doxorubicin injection J Cardiovasc Pharmacol 41 788 794
17. M RVitelli A Filippelli B Rinaldi 2002 Effects of docosahexaenoic acid on [Ca(2+)](i) increase induced by doxorubicin in ventricular rat cardiomyocytes Life Sci 71 1905 1916
18. S Zhou LJ Heller KB Wallace 2001 Interference with calcium-dependent mitochondrial bioenergetics in cardiac myocytes isolated from doxorubicin-treated rats Toxicol Appl Pharmacol 175 60 67
19. S Wu YS Ko MS Teng 2002 Adriamycin-induced cardiomyocyte and endothelial cell apoptosis: in vitro and in vivo studies J Mol Cell Cardiol 34 1595 1607
20. W Zhao L Lu SS Chen Y Sun 2004 Temporal and spatial characteristics of apoptosis in the infarcted rat heart Biochem Biophys Res Commun 325 605 611
21. L Somerville JG Cory 2000 Enhanced roscovitine-induced apoptosis is mediated by a caspase-3-like activity in deoxyadenosine-resistant mouse leukemia L1210 cells Anticancer Res 20 3347 3355
22. E Jimi I Nakamura T Ikebe S Akiyama N Takahashi T Suda 1998 Activation of NF-κB is involved in the survival of osteoclasts promoted by interleukin-1 J Biol Chem 273 8799 8805
23. TR Bakker D Reed T Renno CV Jongeneel 1999 Efficient adenoviral transfer of NF-κB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis Int J Cancer 80 320 323
24. A Arlt J Vorndamm M Breitenbroich UR Folsch H Kalthoff WE Schmidt H Schafer 2001 Inhibition of NF-κB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin Oncogene 20 859 868
25. M Sumitomo M Tachibana C Ozu H Asakura M Murai M Hayakawa H Nakamura A Takayanagi N Shimizu 1999 Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IκBα overexpression Hum Gene Ther 10 37 47
26. MA Sovak RE Bellas DW Kim GJ Zanieski AE Rogers AM Traish GE Sonenshein 1997 Aberrant nuclear factor-κB/Rel expression and the pathogenesis of breast cancer J Clin Invest 100 2952 2960
27. Y Higuchi K Otsu K Nishida S Hirotani H Nakayama O Yamaguchi Y Matsumura H Ueno M Tada M Hori 2002 Involvement of reactive oxygen species-mediated NF-κB activation in TNF-alpha-induced cardiomyocyte hypertrophy J Mol Cell Cardiol 34 233 240