Hodgkin lymphoma-associated hemophagocytic syndrome: A disorder strongly correlated with Epstein-Barr virus

Clinical Infectious Diseases

Volumn 47, Issue 4, 2008, Pages 531-534

  Ménard, Fanny ^a,b,c   Besson, Caroline ^a,c   Rincé, Patricia ^a,b,c   Lambotte, Olivier ^a,b,d   Lazure, Thierry ^a,b,e,f   Canioni, Danielle ^e   Hermine, Olivier ^g,h,i,j   Brousset, Pierre ^k   Martin, Antoine ^l   Gaulard, Philippe ^b,m,n,o,p,q   Raphaël, Martine ^a,b,c,f   Larroche, Claire ^m,n,o,p  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b INSERM   (France)

^c Service d'Hématologie et Immunologie Biologique Cytogénétique   (France)

^d Service de Médecine Interne et Maladies Infectieuses   (France)

^e Service d'Anatomie et Cytologie Pathologiques   (France)

^f BICÊTRE HOSPITAL   (France)

^g Service d'Hématologie Adultes   (France)

^h HÔPITAL NECKER ENFANTS MALADES   (France)

ⁱ LIPADE   (France)

^j CNRS   (France)

^k CHU PURPAN   (France)

^l Service d'Anatomie et de Cytologie Pathologiques   (France)

^m Service de Médecine Interne   (France)

ⁿ UNIVERSITÉ PARIS 13   (France)

^o Département de Pathologie   (France)

^p HENRI MONDOR HOSPITAL   (France)

^q UNIVERSITÉ PARIS EST CRÉTEIL   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; EPSTEIN BARR VIRUS; FEMALE; HEMOPHAGOCYTIC SYNDROME; HISTOLOGY; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNE DEFICIENCY; LYMPHOCYTE DEPLETION; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEX RATIO; VIRUS DETECTION;

ADULT; AGED; AGED, 80 AND OVER; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HODGKIN DISEASE; HUMANS; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; MIDDLE AGED;

EID: 48749102603     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/590152     Document Type: Article

References (16)

1. Verbsky J, Grossman W. Hemophagocytic lymphohistiocytosis: diagnosis, pathophysiology, treatment, and future perspectives. Ann Med 2006; 38:20-31.
2. Janka GE. Familial and acquired hemophagocytic lymphohistiocytosis. Eur J Pediatr 2007; 166:95-109.
3. Rouphael NG, Talati NJ, Vaughan C, Cunningham K, Moreira R, Gould C. Infections associated with haemophagocytic syndrome. Lancet Infect Dis 2007; 12:814-22.
4. Lay JD, Chuang SE, Rowe M, Su IJ. Epstein-Barr virus latent membrane protein-1 mediates upregulation of tumor necrosis factor-α in EBV-infected T cells: implications for the pathogenesis of hemophagocytic syndrome. J Biomed Sci 2003; 10:146-55.
5. Han AR, Lee HR, Park BB, et al. Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome. Ann Hematol 2007; 86:493-8.
6. Kojima H, Takei N, Mukai Y, et al. Hemophagocytic syndrome as the primary clinical symptom of Hodgkin's disease. Ann Hematol 2003; 82:53-6.
7. Preciado MV, De Matteo E, Fallo A, Chabay P, Drelichman G, Grinstein S. EBV-associated Hodgkin's disease in an HIV-infected child presenting with a hemophagocytic syndrome. Leuk Lymphoma 2001; 42:231-4.
8. Dawson L, den Ottolander GJ, Kluin PM, Leeksma O. Reactive hemophagocytic syndrome as a presenting feature of Hodgkin's disease. Ann Hematol 2000; 79:322-6.
9. Chim CS, Hui PK. Reactive hemophagocytic syndrome and Hodgkin's disease. Am J Hematol 1997; 55:49-50.
10. Hasselblom S, Linde A, Riddel B. Hodgkin's lymphoma, Epstein-Barr virus reactivation and fatal hemophagocytic syndrome. J Intern Med 2004; 255:289-95.
11. Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007; 48:124-31.
12. O'Carroll DI, McKenna RW, Brunning RD. Bone marrow manifestations of Hodgkin's disease. Cancer 1976; 38:1717-28.
13. Jarrett RF, Stark GL, White J, et al.; Scotland and Newcastle Epidemiology of Hodgkin Disease Study Group. Impact of tumor Epstein-Barr virus status on presenting features and outcome in age-defined subgroups of patients with classic Hodgkin lymphoma: a population-based study. Blood 2005; 106:2444-51.
14. Bellas C, Santon A, Manzanal A, et al. Pathological, immunological, and molecular features of Hodgkin's disease associated with HIV infection: comparison with ordinary Hodgkin's disease. Am J Surg Pathol 1996; 20:1520-4.
15. Trimèche M, Bonnet C, Korbi S, Boniver J, De Leval L. Association between Epstein Barr virus and Hodgkin's lymphoma in Belgium: a pathological and virological study. Leuk Lymphoma 2007; 48:1323-31.
16. Rigaud S, Fondaneche MC, Lambert N, et al. XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome. Nature 2006; 444:110-4.