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Volumn 37, Issue 6, 2013, Pages 1008-1015

The feasibility and cost of neonatal screening for prenatal alcohol exposure by measuring phosphatidylethanol in dried blood spots

Author keywords

Alcohol; Biomarkers; Guthrie Cards; Newborn Screening; Pregnancy

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; FATTY ACID ESTER; PHOSPHATIDYLETHANOLAMINE;

EID: 84878380379     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12045     Document Type: Article
Times cited : (49)

References (51)
  • 1
    • 0034241795 scopus 로고    scopus 로고
    • Fetal alcohol syndrome and alcohol-related neurodevelopmental disorders
    • American Academy of Pediatrics
    • American Academy of Pediatrics (2000) Fetal alcohol syndrome and alcohol-related neurodevelopmental disorders. Pediatrics 106:358-361.
    • (2000) Pediatrics , vol.106 , pp. 358-361
  • 2
    • 58849085584 scopus 로고    scopus 로고
    • ACOG Committee Opinion No. 422: at-risk drinking and illicit drug use: ethical issues in obstetric and gynecologic practice
    • American College of Obstetricians and Gynecologists
    • American College of Obstetricians and Gynecologists (2008) ACOG Committee Opinion No. 422: at-risk drinking and illicit drug use: ethical issues in obstetric and gynecologic practice. Obstet Gynecol 112:1449-1460.
    • (2008) Obstet Gynecol , vol.112 , pp. 1449-1460
  • 3
    • 33748684153 scopus 로고    scopus 로고
    • Prevalence of risk factors for adverse pregnancy outcomes during pregnancy and the preconception period-United States, 2002-2004
    • Anderson JE, Ebrahim S, Floyd L, Atrash H (2006) Prevalence of risk factors for adverse pregnancy outcomes during pregnancy and the preconception period-United States, 2002-2004. Matern Child Health J 10:S101-S106.
    • (2006) Matern Child Health J , vol.10
    • Anderson, J.E.1    Ebrahim, S.2    Floyd, L.3    Atrash, H.4
  • 4
    • 33745684382 scopus 로고    scopus 로고
    • Phosphatidylethanol (PEth) concentrations in blood are correlated to reported alcohol intake in alcohol-dependent patients
    • Aradottir S, Asanovska G, Gjerss S, Hansson P, Alling C (2006) Phosphatidylethanol (PEth) concentrations in blood are correlated to reported alcohol intake in alcohol-dependent patients. Alcohol Alcohol 41:431-437.
    • (2006) Alcohol Alcohol , vol.41 , pp. 431-437
    • Aradottir, S.1    Asanovska, G.2    Gjerss, S.3    Hansson, P.4    Alling, C.5
  • 5
    • 9244246337 scopus 로고    scopus 로고
    • Phosphatidylethanol in human organs and blood: a study on autopsy material and influences by storage conditions
    • Aradottir S, Seidl S, Wurst FM, Jonsson BA, Alling C (2004) Phosphatidylethanol in human organs and blood: a study on autopsy material and influences by storage conditions. Alcohol Clin Exp Res 28:1718-1723.
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 1718-1723
    • Aradottir, S.1    Seidl, S.2    Wurst, F.M.3    Jonsson, B.A.4    Alling, C.5
  • 6
    • 0033781673 scopus 로고    scopus 로고
    • Fetal alcohol syndrome (FAS) primary prevention through FAS diagnosis: I. Identification of high-risk birth mothers through the diagnosis of their children
    • Astley SJ, Bailey D, Talbot C, Clarren SK (2000) Fetal alcohol syndrome (FAS) primary prevention through FAS diagnosis: I. Identification of high-risk birth mothers through the diagnosis of their children. Alcohol Alcohol 35:499-508.
    • (2000) Alcohol Alcohol , vol.35 , pp. 499-508
    • Astley, S.J.1    Bailey, D.2    Talbot, C.3    Clarren, S.K.4
  • 7
    • 84867821420 scopus 로고    scopus 로고
    • Advanced gestational age increases serum carbohydrate-deficient transferrin levels in abstinent pregnant women
    • Bakhireva L, Cano S, Rayburn WF, Savich R, Leeman L, Anton RF, Savage D (2012a) Advanced gestational age increases serum carbohydrate-deficient transferrin levels in abstinent pregnant women. Alcohol Alcohol 47:683-687.
    • (2012) Alcohol Alcohol , vol.47 , pp. 683-687
    • Bakhireva, L.1    Cano, S.2    Rayburn, W.F.3    Savich, R.4    Leeman, L.5    Anton, R.F.6    Savage, D.7
  • 8
    • 84878398453 scopus 로고    scopus 로고
    • Validity and feasibility of neonatal screening for prenatal alcohol exposure by measuring phosphatidylethanol in dried blood spots of a newborn
    • abstract 0129
    • Bakhireva L, Savich R, Cano S, Goff C, Annett R, Rayburn W, Savage D (2012b) Validity and feasibility of neonatal screening for prenatal alcohol exposure by measuring phosphatidylethanol in dried blood spots of a newborn. Alcohol Clin Exp Res Suppl 36:43A (abstract 0129).
    • (2012) Alcohol Clin Exp Res Suppl , vol.36
    • Bakhireva, L.1    Savich, R.2    Cano, S.3    Goff, C.4    Annett, R.5    Rayburn, W.6    Savage, D.7
  • 9
    • 66149121439 scopus 로고    scopus 로고
    • Alcohol use among pregnant and nonpregnant women of childbearing age - United States, 1991-2005
    • Center for Disease Control and Prevention
    • Center for Disease Control and Prevention (2009) Alcohol use among pregnant and nonpregnant women of childbearing age - United States, 1991-2005. MMWR Morb Mortal Wkly Rep 58:529-532.
    • (2009) MMWR Morb Mortal Wkly Rep , vol.58 , pp. 529-532
  • 10
    • 84878405799 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute
    • 5th ed. CLSI publication LA4-A5, in Series Blood collection on filter paper for newborn screening programs; approved standard. 5th ed. CLSI publication LA4-A5, Vol. CLSI, Wayne, PA.
    • Clinical and Laboratory Standards Institute (2007) Blood Collection on Filter Paper for Newborn Screening Programs; Approved Standard. 5th ed. CLSI publication LA4-A5, in Series Blood collection on filter paper for newborn screening programs; approved standard. 5th ed. CLSI publication LA4-A5, Vol. 27. CLSI, Wayne, PA.
    • (2007) Blood Collection on Filter Paper for Newborn Screening Programs; Approved Standard , vol.27
  • 13
    • 84865583599 scopus 로고    scopus 로고
    • Drug testing for newborn exposure to illicit substances in pregnancy: pitfalls and pearls
    • Farst KJ, Valentine JL, Hall RW (2011) Drug testing for newborn exposure to illicit substances in pregnancy: pitfalls and pearls. Int J Pediatr 2011:951616.
    • (2011) Int J Pediatr , vol.2011 , pp. 951616
    • Farst, K.J.1    Valentine, J.L.2    Hall, R.W.3
  • 15
    • 84865960196 scopus 로고    scopus 로고
    • Formation of phosphatidylethanol and its subsequent elimination during an extensive drinking experiment over 5 days
    • Gnann H, Weinmann W, Thierauf A (2012) Formation of phosphatidylethanol and its subsequent elimination during an extensive drinking experiment over 5 days. Alcohol Clin Exp Res 36:1507-1511.
    • (2012) Alcohol Clin Exp Res , vol.36 , pp. 1507-1511
    • Gnann, H.1    Weinmann, W.2    Thierauf, A.3
  • 16
    • 78649629523 scopus 로고    scopus 로고
    • Rates of fetal alcohol exposure among newborns in a high-risk obstetric unit
    • Goh YI, Hutson JR, Lum L, Roukema H, Gareri J, Lynn H, Koren G (2010) Rates of fetal alcohol exposure among newborns in a high-risk obstetric unit. Alcohol 44:629-634.
    • (2010) Alcohol , vol.44 , pp. 629-634
    • Goh, Y.I.1    Hutson, J.R.2    Lum, L.3    Roukema, H.4    Gareri, J.5    Lynn, H.6    Koren, G.7
  • 17
    • 34547296452 scopus 로고    scopus 로고
    • Bioanalytical procedures for monitoring in utero drug exposure
    • Gray T, Huestis M (2007) Bioanalytical procedures for monitoring in utero drug exposure. Anal Bioanal Chem 388:1455-1465.
    • (2007) Anal Bioanal Chem , vol.388 , pp. 1455-1465
    • Gray, T.1    Huestis, M.2
  • 18
    • 0026610809 scopus 로고
    • Gamma-glutamyltransferase, aspartate and alanine aminotransferases and their ratio, mean cell volume and urinary dolichol in pregnant alcohol abusers
    • Halmesmaki E, Roine R, Salaspuro M (1992) Gamma-glutamyltransferase, aspartate and alanine aminotransferases and their ratio, mean cell volume and urinary dolichol in pregnant alcohol abusers. Br J Obstet Gynaecol 99:287-291.
    • (1992) Br J Obstet Gynaecol , vol.99 , pp. 287-291
    • Halmesmaki, E.1    Roine, R.2    Salaspuro, M.3
  • 21
    • 0018290009 scopus 로고
    • Fetal erythrocyte lifespan
    • Harrison KL (1979) Fetal erythrocyte lifespan. Aust Paediatr J 15:96-97.
    • (1979) Aust Paediatr J , vol.15 , pp. 96-97
    • Harrison, K.L.1
  • 22
    • 33947182580 scopus 로고    scopus 로고
    • Phosphatidylethanol as a sensitive and specific biomarker: comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydrate-deficient transferrin
    • Hartmann S, Aradottir S, Graf M, Wiesbeck G, Lesch O, Ramskogler K, Wolfersdorf M, Alling C, Wurst FM (2007) Phosphatidylethanol as a sensitive and specific biomarker: comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydrate-deficient transferrin. Addict Biol 12:81-84.
    • (2007) Addict Biol , vol.12 , pp. 81-84
    • Hartmann, S.1    Aradottir, S.2    Graf, M.3    Wiesbeck, G.4    Lesch, O.5    Ramskogler, K.6    Wolfersdorf, M.7    Alling, C.8    Wurst, F.M.9
  • 23
    • 84865340269 scopus 로고    scopus 로고
    • Monitoring of the alcohol biomarkers PEth, CDT and EtG/EtS in an outpatient treatment setting
    • Helander A, Peter O, Zheng Y (2012) Monitoring of the alcohol biomarkers PEth, CDT and EtG/EtS in an outpatient treatment setting. Alcohol Alcohol 47:552-557.
    • (2012) Alcohol Alcohol , vol.47 , pp. 552-557
    • Helander, A.1    Peter, O.2    Zheng, Y.3
  • 24
    • 67650081281 scopus 로고    scopus 로고
    • Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS
    • Helander A, Zheng Y (2009) Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS. Clin Chem 55:1395-1405.
    • (2009) Clin Chem , vol.55 , pp. 1395-1405
    • Helander, A.1    Zheng, Y.2
  • 26
    • 84863066896 scopus 로고    scopus 로고
    • Neonatal drug withdrawal
    • Hudak ML, Tan RC (2012) Neonatal drug withdrawal. Pediatrics 129:e540-e560.
    • (2012) Pediatrics , vol.129
    • Hudak, M.L.1    Tan, R.C.2
  • 27
  • 28
    • 79959694858 scopus 로고    scopus 로고
    • The detection of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol in human dried blood spots
    • Jones J, Jones M, Plate C, Lewis D (2011) The detection of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol in human dried blood spots. Anal Methods 3:1101-1106.
    • (2011) Anal Methods , vol.3 , pp. 1101-1106
    • Jones, J.1    Jones, M.2    Plate, C.3    Lewis, D.4
  • 30
    • 78650513424 scopus 로고    scopus 로고
    • Changes in transferrin glycosylation during pregnancy may lead to false-positive carbohydrate-deficient transferrin (CDT) results in testing for riskful alcohol consumption
    • Kenan N, Larsson A, Axelsson O, Helander A (2011) Changes in transferrin glycosylation during pregnancy may lead to false-positive carbohydrate-deficient transferrin (CDT) results in testing for riskful alcohol consumption. Clin Chim Acta 412:129-133.
    • (2011) Clin Chim Acta , vol.412 , pp. 129-133
    • Kenan, N.1    Larsson, A.2    Axelsson, O.3    Helander, A.4
  • 31
    • 0031021205 scopus 로고    scopus 로고
    • Detection of intrauterine illicit drug exposure by newborn drug testing. National Academy of Clinical Biochemistry
    • Kwong TC, Ryan RM (1997) Detection of intrauterine illicit drug exposure by newborn drug testing. National Academy of Clinical Biochemistry. Clin Chem 43:235-242.
    • (1997) Clin Chem , vol.43 , pp. 235-242
    • Kwong, T.C.1    Ryan, R.M.2
  • 32
    • 33846045535 scopus 로고    scopus 로고
    • Detection of alcohol consumption during pregnancy-current and future biomarkers
    • Littner Y, Bearer CF (2007) Detection of alcohol consumption during pregnancy-current and future biomarkers. Neurosci Biobehav Rev 31:261-269.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 261-269
    • Littner, Y.1    Bearer, C.F.2
  • 34
    • 35148834735 scopus 로고    scopus 로고
    • Is meconium screening appropriate for universal use? Science and ethics say no
    • Marcellus L (2007) Is meconium screening appropriate for universal use? Science and ethics say no. Adv Neonatal Care 7:207-214.
    • (2007) Adv Neonatal Care , vol.7 , pp. 207-214
    • Marcellus, L.1
  • 35
    • 38849113202 scopus 로고    scopus 로고
    • What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research
    • McDade TW, Williams S, Snodgrass JJ (2007) What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research. Demography 44:899-925.
    • (2007) Demography , vol.44 , pp. 899-925
    • McDade, T.W.1    Williams, S.2    Snodgrass, J.J.3
  • 36
    • 0037232958 scopus 로고    scopus 로고
    • Prevalence of fatty acid ethyl esters in meconium specimens
    • Moore C, Jones J, Lewis D, Buchi K (2003) Prevalence of fatty acid ethyl esters in meconium specimens. Clin Chem 49:133-136.
    • (2003) Clin Chem , vol.49 , pp. 133-136
    • Moore, C.1    Jones, J.2    Lewis, D.3    Buchi, K.4
  • 37
    • 84878400041 scopus 로고    scopus 로고
    • New Mexico Department of Health The state of health in New Mexico. Available at: Accessed July 15, 2012.
    • New Mexico Department of Health (2011) The state of health in New Mexico. Available at: http://nmhealth.org/CommunicationsOffice/2010%20News%20Releases/SoH%202011%20for%20download%20FINAL.pdf. Accessed July 15, 2012.
    • (2011)
  • 38
    • 0026502669 scopus 로고
    • Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study
    • Ostrea EM Jr, Brady M, Gause S, Raymundo AL, Stevens M (1992) Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study. Pediatrics 89:107-113.
    • (1992) Pediatrics , vol.89 , pp. 107-113
    • Ostrea Jr, E.M.1    Brady, M.2    Gause, S.3    Raymundo, A.L.4    Stevens, M.5
  • 39
    • 70149092314 scopus 로고    scopus 로고
    • Intervention for individuals with fetal alcohol spectrum disorders: treatment approaches and case management
    • Paley B, O'Connor MJ (2009) Intervention for individuals with fetal alcohol spectrum disorders: treatment approaches and case management. Dev Disabil Res Rev 15:258-267.
    • (2009) Dev Disabil Res Rev , vol.15 , pp. 258-267
    • Paley, B.1    O'Connor, M.J.2
  • 40
    • 0034064243 scopus 로고    scopus 로고
    • Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse
    • Sarkola T, Eriksson CJ, Niemela O, Sillanaukee P, Halmesmaki E (2000) Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse. Acta Obstet Gynecol Scand 79:359-366.
    • (2000) Acta Obstet Gynecol Scand , vol.79 , pp. 359-366
    • Sarkola, T.1    Eriksson, C.J.2    Niemela, O.3    Sillanaukee, P.4    Halmesmaki, E.5
  • 41
    • 77749283228 scopus 로고    scopus 로고
    • Phosphatidylethanol and alcohol consumption in reproductive age women
    • Steward S, Law T, Randall P, Newman R (2010) Phosphatidylethanol and alcohol consumption in reproductive age women. Alcohol Clin Exp Res 34:488-492.
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 488-492
    • Steward, S.1    Law, T.2    Randall, P.3    Newman, R.4
  • 42
    • 70249089999 scopus 로고    scopus 로고
    • Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension
    • Stewart SH, Reuben A, Brzezinski WA, Koch DG, Basile J, Randall PK, Miller PM (2009) Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. Alcohol Alcohol 44:464-467.
    • (2009) Alcohol Alcohol , vol.44 , pp. 464-467
    • Stewart, S.H.1    Reuben, A.2    Brzezinski, W.A.3    Koch, D.G.4    Basile, J.5    Randall, P.K.6    Miller, P.M.7
  • 44
    • 84878409331 scopus 로고    scopus 로고
    • Advances in the management of meconium aspiration syndrome
    • Swarnam K, Soraisham AS, Sivanandan S (2012) Advances in the management of meconium aspiration syndrome. Int J Pediatr 2012:359571.
    • (2012) Int J Pediatr , vol.2012 , pp. 359571
    • Swarnam, K.1    Soraisham, A.S.2    Sivanandan, S.3
  • 45
    • 84878383054 scopus 로고    scopus 로고
    • What is sensitivity analysis? Hayward Medical Communications, Hayward Group Ltd. Available at: Accessed July 30, 2012.
    • Taylor M (2009) What is sensitivity analysis? Hayward Medical Communications, Hayward Group Ltd. Available at: http://www.whatisseries.co.uk/whatis/. Accessed July 30, 2012.
    • (2009)
    • Taylor, M.1
  • 46
    • 0036670351 scopus 로고    scopus 로고
    • Formation of phosphatidylethanol in vitro in red blood cells from healthy volunteers and chronic alcoholics
    • Varga A, Alling C (2002) Formation of phosphatidylethanol in vitro in red blood cells from healthy volunteers and chronic alcoholics. J Lab Clin Med 140:79-83.
    • (2002) J Lab Clin Med , vol.140 , pp. 79-83
    • Varga, A.1    Alling, C.2
  • 47
    • 0033949285 scopus 로고    scopus 로고
    • Normalization rate and cellular localization of phosphatidylethanol in whole blood from chronic alcoholics
    • Varga A, Hansson P, Johnson G, Alling C (2000) Normalization rate and cellular localization of phosphatidylethanol in whole blood from chronic alcoholics. Clin Chim Acta 299:141-150.
    • (2000) Clin Chim Acta , vol.299 , pp. 141-150
    • Varga, A.1    Hansson, P.2    Johnson, G.3    Alling, C.4
  • 48
    • 80053637385 scopus 로고    scopus 로고
    • Implementing a perinatal substance abuse screening tool
    • Wallman CM, Smith PB, Moore K (2011) Implementing a perinatal substance abuse screening tool. Adv Neonatal Care 11:255-267.
    • (2011) Adv Neonatal Care , vol.11 , pp. 255-267
    • Wallman, C.M.1    Smith, P.B.2    Moore, K.3
  • 50
    • 84865982599 scopus 로고    scopus 로고
    • False-positive meconium test results for fatty acid ethyl esters secondary to delayed sample collection
    • Zelner I, Hutson JR, Kapur BM, Feig DS, Koren G (2012a) False-positive meconium test results for fatty acid ethyl esters secondary to delayed sample collection. Alcohol Clin Exp Res 36:1497-1506.
    • (2012) Alcohol Clin Exp Res , vol.36 , pp. 1497-1506
    • Zelner, I.1    Hutson, J.R.2    Kapur, B.M.3    Feig, D.S.4    Koren, G.5
  • 51
    • 84859739898 scopus 로고    scopus 로고
    • Neonatal screening for prenatal alcohol exposure: assessment of voluntary maternal participation in an open meconium screening program
    • Zelner I, Shor S, Lynn H, Roukema H, Lum L, Eisinga K, Koren G (2012b) Neonatal screening for prenatal alcohol exposure: assessment of voluntary maternal participation in an open meconium screening program. Alcohol 46:269-276.
    • (2012) Alcohol , vol.46 , pp. 269-276
    • Zelner, I.1    Shor, S.2    Lynn, H.3    Roukema, H.4    Lum, L.5    Eisinga, K.6    Koren, G.7


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