Homology modeling, molecular dynamics and inhibitor binding study on MurD ligase of Mycobacterium tuberculosis

Interdisciplinary Sciences – Computational Life Sciences

Volumn 4, Issue 3, 2012, Pages 223-238

  Arvind, Akanksha ^a,d   Kumar, Vivek ^a   Saravanan, Parameswaran ^b   Mohan, C Gopi ^c  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY GUWAHATI   (India)

^c AMRITA INSTITUTE OF MEDICAL SCIENCES   (India)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

chemotherapy; homology modeling; molecular docking; molecular dynamics; Mtb MurD; peptidoglycan; protein structure; resistance

Indexed keywords

ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

GLUTAMIC ACID; PEPTIDE SYNTHASE; UDP N ACETYLMURAMOYLALANINE D GLUTAMATE LIGASE; UDP-N-ACETYLMURAMOYLALANINE-D-GLUTAMATE LIGASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR GENETICS; MYCOBACTERIUM TUBERCULOSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; GLUTAMIC ACID; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PEPTIDE SYNTHASES; SEQUENCE HOMOLOGY, AMINO ACID;

MLCS; MLOWN;

EID: 84878348793     PISSN: 19132751     EISSN: 18671462     Source Type: Journal    
DOI: 10.1007/s12539-012-0133-x     Document Type: Article

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