-
1
-
-
84867880208
-
SIRT1 in metabolic syndrome: Where to target matters
-
Wang Y, Xu C, Liang Y and Vanhoutte PM. SIRT1 in metabolic syndrome: where to target matters. Pharmacol Ther 2012; 136: 305-318.
-
(2012)
Pharmacol Ther
, vol.136
, pp. 305-318
-
-
Wang, Y.1
Xu, C.2
Liang, Y.3
Vanhoutte, P.M.4
-
2
-
-
84859977895
-
Sirtuins mediate mammalian metabolic responses to nutrient availability
-
Chalkiadaki A and Guarente L. Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat Rev Endocrinol 2012; 8: 287-296.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 287-296
-
-
Chalkiadaki, A.1
Guarente, L.2
-
4
-
-
14844317297
-
Molecular links between aging and adipose tissue
-
Picard F and Guarente L. Molecular links between aging and adipose tissue. Int J Obes (Lond) 2005; 29 Suppl 1: S36-39.
-
(2005)
Int J Obes (Lond)
, vol.29
, Issue.SUPPL. 1
-
-
Picard, F.1
Guarente, L.2
-
5
-
-
33244486764
-
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
-
Bordone L, Motta MC, Picard F, Robinson A, Jhala US, Apfeld J, McDonagh T, Lemieux M, McBurney M, Szilvasi A, Easlon EJ, Lin SJ and Guarente L. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells. PLoS Biol 2006; 4: e31.
-
(2006)
PLoS Biol
, vol.4
-
-
Bordone, L.1
Motta, M.C.2
Picard, F.3
Robinson, A.4
Jhala, U.S.5
Apfeld, J.6
McDonagh, T.7
Lemieux, M.8
McBurney, M.9
Szilvasi, A.10
Easlon, E.J.11
Lin, S.J.12
Guarente, L.13
-
7
-
-
84858750516
-
Metabolic actions of hypothalamic SIRT1
-
Coppari R. Metabolic actions of hypothalamic SIRT1. Trends Endocrinol Metab 2012; 23: 179-185.
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 179-185
-
-
Coppari, R.1
-
8
-
-
84861852370
-
Are sirtuins viable targets for improving healthspan and lifespan?
-
Baur JA, Ungvari Z, Minor RK, Le Couteur DG and de Cabo R. Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov 2012; 11: 443-461.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 443-461
-
-
Baur, J.A.1
Ungvari, Z.2
Minor, R.K.3
Le Couteur, D.G.4
de Cabo, R.5
-
9
-
-
84859909860
-
SRT1720 improves survival and healthspan of obese mice
-
Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martin-Montalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA and de Cabo R. SRT1720 improves survival and healthspan of obese mice. Sci Rep 2012; 1: 70.
-
(2012)
Sci Rep
, vol.1
, pp. 70
-
-
Minor, R.K.1
Baur, J.A.2
Gomes, A.P.3
Ward, T.M.4
Csiszar, A.5
Mercken, E.M.6
Abdelmohsen, K.7
Shin, Y.K.8
Canto, C.9
Scheibye-Knudsen, M.10
Krawczyk, M.11
Irusta, P.M.12
Martin-Montalvo, A.13
Hubbard, B.P.14
Zhang, Y.15
Lehrmann, E.16
White, A.A.17
Price, N.L.18
Swindell, W.R.19
Pearson, K.J.20
Becker, K.G.21
Bohr, V.A.22
Gorospe, M.23
Egan, J.M.24
Talan, M.I.25
Auwerx, J.26
Westphal, C.H.27
Ellis, J.L.28
Ungvari, Z.29
Vlasuk, G.P.30
Elliott, P.J.31
Sinclair, D.A.32
de Cabo, R.33
more..
-
10
-
-
82255164629
-
SirT1 regulates adipose tissue inflammation
-
Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S and Shulman GI. SirT1 regulates adipose tissue inflammation. Diabetes 2011; 60: 3235-3245.
-
(2011)
Diabetes
, vol.60
, pp. 3235-3245
-
-
Gillum, M.P.1
Kotas, M.E.2
Erion, D.M.3
Kursawe, R.4
Chatterjee, P.5
Nead, K.T.6
Muise, E.S.7
Hsiao, J.J.8
Frederick, D.W.9
Yonemitsu, S.10
Banks, A.S.11
Qiang, L.12
Bhanot, S.13
Olefsky, J.M.14
Sears, D.D.15
Caprio, S.16
Shulman, G.I.17
-
11
-
-
82255183479
-
SirT1: A guardian at the gates of adipose tissue inflammation
-
Cho KW and Lumeng CN. SirT1: a guardian at the gates of adipose tissue inflammation. Diabetes 2011; 60: 3100-3102.
-
(2011)
Diabetes
, vol.60
, pp. 3100-3102
-
-
Cho, K.W.1
Lumeng, C.N.2
-
12
-
-
52749091816
-
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
-
Banks AS, Kon N, Knight C, Matsumoto M, Gutierrez-Juarez R, Rossetti L, Gu W and Accili D. SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 2008; 8: 333-341.
-
(2008)
Cell Metab
, vol.8
, pp. 333-341
-
-
Banks, A.S.1
Kon, N.2
Knight, C.3
Matsumoto, M.4
Gutierrez-Juarez, R.5
Rossetti, L.6
Gu, W.7
Accili, D.8
-
13
-
-
84859400813
-
Angiogenic Deficiency and Adipose Tissue Dysfunction Are Associated with Macrophage Malfunction in SIRT1-/-Mice
-
Xu F, Burk D, Gao Z, Yin J, Zhang X, Weng J and Ye J. Angiogenic Deficiency and Adipose Tissue Dysfunction Are Associated with Macrophage Malfunction in SIRT1-/-Mice. Endocrinology 2012; 153: 1706-1716.
-
(2012)
Endocrinology
, vol.153
, pp. 1706-1716
-
-
Xu, F.1
Burk, D.2
Gao, Z.3
Yin, J.4
Zhang, X.5
Weng, J.6
Ye, J.7
-
14
-
-
84864678390
-
High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction
-
Chalkiadaki A and Guarente L. High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction. Cell Metab 2012; 16: 180-188.
-
(2012)
Cell Metab
, vol.16
, pp. 180-188
-
-
Chalkiadaki, A.1
Guarente, L.2
-
15
-
-
84866706026
-
Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue
-
Pettersson US, Walden TB, Carlsson PO, Jansson L and Phillipson M. Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue. PLoS One 2012; 7: e46057.
-
(2012)
PLoS One
, vol.7
-
-
Pettersson, U.S.1
Walden, T.B.2
Carlsson, P.O.3
Jansson, L.4
Phillipson, M.5
-
16
-
-
79955908536
-
A non-specific effect associated with conditional transgene expression based on Cre-loxP strategy in mice
-
Qiu L, Rivera-Perez JA and Xu Z. A non-specific effect associated with conditional transgene expression based on Cre-loxP strategy in mice. PLoS One 2011; 6: e18778.
-
(2011)
PLoS One
, vol.6
-
-
Qiu, L.1
Rivera-Perez, J.A.2
Xu, Z.3
-
17
-
-
84864615516
-
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Ppargamma
-
Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, Rosenbaum M, Zhao Y, Gu W, Farmer SR and Accili D. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Ppargamma. Cell 2012; 150: 620-632.
-
(2012)
Cell
, vol.150
, pp. 620-632
-
-
Qiang, L.1
Wang, L.2
Kon, N.3
Zhao, W.4
Lee, S.5
Zhang, Y.6
Rosenbaum, M.7
Zhao, Y.8
Gu, W.9
Farmer, S.R.10
Accili, D.11
-
18
-
-
79551600855
-
Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice
-
Zhang X, Xu A, Chung SK, Cresser JH, Sweeney G, Wong RL, Lin A and Lam KS. Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice. Diabetes 2011; 60: 486-495.
-
(2011)
Diabetes
, vol.60
, pp. 486-495
-
-
Zhang, X.1
Xu, A.2
Chung, S.K.3
Cresser, J.H.4
Sweeney, G.5
Wong, R.L.6
Lin, A.7
Lam, K.S.8
-
19
-
-
84871889884
-
Fatty acid binding protein 4 expression marks a population of adipocyte progenitors in white and brown adipose tissues
-
Shan T, Liu W and Kuang S. Fatty acid binding protein 4 expression marks a population of adipocyte progenitors in white and brown adipose tissues. FASEB J 2013; 27: 277-287.
-
(2013)
FASEB J
, vol.27
, pp. 277-287
-
-
Shan, T.1
Liu, W.2
Kuang, S.3
-
20
-
-
38949125405
-
Post-translational modifications of adiponectin: Mechanisms and functional implications
-
Wang Y, Lam KS, Yau MH and Xu A. Post-translational modifications of adiponectin: mechanisms and functional implications. Biochem J 2008; 409: 623-633.
-
(2008)
Biochem J
, vol.409
, pp. 623-633
-
-
Wang, Y.1
Lam, K.S.2
Yau, M.H.3
Xu, A.4
-
21
-
-
8844226709
-
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
-
Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A and Zechner R. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 2004; 306: 1383-1386.
-
(2004)
Science
, vol.306
, pp. 1383-1386
-
-
Zimmermann, R.1
Strauss, J.G.2
Haemmerle, G.3
Schoiswohl, G.4
Birner-Gruenberger, R.5
Riederer, M.6
Lass, A.7
Neuberger, G.8
Eisenhaber, F.9
Hermetter, A.10
Zechner, R.11
-
22
-
-
66249144685
-
Identification and characterization of proteins interacting with SIRT1 and SIRT3: Implications in the antiaging and metabolic effects of sirtuins
-
Law IK, Liu L, Xu A, Lam KS, Vanhoutte PM, Che CM, Leung PT and Wang Y. Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the antiaging and metabolic effects of sirtuins. Proteomics 2009; 9: 2444-2456.
-
(2009)
Proteomics
, vol.9
, pp. 2444-2456
-
-
Law, I.K.1
Liu, L.2
Xu, A.3
Lam, K.S.4
Vanhoutte, P.M.5
Che, C.M.6
Leung, P.T.7
Wang, Y.8
-
23
-
-
33751579134
-
Acetyl-coenzyme A carboxylases: Versatile targets for drug discovery
-
Tong L and Harwood HJ Jr. Acetyl-coenzyme A carboxylases: versatile targets for drug discovery. J Cell Biochem 2006; 99: 1476-1488.
-
(2006)
J Cell Biochem
, vol.99
, pp. 1476-1488
-
-
Tong, L.1
Harwood Jr., H.J.2
-
24
-
-
0027156473
-
Depletion and repletion of biotinyl enzymes in liver of biotin-deficient rats: Evidence of a biotin storage system
-
Shriver BJ, Roman-Shriver C and Allred JB. Depletion and repletion of biotinyl enzymes in liver of biotin-deficient rats: evidence of a biotin storage system. J Nutr 1993; 123: 1140-1149.
-
(1993)
J Nutr
, vol.123
, pp. 1140-1149
-
-
Shriver, B.J.1
Roman-Shriver, C.2
Allred, J.B.3
-
26
-
-
0025836220
-
Transcriptional regulation of the glucokinase gene by biotin in starved rats
-
Chauhan J and Dakshinamurti K. Transcriptional regulation of the glucokinase gene by biotin in starved rats. J Biol Chem 1991; 266: 10035-10038.
-
(1991)
J Biol Chem
, vol.266
, pp. 10035-10038
-
-
Chauhan, J.1
Dakshinamurti, K.2
-
27
-
-
0023839754
-
Effects of biotin deficiency on serum fatty acid composition: Evidence for abnormalities in humans
-
Mock DM, Johnson SB and Holman RT. Effects of biotin deficiency on serum fatty acid composition: evidence for abnormalities in humans. J Nutr 1988; 118: 342-348.
-
(1988)
J Nutr
, vol.118
, pp. 342-348
-
-
Mock, D.M.1
Johnson, S.B.2
Holman, R.T.3
-
28
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
-
Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M and Sinclair DA. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 2002; 277: 45099-45107.
-
(2002)
J Biol Chem
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
29
-
-
0034687694
-
Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
-
Tanner KG, Landry J, Sternglanz R and Denu JM. Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc Natl Acad Sci U S A 2000; 97: 14178-14182.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14178-14182
-
-
Tanner, K.G.1
Landry, J.2
Sternglanz, R.3
Denu, J.M.4
-
30
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M and Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000; 403: 795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
31
-
-
50849135494
-
Structural insights into intermediate steps in the Sir2 deacetylation reaction
-
Hawse WF, Hoff KG, Fatkins DG, Daines A, Zubkova OV, Schramm VL, Zheng W and Wolberger C. Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure 2008; 16: 1368-1377.
-
(2008)
Structure
, vol.16
, pp. 1368-1377
-
-
Hawse, W.F.1
Hoff, K.G.2
Fatkins, D.G.3
Daines, A.4
Zubkova, O.V.5
Schramm, V.L.6
Zheng, W.7
Wolberger, C.8
-
32
-
-
0035917536
-
Crystal structure of a SIR2 homolog-NAD complex
-
Min J, Landry J, Sternglanz R and Xu RM. Crystal structure of a SIR2 homolog-NAD complex. Cell 2001; 105: 269-279.
-
(2001)
Cell
, vol.105
, pp. 269-279
-
-
Min, J.1
Landry, J.2
Sternglanz, R.3
Xu, R.M.4
-
33
-
-
2942534101
-
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases
-
Zhao K, Harshaw R, Chai X and Marmorstein R. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc Natl Acad Sci U S A 2004; 101: 8563-8568.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8563-8568
-
-
Zhao, K.1
Harshaw, R.2
Chai, X.3
Marmorstein, R.4
-
34
-
-
15244355745
-
Mechanism of sirtuin inhibition by nicotinamide: Altering the NAD(+) cosubstrate specificity of a Sir2 enzyme
-
Avalos JL, Bever KM and Wolberger C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol Cell 2005; 17: 855-868.
-
(2005)
Mol Cell
, vol.17
, pp. 855-868
-
-
Avalos, J.L.1
Bever, K.M.2
Wolberger, C.3
-
35
-
-
33745534953
-
Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acety lated peptide
-
Hoff KG, Avalos JL, Sens K and Wolberger C. Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acety lated peptide. Structure 2006; 14: 1231-1240.
-
(2006)
Structure
, vol.14
, pp. 1231-1240
-
-
Hoff, K.G.1
Avalos, J.L.2
Sens, K.3
Wolberger, C.4
-
36
-
-
78349299099
-
Fat tissue, aging, and cellular senescence
-
Tchkonia T, Morbeck DE, Von Zglinicki T, Van Deursen J, Lustgarten J, Scrable H, Khosla S, Jensen MD and Kirkland JL. Fat tissue, aging, and cellular senescence. Aging Cell 2010; 9: 667-684.
-
(2010)
Aging Cell
, vol.9
, pp. 667-684
-
-
Tchkonia, T.1
Morbeck, D.E.2
von Zglinicki, T.3
van Deursen, J.4
Lustgarten, J.5
Scrable, H.6
Khosla, S.7
Jensen, M.D.8
Kirkland, J.L.9
-
37
-
-
0036073319
-
Longitudinal changes in body composition in older men and women: Role of body weight change and physical activity
-
Hughes VA, Frontera WR, Roubenoff R, Evans WJ and Singh MA. Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr 2002; 76: 473-481.
-
(2002)
Am J Clin Nutr
, vol.76
, pp. 473-481
-
-
Hughes, V.A.1
Frontera, W.R.2
Roubenoff, R.3
Evans, W.J.4
Singh, M.A.5
-
38
-
-
84876175611
-
How lifespan associated genes modulate aging changes: Lessons from analysis of longitudinal data
-
Yashin AI, Arbeev KG, Wu D, Arbeeva LS, Kulminski A, Akushevich I, Culminskaya I, Stallard E and Ukraintseva SV. How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data. Front Genet 2013; 4: 3.
-
(2013)
Front Genet
, vol.4
, pp. 3
-
-
Yashin, A.I.1
Arbeev, K.G.2
Wu, D.3
Arbeeva, L.S.4
Kulminski, A.5
Akushevich, I.6
Culminskaya, I.7
Stallard, E.8
Ukraintseva, S.V.9
-
39
-
-
69949187615
-
Connecting obesity, aging and diabetes
-
Ahima RS. Connecting obesity, aging and diabetes. Nat Med 2009; 15: 996-997.
-
(2009)
Nat Med
, vol.15
, pp. 996-997
-
-
Ahima, R.S.1
-
40
-
-
70350434300
-
aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues
-
Mao J, Yang T, Gu Z, Heird WC, Finegold MJ, Lee B and Wakil SJ. aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues. Proc Natl Acad Sci U S A 2009; 106: 17576-17581.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17576-17581
-
-
Mao, J.1
Yang, T.2
Gu, Z.3
Heird, W.C.4
Finegold, M.J.5
Lee, B.6
Wakil, S.J.7
-
41
-
-
0033199782
-
The enzymatic biotinylation of proteins: A post-translational modification of exceptional specificity
-
Chapman-Smith A and Cronan JE Jr. The enzymatic biotinylation of proteins: a post-translational modification of exceptional specificity. Trends Biochem Sci 1999; 24: 359-363.
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 359-363
-
-
Chapman-Smith, A.1
Cronan Jr., J.E.2
-
42
-
-
0019787158
-
Biotin in clinical medicine--a review
-
Roth KS. Biotin in clinical medicine--a review. Am J Clin Nutr 1981; 34: 1967-1974.
-
(1981)
Am J Clin Nutr
, vol.34
, pp. 1967-1974
-
-
Roth, K.S.1
-
43
-
-
21344463799
-
Pharmacological effects of biotin
-
Fernandez-Mejia C. Pharmacological effects of biotin. J Nutr Biochem 2005; 16: 424-427.
-
(2005)
J Nutr Biochem
, vol.16
, pp. 424-427
-
-
Fernandez-Mejia, C.1
-
44
-
-
77950620338
-
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
-
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FP, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R and Zimmermann R. Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids. J Lipid Res 2010; 51: 490-499.
-
(2010)
J Lipid Res
, vol.51
, pp. 490-499
-
-
Schoiswohl, G.1
Schweiger, M.2
Schreiber, R.3
Gorkiewicz, G.4
Preiss-Landl, K.5
Taschler, U.6
Zierler, K.A.7
Radner, F.P.8
Eichmann, T.O.9
Kienesberger, P.C.10
Eder, S.11
Lass, A.12
Haemmerle, G.13
Alsted, T.J.14
Kiens, B.15
Hoefler, G.16
Zechner, R.17
Zimmermann, R.18
-
45
-
-
63449127032
-
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores
-
Zechner R, Kienesberger PC, Haemmerle G, Zimmermann R and Lass A. Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. J Lipid Res 2009; 50: 3-21.
-
(2009)
J Lipid Res
, vol.50
, pp. 3-21
-
-
Zechner, R.1
Kienesberger, P.C.2
Haemmerle, G.3
Zimmermann, R.4
Lass, A.5
-
46
-
-
80051826470
-
SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL
-
Chakrabarti P, English T, Karki S, Qiang L, Tao R, Kim J, Luo Z, Farmer SR and Kandror KV. SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL. J Lipid Res 2011; 52: 1693-1701.
-
(2011)
J Lipid Res
, vol.52
, pp. 1693-1701
-
-
Chakrabarti, P.1
English, T.2
Karki, S.3
Qiang, L.4
Tao, R.5
Kim, J.6
Luo, Z.7
Farmer, S.R.8
Kandror, K.V.9
-
47
-
-
84869083957
-
K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells
-
Rios-Avila L, Pestinger V and Zempleni J. K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells. J Nutr Biochem 2012; 23: 1559-1564.
-
(2012)
J Nutr Biochem
, vol.23
, pp. 1559-1564
-
-
Rios-Avila, L.1
Pestinger, V.2
Zempleni, J.3
-
48
-
-
59949084113
-
Nonenzymatic biotinylation of histone H2A
-
Healy S, Heightman TD, Hohmann L, Schriemer D and Gravel RA. Nonenzymatic biotinylation of histone H2A. Protein Sci 2009; 18: 314-328.
-
(2009)
Protein Sci
, vol.18
, pp. 314-328
-
-
Healy, S.1
Heightman, T.D.2
Hohmann, L.3
Schriemer, D.4
Gravel, R.A.5
-
49
-
-
82255174922
-
Biotinylation is a natural, albeit rare, modification of human histones
-
Kuroishi T, Rios-Avila L, Pestinger V, Wijeratne SS and Zempleni J. Biotinylation is a natural, albeit rare, modification of human histones. Mol Genet Metab 2011; 104: 537-545.
-
(2011)
Mol Genet Metab
, vol.104
, pp. 537-545
-
-
Kuroishi, T.1
Rios-Avila, L.2
Pestinger, V.3
Wijeratne, S.S.4
Zempleni, J.5
-
50
-
-
59349092364
-
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats
-
Fukuwatari T, Wada H and Shibata K. Age-related alterations of B-group vitamin contents in urine, blood and liver from rats. J Nutr Sci Vitaminol (Tokyo) 2008; 54: 357-362.
-
(2008)
J Nutr Sci Vitaminol (Tokyo)
, vol.54
, pp. 357-362
-
-
Fukuwatari, T.1
Wada, H.2
Shibata, K.3
-
51
-
-
0025189770
-
Effect of aging on intestinal biotin transport in the rat
-
Said HM, Horne DW and Mock DM. Effect of aging on intestinal biotin transport in the rat. Exp Gerontol 1990; 25: 67-73.
-
(1990)
Exp Gerontol
, vol.25
, pp. 67-73
-
-
Said, H.M.1
Horne, D.W.2
Mock, D.M.3
-
52
-
-
79953712005
-
Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast
-
Pluskal T, Hayashi T, Saitoh S, Fujisawa A and Yanagida M. Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast. FEBS J 2011; 278: 1299-1315.
-
(2011)
FEBS J
, vol.278
, pp. 1299-1315
-
-
Pluskal, T.1
Hayashi, T.2
Saitoh, S.3
Fujisawa, A.4
Yanagida, M.5
-
53
-
-
7944234368
-
Biotin deficiency decreases life span and fertility but increases stress resistance in Drosophila melanogaster
-
Landenberger A, Kabil H, Harshman LG and Zempleni J. Biotin deficiency decreases life span and fertility but increases stress resistance in Drosophila melanogaster. J Nutr Biochem 2004; 15: 591-600.
-
(2004)
J Nutr Biochem
, vol.15
, pp. 591-600
-
-
Landenberger, A.1
Kabil, H.2
Harshman, L.G.3
Zempleni, J.4
-
54
-
-
34548410575
-
Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patterns
-
Smith EM, Hoi JT, Eissenberg JC, Shoemaker JD, Neckameyer WS, Ilvarsonn AM, Harshman LG, Schlegel VL and Zempleni J. Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patterns. J Nutr 2007; 137: 2006-2012.
-
(2007)
J Nutr
, vol.137
, pp. 2006-2012
-
-
Smith, E.M.1
Hoi, J.T.2
Eissenberg, J.C.3
Shoemaker, J.D.4
Neckameyer, W.S.5
Ilvarsonn, A.M.6
Harshman, L.G.7
Schlegel, V.L.8
Zempleni, J.9
-
55
-
-
77958508121
-
Adipose tissue-specific inhibition of hypoxia inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice
-
Zhang X, Lam KS, Ye H, Chung SK, Zhou M, Wang Y and Xu A. Adipose tissue-specific inhibition of hypoxia inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice. J Biol Chem 2010; 285: 32869-32877.
-
(2010)
J Biol Chem
, vol.285
, pp. 32869-32877
-
-
Zhang, X.1
Lam, K.S.2
Ye, H.3
Chung, S.K.4
Zhou, M.5
Wang, Y.6
Xu, A.7
-
56
-
-
0025637601
-
A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo
-
Ross SR, Graves RA, Greenstein A, Platt KA, Shyu HL, Mellovitz B and Spiegelman BM. A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo. Proc Natl Acad Sci U S A 1990; 87: 9590-9594.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 9590-9594
-
-
Ross, S.R.1
Graves, R.A.2
Greenstein, A.3
Platt, K.A.4
Shyu, H.L.5
Mellovitz, B.6
Spiegelman, B.M.7
-
57
-
-
77951193688
-
Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity
-
Law IK, Xu A, Lam KS, Berger T, Mak TW, Vanhoutte PM, Liu JT, Sweeney G, Zhou M, Yang B and Wang Y. Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity. Diabetes 2010; 59: 872-882.
-
(2010)
Diabetes
, vol.59
, pp. 872-882
-
-
Law, I.K.1
Xu, A.2
Lam, K.S.3
Berger, T.4
Mak, T.W.5
Vanhoutte, P.M.6
Liu, J.T.7
Sweeney, G.8
Zhou, M.9
Yang, B.10
Wang, Y.11
-
58
-
-
77951193688
-
Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity
-
Law IK, Xu A, Lam KS, Berger T, Mak TW, Vanhoutte PM, Liu JT, Sweeney G, Zhou M, Yang B and Wang Y. Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity. Diabetes 2010; 59: 872-882.
-
(2010)
Diabetes
, vol.59
, pp. 872-882
-
-
Law, I.K.1
Xu, A.2
Lam, K.S.3
Berger, T.4
Mak, T.W.5
Vanhoutte, P.M.6
Liu, J.T.7
Sweeney, G.8
Zhou, M.9
Yang, B.10
Wang, Y.11
-
59
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV, Jr., Alt FW, Kahn CR and Verdin E. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 2010; 464: 121-125.
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
Stevens, R.D.11
Li, Y.12
Saha, A.K.13
Ruderman, N.B.14
Bain, J.R.15
Newgard, C.B.16
Farese Jr., R.V.17
Alt, F.W.18
Kahn, C.R.19
Verdin, E.20
more..
-
60
-
-
54449085766
-
Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury
-
Zhou M, Xu A, Tam PK, Lam KS, Chan L, Hoo RL, Liu J, Chow KH and Wang Y. Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury. Hepatology 2008; 48: 1087-1096.
-
(2008)
Hepatology
, vol.48
, pp. 1087-1096
-
-
Zhou, M.1
Xu, A.2
Tam, P.K.3
Lam, K.S.4
Chan, L.5
Hoo, R.L.6
Liu, J.7
Chow, K.H.8
Wang, Y.9
-
61
-
-
0011057557
-
Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase
-
Witters LA, Watts TD, Daniels DL and Evans JL. Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase. Proc Natl Acad Sci U S A 1988; 85: 5473-5477.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 5473-5477
-
-
Witters, L.A.1
Watts, T.D.2
Daniels, D.L.3
Evans, J.L.4
-
62
-
-
75149132744
-
A gold(III) porphyrin complex with antitumor properties targets the Wnt/betacatenin pathway
-
Chow KH, Sun RW, Lam JB, Li CK, Xu A, Ma DL, Abagyan R, Wang Y and Che CM. A gold(III) porphyrin complex with antitumor properties targets the Wnt/betacatenin pathway. Cancer Res 2010; 70: 329-337.
-
(2010)
Cancer Res
, vol.70
, pp. 329-337
-
-
Chow, K.H.1
Sun, R.W.2
Lam, J.B.3
Li, C.K.4
Xu, A.5
Ma, D.L.6
Abagyan, R.7
Wang, Y.8
Che, C.M.9
|