Reversible regulation of aptamer activity with effector-responsive hairpin oligonucleotides

Journal of Laboratory Automation

Volumn 18, Issue 1, 2013, Pages 77-84

  Li, Na ^a  

^a University of Miami College of Engineering   (United States)

Author keywords

Antidotes; Aptamers; Hairpin oligonucleotides; Nucleic acid effectors; Reversible anticoagulant

Indexed keywords

NUCLEIC ACIDS;

ANTIDOTES; APTAMERS; CONFORMATIONAL CHANGE; GENERIC STRATEGIES; REVERSIBLE ANTICOAGULANT; SPECIFIC RECOGNITION; THERAPEUTIC ACTIVITY; THERAPEUTIC TARGETS;

OLIGONUCLEOTIDES;

APTAMER; FIBRINOGEN; HAIRPIN OLIGONUCLEOTIDE E1 C; HAIRPIN OLIGONUCLEOTIDE E2 C; HAIRPIN OLIGONUCLEOTIDE HP1; HAIRPIN OLIGONUCLEOTIDE HP2; NUCLEIC ACIDS EFFECTOR E1; NUCLEIC ACIDS, NUCLEIC ACID COMPONENTS AND THEIR DERIVATIVES; OLIGONUCLEOTIDE; THROMBIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CHEMICAL PARAMETERS; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG DESIGN; DRUG INHIBITION; DRUG PROTEIN BINDING; DRUG STRUCTURE; FEASIBILITY STUDY; GEL MOBILITY SHIFT ASSAY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PROTEIN CLEAVAGE; SPECIFICITY AND REVERSIBILITY; STRUCTURE ACTIVITY RELATION;

EID: 84878299398     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068212448429     Document Type: Article

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