Macromolecular chromogenic substrates for measuring proteinase activity

Clinical Chemistry

Volumn 47, Issue 2, 2001, Pages 215-222

  Hortin, G L ^a   Warshawsky, I ^a   Laude Sharp, M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 MACROGLOBULIN; BLOOD CLOTTING FACTOR; CHROMOGENIC SUBSTRATE; CHYMOTRYPSIN; PROTEINASE; THROMBIN; TRYPSIN;

ARTICLE; CATTLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE COMPLEX; HYDRODYNAMICS; MACROMOLECULE; NONHUMAN;

EID: 0035137916     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/47.2.215     Document Type: Article

References (33)

1. Über das Verhalten einiger Polypeptide gegen Pankreassaft [The behavior of some polypeptides toward pancreatic juice]
2. A classification of proteolytic enzymes
3. The specific esterase activity of trypsin
4. The action of thrombin on synthetic substrates
5. The preparation and properties of two new chromogenic substrates of trypsin
6. Aminosäure-p-nitroanilide als Substrate für Aminopeptidasen und andere p roteolytische Fermente
7. Synthetic chromogenic substrates for determination of trypsin, thrombin, and thrombin-like enzymes
8. On the size of the active site in proteases. I. Papain
9. Comparison of α-chymotrypsin and subtilisin BPN': Size and specificity of the active site
10. The specificity and mechanism of pepsin action
11. Dependence of the kinetic parameters for elastase-catalyzed amide hydrolysis on the length of peptide substrates
12. The action of thrombin on p-nitroanilide substrates: Substrate specificity and examination of hydrolysis under different reaction conditions
13. Synthetic peptides and peptidomimetics as substrates and inhibitors of thrombin and other proteases in the blood coagulation system
14. Mapping of the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: Development of new sensitive substrates
15. Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates
16. Ultrasensitive fluorogenic substrates for serine proteases
17. 2-macroglobulin-enzyme complexes
18. 2-macroglobulin-protease complexes
19. 2-Macroglobulin
20. α-Macroglobulins: Structure, shape, and mechanism of proteinase complex formation
21. 2-macroglobulin emerge from three-dimensional reconstructions of Fab labeled native, half-transformed, and transformed molecules
22. 2-macroglobulin can interfere in protein C assays by cleaving amidolytic substrates
23. 2-macroglobulin in the continuous measurement of the thrombin potential: Implications for an endpoint determination of the optical density
24. The estimation of pepsin, trypsin, papain, and cathepsin with hemoglobin
25. Crystalline soybean trypsin inhibitor. II. General properties
26. Allosteric changes in thrombin's activity produced by peptides corresponding to segments of natural inhibitors and substrates
27. Solution composition dependent variation in extinction coefficients for p-nitroaniline
28. Use of high-performance size exclusion chromatography to measure protein molecular weight and hydrodynamic radius. An investigation of the properties of the TSK 3000 SW column
29. Hydrodynamic characterization of random coil polymers by size exclusion chromatography
30. Steric exclusion is the principal source of the preferential hydration of proteins in the presence of polyethylene glycols
31. The refined 1.9 Å crystal structure of human α-thrombin: Interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment
32. Introduction to biotechnical and biomedical applications of poly (ethylene glycol)