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Volumn 429, Issue 6990, 2004, Pages 423-429

An autonomous molecular computer for logical control of gene expression

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMATION; BIOCHEMISTRY; BIOSENSORS; COMPUTATIONAL COMPLEXITY; COMPUTER SOFTWARE; DRUG PRODUCTS; GENES; MOLECULAR DYNAMICS; RNA; TUMORS;

EID: 2642555548     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02551     Document Type: Article
Times cited : (724)

References (30)
  • 1
    • 0028114541 scopus 로고
    • Molecular computation of solutions to combinatorial problems
    • Adelman, L. M. Molecular computation of solutions to combinatorial problems. Science 266, 1021-1024 (1994).
    • (1994) Science , vol.266 , pp. 1021-1024
    • Adelman, L.M.1
  • 2
    • 0029278612 scopus 로고
    • DNA solution of hard computational problem
    • Lipton, R. J. DNA solution of hard computational problem. Science 268, 542-545 (1995).
    • (1995) Science , vol.268 , pp. 542-545
    • Lipton, R.J.1
  • 3
    • 0030725521 scopus 로고    scopus 로고
    • DNA solution of the maximal clique problem
    • Ouyang, Q., Kaplan, P. D., Liu, S. & Libchaber, A. DNA solution of the maximal clique problem. Science 278, 446-449 (1997).
    • (1997) Science , vol.278 , pp. 446-449
    • Ouyang, Q.1    Kaplan, P.D.2    Liu, S.3    Libchaber, A.4
  • 4
    • 0032705470 scopus 로고    scopus 로고
    • Design and implementation of computational systems based on programmed mutagenesis
    • Khodor, J. & Gifford, D. K. Design and implementation of computational systems based on programmed mutagenesis. Biosystems 52, 93-97 (1999).
    • (1999) Biosystems , vol.52 , pp. 93-97
    • Khodor, J.1    Gifford, D.K.2
  • 6
    • 0034642536 scopus 로고    scopus 로고
    • DNA computing on surfaces
    • Liu, Q. et al. DNA computing on surfaces. Nature 403, 175-179 (2000).
    • (2000) Nature , vol.403 , pp. 175-179
    • Liu, Q.1
  • 7
    • 0034305052 scopus 로고    scopus 로고
    • The past, present and future of molecular computing
    • Ruben, A. J. & Landweber, L. F. The past, present and future of molecular computing. Nature Rev. Mol. Cell Biol. 1, 69-72 (2000).
    • (2000) Nature Rev. Mol. Cell Biol. , vol.1 , pp. 69-72
    • Ruben, A.J.1    Landweber, L.F.2
  • 8
    • 0032490948 scopus 로고    scopus 로고
    • Design and self-assembly of two-dimensional DNA crystals
    • Winfree, E., Liu, F. R., Wenzler, L. A. & Seeman, N. C. Design and self-assembly of two-dimensional DNA crystals. Nature 394, 539-544 (1998).
    • (1998) Nature , vol.394 , pp. 539-544
    • Winfree, E.1    Liu, F.R.2    Wenzler, L.A.3    Seeman, N.C.4
  • 9
    • 0034727072 scopus 로고    scopus 로고
    • Logical computation using algorithmic self-assembly of DNA triple-crossover molecules
    • Mao, C., LaBean, T. H., Reif, J. H. & Seeman, N. C. Logical computation using algorithmic self-assembly of DNA triple-crossover molecules. Nature 407, 493-496 (2000).
    • (2000) Nature , vol.407 , pp. 493-496
    • Mao, C.1    LaBean, T.H.2    Reif, J.H.3    Seeman, N.C.4
  • 10
    • 0032747007 scopus 로고    scopus 로고
    • State transitions by molecules
    • Sakamoto, K. et al. State transitions by molecules. Biosystems 52, 81-91 (1999).
    • (1999) Biosystems , vol.52 , pp. 81-91
    • Sakamoto, K.1
  • 11
    • 0034685812 scopus 로고    scopus 로고
    • Molecular computation by DNA hairpin formation
    • Sakamoto, K. et al. Molecular computation by DNA hairpin formation. Science 288, 1223-1226 (2000).
    • (2000) Science , vol.288 , pp. 1223-1226
    • Sakamoto, K.1
  • 12
    • 0035936116 scopus 로고    scopus 로고
    • Programmable and autonomous computing machine made of biomolecules
    • Benenson, Y. et al. Programmable and autonomous computing machine made of biomolecules. Nature 414, 430-434 (2001).
    • (2001) Nature , vol.414 , pp. 430-434
    • Benenson, Y.1
  • 14
    • 24244451712 scopus 로고    scopus 로고
    • Stochastic computing with biomolecular automata
    • submitted
    • Adar, R. et al. Stochastic computing with biomolecular automata. Proc. Natl Acad. Sci. USA (submitted).
    • Proc. Natl. Acad. Sci. USA
    • Adar, R.1
  • 16
    • 50549176920 scopus 로고
    • Probabilistic automata
    • Rabin, M. O. Probabilistic automata. Inform. Contr. 6, 230-245 (1963).
    • (1963) Inform. Contr. , vol.6 , pp. 230-245
    • Rabin, M.O.1
  • 17
    • 0037015031 scopus 로고    scopus 로고
    • Protein-DNA computation by stochastic assembly cascade
    • Bar-Ziv, R., Tlusty, T. & Libchaber, A. Protein-DNA computation by stochastic assembly cascade. Proc. Natl Acad. Sci. USA 99, 11589-11592 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 11589-11592
    • Bar-Ziv, R.1    Tlusty, T.2    Libchaber, A.3
  • 18
    • 0036515416 scopus 로고    scopus 로고
    • Emerging molecular markers of cancer
    • Sidransky, D. Emerging molecular markers of cancer. Nature Rev. Cancer 2, 210-219 (2002).
    • (2002) Nature Rev. Cancer , vol.2 , pp. 210-219
    • Sidransky, D.1
  • 19
    • 0037447191 scopus 로고    scopus 로고
    • Transcriptional gene expression profiling of small cell lung cancer cells
    • Pedersen, N. et al. Transcriptional gene expression profiling of small cell lung cancer cells. Cancer Res. 63, 1943-1953 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 1943-1953
    • Pedersen, N.1
  • 20
    • 0035939903 scopus 로고    scopus 로고
    • Delineation of prognostic biomarkers in prostate cancer
    • Dhanasekaran, S. M. et al. Delineation of prognostic biomarkers in prostate cancer. Nature 412, 822-826 (2001).
    • (2001) Nature , vol.412 , pp. 822-826
    • Dhanasekaran, S.M.1
  • 21
    • 0026068396 scopus 로고
    • The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution patter
    • Takahashi, T. et al. The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution patter. Oncogene 6, 1775-1778 (1991).
    • (1991) Oncogene , vol.6 , pp. 1775-1778
    • Takahashi, T.1
  • 22
    • 0036428708 scopus 로고    scopus 로고
    • cDNA arrays: Gene expression profiles of Hodgkin's disease and anaplastic large cell lymphoma cell lines
    • Thorns, C., Gaiser, T., Lange, K., Metz, H. & Feller, A. C. cDNA arrays: Gene expression profiles of Hodgkin's disease and anaplastic large cell lymphoma cell lines. Pathol. Int. 52, 578-585 (2002).
    • (2002) Pathol. Int. , vol.52 , pp. 578-585
    • Thorns, C.1    Gaiser, T.2    Lange, K.3    Metz, H.4    Feller, A.C.5
  • 23
    • 37049252569 scopus 로고
    • Reasoning foundation of medical diagnosis
    • Ledley, R. S. & Lusted, L. B. Reasoning foundation of medical diagnosis. Science 130, 9-21 (1959).
    • (1959) Science , vol.130 , pp. 9-21
    • Ledley, R.S.1    Lusted, L.B.2
  • 24
    • 0034575795 scopus 로고    scopus 로고
    • Analysis of medical-decision making and the use of standards of care in oncology
    • Holzer, S., Fremgen, A. M., Hundahl, S. A. & Dudeck, J. Analysis of medical-decision making and the use of standards of care in oncology. J. Am. Med. Inf. Assoc. (Suppl. S) 364-368 (2000).
    • (2000) J. Am. Med. Inf. Assoc. , Issue.SUPPL. S , pp. 364-368
    • Holzer, S.1    Fremgen, A.M.2    Hundahl, S.A.3    Dudeck, J.4
  • 25
    • 0035865516 scopus 로고    scopus 로고
    • Apoptosis of tumoral and nontumoral lymphoid cells is induced by both mdm2 and p53 antisense oligodeoxynucleotides
    • Capoulade, C. et al. Apoptosis of tumoral and nontumoral lymphoid cells is induced by both mdm2 and p53 antisense oligodeoxynucleotides. Blood 97, 1043-1049 (2001).
    • (2001) Blood , vol.97 , pp. 1043-1049
    • Capoulade, C.1
  • 26
    • 1342332317 scopus 로고    scopus 로고
    • Applying antisense technology
    • Holmlund, J. T. Applying antisense technology. Ann. NY Acad. Sci. 1002, 244-251 (2003).
    • (2003) Ann. NY Acad. Sci. , vol.1002 , pp. 244-251
    • Holmlund, J.T.1
  • 29
    • 0042360338 scopus 로고    scopus 로고
    • A deoxyribozyme-based molecular automaton
    • Stojanovic, M. N. & Stefanovic, D. A deoxyribozyme-based molecular automaton. Nature Biotechnol. 21, 1069-1074 (2003).
    • (2003) Nature Biotechnol. , vol.21 , pp. 1069-1074
    • Stojanovic, M.N.1    Stefanovic, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.