Growth factors in the treatment of early osteoarthritis

Clinical Cases in Mineral and Bone Metabolism

Volumn 10, Issue 1, 2013, Pages 26-29

  Civinini, Roberto ^a   Nistri, Lorenzo ^a   Martini, Caterina ^a   Redl, Birgit ^a   Ristori, Gabriele ^a   Innocenti, Massimo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Early osteoarthritis; Growth factors; Platelet rich plasma

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH DIFFERENTIATION FACTOR 6; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ANGIOGENESIS; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMOTAXIS; COLLAGEN SYNTHESIS; EVIDENCE BASED MEDICINE; EXTRACELLULAR MATRIX; HUMAN; KNEE OSTEOARTHRITIS; NONHUMAN; OSTEOARTHRITIS; REVIEW; THROMBOCYTE RICH PLASMA;

EID: 84878294191     PISSN: 17248914     EISSN: 19713266     Source Type: Journal    
DOI: 10.11138/ccmbm/2013.10.1.026     Document Type: Review

References (37)

1. Chu CR, Williams AA, Coyle CH, et al. Early diagnosis to enable early treatment of pre-osteoarthritis. Arthritis research & therapy 2012 Jun;14(3):212.
2. Chung R, Foster BK, Xian CJ. Preclinical Studies on Mesenchymal Stem Cell-Based Therapy for Growth Plate Cartilage Injury Repair. Stem Cells Int 2011;2011:570125.
3. Civinini R, Macera A, Nistri L, et al. The use of autologous blood-derived growth factors in bone regeneration Clin Cases Miner Bone Metab 2011 Jan-Apr;8(1): 25-31.
4. Bucholz RW, Einhorn TA, Marsh JL. Bone and joint healing. In: Bucholz RW, Heckman JD, Court-Brown C; Sixth ed. Lippincott Williams & Wilkins; 2006. pp. 300-11.
5. Alves H, Munoz-Najar J, de Wit JR, et al. A link between the accumulation of DNA damage and loss of multipotency of human mesenchymal stromal cell. J Cell Mol Med 2010;14: 2729-2738.
6. Fortier LA, Barker JU, Strauss EJ, et al. The Role of Growth Factors in Cartilage Repair Clin Orthop Relat Res 2011 October;469(10): 2706-2715.
7. Kwon DR, Park GJ. Intra-Articular Injections for the Treatment of Osteoarthritis: Focus on the Clinical Use of Several Regimens. Osteoarthritis - Diagnosis, Treatment and Surgery 67-100.
8. Wu MY, Hill CS. TGF-beta superfamily signaling in embryonic development and homeostasis. Dev Cell 2009;16: 329-343.
9. Ellman MB, An HS, Muddasani P, et al., Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis. Gene 2008;420: 82-89.
10. Kurth T, Hedbom E, Shintani N, et al. Chondrogenic potential of human synovial mesenchymal stem cells in alginate. Osteoarthritis Cartilage 2007;15: 1178-1189.
11. Lee CH, Cook JL, Mendelson A, et al. Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet 2010;376: 440-448.
12. Lotz M, Rosen F, McCabe G, et al. Interleukin 1suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes. Proc Natl Acad Sci USA 1995 October;Vol. 92:pp. 10364-10368.
13. Fan J, Gong Y, Ren L, et al. In vitro engineered cartilage using synovium derived mesenchymal stem cells with injectable gellan hydrogels. Acta Biomater 2010;6: 1178-1185.
14. Kurth T, Hedbom E, Shintani N, et al. Chondrogenic potential of human synovial mesenchymal stem cells in alginate. Osteoarthritis Cartilage 2007;15: 1178-1189.
15. Diao H, Wang J, Shen C, et al. Improved cartilage regeneration utilizing mesenchymal stem cells in TGF-beta1 gene-activated scaffolds. Tissue Eng Part A 2009;15: 2687-2698.
16. Ellman MB, An HS, Muddasani P, et al. Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis. Gene 2008;420: 82-89.
17. Hoeben A, Landuyt B, Highley MS, et al. Vascular Endothelial Growth Factor and Angiogenesis. Pharmacological Reviews 2004 December;vol. 56, no. 4: 549-580.
18. Andrew JG, Hoyland JA, Freemont AJ, et al. Platelet-derived growth factor expression in normally healing human fractures. Bone 1995;16(4): 455-460.
19. Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg 2004;62: 498-93.
20. Tayapongsak P, O'Brien DA, Monteiro CB, et al. Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. J Oral Maxillofac Surg 1994;52: 161-5.
21. Wiltfang J, Kloss FR, Kessler P, et al. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in criticalsize defects. Clin Oral Implants Res 2004;15(2): 187-93.
22. Al Sukhun J, Helenius M, Lindqvist C, et al. Use of platelet rich plasma (PRP) in the reconstruction of mandibular bony defects: clinical and radiographic follow-up. Br J Oral Maxillofac Surg 2007 Jan 6.
23. Dugrillon A, Klüter H. Topical application of platelets for improved wound healing. Blood Ther Med 2002;3(1): 21-6.
24. Thor A, Franke-Stenport V, Johansson CB, et al. Early bone formation in human bone grafts treated with plateletrich plasma: Preliminary histomorphometric results. Int. J Oral Maxillofac Surg 2007;36: 1164-1171.
25. Ranly DM, Lohmann CH, Andreacchio D, et al. Platelet-rich plasma inhibits demineralized bone matrix-induced bone formation in nude mice. J Bone Joint Surg Am 2007;89(1): 139-47.
26. Gaissmaier C, Koh JL, Weise K. Growth and differentiation factors for cartilage healing and repair. Injury 2008;39:S88-S96.
27. Mishra A, Tummala P, King A, et al. Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation. Tissue Eng Part C Methods 2009 Sep;15(3): 431-5.
28. Sun Y, Feng Y, Zhang CQ, et al. The regenerative effect of platelet-rich plasma on healing in large osteochondral defects. Int Orthop 2010 Apr;34(4): 589-97.
29. Kwon DR, Park GY, Lee SU. The effects of intra-articular platelet-rich plasma injection according to the severity of collagenase-induced knee osteoarthritis in a rabbit model. Ann Rehabil Med 2012 Aug;36(4): 458-65.
30. Sanchez M, Anitua E, Azofra J, et al. Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: a retrospective cohort study. Clin Exp Rheumatol 2008 Sep-Oct;26(5): 910-3.
31. Kon E, Mandelbaum B, Buda R, et al. Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis. Arthroscopy 2011 Nov;27(11): 1490-501.
32. Sampson S, Reed M, Silvers H, et al. Injection of platelet-rich plasma in patients with primary and secondary knee osteoarthritis: a pilot study. Am J Phys Med Rehabil 2010 Dec;89(12): 961-9.
33. Wang-Saegusa A, Cugat R, Ares O, et al. Infltration of plasma rich in growth factors for osteoarthritis of the knee short-term effeects on function and quality of life. Arch Orthop Trauma Surg 2011;131: 311-317.
34. Filardo G, Kon E, Buda R, et al. Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis. Knee Surg Sports Traumatol Arthrosc 2011 Apr;19(4): 528-35.
35. Spakova T, Rosocha J, Lacko M, et al. Treatment of Knee Joint Osteoarthritis with Autologous Platelet-Rich Plasma in Comparison with Hyaluronic Acid. American Journal of Physical Medicine & Rehabilitation 2012 May; 91(5): 411-417.
36. Sanchez M., Guadilla J, Fiz N, et al. Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip. Rheumatology 2012;51: 144-150.
37. Milano G, Deriu L, Sanna Passino E, et al. Repeated platelet concentrate injections enhance reparative response of microfractures in the treatment of chondral defects of the knee: an experimental study in an animal model. Arthroscopy 2012 May;28(5): 688-701.