Early bone formation in human bone grafts treated with platelet-rich plasma: preliminary histomorphometric results

International Journal of Oral and Maxillofacial Surgery

Volumn 36, Issue 12, 2007, Pages 1164-1171

  Thor, A ^a,b   Franke Stenport, V ^b   Johansson, C B ^b,c   Rasmusson, L ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c ÖREBRO UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BONE BIOPSY; BONE GRAFT; CLINICAL ARTICLE; FEMALE; FRACTURE HEALING; HUMAN; MALE; MAXILLARY SINUS; MORPHOMETRICS; OSSIFICATION; THROMBOCYTE COUNT; THROMBOCYTE RICH PLASMA;

ADULT; AGED; BONE REGENERATION; BONE TRANSPLANTATION; FEMALE; HUMANS; ILIUM; MALE; MAXILLARY SINUS; MIDDLE AGED; PLATELET-RICH PLASMA; PROSTHESES AND IMPLANTS; STATISTICS, NONPARAMETRIC;

EID: 36248964731     PISSN: 09015027     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijom.2007.05.023     Document Type: Article

References (41)

1. Adell R., Lekholm U., Grondahl K., Branemark P.I., Lindstrom J., and Jacobsson M. Reconstruction of severely resorbed edentulous maxillae using osseointegrated fixtures in immediate autogenous bone grafts. Int J Oral Maxillofac Implants 5 (1990) 233-246
2. Aghaloo T.L., Moy P.K., and Freymiller E.G. Evaluation of platelet-rich plasma in combination with anorganic bovine bone in the rabbit cranium: a pilot study. Int J Oral Maxillofac Implants 19 (2004) 59-65
3. Aghaloo T.L., Moy P.K., and Freymiller E.G. Investigation of platelet-rich plasma in rabbit cranial defects: A pilot study. J Oral Maxillofac Surg 60 (2002) 1176-1181
4. Anitua E. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 14 (1999) 529-535
5. Anitua E., Andia I., Ardanza B., Nurden P., and Nurden A.T. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 91 (2004) 4-15
6. Blomqvist J.E., Alberius P., and Isaksson S. Two-stage maxillary sinus reconstruction with endosseous implants: a prospective study. Int J Oral Maxillofac Implants 13 (1998) 758-766
7. Boyne P.J., and James R.A. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg 38 (1980) 613-616
8. Breine U., and Branemark P.I. Reconstruction of alveolar jaw bone. An experimental and clinical study of immediate and preformed autologous bone grafts in combination with osseointegrated implants. Scand J Plast Reconstr Surg 14 (1980) 23-48
9. Choi B.H., Im C.J., Huh J.Y., Suh J.J., and Lee S.H. Effect of platelet-rich plasma on bone regeneration in autogenous bone graft. Int J Oral Maxillofac Surg 33 (2004) 56-59
10. Donath K. Die Trenn-Dünnschliff-Technik zur Herstellung histologischer Präparaten von nicht scneidbaren Geweben und Materialen. Der Präparator 34 (1988) 318-325
11. Donath K., and Breuner G. A method for the study of undecalcified bones and teeth with attached soft tissues. The Sage-Schliff (sawing and grinding) technique. J Oral Pathol 11 (1982) 318-326
12. Fennis J.P., Stoelinga P.J., and Jansen J.A. Mandibular reconstruction: a clinical and radiographic animal study on the use of autogenous scaffolds and platelet-rich plasma. Int J Oral Maxillofac Surg 31 (2002) 281-286
13. Fennis J.P., Stoelinga P.J., and Jansen J.A. Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats. Int J Oral Maxillofac Surg 33 (2004) 48-55
14. Gerard D., Carlson E.R., Gotcher J.E., and Jacobs M. Effects of platelet-rich plasma on the healing of autologous bone grafted mandibular defects in dogs. J Oral Maxillofac Surg 64 (2006) 443-451
15. Hock J.M., and Canalis E. Platelet-derived growth factor enhances bone cell replication, but not differentiated function of osteoblasts. Endocrinology 134 (1994) 1423-1428
16. Isaksson S. Evaluation of three bone grafting techniques for severely resorbed maxillae in conjunction with immediate endosseous implants. Int J Oral Maxillofac Implants 9 (1994) 679-688
17. Jakse N., Tangl S., Gilli R., Berghold A., Lorenzoni M., Eskici A., Haas R., and Pertl C. Influence of PRP on autogenous sinus grafts. An experimental study on sheep. Clin Oral Implants Res 14 (2003) 578-583
18. Jemt T., and Lekholm U. Measurements of buccal tissue volumes at single-implant restorations after local bone grafting in maxillas: a 3-year clinical prospective study case series. Clin Implant Dent Relat Res 5 (2003) 63-70
19. Johansson B., Grepe A., Wannfors K., and Hirsch J.M. A clinical study of changes in the volume of bone grafts in the atrophic maxilla. Dentomaxillofac Radiol 30 (2001) 157-161
20. Johansson B., Wannfors K., Ekenback J., Smedberg J.I., and Hirsch J. Implants and sinus-inlay bone grafts in a 1-stage procedure on severely atrophied maxillae: surgical aspects of a 3-year follow-up study. Int J Oral Maxillofac Implants 14 (1999) 811-818
21. Johansson C. On tissue reaction to metal implants (1991), Göteborg University, Göteborg
22. Johansson C.B., and Morberg P. Importance of ground section thickness for reliable histomorphometrical results. Biomaterials 16 (1995) 91-95
23. Keller E.E., Van Roekel N.B., Desjardins R.P., and Tolman D.E. Prosthetic-surgical reconstruction of the severely resorbed maxilla with iliac bone grafting and tissue-integrated prostheses. Int J Oral Maxillofac Implants 2 (1987) 155-165
24. Marx R.E., Carlson E.R., Eichstaedt R.M., Schimmele S.R., Strauss J.E., and Georgeff K.R. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85 (1998) 638-646
25. Nystrom E., Ahlqvist J., Gunne J., and Kahnberg K.E. 10-year follow-up of onlay bone grafts and implants in severely resorbed maxillae. Int J Oral Maxillofac Surg 33 (2004) 258-262
26. Pierce G.F., Mustoe T.A., Lingelbach J., Masakowski V.R., Griffin G.L., Senior R.M., and Deuel T.F. Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms. J Cell Biol 109 (1989) 429-440
27. Roberts A.B., and Sporn M.B. Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta). Growth Factors 8 (1993) 1-9
28. Sailer H.F. A new method of inserting endosseous implants in totally atrophic maxillae. J Craniomaxillofac Surg 17 (1989) 299-305
29. Schlegel K.A., Donath K., Rupprecht S., Falk S., Zimmermann R., Felszeghy E., and Wiltfang J. De novo bone formation using bovine collagen and platelet-rich plasma. Biomaterials 25 (2004) 5387-5393
30. Sennerby L., and Rasmusson L. In: Zarb G., Lekholm U., Albrektsson T., and Tenenbaum H. (Eds). Osseointegration Surgery: Host Determinants and Outcome Criteria (2002), Quintessence Publishing Company Inc., Hong Kong 55-66 Chapter 5
31. Thor A. Reconstruction of the anterior maxilla with platelet gel, autogenous bone, and titanium mesh: a case report. Clin Implant Dent Relat Res 4 (2002) 150-155
32. Thor A., Wannfors K., Sennerby L., and Rasmusson L. Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1-year results of a controlled prospective 5-year study. Clin Implant Dent Relat Res 7 (2005) 209-220
33. Weibrich G., Buch R., Kleis W., Hafner G., Hitzler W.E., and Wagner W. Quantification of thrombocyte growth factors in platelet concentrates produced by discontinuous cell separation. Growth Factors 20 (2002) 93-97
34. Weibrich G., Hansen T., Kleis W., Buch R., and Hitzler W.E. Effect of platelet concentration in platelet-rich plasma on peri-implant bone regeneration. Bone 34 (2004) 665-671
35. Weibrich G., and Kleis W.K. Curasan PRP kit vs. PCCS PRP system. Collection efficiency and platelet counts of two different methods for the preparation of platelet-rich plasma. Clin Oral Implants Res 13 (2002) 437-443
36. Weibrich G., Kleis W.K., and Hafner G. Growth factor levels in the platelet-rich plasma produced by 2 different methods: curasan-type PRP kit versus PCCS PRP system. Int J Oral Maxillofac Implants 17 (2002) 184-190
37. Weibrich G., Kleis W.K., Hafner G., and Hitzler W.E. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 30 (2002) 97-102
38. Weibrich G., Kleis W.K., Hafner G., Hitzler W.E., and Wagner W. Comparison of platelet, leukocyte, and growth factor levels in point-of-care platelet-enriched plasma, prepared using a modified Curasan kit, with preparations received from a local blood bank. Clin Oral Implants Res 14 (2003) 357-362
39. Weibrich G., Kleis W.K., Kunz-Kostomanolakis M., Loos A.H., and Wagner W. Correlation of platelet concentration in platelet-rich plasma to the extraction method, age, sex, and platelet count of the donor. Int J Oral Maxillofac Implants 16 (2001) 693-699
40. Whitman D.H., Berry R.L., and Green D.M. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 55 (1997) 1294-1299
41. Wiltfang J., Kloss F.R., Kessler P., Nkenke E., Schultze-Mosgau S., Zimmermann R., and Schlegel K.A. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects. An animal experiment. Clin Oral Implants Res 15 (2004) 187-193