Mitochondrial dysfunction and nuclear-mitochondrial shuttling of TERT are involved in cell proliferation arrest induced by G-quadruplex ligands

FEBS Letters

Volumn 587, Issue 11, 2013, Pages 1656-1662

  Zhuang, Xin Ying ^a   Yao, Yong Gang ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

Author keywords

Cell apoptosis; G quadruplex ligand; Mitochondrial function; Telomerase

Indexed keywords

3,3' DIETHYLOXADICARBOCYANINE; 5,10,15,20 TETRA(N METHYL 4 PYRIDYL)PORPHINE; ANTINEOPLASTIC AGENT; GUANINE QUADRUPLEX; LIGAND; REACTIVE OXYGEN METABOLITE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRESS; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GLIOMA; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; LIVER CELL CARCINOMA; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SHORT COURSE THERAPY; UTERINE CERVIX CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARBOCYANINES; CELL NUCLEUS; CELL PROLIFERATION; G-QUADRUPLEXES; GENE EXPRESSION; HELA CELLS; HEP G2 CELLS; HUMANS; LIGANDS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PORPHYRINS; PROTEIN TRANSPORT; TELOMERASE;

EID: 84878254677     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.04.010     Document Type: Article

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