The rat intervertebral disk degeneration pain model: Relationships between biological and structural alterations and pain

Arthritis Research and Therapy

Volumn 13, Issue 5, 2011, Pages

  Kim, Jae Sung ^a   Kroin, Jeffrey S ^a   Li, Xin ^a   An, Howard S ^a   Buvanendran, Asokumar ^a   Yan, Dongyao ^a   Tuman, Kenneth J ^a   Wijnen, Andre J van ^b   Chen, Di ^a   Im, Hee Jeong ^a,c  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c University of Illinois at Chicago   (United States)

Author keywords

Animal model; Chronic back pain; Drug test; Lumbar disk degeneration; Pain intervention; Pain pathway

Indexed keywords

CELECOXIB; KETOROLAC TROMETAMOL; MORPHINE SULFATE; PREGABALIN; PROTEOGLYCAN; 4 AMINOBUTYRIC ACID; DRUG DERIVATIVE;

ADULT; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MEGADOSE; GENE EXPRESSION PROFILING; HYPERALGESIA; INTERVERTEBRAL DISK DEGENERATION; NEUROPATHIC PAIN; NONHUMAN; PATHOGENESIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; LOW BACK PAIN; LUMBAR VERTEBRA; METHODOLOGY; PAIN ASSESSMENT; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; INTERVERTEBRAL DISC DEGENERATION; LOW BACK PAIN; LUMBAR VERTEBRAE; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY;

EID: 80053919964     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3485     Document Type: Article

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