Toll-like receptors and chondrocytes: The lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of toll-like receptor 4 and antagonized by bone morphogenetic protein 7

Arthritis and Rheumatism

Volumn 56, Issue 6, 2007, Pages 1880-1893

  Bobacz, K ^a   Sunk, I G ^a   Hofstaetter, J G ^a   Amoyo, L ^a   Toma, C D ^a,b   Akira, S ^c   Weichhart, T ^a   Saemann, M ^a   Smolen, J S ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Prince Court Medical Centre ^*  (Malaysia)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA ACTIN; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN POLYSULFATE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOGENIC PROTEIN 1; PROTEOGLYCAN; SULFATE; SULFUR 35; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; BONE MORPHOGENETIC PROTEIN; CARTILAGE MATRIX PROTEIN; GLYCOPROTEIN; LIPOPOLYSACCHARIDE; SCLEROPROTEIN; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; C57BL 6 MOUSE; CARTILAGE CELL; CHONDROGENESIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MONOLAYER CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; WESTERN BLOTTING; WILD TYPE; ADOLESCENT; ADULT; AGED; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; MOUSE MUTANT; PHYSIOLOGY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; CHONDROCYTES; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, MESSENGER; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 34447504847     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.22637     Document Type: Article

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