Nanoparticles and spermatogenesis: How do nanoparticles affect spermatogenesis and penetrate the blood-testis barrier

Nanomedicine

Volumn 7, Issue 4, 2012, Pages 579-596

  Lan, Zhou ^a   Yang, Wan Xi ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

blood testis barrier; human health; nanoparticles; spermatogenesis

Indexed keywords

CARBON; CHITOSAN; DOXORUBICIN; FERRIC ION; FULLERENE; GOLD NANOPARTICLE; HYDROGEN PEROXIDE; MAGNETIC NANOPARTICLE; MALONALDEHYDE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SELENIUM; SELENOMETHIONINE; SILICON DIOXIDE; SILVER NANOPARTICLE; SUPEROXIDE DISMUTASE; TESTOSTERONE; TITANIUM DIOXIDE;

ANTINEOPLASTIC ACTIVITY; BLOOD TESTIS BARRIER; BODY WEIGHT; CHEMICAL COMPOSITION; DNA DAMAGE; ELECTROMAGNETIC FIELD; ENZYME SYNTHESIS; EPIDIDYMIS; HISTOPATHOLOGY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALE GENITAL SYSTEM; MUTAGENICITY; NANOTECHNOLOGY; PRIORITY JOURNAL; PROGENY; REPRODUCTION; REVIEW; SPERMATOGENESIS; SPERMATOZOON MOTILITY; TESTOSTERONE BLOOD LEVEL; TUMOR VASCULARIZATION; ZONA PELLUCIDA;

BLOOD-TESTIS BARRIER; HUMANS; MALE; NANOPARTICLES; NANOTECHNOLOGY; SPERMATOGENESIS;

EID: 84859464244     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.20     Document Type: Review

References (84)

1. Buzea C, Pacheco I, Robbie K. Nanomaterials and nanoparticles: sources and toxicity. Biointerphases 2(4), MR17-MR71 (2007).
2. Valiev R. Materials science: nanomaterial advantage. Nature 419(6910), 887-889 (2002). (Pubitemid 35339609)
3. Aitken RJ, Chaudhry MQ, Boxall ABA, Hull M. Manufacture and use of nanoparticles: current status in the UK and global trends. Occup. Med. (Lond). 56(5), 300-306 (2006). (Pubitemid 44304820)
4. Zamborini FP, Bao L, Dasari R. Nanoparticles in measurement science. Anal. Chem. 84(2), 541-576 (2011).
5. Delouise LA. Applications of nanotechnology in dermatology. J. Invest. Dermatol. 132(3 Pt 2), 964-975 (2012).
6. Lim ZZ, Li JE, Ng CT, Yung LY, Bay BH. Gold nanoparticles in cancer therapy. Acta Pharmacol. Sin. 32(8), 983-990 (2011).
7. Lens M. Recent progresses in application of fullerenes in cosmetics. Recent Pat. Biotechnol. 5(2), 67-73 (2011).
8. Stern ST, McNeil SE. Nanotechnology safety concerns revisited. Toxicol. Sci. 101(1), 4-21 (2008). (Pubitemid 350239008)
9. Ema M, Kobayashi N, Naya M, Hanai S, Nakanishi J. Reproductive and developmental toxicity studies of manufactured nanomaterials. Reprod. Toxicol. 30(3), 343-352 (2010).
10. 2 particulates: the contribution of physicochemical characteristics. Part. Fibre Toxicol. 6, 33 (2009).
11. Panyala N, Pena-Mendez E, Havel J. Silver or silver nanoparticles: a hazardous threat to the environment and human health. J. Appl. Biomed. 6, 117-129 (2008).
12. Schrand AM, Rahman MF, Hussain SM, Schlager JJ, Smith DA, Syed A F. Metal-based nanoparticles and their toxicity assessment. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2(5), 544-568 (2010).
13. Hussain SM, Braydich-Stolle LK, Schrand AM et al. Toxicity evaluation for safe use of nanomaterials: recent achievements and technical challenges. Adv. Mater. 21(16), 1549-1559 (2009).
14. Bonde JP. Male reproductive organs are at risk from environmental hazards. Asian J. Androl. 12(2), 152-156 (2010).
15. Auger J, Kunstmann JM, Czyglik F, Jouannet P. Decline in semen quality among fertile men in Paris during the past 20 years. N. Engl. J. Med. 332(5), 281-285 (1995).
16. Farrow S. Falling sperm quality: fact or fction? BMJ 309(6946), 1-2 (1994). (Pubitemid 24202624)
17. Hoover MD, Stefaniak AB, Day GA, Geraci CL. Exposure assessment considerations for nanoparticles in the workplace. In: Nanotoxicology: Characterization, Dosing, and Health Effect. Monteiro-Riviere NA, Tran CL (Eds). Informa Healthcare, Zug, Switzerland (2007).
18. Cormier SA, Lomnicki S, Backes W, Dellinger B. Origin and health impacts of emissions of toxic by-products and fne particles from combustion and thermal treatment of hazardous wastes and materials. Environ. Health Perspect. 114(6), 810-817 (2006). (Pubitemid 43871726)
19. Bonde JP, Ramlau-Hansen CH, Olsen J. Trends in sperm counts: the saga continues. Epidemiology 22 (5), 617-619 (2011).
20. Shi L, Yang R, Yue W et al. Effect of elemental nano-selenium quality, glutathione peroxidase activity, and testis ultrastructure in male Boer goats. Anim. Reprod. Sci. 118(2-4), 248-254 (2010).
21. Dym M, Fawcett DW. The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol. Reprod. 3(3), 308-326 (1970).
22. Shi L, Xun W, Yue W et al. Effect of sodium selenite, Se-yeast and nano-elemental selenium on growth performance, Se concentration and antioxidant status in growing male goats. Small Ruminant Res. 96(1), 49-52 (2011).
23. Park EJ, Bae E, Yi J et al. Repeated-dose toxicity and infammatory responses in mice by oral administration of silver nanoparticles. Environ. Toxicol. Pharmacol. 30 (2), 162-168 (2010).
24. Hayes AW. Principles and Methods of Toxicology. Hayes AW (Ed.). CRC Press/Taylor & Francis, PA, USA (2008).
25. Foster L, Sumar S. Selenium in health and disease: a review. Crit. Rev. Food Sci. Nutr. 37(3), 211-228 (1997). (Pubitemid 127500955)
26. Ip C. Lessons from basic research in selenium and cancer prevention. J. Nutr. 128(11), 1845-1854 (1998). (Pubitemid 28509845)
27. Spallholz J. On the nature of selenium toxicity and carcinostatic activity. Free Radic. Biol. Med. 17(1), 45-64 (1994). (Pubitemid 24212711)
28. Gao X, Zhang J, Zhang L. Hollow sphere selenium nanoparticles: their in vitro anti hydroxyl radical effect. Adv. Mater. 14 (4), 290-293 (2002). (Pubitemid 34228608)
29. Jia X, Li N, Chen J. A subchronic toxicity study of elemental Nano-Se in Sprague-Dawley rats. Life Sci. 76 (17), 1989-2003 (2005). (Pubitemid 40222417)
30. Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 5(3), 161-171 (2005). (Pubitemid 40314948)
31. IE-Sayed I, Huang X, EI-Sayed M. Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles. Cancer Lett. 239(1), 129-135 (2006). (Pubitemid 43946581)
32. Brown C, Bushell G, Whitehouse M, Agrawal D, Tupe S, Paknikar K. Nanogold-pharmaceutics: (i) the use of colloidal gold to treat experimentally-induced arthritis in rat models; (ii) characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine. Gold Bull. 40(3), 245-250 (2007).
33. Tsai C, Shiau A, Chen S, Chen Y, Cheng P, Chang M. Amelioration of collagen-induced arthritis in rats by nanogold. Arthritis Rheum. 56(2), 544-554 (2007).
34. Balasubramanian S, Jittiwat J, Manikandan J, Ong C, Yu L, Ong W. Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rat. Biomaterials 31(8), 2034-2042 (2010).
35. De Jong WH, Hagens WI, Krystek P, Burger MC, Sips AJ, Geertsma RE. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 29(12), 1912-1919 (2008).
36. Makhluf SBD, Qasem R, Rubinstein S, Gedanken A, Breitbart H. Loading magnetic nanoparticles into sperm cells does not affect their functionality. Langmuir 22(23), 9480-9482 (2006). (Pubitemid 44826350)
37. Kim JS, Yoon TJ, Yu KN et al. Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol. Sci. 89(1), 338-347 (2006). (Pubitemid 43013783)
38. Kwon JT, Hwang SK, Jin H et al. Body distribution of inhaled fuorescent magnetic nanoparticles in the mice. J. Occup. Health 50(1), 1-6 (2008). (Pubitemid 351680001)
39. Cho Y W, Park SA, Han TH et al. In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles: mechanisms, key factors, and their implications. Biomaterials 28(6), 1236-1247 (2007). (Pubitemid 44816372)
40. Martin L, Wilson CG, Koosha F et al. The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels. J. Control. Release 80(1-3), 87-100 (2002). (Pubitemid 34273751)
41. Hyung PJ, Kwon S, Lee M et al. Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor activity. Biomaterials 27(1), 119-126 (2006). (Pubitemid 41225375)
42. Kim JH, Kim YS, Park K et al. Anti-tumor effcacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice. J. Control. Release 127(1), 41-49 (2008).
43. Choi M, Cho M, Han B et al. Chitosan nanoparticles show rapid extrapulmonary tissue distribution and excretion with mild pulmonary infammation to mice. Toxicol. Lett. 199(2), 144-152 (2010).
44. Lacerda L, Bianco A, Prato M, Kostarelos K. Carbon nanotubes as nanomedicines: from toxicology to pharmacology. Adv. Drug Deliv. Rev. 58 (14), 1460-1470 (2006). (Pubitemid 44822607)
45. Liu Z, Cai W, He L et al. In vivo biodistribution and highly effcient tumour targeting of carbon nanotubes in mice. Nat. Nanotechnol. 2(1), 47-52 (2007). (Pubitemid 46210038)
46. Chen J, Chen S, Zhao X, Kuznetsova LV, Wong SS, Ojima I. Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery. J. Am. Chem. Soc. 130(49), 16778-16785 (2008).
47. Usui Y, Aoki K, Narita N et al. Carbon nanotubes with high bone-tissue compatibility and bone-formation acceleration effects. Small 4(2), 240-246 (2008). (Pubitemid 351271157)
48. Yoshida S, Hiyoshi K, Ichinose T et al. Effect of nanoparticles on the male reproductive system of mice. Int. J. Androl. 32(4), 337-342 (2009).
49. Bai Y, Zhang Y, Zhang J et al. Repeated administrations of carbon nanotubes in male mice cause reversible testis damage without affecting fertility. Nat. Nanotechnol. 5(9), 683-689 (2010).
50. Hill W, Pillsbury D. Argyria: The Pharmacology of Silver. Williams & Wilkins Company, MD, USA (1939).
51. Hussain SM, Javorina AK, Schrand AM, Duhart HM, Ali SF, Schlager JJ. The interaction of manganese nanoparticles with pc-12 cells induces dopamine depletion. Toxicol. Sci. 92(2), 456-463 (2006). (Pubitemid 44018962)
52. Hussain SM, Hess KL, Gearhart JM, Geiss K T, Schlager JJ. In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol. In vitro 19(7), 975-983 (2005). (Pubitemid 41563236)
53. Braydich-Stolle L, Hussain S, Schlager JJ, Hofmann MC. In vitro cytotoxicity of nanoparticles in mammalian germline stem cells. Toxicol. Sci. 88(2), 412-419 (2005). (Pubitemid 41672149)
54. Kim YS, Song MY, Park JD et al. Subchronic oral toxicity of silver nanoparticles. Part. Fibre Toxicol. 7, 20 (2010).
55. Wolf R, Matz H, Orion E, Lipozencic J. Sunscreens-the ultimate cosmetic. Acta Dermatovenerol. Croat. 11(3), 158-162 (2003).
56. Sayes CM, Wahi R, Kurian PA et al. Correlating nanoscale titania structure with toxicity: a cytotoxicity and infammatory response study with human dermal fbroblasts and human lung epithelial cells. Toxicol. Sci. 92(1), 174-185 (2006). (Pubitemid 43994876)
57. Li H, Luo W, Tao Y et al. Effects of nanoscale quantum dots in male Chinese loaches (Misgurnus anguillicaudatus): estrogenic interference action, toxicokinetics and oxidative stress. Sci. China Ser. B Chem. 52(10), 1683-1690 (2008).
58. 2. Biol. Trace Elem. Res. 140(2), 186-197 (2011).
59. Gurr JR, Wang AS, Chen CH, Jan KY. Ultrafne titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213(1-2), 66-73 (2005). (Pubitemid 41191282)
60. Takeda K, Suzuki K, Ishihara A et al. Nanoparticles transferred from pregnant mice to their offspring can damage the genital and cranial nerve systems. J. Health 55, 95-102 (2009).
61. 60 fullerene on reproductive function in streptozotocin-diabetic male rats. Toxicology 282(3), 69-81 (2011).
62. Igeolet E, Corbisier P, Houbion A et al. Glutathione peroxidase, superoxide dismutase and catalase inactivation by peroxides and oxygen derived free radicals. Mech. Ageing Dev. 51(3), 283-297 (1990). (Pubitemid 20041562)
63. Lin BC, Xi ZG, Zhang YG. Oxidative damage on testicles of male rats induced by micro-nano-scale SiO2. J. Environ. Health 24(8), 574-576 (2007).
64. Shrilatha B, Muralidhara. Early oxidative stress in testis and epididymal sperm in streptozotocin-induced diabetic mice: its progression and genotoxic consequences. Reprod. Toxicol. 23(4), 578-587 (2007). (Pubitemid 46754745)
65. Fan YO, Zhang YH, Zhang XP, Liu B. Comparative study of nanosized and microsized silicon dioxide on spermatogenesis function of male rats. Wei Sheng Yan Jiu 35(5), 549-553 (2006).
66. Ramdhan DH, Ito Y, Yanagiba Y. Nanoparticle-rich diesel exhaust may disrupt testosterone biosynthesis and metabolism via growth hormone. Toxicol. Lett. 191(2-3), 103-108 (2009).
67. Komatsu T, Tabata M, Kubo-Irie M et al. The effects of nanoparticles on mouse testis Leydig cells in vitro. Toxicol. In Vitro 22(8), 1825-1831 (2008).
68. Wiwanitkit V, Sereemaspun A, Rojanathanes R. Effect of gold nanoparticles on spermatozoa: the frst world report. Fertil. Steril. 91(1), e7-e8 (2009).
69. Cheng CY, Mruk DD. Cell junction dynamics in the testis: sertoli-germ cell interactions and male contraceptive development. Physiol. Rev. 82(4), 825-874 (2002).
70. Furuse M, Sasaki H, Fujimoto K, Tsukita S. A single gene product, claudin-1 or-2, reconstitutes tight junction strands and recruits occludin in fbroblasts. J. Cell Biol. 143(2), 391-401 (1998). (Pubitemid 28487858)
71. Hellani A, Ji J, Mauduit C, Deschildre C, Tabone E, Benahmed M. Developmental and hormonal regulation of the expression of oligodendrocyte- specifc protein/claudin 11 in mouse testis. Endocrinology 141(8), 3012-3019 (2000). (Pubitemid 32250466)
72. Fijak M, Bhushan S, Meinhardt A. Immunoprivileged sites: the testis. Methods Mol. Biol. 677, 459-470 (2011).
73. Krawetz SA, De Rooij DG, Hedger MP. Molecular aspects of male fertility. International workshop on molecular andrology. EMBO Rep. 10 (10), 1087-1092 (2009).
74. Fijak M, Meinhardt A. The testis in immune privilege. Immunol. Rev. 213, 66-81(2006). (Pubitemid 44401494)
75. Meng J, Holdcraft RW, Shima JE, Griswold MD, Braun RE. Androgens regulate the permeability of the blood-testis barrier. Proc. Natl Acad. Sci. USA 102(46), 16696-16700 (2005). (Pubitemid 41688839)
76. Warren DW, Pasupuleti V, Lu Y, Platler BW, Horton R. Tumor necrosis factor and interleukin-1 stimulate testosterone secretion in adult male rat Leydig cells in vitro. J. Androl. 11(4), 353-360 (1990). (Pubitemid 20264039)
77. Delfno FJ, Boustead JN, Fix C, Walker WH. NF-κB and TNF-a stimulate androgen receptor expression in sertoli cells. Mol. Cell. Endocrinol. 201(1-2), 1-12 (2003). (Pubitemid 36434276)
78. Zhang Y, Ling F, Zhu Q et al. New development of study on the toxicity of nano materials. Nanoscience 11, 137-141 (2006).
79. Podio V, Zara GP, Carazzone M, Cavalli R, Gasco MR. Biodistribution of stealth and non-stealth solid lipid nanospheres after intravenous administration to rats. J. Pharm. Pharmacol. 52(9), 1057-1063 (2002).
80. Hasirci N. Micro and nano systems in biomedicine and drug delivery. Nanoparticles Nanosystems Biomed. Appl. 1-26 (2007).
81. Fernandes C, Soni U, Patravale V. Nano-interventions for neurodegenerative disorders. Pharmacol. Res. 62(2), 166-178 (2010).
82. Nag S. Morphology and properties of brain endothelial cells. Methods Mol. Biol. 686, 3-47 (2011).
83. Sharom FJ. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics 9(1), 105-127 (2008). (Pubitemid 351560534)
84. Misra A, Ganesh S, Shahiwala A, Shah SP. Drug delivery to the central nervous system: a rev iew. J. Pharm. Sci. 6(2), 252-273 (2003). (Pubitemid 37207232)