-
1
-
-
77949922428
-
Hepatocellular carcinoma (HCC): A global perspective
-
Ferenci P, Fried M, Labrecque D, et al: Hepatocellular carcinoma (HCC): a global perspective. J Clin Gastroenterol 44: 239-245, 2010.
-
(2010)
J Clin Gastroenterol
, vol.44
, pp. 239-245
-
-
Ferenci, P.1
Fried, M.2
Labrecque, D.3
-
2
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, et al: Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 10: 25-34, 2009.
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
-
3
-
-
84867896284
-
Prioritizing strategies for comprehensive liver cancer control in Asia: A conjoint analysis
-
Bridges JF, Dong L, Gallego G, Blauvelt BM, Joy SM and Pawlik TM: Prioritizing strategies for comprehensive liver cancer control in Asia: a conjoint analysis. BMC Health Serv Res 12: 376, 2012.
-
(2012)
BMC Health Serv Res
, vol.12
, pp. 376
-
-
Bridges, J.F.1
Dong, L.2
Gallego, G.3
Blauvelt, B.M.4
Joy, S.M.5
Pawlik, T.M.6
-
4
-
-
77953776656
-
Future perspectives in hepatocellular carcinoma
-
Wörns MA and Galle PR: Future perspectives in hepatocellular carcinoma. Dig Liver Dis 42 (Suppl 3): S302-S309, 2010.
-
(2010)
Dig Liver Dis
, vol.42
, Issue.SUPPL. 3
-
-
Wörns, M.A.1
Galle, P.R.2
-
5
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
6
-
-
0034856294
-
Clinical management of hepatocellular carcinoma. Conclusions of the barcelona-2000 EASL conference
-
DOI 10.1016/S0168-8278(01)00130-1, PII S0168827801001301
-
Bruix J, Sherman M, Llovet JM, et al: Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J Hepatol 35: 421-430, 2001. (Pubitemid 32844200)
-
(2001)
Journal of Hepatology
, vol.35
, Issue.3
, pp. 421-430
-
-
Bruix, J.1
Sherman, M.2
Llovet, J.M.3
Beaugrand, M.4
Lencioni, R.5
Burroughs, A.K.6
Christensen, E.7
Pagliaro, L.8
Colombo, M.9
Rodes, J.10
-
7
-
-
0029065587
-
Therapy of unresectable hepatocellular carcinoma
-
Levin B and Amos C: Therapy of unresectable hepatocellular carcinoma. N Engl J Med 332: 1294-1296, 1995.
-
(1995)
N Engl J Med
, vol.332
, pp. 1294-1296
-
-
Levin, B.1
Amos, C.2
-
9
-
-
0033922361
-
Genotoxicity of several clinically used topoisomerase II inhibitors
-
DOI 10.1016/S0378-4274(00)00192-2, PII S0378427400001922
-
Boos G and Stopper H: Genotoxicity of several clinically used topoisomerase II inhibitors. Toxicol Lett 116: 7-16, 2000. (Pubitemid 30440762)
-
(2000)
Toxicology Letters
, vol.116
, Issue.1-2
, pp. 7-16
-
-
Boos, G.1
Stopper, H.2
-
10
-
-
70350752049
-
Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation
-
Auyeung KK and Ko JK: Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation. Int J Mol Med 24: 571-577, 2009.
-
(2009)
Int J Mol Med
, vol.24
, pp. 571-577
-
-
Auyeung, K.K.1
Ko, J.K.2
-
11
-
-
39149098194
-
Natural products as leads to anticancer drugs
-
Gordaliza M: Natural products as leads to anticancer drugs. Clin Transl Oncol 9: 767-776, 2007.
-
(2007)
Clin Transl Oncol
, vol.9
, pp. 767-776
-
-
Gordaliza, M.1
-
12
-
-
0034082239
-
The influence of natural products upon drug discovery
-
DOI 10.1039/a902202c
-
Newman DJ, Cragg GM and Snader KM: The influence of natural products upon drug discovery. Nat Prod Rep 17: 215-234, 2000. (Pubitemid 30390787)
-
(2000)
Natural Product Reports
, vol.17
, Issue.3
, pp. 215-234
-
-
Newman, D.J.1
Cragg, G.M.2
Snader, K.M.3
-
13
-
-
19944427133
-
The Janus kinases (Jaks)
-
Yamaoka K, Saharinen P, Pesu M, Holt VE III, Silvennoinen O and O'Shea JJ: The Janus kinases (Jaks). Genome Biol 5: 253, 2004.
-
(2004)
Genome Biol
, vol.5
, pp. 253
-
-
Yamaoka, K.1
Saharinen, P.2
Pesu, M.3
Holt III, V.E.4
Silvennoinen, O.5
O'Shea, J.J.6
-
14
-
-
0037204953
-
A road map for those who don't know JAK-STAT
-
DOI 10.1126/science.1071545
-
Aaronson DS and Horvath CM: A road map for those who don't know JAK-STAT. Science 296: 1653-1655, 2002. (Pubitemid 34579157)
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1653-1655
-
-
Aaronson, D.S.1
Horvath, C.M.2
-
15
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
DOI 10.1016/S0092-8674(02)00701-8
-
O'Shea JJ, Gadina M and Schreiber RD: Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109 (Suppl): S121-S131, 2002. (Pubitemid 34457857)
-
(2002)
Cell
, vol.109
, Issue.2 SUPPL. 1
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
16
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE Jr, Kerr IM and Stark GR: Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1421, 1994. (Pubitemid 24217131)
-
(1994)
Science
, vol.264
, Issue.5164
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
17
-
-
0037138370
-
Signaling through the JAK/STAT pathway, recent advances and future challenges
-
DOI 10.1016/S0378-1119(02)00398-0, PII S0378111902003980
-
Kisseleva T, Bhattacharya S, Braunstein J and Schindler C: Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285: 1-24, 2002. (Pubitemid 34246317)
-
(2002)
Gene
, vol.285
, Issue.1-2
, pp. 1-24
-
-
Kisseleva, T.1
Bhattacharya, S.2
Braunstein, J.3
Schindler, C.W.4
-
18
-
-
79957910877
-
6-Bromoindirubin-3′-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells
-
Liu L, Nam S, Tian Y, et al: 6-Bromoindirubin-3′-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells. Cancer Res 71: 3972-3979, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 3972-3979
-
-
Liu, L.1
Nam, S.2
Tian, Y.3
-
19
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg J and Darnell JE Jr: The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19: 2468-2473, 2000. (Pubitemid 30339202)
-
(2000)
Oncogene
, vol.19
, Issue.21
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell Jr., J.E.2
-
20
-
-
24644457736
-
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
-
DOI 10.1038/sj.onc.1208719, PII 1208719
-
Xu Q, Briggs J, Park S, et al: Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene 24: 5552-5560, 2005. (Pubitemid 43119350)
-
(2005)
Oncogene
, vol.24
, Issue.36
, pp. 5552-5560
-
-
Xu, Q.1
Briggs, J.2
Park, S.3
Niu, G.4
Kortylewski, M.5
Zhang, S.6
Gritsko, T.7
Turkson, J.8
Kay, H.9
Semenza, G.L.10
Cheng, J.Q.11
Jove, R.12
Yu, H.13
-
21
-
-
84865400277
-
Electroacupuncture inhibits apoptosis in annulus fibrosis cells through suppression of the mitochondria-dependent pathway in a rat model of cervical intervertebral disc degradation
-
Liao J, Ke M, Xu T and Lin L: Electroacupuncture inhibits apoptosis in annulus fibrosis cells through suppression of the mitochondria-dependent pathway in a rat model of cervical intervertebral disc degradation. Genet Mol Biol 35: 686-692, 2012.
-
(2012)
Genet Mol Biol
, vol.35
, pp. 686-692
-
-
Liao, J.1
Ke, M.2
Xu, T.3
Lin, L.4
-
22
-
-
84873933500
-
In vitro inhibition of angiogenesis by hydroalcoholic extract of oak (Quercus infectoria) acorn shell via suppressing VEGF, MMP-2, and MMP-9 secretion
-
Yarani R, Mansouri K, Mohammadi-Motlagh HR, Mahnam A and Emami Aleagha MS: In vitro inhibition of angiogenesis by hydroalcoholic extract of oak (Quercus infectoria) acorn shell via suppressing VEGF, MMP-2, and MMP-9 secretion. Pharm Biol 51: 361-368, 2012.
-
(2012)
Pharm Biol
, vol.51
, pp. 361-368
-
-
Yarani, R.1
Mansouri, K.2
Mohammadi-Motlagh, H.R.3
Mahnam, A.4
Emami Aleagha, M.S.5
-
23
-
-
84863151419
-
Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer
-
Chen J, Wang J, Lin L, et al: Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Mol Cancer Ther 11: 277-287, 2012
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 277-287
-
-
Chen, J.1
Wang, J.2
Lin, L.3
-
24
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner R, Mora LB and Jove R: Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8: 945-954, 2002. (Pubitemid 35177340)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.4
, pp. 945-954
-
-
Buettner, R.1
Mora, L.B.2
Jove, R.3
-
25
-
-
35248880645
-
Dissection of signal transduction pathways as a tool for the development of targeted therapies of hepatocellular carcinoma
-
DOI 10.2174/157488707781662715
-
Calvisi DF, Pascale RM and Feo F: Dissection of signal transduction pathways as a tool for the development of targeted therapies of hepatocellular carcinoma. Rev Recent Clin Trials 2: 217-236, 2007. (Pubitemid 47558825)
-
(2007)
Reviews on Recent Clinical Trials
, vol.2
, Issue.3
, pp. 217-236
-
-
Calvisi, D.F.1
Pascale, R.M.2
Feo, F.3
-
26
-
-
0034023759
-
The Jak-STAT pathway
-
DOI 10.1016/S0161-5890(00)00018-3, PII S0161589000000183
-
Imada K and Leonard WJ: The Jak-STAT pathway. Mol Immunol 37: 1-11, 2000. (Pubitemid 30316189)
-
(2000)
Molecular Immunology
, vol.37
, Issue.1-2
, pp. 1-11
-
-
Imada, K.1
Leonard, W.J.2
-
27
-
-
0003851569
-
-
Chinese Edition. Shanghai Science and Technology Publishing House, Shanghai
-
Bencao Z (ed): Chinese Herbal Medicine. Chinese Edition. Shanghai Science and Technology Publishing House, Shanghai, 1996.
-
(1996)
Chinese Herbal Medicine
-
-
Bencao, Z.1
-
28
-
-
82655162059
-
Nitidine chloride inhibits breast cancer cells migration and invasion by suppressing c-Src/FAK associated signaling pathway
-
Pan X, Han H, Wang L, et al: Nitidine chloride inhibits breast cancer cells migration and invasion by suppressing c-Src/FAK associated signaling pathway. Cancer Lett 313: 181-191, 2011.
-
(2011)
Cancer Lett
, vol.313
, pp. 181-191
-
-
Pan, X.1
Han, H.2
Wang, L.3
-
29
-
-
84867567386
-
Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells
-
Wang Z, Jiang W, Zhang Z, Qian M and Du B: Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells. J Ethnopharmacol 144: 145-150, 2012.
-
(2012)
J Ethnopharmacol
, vol.144
, pp. 145-150
-
-
Wang, Z.1
Jiang, W.2
Zhang, Z.3
Qian, M.4
Du, B.5
-
30
-
-
77953907434
-
Anti-hepatoma activity of nitidine chloride and its effect on topoisomerase
-
In Chinese
-
Liu LM and Liu HG: Anti-hepatoma activity of nitidine chloride and its effect on topoisomerase. Chin Pharmacol Bull 4: 497-500, 2010 (In Chinese).
-
(2010)
Chin Pharmacol Bull
, vol.4
, pp. 497-500
-
-
Liu, L.M.1
Liu, H.G.2
-
31
-
-
0021260108
-
Synthesis and biological activity of structural analogues of the anticancer benzophenanthridine alkaloid nitidine chloride
-
Cushman M, Mohan P and Smith EC: Synthesis and biological activity of structural analogs of the anticancer benzophenanthridine alkaloid nitidine chloride. J Med Chem 27: 544-547, 1984. (Pubitemid 14133747)
-
(1984)
Journal of Medicinal Chemistry
, vol.27
, Issue.4
, pp. 544-547
-
-
Cushman, M.1
Mohan, P.2
Smith, E.C.R.3
-
32
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
DOI 10.1038/sj.onc.1210220, PII 1210220
-
Adams J and Cory S: The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337, 2007. (Pubitemid 46328466)
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
33
-
-
84861553415
-
Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway
-
Cai Q, Lin J, Wei L, et al: Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway. Int J Mol Sci 13: 6117-6128, 2012.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 6117-6128
-
-
Cai, Q.1
Lin, J.2
Wei, L.3
-
34
-
-
84874547247
-
Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms
-
Hall C, Troutman SM, Price DK, Figg WD and Kang MH: Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms. Clin Genitourin Cancer 11: 10-19, 2013.
-
(2013)
Clin Genitourin Cancer
, vol.11
, pp. 10-19
-
-
Hall, C.1
Troutman, S.M.2
Price, D.K.3
Figg, W.D.4
Kang, M.H.5
-
35
-
-
20444485848
-
Expression of cell survival/death genes: Bcl-2 and Bax at the rate of colon cancer prognosis
-
Paul-Samojedny M, Kokocińska D, Samojedny A, et al: Expression of cell survival/death genes: Bcl-2 and Bax at the rate of colon cancer prognosis. Biochim Biophys Acta 1741: 25-29, 2005.
-
(2005)
Biochim Biophys Acta
, vol.1741
, pp. 25-29
-
-
Paul-Samojedny, M.1
Kokocińska, D.2
Samojedny, A.3
-
36
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle RJ and Strasser A: The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9: 47-59, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
37
-
-
80052887427
-
NF-Y binds to both G1- and G2-specific cyclin promoters; a possible role in linking CDK2/Cyclin A to CDK1/Cyclin B
-
Chae HD, Kim J and Shin DY: NF-Y binds to both G1- and G2-specific cyclin promoters; a possible role in linking CDK2/Cyclin A to CDK1/Cyclin B. BMB Rep 44: 553-557, 2011.
-
(2011)
BMB Rep
, vol.44
, pp. 553-557
-
-
Chae, H.D.1
Kim, J.2
Shin, D.Y.3
-
38
-
-
0029849620
-
Cancer cell cycles
-
Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
39
-
-
84858284701
-
Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes
-
Tin AS, Sundar SN, Tran KQ, Park AH, Poindexter KM and Firestone GL: Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes. Anticancer Drugs 23: 370-379, 2012.
-
(2012)
Anticancer Drugs
, vol.23
, pp. 370-379
-
-
Tin, A.S.1
Sundar, S.N.2
Tran, K.Q.3
Park, A.H.4
Poindexter, K.M.5
Firestone, G.L.6
-
40
-
-
0034543419
-
Cell-cycle dysregulation in breast cancer: Breast cancer therapies targeting the cell cycle
-
Zafonte BT, Hulit J, Amanatullah DF, et al: Cell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycle. Front Biosci 5: D938-D961, 2000.
-
(2000)
Front Biosci
, vol.5
-
-
Zafonte, B.T.1
Hulit, J.2
Amanatullah, D.F.3
-
41
-
-
0034884829
-
p21/WAF1/Cip1 expression in invasive ductal breast carcinoma: Relationship to p53, proliferation rate, and survival at 5 years
-
DOI 10.1007/s004280100410
-
Domagala W, Welcker M, Chosia M, et al: p21/WAF1/Cip1 expression in invasive ductal breast carcinoma: relationship to p53, proliferation rate, and survival at 5 years. Virchows Arch 439: 132-140, 2001. (Pubitemid 32758906)
-
(2001)
Virchows Archiv
, vol.439
, Issue.2
, pp. 132-140
-
-
Domagala, W.1
Welcker, M.2
Chosia, M.3
Karbowniczek, M.4
Harezga, B.5
Bartkova, J.6
Bartek, J.7
Osborn, M.8
-
42
-
-
77953894340
-
Clinical development and future direction for the treatment of hepatocellular carcinoma
-
Whang-Peng J, Cheng AL, Hsu C and Chen CM: Clinical development and future direction for the treatment of hepatocellular carcinoma. J Exp Clin Med 2: 93-103, 2010.
-
(2010)
J Exp Clin Med
, vol.2
, pp. 93-103
-
-
Whang-Peng, J.1
Cheng, A.L.2
Hsu, C.3
Chen, C.M.4
-
43
-
-
0033066004
-
Immunohistochemical and molecular analysis of BAX, BCL-2 and p53 genes in laryngeal squamous cell carcinomas
-
Fracchiolla N, Capaccio P, Carboni N, et al: Immunohistochemical and molecular analysis of bax, bcl-2 and p53 genes in laryngeal squamous cell carcinomas. Anticancer Res 19: 1043-1051, 1999. (Pubitemid 29257536)
-
(1999)
Anticancer Research
, vol.19
, Issue.2 A
, pp. 1043-1051
-
-
Fracchiolla, N.S.1
Capaccio, P.2
Carboni, N.3
Pagliari, A.V.4
Neri, A.5
Ronchett, D.6
Pruner, G.7
Silvotti, M.G.8
Pignataro, L.9
Buffa, R.10
Broich, G.11
-
44
-
-
31544460437
-
Activation of Stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated Src and survivin expression
-
DOI 10.1158/1078-0432.CCR-04-1749
-
Diaz N, Minton S, Cox C, et al: Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression. Clin Cancer Res 12: 20-28, 2006. (Pubitemid 43166171)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.1
, pp. 20-28
-
-
Diaz, N.1
Minton, S.2
Cox, C.3
Bowman, T.4
Gritsko, T.5
Garcia, R.6
Eweis, I.7
Wloch, M.8
Livingston, S.9
Seijo, E.10
Cantor, A.11
Lee, J.-H.12
Beam, C.A.13
Sullivan, D.14
Jove, R.15
Muro-Cacho, C.A.16
|