-
1
-
-
33749234216
-
Drugs, their targets and the nature and number of drug targets
-
Imming, P.; Sinning, C.; Meyer, A. Drugs, their targets and the nature and number of drug targets. Nat. Rev. Drug Discov. 2006, 5, 821-834.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 821-834
-
-
Imming, P.1
Sinning, C.2
Meyer, A.3
-
2
-
-
4344668661
-
Drug repositioning: identifying and developing new uses for existing drugs
-
Ashburn, T. T.; Thor, K. B. Drug repositioning: identifying and developing new uses for existing drugs. Nat. Rev. Drug Discov. 2004, 3, 673-683.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 673-683
-
-
Ashburn, T.T.1
Thor, K.B.2
-
3
-
-
84886018344
-
A process for identifying the active site in a biological target
-
G.B. Patent 99273346.8.
-
Prusis, P.; Mucenience, R.; Andersson, P.; Lundstedt, T.; Wikberg, J. E. S. A process for identifying the active site in a biological target. 1999. G.B. Patent 99273346.8.
-
(1999)
-
-
Prusis, P.1
Mucenience, R.2
Andersson, P.3
Lundstedt, T.4
Wikberg, J.E.S.5
-
4
-
-
0036130770
-
Classification of G-protein coupled receptors by alignment independent extraction of principal chemical properties of primary amino acid sequences
-
Lapinsh, M.; Gutcaits, A.; Prusis, P.; Post, C.; Lundstedt, T.; Wikberg, J. E. S. Classification of G-protein coupled receptors by alignment independent extraction of principal chemical properties of primary amino acid sequences. Protein Sci . 2002, 11, 795-805.
-
(2002)
Protein Sci
, vol.11
, pp. 795-805
-
-
Lapinsh, M.1
Gutcaits, A.2
Prusis, P.3
Post, C.4
Lundstedt, T.5
Wikberg, J.E.S.6
-
5
-
-
84954206661
-
Proteochemometrics: a tool for modelling the molecular interaction space
-
In Chemogenomics in Drug Discovery: A Medicinal Chemistry Perspective, Kubinyi, H.; M̈uller, G., Eds. Wiley-VCH, Weinheim, Germany
-
Wikberg, J. E. S.; Lapinsh, M.; Prusis, P. Proteochemometrics: a tool for modelling the molecular interaction space. In Chemogenomics in Drug Discovery: A Medicinal Chemistry Perspective, Kubinyi, H.; M̈uller, G., Eds. Wiley-VCH, Weinheim, Germany, 2004, pp. 289-309.
-
(2004)
, pp. 289-309
-
-
Wikberg, J.E.S.1
Lapinsh, M.2
Prusis, P.3
-
6
-
-
25444521952
-
Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling
-
Freyhult, E.; Prusis, P.; Lapinsh, M.; Wikberg, J. E. S.; Moulton, V.; Gustafsson, M. G. Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling. BMC Bioinf . 2005, 6.
-
(2005)
BMC Bioinf .
, vol.6
-
-
Freyhult, E.1
Prusis, P.2
Lapinsh, M.3
Wikberg, J.E.S.4
Moulton, V.5
Gustafsson, M.G.6
-
7
-
-
33645769799
-
Prediction of indirect interactions in proteins
-
Prusis, P.; Uhlen, S.; Petrovska, R.; Lapinsh, M.; Wikberg, J. E. S. Prediction of indirect interactions in proteins. BMC Bioinf . 2006, 7, 167.
-
(2006)
BMC Bioinf
, vol.7
, pp. 167
-
-
Prusis, P.1
Uhlen, S.2
Petrovska, R.3
Lapinsh, M.4
Wikberg, J.E.S.5
-
8
-
-
33750049960
-
Generalized modeling of enzyme-ligand interactions using proteochemometrics and local protein substructures
-
Str̈ombergsson, H.; Kryshtafovych, A.; Prusis, P.; Fidelis, K.; Wikberg, J. E. S.; Komorowski, J.; Hvidsten, T. R. Generalized modeling of enzyme-ligand interactions using proteochemometrics and local protein substructures. Proteins 2006, 65, 568-579.
-
(2006)
Proteins
, vol.65
, pp. 568-579
-
-
Str̈ombergsson, H.1
Kryshtafovych, A.2
Prusis, P.3
Fidelis, K.4
Wikberg, J.E.S.5
Komorowski, J.6
Hvidsten, T.R.7
-
9
-
-
34547782241
-
Proteochemometric modelling of antibody-antigen interactions using SPOT synthesised peptide arrays
-
Mandrika, I.; Prusis, P.; Yahorava, S.; Shikhagie, M.; Wikberg, J. E. S. Proteochemometric modelling of antibody-antigen interactions using SPOT synthesised peptide arrays. Protein Eng. Des. Sel. 2007, 20, 301-307.
-
(2007)
Protein Eng. Des. Sel.
, vol.20
, pp. 301-307
-
-
Mandrika, I.1
Prusis, P.2
Yahorava, S.3
Shikhagie, M.4
Wikberg, J.E.S.5
-
10
-
-
34047224674
-
A look inside HIV resistance through retroviral protease interaction maps
-
Kontijevskis, A.; Prusis, P.; Petrovska, R.; Yahorava, S.; Mutulis, F.; Mutule, I.; Komorowski, J.; Wikberg, J. E. S. A look inside HIV resistance through retroviral protease interaction maps. PloS Comput. Biol. 2007, 3.
-
(2007)
PloS Comput. Biol.
, vol.3
-
-
Kontijevskis, A.1
Prusis, P.2
Petrovska, R.3
Yahorava, S.4
Mutulis, F.5
Mutule, I.6
Komorowski, J.7
Wikberg, J.E.S.8
-
11
-
-
42149124403
-
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
-
Wikberg, J. E. S.; Mutulis, F. Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction. Nat. Rev. Drug Discov. 2008, 7, 307-323.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 307-323
-
-
Wikberg, J.E.S.1
Mutulis, F.2
-
12
-
-
57549114279
-
Interaction model based on local protein substructures generalizes to the entire structural enzyme-ligand space
-
Str̈ombergsson, H.; Daniluk, P.; Kryshtafovych, A.; Fidelis, K.; Wikberg, J. E. S.; Kleywegt, G. J.; Hvidsten, T. R. Interaction model based on local protein substructures generalizes to the entire structural enzyme-ligand space. J. Chem. Inf. Model. 2008, 48, 2278-2288.
-
(2008)
J. Chem. Inf. Model.
, vol.48
, pp. 2278-2288
-
-
Str̈ombergsson, H.1
Daniluk, P.2
Kryshtafovych, A.3
Fidelis, K.4
Wikberg, J.E.S.5
Kleywegt, G.J.6
Hvidsten, T.R.7
-
13
-
-
0038115355
-
QSAR and proteochemometric analysis of the interaction of a series of organic compounds with melanocortin receptor subtypes
-
Lapinsh, M.; Prusis, P.; Mutule, I.; Mutulis, F.; Wikberg, J. E. S. QSAR and proteochemometric analysis of the interaction of a series of organic compounds with melanocortin receptor subtypes. J. Med. Chem. 2003, 46, 2572-2579.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 2572-2579
-
-
Lapinsh, M.1
Prusis, P.2
Mutule, I.3
Mutulis, F.4
Wikberg, J.E.S.5
-
14
-
-
0003100744
-
Multivariate design
-
Wold, S.; Sj̈ostr̈om, M.; Carlson, R.; Lundstedt, T.; Hellberg, S.; Skagerberg, B.; Wikström, C.; Öhman, J. Multivariate design. Anal. Chim. Acta 1986, 191, 17-32.
-
(1986)
Anal. Chim. Acta
, vol.191
, pp. 17-32
-
-
Wold, S.1
Sj̈ostr̈om, M.2
Carlson, R.3
Lundstedt, T.4
Hellberg, S.5
Skagerberg, B.6
Wikström, C.7
Öhman, J.8
-
15
-
-
0024491426
-
Recent advances in comparative molecular field analysis (CoMFA)
-
Cramer, R. D. R.; Patterson, D. E.; Bunce, J. D. Recent advances in comparative molecular field analysis (CoMFA). Prog. Clin. Biol. Res. 1989, 291, 161-165.
-
(1989)
Prog. Clin. Biol. Res.
, vol.291
, pp. 161-165
-
-
Cramer, R.D.R.1
Patterson, D.E.2
Bunce, J.D.3
-
16
-
-
0027944195
-
Molecular similarity indices in a comparative analysis (CoMSIA) of drug molecules to correlate and predict their biological activity
-
Klebe, G.; Abraham, U.; Mietzner, T. Molecular similarity indices in a comparative analysis (CoMSIA) of drug molecules to correlate and predict their biological activity. J. Med. Chem. 1994, 37, 4130-4146.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 4130-4146
-
-
Klebe, G.1
Abraham, U.2
Mietzner, T.3
-
17
-
-
0021871375
-
A computational procedure for determining energetically favorable binding sites on biologically important macromolecules
-
Goodford, P. J. A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. J. Med. Chem. 1985, 28, 849-857.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 849-857
-
-
Goodford, P.J.1
-
18
-
-
0034710718
-
Gridindependent descriptors (GRIND): a novel class of alignment-independent threedimensional molecular descriptors
-
Pastor, M.; Cruciani, G.; McLay, I.; Pickett, S.; Clementi, S. Gridindependent descriptors (GRIND): a novel class of alignment-independent threedimensional molecular descriptors. J. Med. Chem. 2000, 43, 323-324.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 323-324
-
-
Pastor, M.1
Cruciani, G.2
McLay, I.3
Pickett, S.4
Clementi, S.5
-
19
-
-
2442659094
-
Incorporating molecular shape into the alignment-free grid-independent descriptors
-
Fontaine, F.; Pastor, M.; Sanz, F.; Incorporating molecular shape into the alignment-free grid-independent descriptors. J. Med. Chem. 2004, 47, 2805-2815.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 2805-2815
-
-
Fontaine, F.1
Pastor, M.2
Sanz, F.3
-
20
-
-
28444472402
-
Improved approach for proteochemometrics modeling: application to organic compound-amine G protein-coupled receptor interactions
-
Lapinsh, M.; Prusis, P.; Uhlen, S.; Wikberg, J. E. S. Improved approach for proteochemometrics modeling: application to organic compound-amine G protein-coupled receptor interactions. Bioinformatics 2005, 21, 4289-4296.
-
(2005)
Bioinformatics
, vol.21
, pp. 4289-4296
-
-
Lapinsh, M.1
Prusis, P.2
Uhlen, S.3
Wikberg, J.E.S.4
-
21
-
-
0037161586
-
5D-QSAR: the key for simulating induced fit
-
Vedani, A.; Dobler, M. 5D-QSAR: the key for simulating induced fit? J. Med. Chem. 2002, 45, 2139-2149.
-
(2002)
J.Med. Chem.
, vol.45
, pp. 2139-2149
-
-
Vedani, A.1
Dobler, M.2
-
22
-
-
20144371130
-
Combining protein modeling and 6DQSAR: simulating the binding of structurally diverse ligands to the estrogen receptor
-
Vedani, A.; Dobler, M.; Lill, M. A. Combining protein modeling and 6DQSAR: simulating the binding of structurally diverse ligands to the estrogen receptor. J. Med. Chem. 2005, 48, 3700-3703.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 3700-3703
-
-
Vedani, A.1
Dobler, M.2
Lill, M.A.3
-
23
-
-
0023192524
-
Peptide quantitative structure-activity relationships, a multivariate approach
-
Hellberg, S.; Sj̈ostr̈om, M.; Skagerberg, B.; Wold, S. Peptide quantitative structure-activity relationships, a multivariate approach. J. Med. Chem. 1987, 30, 1126-1135.
-
(1987)
J. Med. Chem.
, vol.30
, pp. 1126-1135
-
-
Hellberg, S.1
Sj̈ostr̈om, M.2
Skagerberg, B.3
Wold, S.4
-
24
-
-
0032474777
-
New chemical descriptors relevant for the design of biologically active peptides: a multivariate characterization of 87 amino acids
-
Sandberg, M.; Eriksson, L.; Jonsson, J.; Sj̈ostr̈om, M.; Wold, S. New chemical descriptors relevant for the design of biologically active peptides: a multivariate characterization of 87 amino acids. J. Med. Chem. 1998, 41, 2481-2491.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2481-2491
-
-
Sandberg, M.1
Eriksson, L.2
Jonsson, J.3
Sj̈ostr̈om, M.4
Wold, S.5
-
25
-
-
33748457713
-
The drug designer's guide to selectivity
-
Gottfries, J. The drug designer's guide to selectivity. J. Chemometr. Intell. Lab. 2006, 83, 148-156.
-
(2006)
J. Chemometr. Intell. Lab.
, vol.83
, pp. 148-156
-
-
Gottfries, J.1
-
26
-
-
36148930244
-
Focused hierarchical design of peptide libraries-follow the lead
-
Muthas, D.; Lek, P. M.; Nurbo, J.; Karlen, A.; Lundstedt, T. Focused hierarchical design of peptide libraries-follow the lead. J. Chemometr. 2007, 21, 486-495.
-
(2007)
J. Chemometr.
, vol.21
, pp. 486-495
-
-
Muthas, D.1
Lek, P.M.2
Nurbo, J.3
Karlen, A.4
Lundstedt, T.5
-
27
-
-
0027215340
-
DNA and peptide sequences and chemical processes multivariately modelled by principal component analysis and partial least-squares projections to latent structures
-
Wold, S.; Jonsson, J.; Sj̈ostr̈om, M.; Sandberg, M.; R̈annar, S. DNA and peptide sequences and chemical processes multivariately modelled by principal component analysis and partial least-squares projections to latent structures. Anal. Chim. Acta 1993, 277, 239-253.
-
(1993)
Anal. Chim. Acta
, vol.277
, pp. 239-253
-
-
Wold, S.1
Jonsson, J.2
Sj̈ostr̈om, M.3
Sandberg, M.4
R̈annar, S.5
-
28
-
-
0025088861
-
Fourier methods for biosequence analysis
-
Benson, D. C. Fourier methods for biosequence analysis. Nucleic Acids Res. 1990, 18, 6305-6310.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6305-6310
-
-
Benson, D.C.1
-
29
-
-
0034687538
-
Prediction of protein subcellular locations by incorporating quasi-sequence-order effect
-
Chou, K. C. Prediction of protein subcellular locations by incorporating quasi-sequence-order effect. Biochem. Biophys. Res. Commun. 2000, 278, 477-483.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 477-483
-
-
Chou, K.C.1
-
30
-
-
0029047319
-
Prediction of protein folding class using global description of amino acid sequence
-
Dubchak, I.; Muchnik, I.; Holbrook, S. R.; Kim, S. H. Prediction of protein folding class using global description of amino acid sequence. Proc. Natl. Acad. Sci. USA 1995, 92, 8700-8704.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8700-8704
-
-
Dubchak, I.1
Muchnik, I.2
Holbrook, S.R.3
Kim, S.H.4
-
31
-
-
0035895752
-
Development of proteochemometrics: a novel technology of use for analysis of drug-receptor interactions
-
Lapinsh, M.; Prusis, P.; Gutcaits, A.; Lundstedt, T.; Wikberg, J. E. S. Development of proteochemometrics: a novel technology of use for analysis of drug-receptor interactions. Biochem. Biophys. Acta 2001, 1525, 180-190.
-
(2001)
Biochem. Biophys. Acta
, vol.1525
, pp. 180-190
-
-
Lapinsh, M.1
Prusis, P.2
Gutcaits, A.3
Lundstedt, T.4
Wikberg, J.E.S.5
-
32
-
-
11244311579
-
Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes
-
Lapinsh, M.; Veiksina, S.; Uhlen, S.; Petrovska, R.; Mutule, I.; Mutulis, F.; Yahorava, S.; Prusis, P.; Wikberg, J. E. S. Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes. Mol. Pharmacol. 2005, 67, 50-59.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 50-59
-
-
Lapinsh, M.1
Veiksina, S.2
Uhlen, S.3
Petrovska, R.4
Mutule, I.5
Mutulis, F.6
Yahorava, S.7
Prusis, P.8
Wikberg, J.E.S.9
-
33
-
-
34247233088
-
Proteochemometric modeling reveals the interaction site for Trp9 modified a-MSH peptides in melanocortin receptors
-
Lapinsh, M.; Prusis, P.; Petrovska, R.; Uhlen, S.; Mutule, I.; Veiksina, S.; Wikberg, J. E. S. Proteochemometric modeling reveals the interaction site for Trp9 modified a-MSH peptides in melanocortin receptors. Proteins: Struct. Funct. Bioinf . 2007, 67, 653-660.
-
(2007)
Proteins: Struct. Funct. Bioinf
, vol.67
, pp. 653-660
-
-
Lapinsh, M.1
Prusis, P.2
Petrovska, R.3
Uhlen, S.4
Mutule, I.5
Veiksina, S.6
Wikberg, J.E.S.7
-
34
-
-
34548329632
-
Proteochemometric analysis of small cyclic peptides' interaction with wild-type and chimeric melanocortin receptors
-
Kontijevskis, A.; Petrovska, R.; Mutule, I.; Uhlen, S.; Komorowski, J.; P., P.; Wikberg, J. E. S. Proteochemometric analysis of small cyclic peptides' interaction with wild-type and chimeric melanocortin receptors. Proteins 2007, 83-96.
-
(2007)
Proteins
, pp. 83-96
-
-
Kontijevskis, A.1
Petrovska, R.2
Mutule, I.3
Uhlen, S.4
Komorowski, J.5
Wikberg, J.E.S.6
-
35
-
-
0036264678
-
Proteochemometrics modeling of the interaction of amine G-protein coupled receptors with a diverse set of ligands
-
Lapinsh, M.; Prusis, P.; Wikberg, J. E. S. Proteochemometrics modeling of the interaction of amine G-protein coupled receptors with a diverse set of ligands. Mol. Pharmacol. 2002, 61, 1465-1475.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1465-1475
-
-
Lapinsh, M.1
Prusis, P.2
Wikberg, J.E.S.3
-
36
-
-
24744437347
-
A novel approach to fold recognition using sequence-derived properties from sets of structurally similar local fragments of proteins
-
Hvidsten, T. R.; Kryshtafovych, A.; Komorowski, J.; Fidelis, K. A novel approach to fold recognition using sequence-derived properties from sets of structurally similar local fragments of proteins. Bioinformatics 2003, 19 (Suppl. 2), ii81-ii91.
-
(2003)
Bioinformatics
, vol.19
, Issue.2 SUPPL
, pp. 281-291
-
-
Hvidsten, T.R.1
Kryshtafovych, A.2
Komorowski, J.3
Fidelis, K.4
-
37
-
-
33745369874
-
Hierarchical PLS modeling for predicting the binding of a comprehensive set of structurally diverse protein-ligand complexes
-
Lindstr̈om, A.; Pettersson, F.; Almqvist, F.; Berglund, A.; Kihlberg, J.; Linusson, A. Hierarchical PLS modeling for predicting the binding of a comprehensive set of structurally diverse protein-ligand complexes. J. Chem. Inf. Model. 2006, 46, 1154-1167.
-
(2006)
J. Chem. Inf. Model.
, vol.46
, pp. 1154-1167
-
-
Lindstr̈om, A.1
Pettersson, F.2
Almqvist, F.3
Berglund, A.4
Kihlberg, J.5
Linusson, A.6
-
38
-
-
33646462126
-
Development of quantitative structurebinding affinity relationship models based on novel geometrical chemical descriptors of the protein-ligand interfaces
-
Zhang, S.; Golbraikh, A.; Tropsha, A. Development of quantitative structurebinding affinity relationship models based on novel geometrical chemical descriptors of the protein-ligand interfaces. J. Med. Chem. 2006, 49, 2713-2724.
-
(2006)
J. Med. Chem.
, vol.49
, pp. 2713-2724
-
-
Zhang, S.1
Golbraikh, A.2
Tropsha, A.3
-
39
-
-
42949131067
-
Proteochemometric modeling of HIV protease susceptibility
-
Lapins, M.; Eklund, M.; Spjuth, O.; Prusis, P.; Wikberg, J. E. S. Proteochemometric modeling of HIV protease susceptibility. BMC Bioinf . 2008, 9, 181.
-
(2008)
BMC Bioinf .
, vol.9
, pp. 181
-
-
Lapins, M.1
Eklund, M.2
Spjuth, O.3
Prusis, P.4
Wikberg, J.E.S.5
-
40
-
-
84886071573
-
-
HIV Drug Research Centre,Accessed Nov. 2008.
-
HIV Drug Research Centre. http://hivdrc.org. Accessed Nov. 2008.
-
-
-
-
41
-
-
54249099193
-
Generalized proteochemometric model of multiple cytochrome P450 enzymes and their inhibitors
-
Kontijevskis, A.; Komorowski, J.; J. E. S.; W. Generalized proteochemometric model of multiple cytochrome P450 enzymes and their inhibitors. J. Chem. Inf. Model. 2008, 48, 1840-1850.
-
(2008)
J. Chem. Inf. Model.
, vol.48
, pp. 1840-1850
-
-
Kontijevskis, A.1
Komorowski, J.2
-
42
-
-
53249113059
-
Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases
-
Prusis, P.; Lapins, M.; Yahorava, S.; Petrovska, R.; Niyomrattanakit, P.; Katzenmeier, G.; Wikberg, J. E. S. Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases. Bioorg. Med. Chem. 2008, 16, 9369-9377.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 9369-9377
-
-
Prusis, P.1
Lapins, M.2
Yahorava, S.3
Petrovska, R.4
Niyomrattanakit, P.5
Katzenmeier, G.6
Wikberg, J.E.S.7
-
43
-
-
51349085386
-
Predicting PDZ domain-peptide interactions from primary sequences
-
Chen, J. R.; Chang, B. H.; Allen, J. E.; Stiffler, M. A.; MacBeath, G. Predicting PDZ domain-peptide interactions from primary sequences. Nat. Biotechnol. 2008, 26, 1041-1045.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 1041-1045
-
-
Chen, J.R.1
Chang, B.H.2
Allen, J.E.3
Stiffler, M.A.4
MacBeath, G.5
-
44
-
-
26944463088
-
Virtual screen for ligands of orphan G proteincoupled receptors
-
Bock, J. R.; Gough, D. A. Virtual screen for ligands of orphan G proteincoupled receptors. J. Chem. Inf. Model. 2005, 45, 1402-1414.
-
(2005)
J. Chem. Inf. Model.
, vol.45
, pp. 1402-1414
-
-
Bock, J.R.1
Gough, D.A.2
-
45
-
-
0035023445
-
Predicting protein-protein interactions from primary structure
-
Bock, J. R.; Gough, D. A. Predicting protein-protein interactions from primary structure. Bioinformatics 2001, 17, 455-460.
-
(2001)
Bioinformatics
, vol.17
, pp. 455-460
-
-
Bock, J.R.1
Gough, D.A.2
-
46
-
-
0037249217
-
Whole-proteome interaction mining
-
Bock, J. R.; Gough, D. A. Whole-proteome interaction mining. Bioinformatics 2003, 19, 125-134.
-
(2003)
Bioinformatics
, vol.19
, pp. 125-134
-
-
Bock, J.R.1
Gough, D.A.2
-
47
-
-
84886082883
-
-
Chemical Computing Group, Accessed Nov. 2008
-
Chemical Computing Group. http://www.chemcomp.com. Accessed Nov. 2008.
-
-
-
-
48
-
-
84885984531
-
-
Tripos, Accessed Nov. 2008.
-
Tripos. http://tripos.com. Accessed Nov. 2008.
-
-
-
-
49
-
-
84886038383
-
-
Strand Life Sciences.Accessed Nov. 2008.
-
Strand Life Sciences. http://www.strandls.com. Accessed Nov. 2008.
-
-
-
-
50
-
-
84886012473
-
-
Accelrys Software.Accessed Nov. 2008.
-
Accelrys Software. http://accelrys.com. Accessed Nov. 2008.
-
-
-
-
51
-
-
84885999580
-
-
Talete. Accessed Nov. 2008.
-
Talete. http://www.talete.mi.it. Accessed Nov. 2008.
-
-
-
-
52
-
-
84886082578
-
-
MIA S.r.l.Accessed Nov. 2008.
-
MIA S.r.l. http://miasrl.com/. Accessed Nov. 2008.
-
-
-
-
53
-
-
84886063733
-
-
Umetrics. Accessed Nov. 2008.
-
Umetrics. http://www.umetrics.com/. Accessed Nov. 2008.
-
-
-
-
54
-
-
84885990325
-
-
Camo. Accessed Nov. 2008.
-
Camo. http://www.camo.com. Accessed Nov. 2008.
-
-
-
-
55
-
-
84885991693
-
-
SPSS. Accessed Nov. 2008.
-
SPSS. http://spss.com/. Accessed Nov. 2008.
-
-
-
-
56
-
-
84886048170
-
-
SAS. Accessed Nov. 2008.
-
SAS. http://www.sas.com/. Accessed Nov. 2008.
-
-
-
-
57
-
-
1342288004
-
The Jalview Java alignment editor
-
Clamp, M.; Cuff, J.; Searle, S. M.; Barton, G. J. The Jalview Java alignment editor. Bioinformatics 2004, 20, 426-427.
-
(2004)
Bioinformatics
, vol.20
, pp. 426-427
-
-
Clamp, M.1
Cuff, J.2
Searle, S.M.3
Barton, G.J.4
-
58
-
-
84886073819
-
-
JalView. Accessed Nov. 2008.
-
JalView. http://www.jalview.org. Accessed Nov. 2008.
-
-
-
-
59
-
-
84886021059
-
-
The R Project for Statistical Computing.Accessed Nov. 2008.
-
The R Project for Statistical Computing. http://www.r-project.org. Accessed Nov. 2008.
-
-
-
-
60
-
-
33847772616
-
Bioclipse: an open source workbench for chemo- and bioinformatics
-
Spjuth, O.; Helmus, T.;Willighagen, E. L.; Kuhn, S.; Eklund, E.;Wagener, J.; Murray-Rust, P.; Steinbeck, C.; Wikberg, J. E. S. Bioclipse: an open source workbench for chemo- and bioinformatics. BMC Bioinf . 2007, 8, 59.
-
(2007)
BMC Bioinf
, vol.8
, pp. 59
-
-
Spjuth, O.1
Helmus, T.2
Willighagen, E.L.3
Kuhn, S.4
Eklund, E.5
Wagener, J.6
Murray-Rust, P.7
Steinbeck, C.8
Wikberg, J.E.S.9
-
61
-
-
84885997300
-
-
Bioclipse. Accessed Nov. 2008.
-
Bioclipse. http://www.bioclipse.net. Accessed Nov. 2008.
-
-
-
-
62
-
-
21044459901
-
Evolution ofWeb services in bioinformatics
-
Neerincx, P. B.; Leunissen, J. A. Evolution ofWeb services in bioinformatics. Brief Bioinf . 2005, 6, 178-188.
-
(2005)
Brief Bioinf
, vol.6
, pp. 178-188
-
-
Neerincx, P.B.1
Leunissen, J.A.2
-
63
-
-
20444445386
-
Web services in the life sciences
-
Curcin, V.; Ghanem, M.; Guo, Y. Web services in the life sciences. Drug Discov. Today 2005, 10, 865-871.
-
(2005)
Drug Discov. Today
, vol.10
, pp. 865-871
-
-
Curcin, V.1
Ghanem, M.2
Guo, Y.3
-
64
-
-
84886048927
-
-
Eclipse. Accessed Nov. 2008.
-
Eclipse. http://www.eclipse.org. Accessed Nov. 2008.
-
-
-
-
65
-
-
84886061724
-
-
Genetta Soft. Accessed Nov. 2008.
-
Genetta Soft. http://www.genettasoft.com. Accessed Nov. 2008.
-
-
-
-
66
-
-
33845762340
-
Multi-target therapeutics: when the whole is greater than the sum of the parts
-
Zimmermann, G. R.; Lehar, J.; Keith, C. T. Multi-target therapeutics: when the whole is greater than the sum of the parts. Drug Discov. Today. 2007, 12, 34-42.
-
(2007)
Drug Discov. Today.
, vol.12
, pp. 34-42
-
-
Zimmermann, G.R.1
Lehar, J.2
Keith, C.T.3
-
67
-
-
38949114341
-
Chemistry for everyone
-
Murray-Rust, P. Chemistry for everyone. Nature 2008, 451, 648-651.
-
(2008)
Nature
, vol.451
, pp. 648-651
-
-
Murray-Rust, P.1
-
68
-
-
84885978926
-
-
Web 2.0.Accessed Nov. 2008.
-
Web 2.0. http://en.wikipedia.org/wiki/Web2. Accessed Nov. 2008.
-
-
-
-
69
-
-
84886005478
-
-
HUPO. Accessed Nov. 2008.
-
HUPO. http://www.hupo.org/. Accessed Nov. 2008.
-
-
-
-
70
-
-
84886027694
-
-
MGED Society. Accessed Nov. 2008.
-
MGED Society. http://www.mged.org/. Accessed Nov. 2008.
-
-
-
-
71
-
-
84886055390
-
-
NIMH Psychoactive Drug Screening Program. Accessed Nov. 2008.
-
NIMH Psychoactive Drug Screening Program. http://pdsp.med.unc.edu. Accessed Nov. 2008.
-
-
-
-
72
-
-
84886060062
-
-
EMBL-EBI, Swiss-Prot. Accessed Nov. 2008.
-
EMBL-EBI, Swiss-Prot. http://www.ebi.ac.uk/swissprot/. Accessed Nov. 2008.
-
-
-
-
73
-
-
0031565726
-
An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors
-
Baldwin, J. M.; Schertler, G. F.; Unger, V. M. An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors. J. Mol. Biol. 1997, 272, 144-164.
-
(1997)
J. Mol. Biol.
, vol.272
, pp. 144-164
-
-
Baldwin, J.M.1
Schertler, G.F.2
Unger, V.M.3
-
74
-
-
84885969530
-
-
Perl. Accessed Nov. 2008.
-
Perl. http://www.perl.org/. Accessed Nov. 2008.
-
-
-
-
75
-
-
84886049631
-
-
Symyx MDL. Accessed Nov. 2008.
-
Symyx MDL. http://www.mdli.com/. Accessed Nov. 2008.
-
-
-
-
76
-
-
84886033980
-
-
Introduction to Pharmaceutical bioinformatics, bakleaf, Stockholm ISBN 978-91-979403-0-6
-
Wikberg, J. E. S.; Eklund, M.; Willighagen, E. L.; Spjuth, O.; Lapins, M.; Engkrist, O.; Aluarsson, J.; Introduction to Pharmaceutical bioinformatics, 2011 bakleaf, Stockholm ISBN 978-91-979403-0-6.
-
(2011)
-
-
Wikberg, J.E.S.1
Eklund, M.2
Willighagen, E.L.3
Spjuth, O.4
Lapins, M.5
Engkrist, O.6
Aluarsson, J.7
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