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Volumn 9, Issue , 2013, Pages 966-973

Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway

Author keywords

CCG 1423; Click ligation; Photoaffinity labeling; Rho pathway inhibitor; Tag free photoprobe; Target identification

Indexed keywords


EID: 84878162260     PISSN: None     EISSN: 18605397     Source Type: Journal    
DOI: 10.3762/bjoc.9.111     Document Type: Article
Times cited : (22)

References (25)
  • 1
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • DOI 10.1016/S0092-8674(03)00278-2
    • Miralles, F.; Posern, G.; Zaromytidou, A.-I.; Treisman, R. Cell 2003, 113, 329-342. doi:10.1016/S0092-8674(03)00278-2 (Pubitemid 36556115)
    • (2003) Cell , vol.113 , Issue.3 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.-I.3    Treisman, R.4
  • 2
    • 33947727502 scopus 로고    scopus 로고
    • Myocardin-related transcription factors: Critical coactivators regulating cardiovascular development and adaptation
    • DOI 10.1161/01.RES.0000259563.61091.e8, PII 0000301220070316000006
    • Parmacek, M. S. Circ. Res. 2007, 100, 633-644. doi:10.1161/01.RES. 0000259563.61091.e8 (Pubitemid 46594877)
    • (2007) Circulation Research , vol.100 , Issue.5 , pp. 633-644
    • Parmacek, M.S.1
  • 3
    • 33745152386 scopus 로고    scopus 로고
    • The myocardin family of transcriptional coactivators: Versatile regulators of cell growth, migration, and myogenesis
    • DOI 10.1101/gad.1428006
    • Pipes, G. C. T.; Creemers, E. E.; Olson, E. N. Genes Dev. 2006, 20, 1545-1556. doi:10.1101/gad.1428006 (Pubitemid 43901093)
    • (2006) Genes and Development , vol.20 , Issue.12 , pp. 1545-1556
    • Pipes, G.C.T.1    Creemers, E.E.2    Olson, E.N.3
  • 12
    • 0028808348 scopus 로고
    • doi:10.1016/0040-4020(95)00598-3
    • Fleming, S. A. Tetrahedron 1995, 51, 12479-12520. doi:10.1016/0040- 4020(95)00598-3
    • (1995) Tetrahedron , vol.51 , pp. 12479-12520
    • Fleming S., .A.1
  • 13
    • 0033951038 scopus 로고    scopus 로고
    • Using photolabile ligands in drug discovery and development
    • DOI 10.1016/S0167-7799(99)01402-X, PII S016777999901402X
    • Dormán, G.; Prestwich, G. D. Trends Biotechnol. 2000, 18, 64-77. doi:10.1016/S0167-7799(99)01402-X (Pubitemid 30084698)
    • (2000) Trends in Biotechnology , vol.18 , Issue.2 , pp. 64-77
    • Dorman, G.1    Prestwich, G.D.2
  • 14
    • 27144510184 scopus 로고    scopus 로고
    • Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling
    • DOI 10.1038/nbt1149, PII N1149
    • Evans, M. J.; Saghatelian, A.; Sorensen, E. J.; Cravatt, B. F. Nat. Biotechnol. 2005, 23, 1303-1307. doi:10.1038/nbt1149 (Pubitemid 41486859)
    • (2005) Nature Biotechnology , vol.23 , Issue.10 , pp. 1303-1307
    • Evans, M.J.1    Saghatelian, A.2    Sorensen, E.J.3    Cravatt, B.F.4
  • 15
    • 1942522084 scopus 로고    scopus 로고
    • Profiling enzyme activities in vivo using click chemistry methods
    • DOI 10.1016/j.chembiol.2004.03.012, PII S1074552104000961
    • Speers, A. E.; Cravatt, B. F. Chem. Biol. 2004, 11, 535-546. doi:10.1016/j.chembiol.2004.03.012 (Pubitemid 38511759)
    • (2004) Chemistry and Biology , vol.11 , Issue.4 , pp. 535-546
    • Speers, A.E.1    Cravatt, B.F.2
  • 17
    • 84867573488 scopus 로고    scopus 로고
    • doi:10.1016/j.bmc.2012.09.010
    • Lapinsky, D. J. Bioorg. Med. Chem. 2012, 20, 6237-6247. doi:10.1016/j.bmc.2012.09.010
    • (2012) J. Bioorg. Med. Chem. , vol.20 , pp. 6237-6247
    • Lapinsky, D.1
  • 18
    • 34548118304 scopus 로고    scopus 로고
    • Activity-based protein profiling for type I methionine aminopeptidase by using photo-affinity trimodular probes
    • DOI 10.1002/cbic.200700148
    • Qiu, W.-W.; Xu, J.; Li, J.-Y.; Li, J.; Nan, F.-J. ChemBioChem 2007, 8, 1351-1358. doi:10.1002/cbic.200700148 (Pubitemid 47300324)
    • (2007) ChemBioChem , vol.8 , Issue.12 , pp. 1351-1358
    • Qiu, W.-W.1    Xu, J.2    Li, J.-Y.3    Li, J.4    Nan, F.-J.5
  • 19
    • 0037462106 scopus 로고    scopus 로고
    • Activity-based protein profiling in vivo using a copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition
    • DOI 10.1021/ja034490h
    • Speers, A. E.; Adam, G. C.; Cravatt, B. F. J. Am. Chem. Soc. 2003, 125, 4686-4687. doi:10.1021/ja034490h (Pubitemid 36505343)
    • (2003) Journal of the American Chemical Society , vol.125 , Issue.16 , pp. 4686-4687
    • Speers, A.E.1    Adam, G.C.2    Cravatt, B.F.3
  • 20
    • 39549102872 scopus 로고    scopus 로고
    • Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes
    • DOI 10.1021/ja074138u
    • Salisbury, C. M.; Cravatt, B. F. J. Am. Chem. Soc. 2008, 130, 2184-2194. doi:10.1021/ja074138u (Pubitemid 351287995)
    • (2008) Journal of the American Chemical Society , vol.130 , Issue.7 , pp. 2184-2194
    • Salisbury, C.M.1    Cravatt, B.F.2
  • 22
    • 77955629600 scopus 로고    scopus 로고
    • doi:10.2174/092986710791959747
    • Li, X.; Hu, Y. Curr. Med. Chem. 2010, 17, 3030-3044. doi:10.2174/ 092986710791959747
    • (2010) Curr. Med. Chem. , vol.17 , pp. 3030-3044
    • Li, X.1    Hu, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.