Increased levels of Treg cells in bronchoalveolar lavage fluid and induced sputum of patients with active pulmonary sarcoidosis

European Journal of Medical Research

Volumn 14, Issue SUPPL.4, 2009, Pages 165-169

  Mroz, R M ^a   Korniluk, M ^a   Stasiak Barmuta, A ^b   Ossolinska, M ^a   Chyczewska, E ^a  

^a Department of Chest Diseases and Tuberculosis ^*  (Poland)

^b MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

hypersensitivity pneumonitis; sarcoidosis; T cells; Treg cells

Indexed keywords

ADULT; AGED; ARTICLE; CD4 CD8 RATIO; FEMALE; HUMAN; IMMUNOLOGY; LUNG LAVAGE; MALE; MIDDLE AGED; PROSPECTIVE STUDY; REGULATORY T LYMPHOCYTE; SARCOIDOSIS; SPUTUM;

ADULT; AGED; BRONCHOALVEOLAR LAVAGE FLUID; CD4-CD8 RATIO; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SARCOIDOSIS, PULMONARY; SPUTUM; T-LYMPHOCYTES, REGULATORY;

EID: 77955506298     PISSN: 09492321     EISSN: 2047783X     Source Type: Journal    
DOI: 10.1186/2047-783X-14-S4-165     Document Type: Article

References (19)

1. ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and other Granulomatous Disorders. Hunninghake GW, Costabel U, Ando M, Baughman R, Cordier JF, du Bois R, Eklund A, Kitaichi M, Lynch J, Rizzato G, Rose C, Selroos O, Semenzato G, Sharma OP, Sarcoidosis Vasc Diffuse Lung Dis 1999 16 2 149 73 10560120
2. Sarcoidosis: histopathological definition and clinical diagnosis. Mitchell DN, Scadding JG, Heard BE, Hinson KF, J Clin Pathol 1977 30 5 395 408 10.1136/jcp.30.5.395 325017 (Pubitemid 8108621)
3. Hypersensitivity pneumonitis. Fink JN, Clin Chest Med 1992 13 303 9 1511555
4. Hypersensitivity pneumonitis: a noninfectious granulomatosis. Sharma OP, Fujimura N, Semin Respir Infect 1995 10 96 106 7569404
5. Comparison of cellular composition of induced sputum, bronchial washings and bronchoalveolar lavage fluid in sarcoidosis, hypersensitivity pneumonitis and COPD. Mráz RM, Chyczewska E, Korniluk M, Stasiak-Barmuta A, Ossoli-ska M, Pneumonol Alergol Pol 2002 70 9-10 468 77 12710099 (Pubitemid 35423760)
6. Comparison of induced sputum and bronchoalveolar lavage fluid cell profile during the treatment of pulmonary sarcoidosis. Mroz RM, Korniluk M, Stasiak-Barmuta A, Chyczewska E, J Physiol Pharmacol 2007 58 Suppl 5(2) 445 52 18204157 (Pubitemid 351346693)
7. The immune paradox of sarcoidosis and regulatory T cells. Miyara M, Amoura Z, Parizot C, Badoual C, Dorgham K, Trad S, Kambouchner M, Valeyre D, Chapelon-Abric C, Debré P, Piette JC, Gorochov G, J Exp Med 2006 203 2 359 70 10.1084/jem.20050648 16432251 (Pubitemid 43290845)
8. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Sakaguchi S, Annu Rev Immunol 2004 22 531 62 10.1146/annurev.immunol.21.120601.141122 15032588 (Pubitemid 38680433)
9. Regulatory T cells and immune tolerance. Sakaguchi S, Yamaguchi T, Nomura T, Ono M, Cell 2008 133 775 87 10.1016/j.cell.2008.05.009 18510923 (Pubitemid 351707693)
10. General considerations for lung function testing. Miller MR, Crapo R, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J, ATS/ERS Task Force, Eur Respir J 2005 26 1 153 61 10.1183/09031936.05.00034505 15994402 (Pubitemid 40945944)
11. Report of the European Society of Pneumology Task Group. Technical recommendations and guidelines for bronchoalveolar lavage (BAL), Eur Respir J 1989 2 6 561 85 2663535
12. Report of ERS Task Force: guidelines for measurement of a cellular components and standardization of BAL. Haslam PL, Baughman RP, Eur Respir J 1999 14 2 245 8 10515395 (Pubitemid 29461283)
13. Bronchoalveolar lavage and lung histology. Comparative analysis of inflammatory and immunocompetent cells in patients with sarcoidosis and hypersensitivity pneumonitis. Semenzato G, Chilosi M, Ossi E, Trentin L, Pizzolo G, Cipriani A, Agostini C, Zambello R, Marcer G, Gasparotto G, Am Rev Respir Dis 1985 132 2 400 4 3896081 (Pubitemid 15229403)
14. Prognostic value of bronchoalveolar lavage in sarcoidosis: the critical influence of disease presentation. Ward K, O'Connor C, Odlum C, FitzGerald MX, Thorax 1989 44 1 6 12 10.1136/thx.44.1.6 2928989 (Pubitemid 19035379)
15. Increased levels of interleukin-12 and interleukin 18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis. Mroz RM, Korniluk M, Stasiak-Barmuta A, Chyczewska E, J Physiol Pharmacol 2008 59 Suppl 6 507 13 19218675
16. Upregulation of Th1 cytokine profile (IL-12, IL-18) in bronchoalveolar lavage fluid of patients with hypersensitivity pneumonitis. Mroz RM, Korniluk M, Stasiak-Barmuta A, Chyczewska E, J Physiol Pharmacol 2008 59 Suppl 6 499 505 19218674
17. Lung fibrosis in hypersensitivity pneumonitis. Association with CD4+ but not CD8+ cell dominant alveolitis and insidious onset. Murayama J, Yoshizawa Y, Ohtsuka M, Hasegawa S, Chest 1993 104 38 43 10.1378/chest.104.1.38 8325114 (Pubitemid 23204525)
18. FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions. Taflin C, Miyara M, Nochy D, Valeyre D, Naccache JM, Altare F, Salek-Peyron P, Badoual C, Bruneval P, Haroche J, Mathian A, Amoura Z, Hill G, Gorochov G, Am J Pathol 2009 174 2 497 508 10.2353/ajpath.2009.080580 19147826
19. Idali F, Wahlström J, Müller-Suur C, Eklund A, Grunewald J, Clin Exp Immunol 2008 152 1 127 37 10.1111/j.1365-2249.2008.03609.x 18279440 (Pubitemid 351347561)